David L Wiest

Author PubWeight™ 46.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint. Immunity 2007 2.39
2 Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage. Immunity 2005 2.11
3 Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J Immunol 2007 1.88
4 Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development. Nat Immunol 2005 1.75
5 Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation. Immunity 2006 1.70
6 High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry. Sci STKE 2007 1.51
7 Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. Immunity 2009 1.43
8 Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B. Blood 2012 1.29
9 Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival. J Immunol 2007 1.24
10 A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. Cancer Res 2008 1.19
11 T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. Blood 2006 1.15
12 Early growth response genes regulate B cell development, proliferation, and immune response. J Immunol 2008 1.14
13 Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs. Dev Cell 2013 1.11
14 Early growth response transcription factors are required for development of CD4(-)CD8(-) thymocytes to the CD4(+)CD8(+) stage. J Immunol 2002 1.07
15 Egr2 is required for Bcl-2 induction during positive selection. J Immunol 2008 1.04
16 The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1. PLoS Genet 2013 1.02
17 Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells. J Immunol 2003 1.02
18 CD45-deficient severe combined immunodeficiency caused by uniparental disomy. Proc Natl Acad Sci U S A 2012 0.99
19 Subversion of T lineage commitment by PU.1 in a clonal cell line system. Dev Biol 2005 0.98
20 Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection. J Immunol 2005 0.95
21 Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals. Int Immunol 2007 0.94
22 The role of MAPKs in B cell receptor-induced down-regulation of Egr-1 in immature B lymphoma cells. J Biol Chem 2006 0.93
23 Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors. J Immunol 2011 0.92
24 Recurrent chromosomal rearrangements implicate oncogenes contributing to T-cell lymphomagenesis in Lck-MyrAkt2 transgenic mice. Genes Chromosomes Cancer 2009 0.92
25 A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes. J Immunol 2013 0.91
26 Pre-TCR-induced beta-catenin facilitates traversal through beta-selection. J Immunol 2009 0.91
27 Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice. Semin Immunol 2010 0.91
28 Recent insights into the signals that control alphabeta/gammadelta-lineage fate. Immunol Rev 2006 0.91
29 Sustained expression of pre-TCR induced beta-catenin in post-beta-selection thymocytes blocks T cell development. J Immunol 2009 0.91
30 Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development. Genesis 2010 0.89
31 Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. J Immunol 2007 0.89
32 Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells. Proc Natl Acad Sci U S A 2012 0.88
33 Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery. Mol Ther 2007 0.88
34 Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation. J Immunol 2004 0.86
35 Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mamm Genome 2009 0.86
36 Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells. J Immunol 2010 0.86
37 Cutting edge: Intrinsic programming of thymic γδT cells for specific peripheral tissue localization. J Immunol 2010 0.86
38 In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement. Hum Gene Ther 2006 0.83
39 The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification. J Exp Med 2014 0.83
40 Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling. J Immunol 2012 0.82
41 Fli-1 regulates the DN2 to DN3 thymocyte transition and promotes γδ T-cell commitment by enhancing TCR signal strength. Eur J Immunol 2014 0.78
42 Enforcement of γδ-lineage commitment by the pre-T-cell receptor in precursors with weak γδ-TCR signals. Proc Natl Acad Sci U S A 2014 0.77
43 Using the Zebrafish Model to Study T Cell Development. Methods Mol Biol 2016 0.77
44 Origins of gammadeltaT cells: a forum for opposing perspectives. Semin Immunol 2010 0.76