|
1
|
Twelve positions in a β-lactamase that can expand its substrate spectrum with a single amino acid substitution.
|
PLoS One
|
2012
|
1.03
|
|
2
|
The Boston-type craniosynostosis mutation MSX2 (P148H) results in enhanced susceptibility of MSX2 to ubiquitin-dependent degradation.
|
J Biol Chem
|
2008
|
0.93
|
|
3
|
Regioselectivity prediction of CYP1A2-mediated phase I metabolism.
|
J Chem Inf Model
|
2008
|
0.87
|
|
4
|
Substrate spectrum extension of PenA in Burkholderia thailandensis with a single amino acid deletion, Glu168del.
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Antimicrob Agents Chemother
|
2012
|
0.85
|
|
5
|
SABA (secondary structure assignment program based on only alpha carbons): a novel pseudo center geometrical criterion for accurate assignment of protein secondary structures.
|
BMB Rep
|
2011
|
0.82
|
|
6
|
EaMEAD: Activation energy prediction of cytochrome P450 mediated metabolism with effective atomic descriptors.
|
J Chem Inf Model
|
2009
|
0.81
|
|
7
|
New combined model for the prediction of regioselectivity in cytochrome P450/3A4 mediated metabolism.
|
J Chem Inf Model
|
2008
|
0.80
|
|
8
|
Calculation of the solvation free energy of neutral and ionic molecules in diverse solvents.
|
J Chem Inf Model
|
2010
|
0.78
|
|
9
|
A generalized G-SFED continuum solvation free energy calculation model.
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Proc Natl Acad Sci U S A
|
2013
|
0.78
|
|
10
|
Development of surface-SFED models for polar solvents.
|
J Chem Inf Model
|
2012
|
0.77
|
|
11
|
Mutational analysis of human tumor necrosis factor-alpha.
|
Biotechnol Lett
|
2005
|
0.77
|
|
12
|
Ligand aligning method for molecular docking: alignment of property-weighted vectors.
|
J Chem Inf Model
|
2012
|
0.76
|
|
13
|
A robust method for searching the smallest set of smallest rings with a path-included distance matrix.
|
Proc Natl Acad Sci U S A
|
2009
|
0.75
|
|
14
|
Development of human tumor necrosis factor-alpha muteins with improved therapeutic potential.
|
BMB Rep
|
2009
|
0.75
|
|
15
|
Amide I bands of terminally blocked alanine in solutions investigated by infrared spectroscopy and density functional theory calculation: hydrogen-bonding interactions and solvent effects.
|
J Phys Chem B
|
2009
|
0.75
|