Published in Methods on October 09, 2008
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Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca(2+) sensor to canine cardiomyocytes. J Biomed Biotechnol (2009) 0.89
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Detection of differentially regulated subsarcolemmal calcium signals activated by vasoactive agonists in rat pulmonary artery smooth muscle cells. Am J Physiol Cell Physiol (2013) 0.84
Mitochondrial matrix Ca²⁺ accumulation regulates cytosolic NAD⁺/NADH metabolism, protein acetylation, and sirtuin expression. Mol Cell Biol (2014) 0.83
The future of immunoimaging--deeper, bigger, more precise, and definitively more colorful. Eur J Immunol (2013) 0.82
Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging. Nat Methods (2015) 0.81
Novel full-spectral flow cytometry with multiple spectrally-adjacent fluorescent proteins and fluorochromes and visualization of in vivo cellular movement. Cytometry A (2015) 0.79
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Real-time imaging of Ca(2+) mobilization and degranulation in mast cells. Methods Mol Biol (2015) 0.75
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Use of genetically-encoded calcium indicators for live cell calcium imaging and localization in virus-infected cells. Methods (2015) 0.75
Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. Sci Rep (2015) 0.75
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Circularly permuted green fluorescent proteins engineered to sense Ca2+. Proc Natl Acad Sci U S A (2001) 6.63
Dynamic and quantitative Ca2+ measurements using improved cameleons. Proc Natl Acad Sci U S A (1999) 6.63
Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins. Proc Natl Acad Sci U S A (2004) 6.33
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2. Proc Natl Acad Sci U S A (2006) 4.71
Ca2+ indicators based on computationally redesigned calmodulin-peptide pairs. Chem Biol (2006) 4.52
Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci U S A (2004) 4.46
Genetically encoded indicators of cellular calcium dynamics based on troponin C and green fluorescent protein. J Biol Chem (2004) 2.34
Stable interactions between mitochondria and endoplasmic reticulum allow rapid accumulation of calcium in a subpopulation of mitochondria. J Biol Chem (2003) 2.28
A FRET-based calcium biosensor with fast signal kinetics and high fluorescence change. Biophys J (2005) 2.02
Genetically encoded bright Ca2+ probe applicable for dynamic Ca2+ imaging of dendritic spines. Anal Chem (2005) 1.91
Single fluorescent protein-based Ca2+ sensors with increased dynamic range. BMC Biotechnol (2007) 1.79
Improved calcium imaging in transgenic mice expressing a troponin C-based biosensor. Nat Methods (2007) 1.75
Biosensors for the detection of calcium and pH. Methods Cell Biol (2007) 1.68
FRET-based in vivo Ca2+ imaging by a new calmodulin-GFP fusion molecule. Nat Struct Biol (2001) 1.45
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Developing sensors for real-time measurement of high Ca2+ concentrations. Biochemistry (2007) 1.14
Targeting recombinant aequorin to specific intracellular organelles. Methods Cell Biol (1994) 1.07
Live-cell transforms between Ca2+ transients and FRET responses for a troponin-C-based Ca2+ sensor. Biophys J (2007) 0.95
Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments. Methods Enzymol (2000) 0.89
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol (2004) 36.25
A monomeric red fluorescent protein. Proc Natl Acad Sci U S A (2002) 21.56
MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature (2010) 4.88
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor. Nat Methods (2008) 2.44
Genetically encoded sensors to elucidate spatial distribution of cellular zinc. J Biol Chem (2009) 1.80
Fluorescent sensors for measuring metal ions in living systems. Chem Rev (2014) 1.71
Measuring steady-state and dynamic endoplasmic reticulum and Golgi Zn2+ with genetically encoded sensors. Proc Natl Acad Sci U S A (2011) 1.68
Fluorescent biosensors of protein function. Curr Opin Chem Biol (2008) 1.60
Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis. Nat Chem Biol (2010) 1.26
BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins. J Biol Chem (2008) 1.19
Analysis of red-fluorescent proteins provides insight into dark-state conversion and photodegradation. Biophys J (2011) 1.18
Imaging type-III secretion reveals dynamics and spatial segregation of Salmonella effectors. Nat Methods (2010) 1.18
Spectroscopic and electronic structure studies of the trinuclear Cu cluster active site of the multicopper oxidase laccase: nature of its coordination unsaturation. J Am Chem Soc (2005) 1.16
Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes. Biochim Biophys Acta (2012) 1.10
Contributions of intracellular compartments to calcium dynamics: implicating an acidic store. Traffic (2006) 1.09
Direct comparison of a genetically encoded sensor and small molecule indicator: implications for quantification of cytosolic Zn(2+). ACS Chem Biol (2013) 1.06
Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction. Proc Natl Acad Sci U S A (2012) 1.03
New sensors for quantitative measurement of mitochondrial Zn(2+). ACS Chem Biol (2012) 1.01
Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome. Proc Natl Acad Sci U S A (2012) 0.98
Quantification of real-time Salmonella effector type III secretion kinetics reveals differential secretion rates for SopE2 and SptP. Chem Biol (2008) 0.97
New alternately colored FRET sensors for simultaneous monitoring of Zn²⁺ in multiple cellular locations. PLoS One (2012) 0.95
Atypical mitochondrial fission upon bacterial infection. Proc Natl Acad Sci U S A (2013) 0.95
Microfluidic cell counter with embedded optical fibers fabricated by femtosecond laser ablation and anodic bonding. Opt Express (2009) 0.92
Using a genetically targeted sensor to investigate the role of presenilin-1 in ER Ca2+ levels and dynamics. Mol Biosyst (2010) 0.89
Microfluidic flow cytometer for quantifying photobleaching of fluorescent proteins in cells. Anal Chem (2012) 0.85
Differential effects of procaspase-3 activating compounds in the induction of cancer cell death. Mol Pharm (2012) 0.84
FACS-based selection of tandem tetracysteine peptides with improved ReAsH brightness in live cells. Chembiochem (2010) 0.84
Examples of high-frequency EPR studies in bioinorganic chemistry. J Biol Inorg Chem (2002) 0.83
Microfluidic cell sorter for use in developing red fluorescent proteins with improved photostability. Lab Chip (2013) 0.81
High-throughput examination of fluorescence resonance energy transfer-detected metal-ion response in mammalian cells. J Am Chem Soc (2012) 0.80
Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching. Integr Biol (Camb) (2015) 0.77
Quantitative measurement of Ca2+ and Zn2+ in mammalian cells using genetically encoded fluorescent biosensors. Methods Mol Biol (2014) 0.77
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