Published in Mod Rheumatol on September 25, 2008
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum (1998) 8.69
Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum (1997) 5.57
Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group. N Engl J Med (2000) 4.76
Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group. N Engl J Med (1992) 2.62
A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate. Arthritis Rheum (2004) 1.71
Anti-interleukin 6 receptor antibody treatment in rheumatic disease. Ann Rheum Dis (2000) 1.56
Randomized, placebo-controlled, crossover trial of low-dose oral methotrexate in children with extended oligoarticular or systemic arthritis. Arthritis Rheum (2000) 1.55
Methotrexate in juvenile idiopathic arthritis: answers and questions. J Rheumatol (2000) 1.51
Methotrexate-nonsteroidal antiinflammatory drug interaction in children with arthritis. J Rheumatol (1990) 1.48
Can food influence the absorption of methotrexate in children with acute lymphoblastic leukaemia? Lancet (1980) 1.46
Pharmacokinetics of oral methotrexate in children. Cancer Res (1983) 1.24
Leflunomide or methotrexate for juvenile rheumatoid arthritis. N Engl J Med (2005) 1.22
A nationwide surveillance study of rheumatic diseases among Japanese children. Acta Paediatr Jpn (1997) 1.15
Performance of the preliminary definition of improvement in juvenile chronic arthritis patients treated with methotrexate. Italian Pediatric Rheumatology Study Group. Ann Rheum Dis (1998) 1.12
Hepatitis B vaccination in children with juvenile idiopathic arthritis. Ann Rheum Dis (2004) 1.07
Use of methotrexate in juvenile idiopathic arthritis. Arch Dis Child (2003) 1.07
Toxicity and serum levels of methotrexate in children with juvenile rheumatoid arthritis. Arthritis Rheum (1989) 1.03
The effects of daily intake of folic acid on the efficacy of methotrexate therapy in children with juvenile rheumatoid arthritis. A controlled study. J Rheumatol (1997) 0.98
Standard methodology for Segment I, II, and III Pediatric Rheumatology Collaborative Study Group studies. I. Design. J Rheumatol (1982) 0.94
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis. Semin Arthritis Rheum (1993) 0.91
Plasma levels after oral methotrexate in children with juvenile rheumatoid arthritis. J Rheumatol (1993) 0.88
Methotrexate in juvenile rheumatoid arthritis. Evidence of age dependent pharmacokinetics. Eur J Clin Pharmacol (1995) 0.81
Outcomes research in the therapeutic use of methotrexate in children with chronic peripheral arthritis. J Pediatr (1998) 0.78
Influence of food on the bioavailability of oral methotrexate in children. J Rheumatol (1995) 0.78
Methotrexate for treating juvenile idiopathic arthritis. Cochrane Database Syst Rev (2001) 0.78
The use of non-steroidal anti-inflammatory drugs in paediatric rheumatic diseases. Br J Rheumatol (1993) 0.78
[Recent topics on rheumatism and collagen diseases in childhood]. Nihon Naika Gakkai Zasshi (2007) 0.78
[A survey of the doses of methotrexate and salazosulfapyridine in Japanese patients with rheumatoid arthritis]. Ryumachi (2002) 0.77
[Pharmacokinetics of methotrexate in rheumatoid arthritis: therapeutic implications]. Therapie (1997) 0.77
Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum (2005) 2.64
Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients. Blood (2007) 1.69
Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection. Am J Hematol (2005) 1.65
High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative Study. Arthritis Rheum (2011) 1.61
Henoch-Schonlein purpura presenting duodenal involvement similar to superior mesenteric artery syndrome in a girl. Eur J Pediatr (2006) 1.51
Urinary beta 2-microglobulin in premature infants with chorioamnionitis and chronic lung disease. J Pediatr (2003) 1.44
Intravenous gamma globulin for thrombotic microangiopathy of unknown etiology. Pediatr Nephrol (2006) 1.43
Superior mesenteric artery syndrome: risk factor for duodenal involvement in Henoch-Schönlein purpura. Pediatr Int (2011) 1.39
Prognostic factors for chronic active Epstein-Barr virus infection. J Infect Dis (2003) 1.36
Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. J Clin Invest (2006) 1.29
Postmarketing surveillance of tocilizumab for rheumatoid arthritis in Japan: interim analysis of 3881 patients. Ann Rheum Dis (2011) 1.27
Assessment of damage in juvenile-onset systemic lupus erythematosus: a multicenter cohort study. Arthritis Rheum (2003) 1.26
Efficacy and limitation of infliximab treatment for children with Kawasaki disease intractable to intravenous immunoglobulin therapy: report of an open-label case series. J Rheumatol (2012) 1.20
Milk fat globule EGF factor 8 in the serum of human patients of systemic lupus erythematosus. J Leukoc Biol (2008) 1.13
Health-related quality of life in juvenile-onset systemic lupus erythematosus and its relationship to disease activity and damage. Arthritis Rheum (2004) 1.10
Norovirus-associated encephalopathy. Pediatr Infect Dis J (2006) 1.08
Multiple transcripts of Ca2+ channel alpha1-subunits and a novel spliced variant of the alpha1C-subunit in rat ductus arteriosus. Am J Physiol Heart Circ Physiol (2005) 1.07
Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: comment on the article by Kawashima et al. Arthritis Rheum (2002) 1.03
Safety and effectiveness of adalimumab in Japanese rheumatoid arthritis patients: postmarketing surveillance report of 7740 patients. Mod Rheumatol (2013) 1.03
Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101. J Virol (2010) 0.99
Tocilizumab masks the clinical symptoms of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: the diagnostic significance of interleukin-18 and interleukin-6. Cytokine (2012) 0.99
Efficacy of plasma exchange therapy for Kawasaki disease intractable to intravenous gamma-globulin. Mod Rheumatol (2004) 0.98
T-type Ca2+ channels promote oxygenation-induced closure of the rat ductus arteriosus not only by vasoconstriction but also by neointima formation. J Biol Chem (2009) 0.98
Safety and response to influenza vaccine in patients with systemic-onset juvenile idiopathic arthritis receiving tocilizumab. Mod Rheumatol (2012) 0.98
CD14 -550 C/T, which is related to the serum level of soluble CD14, is associated with the development of respiratory syncytial virus bronchiolitis in the Japanese population. J Infect Dis (2007) 0.97
A CpG-containing oligodeoxynucleotide as an efficient adjuvant counterbalancing the Th1/Th2 immune response in diphtheria-tetanus-pertussis vaccine. Vaccine (2005) 0.96
Maternal antibody against toxic shock syndrome toxin-1 may protect infants younger than 6 months of age from developing Kawasaki syndrome. J Infect Dis (2002) 0.96
Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial disease. Hum Mutat (2012) 0.93
Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritis. Mod Rheumatol (2011) 0.93
Down-regulation of CXCR4 expression on human CD8+ T cells during peripheral differentiation. Eur J Immunol (2004) 0.93
Safety and efficacy of canakinumab in Japanese patients with phenotypes of cryopyrin-associated periodic syndrome as established in the first open-label, phase-3 pivotal study (24-week results). Clin Exp Rheumatol (2013) 0.92
Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan. Clin Rheumatol (2012) 0.92
Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis. Br J Clin Pharmacol (2011) 0.91
Effectiveness and safety of tocilizumab: postmarketing surveillance of 7901 patients with rheumatoid arthritis in Japan. J Rheumatol (2013) 0.91
Increased interleukin-18 expression in bone marrow of a patient with systemic juvenile idiopathic arthritis and unrecognized macrophage-activation syndrome. Arthritis Rheum (2004) 0.90
Analysis of gender differences in genetic risk: association of TNFAIP3 polymorphism with male childhood-onset systemic lupus erythematosus in the Japanese population. PLoS One (2013) 0.89
A molecular epidemiological study of respiratory viruses detected in Japanese children with acute wheezing illness. BMC Infect Dis (2011) 0.89
Graft versus leukemia effect against juvenile myelomonocytic leukemia after unrelated cord blood transplantation. Pediatr Blood Cancer (2008) 0.89
N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species. Int J Hematol (2003) 0.89
Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma. Int Arch Allergy Immunol (2006) 0.88
Functional and phenotypic analysis of human memory CD8+ T cells expressing CXCR3. J Leukoc Biol (2006) 0.88
Host-specific adaptation of HIV-1 subtype B in the Japanese population. J Virol (2014) 0.88
Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Arthritis Rheumatol (2014) 0.87
Clinical features of Mycoplasma pneumoniae infections in the 2010 epidemic season: report of two cases with unusual presentations. Pediatr Neonatol (2013) 0.87
Frequent somatic mosaicism of NEMO in T cells of patients with X-linked anhidrotic ectodermal dysplasia with immunodeficiency. Blood (2012) 0.87
De novo duplication of 17p13.1-p13.2 in a patient with intellectual disability and obesity. Am J Med Genet A (2014) 0.87
Nationwide survey of severe respiratory syncytial virus infection in children who do not meet indications for palivizumab in Japan. J Infect Chemother (2010) 0.87
Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis. Nephrol Dial Transplant (2010) 0.87
Clinical study of tocilizumab in children with systemic-onset juvenile idiopathic arthritis. Clin Rev Allergy Immunol (2005) 0.87
Interleukin-6, interleukin-8, and soluble tumor necrosis factor receptor-I in the cord blood as predictors of chronic lung disease in premature infants. Am J Obstet Gynecol (2004) 0.86
Clinical analysis of 50 children with juvenile dermatomyositis. Mod Rheumatol (2012) 0.86
alpha-Tocopherol transfer protein expression in rat liver exposed to hyperoxia. Free Radic Res (2002) 0.86
Household transmission of Streptococcus pneumoniae among siblings with acute otitis media. J Clin Microbiol (2002) 0.86
Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. PLoS One (2012) 0.86
A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population. Arthritis Res Ther (2006) 0.86
Influence of CYP3A5 and ABCB1 gene polymorphisms on calcineurin inhibitor-related neurotoxicity after hematopoietic stem cell transplantation. Clin Transplant (2010) 0.86
Human parechovirus-3 infection in nine neonates and infants presenting symptoms of hemophagocytic lymphohistiocytosis. J Infect Chemother (2012) 0.86
Cytokine biomarker candidates in breast milk associated with the development of atopic dermatitis in 6-month-old infants. Int Arch Allergy Immunol (2012) 0.85
Effect of anakinra on arthropathy in CINCA/NOMID syndrome. Pediatr Rheumatol Online J (2010) 0.85
Flow cytometric chemosensitivity assay using JC‑1, a sensor of mitochondrial transmembrane potential, in acute leukemia. Cancer Chemother Pharmacol (2013) 0.84
Pharmacokinetics, efficacy, and safety of short-term (12 weeks) etanercept for methotrexate-refractory polyarticular juvenile idiopathic arthritis in Japan. Mod Rheumatol (2005) 0.84
IL-10 gene polymorphism, but not TGF-beta1 gene polymorphisms, is associated with food allergy in a Japanese population. Pediatr Allergy Immunol (2008) 0.84
Hyperzincemia with systemic inflammation: a heritable disorder of calprotectin metabolism with rheumatic manifestations? J Pediatr (2002) 0.84
Severity of chorioamnionitis and neonatal outcome. J Obstet Gynaecol Res (2011) 0.84
Four cases of arthritis associated with Mycoplasma pneumoniae infection. Pediatr Int (2008) 0.84
Mizoribine as an effective combined maintenance therapy with prednisolone in child-onset systemic lupus erythematosus. Pediatr Int (2002) 0.83
[Gastrointestinal involvement and renal infarction in a boy with classic polyarteritis nodosa diagnosed with 3D-computed tomography angiography]. Nihon Rinsho Meneki Gakkai Kaishi (2008) 0.83
Long-term treatment of systemic juvenile idiopathic arthritis with tocilizumab: results of an open-label extension study in Japan. Ann Rheum Dis (2012) 0.83
Analysis of cases of severe respiratory failure in children with influenza (H1N1) 2009 infection in Japan. J Infect Chemother (2011) 0.83
Proposal for juvenile idiopathic arthritis guidance on diagnosis and treatment for primary care pediatricians and nonpediatric rheumatologists (2007). Mod Rheumatol (2007) 0.83
A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study. Rheumatology (Oxford) (2013) 0.83
Possible relationship between streptococcal pyrogenic exotoxin A and Kawasaki syndrome in patients older than six months of age. Pediatr Infect Dis J (2003) 0.83