M Thomas Record

Author PubWeight™ 61.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Novel computer program for fast exact calculation of accessible and molecular surface areas and average surface curvature. J Comput Chem 2002 3.00
2 Mechanism of bacterial transcription initiation: RNA polymerase - promoter binding, isomerization to initiation-competent open complexes, and initiation of RNA synthesis. J Mol Biol 2011 2.50
3 Crowding and confinement effects on protein diffusion in vivo. J Bacteriol 2006 1.84
4 Kinetic studies and structural models of the association of E. coli sigma(70) RNA polymerase with the lambdaP(R) promoter: large scale conformational changes in forming the kinetically significant intermediates. J Mol Biol 2002 1.83
5 Hofmeister salt effects on surface tension arise from partitioning of anions and cations between bulk water and the air-water interface. J Phys Chem B 2007 1.77
6 The exclusion of glycine betaine from anionic biopolymer surface: why glycine betaine is an effective osmoprotectant but also a compatible solute. Biochemistry 2004 1.52
7 Thermodynamic origin of hofmeister ion effects. J Phys Chem B 2008 1.50
8 Roles of cytoplasmic osmolytes, water, and crowding in the response of Escherichia coli to osmotic stress: biophysical basis of osmoprotection by glycine betaine. Biochemistry 2003 1.48
9 Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A 2007 1.44
10 Protein surface salt bridges and paths for DNA wrapping. Curr Opin Struct Biol 2002 1.37
11 Cytoplasmic protein mobility in osmotically stressed Escherichia coli. J Bacteriol 2008 1.34
12 Preferential interactions of glycine betaine and of urea with DNA: implications for DNA hydration and for effects of these solutes on DNA stability. Biochemistry 2004 1.31
13 Use of urea and glycine betaine to quantify coupled folding and probe the burial of DNA phosphates in lac repressor-lac operator binding. Biochemistry 2005 1.31
14 Protein diffusion in the periplasm of E. coli under osmotic stress. Biophys J 2011 1.30
15 Why Hofmeister effects of many salts favor protein folding but not DNA helix formation. Proc Natl Acad Sci U S A 2010 1.30
16 Interactions of the osmolyte glycine betaine with molecular surfaces in water: thermodynamics, structural interpretation, and prediction of m-values. Biochemistry 2009 1.29
17 Quantifying why urea is a protein denaturant, whereas glycine betaine is a protein stabilizer. Proc Natl Acad Sci U S A 2011 1.27
18 Separation of preferential interaction and excluded volume effects on DNA duplex and hairpin stability. Proc Natl Acad Sci U S A 2011 1.26
19 Partitioning of atmospherically relevant ions between bulk water and the water/vapor interface. Proc Natl Acad Sci U S A 2006 1.23
20 The effects of upstream DNA on open complex formation by Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A 2004 1.22
21 Solute probes of conformational changes in open complex (RPo) formation by Escherichia coli RNA polymerase at the lambdaPR promoter: evidence for unmasking of the active site in the isomerization step and for large-scale coupled folding in the subsequent conversion to RPo. Biochemistry 2006 1.22
22 Late steps in the formation of E. coli RNA polymerase-lambda P R promoter open complexes: characterization of conformational changes by rapid [perturbant] upshift experiments. J Mol Biol 2007 1.18
23 Evidence for a tyrosine-adenine stacking interaction and for a short-lived open intermediate subsequent to initial binding of Escherichia coli RNA polymerase to promoter DNA. J Mol Biol 2008 1.17
24 Urea-amide preferential interactions in water: quantitative comparison of model compound data with biopolymer results using water accessible surface areas. J Phys Chem B 2007 1.16
25 Large changes in cytoplasmic biopolymer concentration with osmolality indicate that macromolecular crowding may regulate protein-DNA interactions and growth rate in osmotically stressed Escherichia coli K-12. J Mol Recognit 2004 1.16
26 Thermal and urea-induced unfolding of the marginally stable lac repressor DNA-binding domain: a model system for analysis of solute effects on protein processes. Biochemistry 2003 1.15
27 Application of the local-bulk partitioning and competitive binding models to interpret preferential interactions of glycine betaine and urea with protein surface. Biochemistry 2004 1.11
28 Effect of the number of nucleic acid oligomer charges on the salt dependence of stability (DeltaG 37degrees) and melting temperature (Tm): NLPB analysis of experimental data. Biochemistry 2004 1.10
29 Generalized derivation of an exact relationship linking different coefficients that characterize thermodynamic effects of preferential interactions. Biophys Chem 2002 1.08
30 Probing DNA binding, DNA opening, and assembly of a downstream clamp/jaw in Escherichia coli RNA polymerase-lambdaP(R) promoter complexes using salt and the physiological anion glutamate. Biochemistry 2010 1.07
31 One-step DNA melting in the RNA polymerase cleft opens the initiation bubble to form an unstable open complex. Proc Natl Acad Sci U S A 2010 1.05
32 Formation of a wrapped DNA-protein interface: experimental characterization and analysis of the large contributions of ions and water to the thermodynamics of binding IHF to H' DNA. J Mol Biol 2007 1.04
33 Methods of changing biopolymer volume fraction and cytoplasmic solute concentrations for in vivo biophysical studies. Methods Enzymol 2007 1.00
34 Probing the protein-folding mechanism using denaturant and temperature effects on rate constants. Proc Natl Acad Sci U S A 2013 0.98
35 Interactions of the KWK6 cationic peptide with short nucleic acid oligomers: demonstration of large Coulombic end effects on binding at 0.1-0.2 M salt. Nucleic Acids Res 2004 0.96
36 DNA binding mode transitions of Escherichia coli HU(alphabeta): evidence for formation of a bent DNA--protein complex on intact, linear duplex DNA. J Mol Biol 2008 0.95
37 Thermodynamics and folding pathway of tetraloop receptor-mediated RNA helical packing. J Mol Biol 2008 0.91
38 Key roles of the downstream mobile jaw of Escherichia coli RNA polymerase in transcription initiation. Biochemistry 2012 0.90
39 Preferential interactions in aqueous solutions of urea and KCl. Biophys Chem 2003 0.90
40 Gibbs-Duhem-based relationships among derivatives expressing the concentration dependences of selected chemical potentials for a multicomponent system. Biophys Chem 2004 0.89
41 Quantifying functional group interactions that determine urea effects on nucleic acid helix formation. J Am Chem Soc 2013 0.89
42 Quantifying additive interactions of the osmolyte proline with individual functional groups of proteins: comparisons with urea and glycine betaine, interpretation of m-values. Biochemistry 2013 0.87
43 Interactions of cationic ligands and proteins with small nucleic acids: analytic treatment of the large coulombic end effect on binding free energy as a function of salt concentration. Biochemistry 2006 0.86
44 Using surface tension data to predict differences in surface and bulk concentrations of nonelectrolytes in water. J Phys Chem C Nanomater Interfaces 2009 0.84
45 Nonspecific DNA binding and bending by HUαβ: interfaces of the three binding modes characterized by salt-dependent thermodynamics. J Mol Biol 2011 0.83
46 Quantifying the roles of water and solutes (denaturants, osmolytes, and Hofmeister salts) in protein and model processes using the solute partitioning model. Methods Mol Biol 2009 0.83
47 Asymptotic solution of the cylindrical nonlinear Poisson-Boltzmann equation at low salt concentration: analytic expressions for surface potential and preferential interaction coefficient. Proc Natl Acad Sci U S A 2002 0.82
48 Positioning the Intracellular Salt Potassium Glutamate in the Hofmeister Series by Chemical Unfolding Studies of NTL9. Biochemistry 2016 0.80
49 Correction to "quantifying functional group interactions that determine urea effects on nucleic Acid helix formation". J Am Chem Soc 2013 0.78
50 Using solutes and kinetics to probe large conformational changes in the steps of transcription initiation. Methods Mol Biol 2015 0.78
51 Rapid quench mixing to quantify kinetics of steps in association of Escherichia coli RNA polymerase with promoter DNA. Methods Enzymol 2003 0.77
52 Contributions of the histidine side chain and the N-terminal alpha-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH. Biochemistry 2010 0.76