Published in Comp Biochem Physiol C Toxicol Pharmacol on September 06, 2008
An invertebrate hyperglycemic model for the identification of anti-diabetic drugs. PLoS One (2011) 0.92
Porphyromonas gingivalis peptidoglycans induce excessive activation of the innate immune system in silkworm larvae. J Biol Chem (2010) 0.86
Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources. BMC Pharmacol (2010) 0.83
RIP-seq of BmAgo2-associated small RNAs reveal various types of small non-coding RNAs in the silkworm, Bombyx mori. BMC Genomics (2013) 0.81
Developmental Changes for the Hemolymph Metabolome of Silkworm (Bombyx mori L.). J Proteome Res (2015) 0.81
Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph. BMC Pharmacol Toxicol (2012) 0.81
Fluorescence imaging for a noninvasive in vivo toxicity-test using a transgenic silkworm expressing green fluorescent protein. Sci Rep (2015) 0.79
Display of human proinsulin on the Bacillus subtilis spore surface for oral administration. Curr Microbiol (2013) 0.79
Advantages of the Silkworm As an Animal Model for Developing Novel Antimicrobial Agents. Front Microbiol (2017) 0.78
Primed Immune Responses Triggered by Ingested Bacteria Lead to Systemic Infection Tolerance in Silkworms. PLoS One (2015) 0.78
Diabetic silkworms for evaluation of therapeutically effective drugs against type II diabetes. Sci Rep (2015) 0.77
Surface display of human growth hormone on Bacillus subtilis spores for oral administration. Curr Microbiol (2013) 0.76
Effect of Vitamin A on Listeria monocytogenes Infection in a Silkworm Model. PLoS One (2016) 0.75
The effect of bovine milk on the growth of Bombyx mori. J Insect Sci (2013) 0.75
Reproductive toxicity and gender differences induced by cadmium telluride quantum dots in an invertebrate model organism. Sci Rep (2016) 0.75
An in vivo invertebrate evaluation system for identifying substances that suppress sucrose-induced postprandial hyperglycemia. Sci Rep (2016) 0.75
Antioxidative properties of 4-methylumbelliferone are related to antibacterial activity in the silkworm (Bombyx mori) digestive tract. J Comp Physiol B (2014) 0.75
An invertebrate infection model for evaluating anti-fungal agents against dermatophytosis. Sci Rep (2017) 0.75
Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels. Cancer Res (2008) 2.20
Silkworm larvae as an animal model of bacterial infection pathogenic to humans. Microb Pathog (2002) 1.69
Pleiotropic roles of polyglycerolphosphate synthase of lipoteichoic acid in growth of Staphylococcus aureus cells. J Bacteriol (2008) 1.67
Quantitative evaluation of the therapeutic effects of antibiotics using silkworms infected with human pathogenic microorganisms. Antimicrob Agents Chemother (2004) 1.67
Characterization of the Staphylococcus aureus mprF gene, involved in lysinylation of phosphatidylglycerol. Microbiology (2004) 1.59
Silkworm pathogenic bacteria infection model for identification of novel virulence genes. Mol Microbiol (2005) 1.53
Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence. PLoS Pathog (2011) 1.34
A nucleotide switch in the Escherichia coli DnaA protein initiates chromosomal replication: evidnece from a mutant DnaA protein defective in regulatory ATP hydrolysis in vitro and in vivo. J Biol Chem (2002) 1.32
Inhibitory effects of basic or neutral phospholipid on acidic phospholipid-mediated dissociation of adenine nucleotide bound to DnaA protein, the initiator of chromosomal DNA replication. J Biol Chem (2003) 1.31
Colony spreading in Staphylococcus aureus. J Bacteriol (2006) 1.30
DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication. J Biol Chem (2004) 1.27
Novel DNA binding protein SarZ contributes to virulence in Staphylococcus aureus. Mol Microbiol (2006) 1.25
The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. J Biol Chem (2009) 1.21
A role of the Duffy antigen for the maintenance of plasma chemokine concentrations. Biochem Biophys Res Commun (2003) 1.19
Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence. PLoS Pathog (2013) 1.16
Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha. Genes Cells (2003) 1.14
A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions. Int Immunol (2003) 1.13
Phosphodiesterase activity of CvfA is required for virulence in Staphylococcus aureus. J Biol Chem (2007) 1.10
SDT1/SSM1, a multicopy suppressor of S-II null mutant, encodes a novel pyrimidine 5'-nucleotidase. J Biol Chem (2002) 1.08
Transcription elongation factor S-II maintains transcriptional fidelity and confers oxidative stress resistance. Genes Cells (2003) 1.08
Stimulation of RNA polymerase II transcript cleavage activity contributes to maintain transcriptional fidelity in yeast. Genes Cells (2007) 1.07
A novel gene, fudoh, in the SCCmec region suppresses the colony spreading ability and virulence of Staphylococcus aureus. PLoS One (2008) 1.05
Dual subcellular localization in the endoplasmic reticulum and peroxisomes and a vital role in protecting against oxidative stress of fatty aldehyde dehydrogenase are achieved by alternative splicing. J Biol Chem (2007) 1.04
Intestinal resident yeast Candida glabrata requires Cyb2p-mediated lactate assimilation to adapt in mouse intestine. PLoS One (2011) 1.02
The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor. J Biol Chem (2007) 1.02
[Identification of novel therapeutically effective antibiotics using silkworm infection model]. Yakugaku Zasshi (2012) 1.01
Sugar-responsive gene expression and the agr system are required for colony spreading in Staphylococcus aureus. Microb Pathog (2011) 1.01
Identification of lipoteichoic acid as a ligand for draper in the phagocytosis of Staphylococcus aureus by Drosophila hemocytes. J Immunol (2009) 1.01
Activation of the silkworm cytokine by bacterial and fungal cell wall components via a reactive oxygen species-triggered mechanism. J Biol Chem (2007) 0.98
Isolation and mutation site determination of the temperature-sensitive murB mutants of Staphylococcus aureus. FEMS Microbiol Lett (2003) 0.97
Dual topology of functional Toll-like receptor 3 expression in human hepatocellular carcinoma: differential signaling mechanisms of TLR3-induced NF-kappaB activation and apoptosis. Int J Oncol (2008) 0.97
Transcription elongation factor S-II is required for definitive hematopoiesis. Mol Cell Biol (2006) 0.95
Antimicrobial action mechanism of flavonoids from Dorstenia species. Drug Discov Ther (2013) 0.95
Channel-forming membrane permeabilization by an antibacterial protein, sapecin: determination of membrane-buried and oligomerization surfaces by NMR. J Biol Chem (2003) 0.94
Regulation of exoprotein gene expression by the Staphylococcus aureus cvfB gene. Infect Immun (2007) 0.94
Two-component signaling in the virulence of Staphylococcus aureus: a silkworm larvae-pathogenic agent infection model of virulence. Methods Enzymol (2007) 0.93
Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite. Mol Biochem Parasitol (2005) 0.93
A silkworm baculovirus model for assessing the therapeutic effects of antiviral compounds: characterization and application to the isolation of antivirals from traditional medicines. J Gen Virol (2008) 0.93
DnaB and DnaI temperature-sensitive mutants of Staphylococcus aureus: evidence for involvement of DnaB and DnaI in synchrony regulation of chromosome replication. Microbiology (2007) 0.92
An invertebrate hyperglycemic model for the identification of anti-diabetic drugs. PLoS One (2011) 0.92
Evaluation of Staphylococcus aureus virulence factors using a silkworm model. FEMS Microbiol Lett (2011) 0.92
Insect cytokine paralytic peptide (PP) induces cellular and humoral immune responses in the silkworm Bombyx mori. J Biol Chem (2010) 0.91
Inhibition of colony-spreading activity of Staphylococcus aureus by secretion of δ-hemolysin. J Biol Chem (2012) 0.90
Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence. J Immunol (2012) 0.89
Induction of apoptosis by depletion of DNA topoisomerase IIalpha in mammalian cells. Biochem Biophys Res Commun (2003) 0.89
Contribution of the mannan backbone of cryptococcal glucuronoxylomannan and a glycolytic enzyme of Staphylococcus aureus to contact-mediated killing of Cryptococcus neoformans. J Bacteriol (2007) 0.89
Silkworm apolipophorin protein inhibits Staphylococcus aureus virulence. J Biol Chem (2011) 0.89
Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. J Biol Chem (2002) 0.88
Novel RNA polymerase II mutation suppresses transcriptional fidelity and oxidative stress sensitivity in rpb9Delta yeast. Genes Cells (2010) 0.88
Digestion of extracellular DNA is required for giant colony formation of Staphylococcus aureus. Microb Pathog (2011) 0.88
FOXO1 and TCF7L2 genes involved in metastasis and poor prognosis in clear cell renal cell carcinoma. Genes Chromosomes Cancer (2010) 0.88
Identification of novel deoxyribofuranosyl indole antimicrobial agents. J Antibiot (Tokyo) (2011) 0.88
Distribution of Kakugo virus and its effects on the gene expression profile in the brain of the worker honeybee Apis mellifera L. J Virol (2009) 0.87
Effects of molecular mass and hydrophobicity on transport rates through non-specific pathways of the silkworm larva midgut. Int J Antimicrob Agents (2005) 0.87
Use of silkworm larvae to study pathogenic bacterial toxins. J Biochem (2006) 0.87
Induction of virulence gene expression in Staphylococcus aureus by pulmonary surfactant. Infect Immun (2014) 0.87
Transcriptional repression of the IMD2 gene mediated by the transcriptional co-activator Sub1. Genes Cells (2008) 0.87
Independent recognition of Staphylococcus aureus by two receptors for phagocytosis in Drosophila. J Biol Chem (2012) 0.87
CvfA protein and polynucleotide phosphorylase act in an opposing manner to regulate Staphylococcus aureus virulence. J Biol Chem (2014) 0.86
Porphyromonas gingivalis peptidoglycans induce excessive activation of the innate immune system in silkworm larvae. J Biol Chem (2010) 0.86
Inhibitory role for D-alanylation of wall teichoic acid in activation of insect Toll pathway by peptidoglycan of Staphylococcus aureus. J Immunol (2010) 0.85
In vitro and in vivo anti-MRSA activities of nosokomycins. Drug Discov Ther (2014) 0.84
Apoptosis-inducing activity of compounds screened and characterized from cinobufacini by bioassay-guided isolation. Mol Med Rep (2011) 0.84
Acute oral toxicity test of chemical compounds in silkworms. Drug Discov Ther (2016) 0.83
Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources. BMC Pharmacol (2010) 0.83
Serratia marcescens induces apoptotic cell death in host immune cells via a lipopolysaccharide- and flagella-dependent mechanism. J Biol Chem (2012) 0.83
p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis. FEBS Lett (2011) 0.83
Isolation of a temperature-sensitive dnaA mutant of Staphylococcus aureus. FEMS Microbiol Lett (2006) 0.83
Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. J Biol Chem (2010) 0.83
Auxiliary role for D-alanylated wall teichoic acid in Toll-like receptor 2-mediated survival of Staphylococcus aureus in macrophages. Immunology (2009) 0.83
Direct interaction between metastasis-associated protein 1 and endophilin 3. FEBS Lett (2005) 0.83
Insect cytokine paralytic peptide activates innate immunity via nitric oxide production in the silkworm Bombyx mori. Dev Comp Immunol (2012) 0.82
Shuttle vectors derived from pN315 for study of essential genes in Staphylococcus aureus. Biol Pharm Bull (2010) 0.82
Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module. Structure (2010) 0.82
Serratia marcescens suppresses host cellular immunity via the production of an adhesion-inhibitory factor against immunosurveillance cells. J Biol Chem (2014) 0.82
GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1. Genes Cells (2004) 0.81
Lipopolysaccharide O-antigen of enterohemorrhagic Escherichia coli O157:H7 is required for killing both insects and mammals. FEMS Microbiol Lett (2012) 0.81
Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph. BMC Pharmacol Toxicol (2012) 0.81
Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II. J Biochem (2003) 0.80
Isolation of temperature-sensitive mutations in murC of Staphylococcus aureus. FEMS Microbiol Lett (2007) 0.80
Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation. Genes Cells (2009) 0.80
Silkworm apolipophorin protein inhibits hemolysin gene expression of Staphylococcus aureus via binding to cell surface lipoteichoic acids. J Biol Chem (2013) 0.80
Antibiotic-producing bacteria from stag beetle mycangia. Drug Discov Ther (2015) 0.80
Myogenic differentiation of Drosophila Schneider cells by DNA double-strand break-inducing drugs. Differentiation (2003) 0.80
Glycophorin A requirement for expression of O-linked antigens on the erythrocyte membrane. Genes Cells (2003) 0.80
Prevention of death in bacterium-infected mice by a synthetic antimicrobial peptide, L5, through activation of host immunity. Antimicrob Agents Chemother (2009) 0.80
Isolation and characterization of temperature-sensitive mutants of the Staphylococcus aureus dnaC gene. FEMS Microbiol Lett (2002) 0.79
Total synthesis and biological evaluation of the antibiotic lysocin E and its enantiomeric, epimeric, and N-demethylated analogues. Angew Chem Int Ed Engl (2014) 0.79
Lactic acid bacteria activating innate immunity improve survival in bacterial infection model of silkworm. Drug Discov Ther (2016) 0.79
Duffy antigen is important for the lethal effect of the lethal strain of Plasmodium yoelii 17XL. Parasitol Res (2004) 0.79
Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus. J Biol Chem (2005) 0.79
Binding between azurocidin and calreticulin: its involvement in the activation of peripheral monocytes. J Biochem (2004) 0.79
Rapid exchange of bound ADP on the Staphylococcus aureus replication initiation protein DnaA. J Biol Chem (2009) 0.79
Identification of novel members of the Xenopus Ca2+ -dependent lectin family and analysis of their gene expression during tail regeneration and development. J Biochem (2007) 0.79
Embryonic lethality of mutant mice deficient in the p116 gene. J Biochem (2002) 0.79
Cloning and expression of a novel sulfotransferase with unique substrate specificity from Bombyx mori. Biosci Biotechnol Biochem (2007) 0.79
Glycophorin A-knockout mice, which lost sialoglycoproteins from the red blood cell membrane, are resistant to lethal infection of Babesia rodhaini. Vet Parasitol (2007) 0.79
Paralytic peptide: an insect cytokine that mediates innate immunity. Arch Insect Biochem Physiol (2015) 0.79