David E Minnikin

Author PubWeight™ 31.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum. Microbiology 2002 1.97
2 Detection and molecular characterization of 9,000-year-old Mycobacterium tuberculosis from a Neolithic settlement in the Eastern Mediterranean. PLoS One 2008 1.92
3 Metagenomic analysis of tuberculosis in a mummy. N Engl J Med 2013 1.89
4 Genome-wide comparison of medieval and modern Mycobacterium leprae. Science 2013 1.81
5 Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis. Biochem J 2002 1.35
6 Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol. Mol Microbiol 2005 1.29
7 A type II pathway for fatty acid biosynthesis presents drug targets in Plasmodium falciparum. Antimicrob Agents Chemother 2003 1.26
8 LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum. J Biol Chem 2005 1.20
9 A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection. J Clin Invest 2011 1.07
10 Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural principles in mycolic acids. Microbiology 2002 1.04
11 Mycocerosic acid biomarkers for the diagnosis of tuberculosis in the Coimbra Skeletal Collection. Tuberculosis (Edinb) 2009 1.04
12 Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity. Microbiology 2002 1.00
13 Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis. Proc Biol Sci 2009 0.97
14 Detection of Mycobacterium tuberculosis in sputum by gas chromatography-mass spectrometry of methyl mycocerosates released by thermochemolysis. PLoS One 2012 0.97
15 Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones. Chem Biol 2008 0.95
16 Temperature dependence of the Langmuir monolayer packing of mycolic acids from Mycobacterium tuberculosis. Biochim Biophys Acta 2005 0.95
17 Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin. J Immunol 2009 0.93
18 Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG. Biochim Biophys Acta 2007 0.93
19 Symmetrical and unsymmetrical analogues of isoxyl; active agents against Mycobacterium tuberculosis. Bioorg Med Chem Lett 2006 0.90
20 Detection and strain typing of ancient Mycobacterium leprae from a medieval leprosy hospital. PLoS One 2013 0.89
21 A simple mycobacterial monomycolated glycerol lipid has potent immunostimulatory activity. J Immunol 2009 0.88
22 Osteological and biomolecular evidence of a 7000-year-old case of hypertrophic pulmonary osteopathy secondary to tuberculosis from neolithic hungary. PLoS One 2013 0.87
23 Mycobacterium tuberculosis complex lipid virulence factors preserved in the 17,000-year-old skeleton of an extinct bison, Bison antiquus. PLoS One 2012 0.87
24 Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme. Bioorg Med Chem Lett 2003 0.87
25 Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme. Bioorg Med Chem Lett 2004 0.84
26 Development and optimization of a gas chromatography/mass spectrometry method for the analysis of thermochemolytic degradation products of phthiocerol dimycocerosate waxes found in Mycobacterium tuberculosis. Rapid Commun Mass Spectrom 2013 0.82
27 Novel prenyl-linked benzophenone substrate analogues of mycobacterial mannosyltransferases. Biochem J 2004 0.79
28 Differential conformational behaviors of alpha-mycolic acids in Langmuir monolayers and computer simulations. Chem Phys Lipids 2010 0.79
29 Adjuvant properties of a simplified C32 monomycolyl glycerol analogue. Bioorg Med Chem Lett 2009 0.78
30 Synthesis and properties of methyl 5-(1'R,2'S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids. Chem Phys Lipids 2004 0.75
31 Facile synthesis of (Z)-tetracos-5-enoic acid and racemic cis-4-(2-octadecylcyclopropane-1-yl)-butanoic acid. Chem Phys Lipids 2003 0.75
32 Conformational folding of mycobacterial methoxy- and ketomycolic acids facilitated by α-methyl trans-cyclopropane groups rather than cis-cyclopropane units. Microbiology 2013 0.75