Filter preconditioning enables representative scaled-down modelling of filter capacity and viral clearance by mitigating the impact of virus spike impurities.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 2782314)

Published in Biotechnol Appl Biochem on April 01, 2009

Authors

Navid Z Khan1, Joseph J Parrella, Paul W Genest, Michael S Colman

Author Affiliations

1: Bioprocess R&D, Virology Group, Millipore Corporation, 80 Ashby Road, Bedford, MA 01730, USA.

Articles citing this

Porcine parvovirus removal using trimer and biased hexamer peptides. Biotechnol J (2011) 0.75

Articles cited by this

Mammalian cells in culture frequently release type C viruses. Science (1973) 1.79

Points to consider in the manufacture and testing of monoclonal antibody products for human use (1997). U.S. Food and Drug Administration Center for Biologics Evaluation and Research. J Immunother (1997) 1.50

Recent studies on retrovirus-like particles in Chinese hamster ovary cells. Dev Biol Stand (1992) 0.92

Experience with viral contamination in cell culture. Dev Biol Stand (1996) 0.92

Phage passage after extended processing in small-virus-retentive filters. Biotechnol Appl Biochem (2007) 0.90

Real time quantitative PCR as a method to evaluate xenotropic murine leukemia virus removal during pharmaceutical protein purification. Biotechnol Bioeng (2004) 0.88

Normal-flow virus filtration: detection and assessment of the endpoint in bio-processing. Biotechnol Appl Biochem (2005) 0.88

Raw materials as a source of contamination in large-scale cell culture. Dev Biol Stand (1998) 0.87

Application of bacteriophages as surrogates for mammalian viruses: a case for use in filter validation based on precedents and current practices in medical and environmental virology. PDA J Pharm Sci Technol (2000) 0.85

Chinese hamster ovary cells contain transcriptionally active full-length type C proviruses. J Virol (1994) 0.83

Increasing the capacity of parvovirus-retentive membranes: performance of the Viresolve Prefilter. Biotechnol Appl Biochem (2006) 0.82

Use of bacteriophages as surrogates for mammalian viruses. Dev Biol (Basel) (2004) 0.80