Simon Schenk

Author PubWeight™ 44.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 2007 10.21
2 A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 2008 4.43
3 Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metab 2009 3.10
4 SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. Mol Cell Biol 2008 2.73
5 SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. Am J Physiol Endocrinol Metab 2009 2.25
6 Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise. J Biol Chem 2011 1.47
7 Commentaries on viewpoint: does SIRT1 determine exercise-induced skeletal muscle mitochondrial biogenesis: differences between in vitro and in vivo experiments? J Appl Physiol (1985) 2012 1.43
8 Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance. Diabetes 2012 1.38
9 Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes. Am J Physiol Endocrinol Metab 2009 1.19
10 A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab 2010 1.10
11 NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise. Am J Physiol Endocrinol Metab 2012 1.05
12 Inducible nitric oxide synthase deficiency in myeloid cells does not prevent diet-induced insulin resistance. Mol Endocrinol 2010 1.02
13 Effects of dietary carbohydrate restriction with high protein intake on protein metabolism and the somatotropic axis. J Clin Endocrinol Metab 2005 1.01
14 G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. J Clin Invest 2012 0.97
15 A novel pathway of insulin sensitivity in chromogranin A null mice: a crucial role for pancreastatin in glucose homeostasis. J Biol Chem 2009 0.96
16 Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice. Diabetes 2012 0.93
17 Energy deficit after exercise augments lipid mobilization but does not contribute to the exercise-induced increase in insulin sensitivity. J Appl Physiol (1985) 2009 0.92
18 Alterations in carbohydrate metabolism in response to short-term dietary carbohydrate restriction. Am J Physiol Endocrinol Metab 2005 0.91
19 High-fat diet elevates resting intramuscular triglyceride concentration and whole body lipolysis during exercise. Am J Physiol Endocrinol Metab 2003 0.89
20 Application of the [γ-32P] ATP kinase assay to study anabolic signaling in human skeletal muscle. J Appl Physiol (1985) 2014 0.88
21 Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res 2012 0.88
22 The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes. Am J Physiol Regul Integr Comp Physiol 2011 0.87
23 Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators. J Med Chem 2009 0.86
24 High fatty acid availability after exercise alters the regulation of muscle lipid metabolism. Metabolism 2010 0.84
25 Unraveling the complexities of SIRT1-mediated mitochondrial regulation in skeletal muscle. Exerc Sport Sci Rev 2013 0.81
26 Role of the cytoskeleton in muscle transcriptional responses to altered use. Physiol Genomics 2013 0.78
27 Manipulation of dietary carbohydrate and muscle glycogen affects glucose uptake during exercise when fat oxidation is impaired by beta-adrenergic blockade. Am J Physiol Endocrinol Metab 2004 0.76
28 Histological Evidence of Muscle Degeneration in Advanced Human Rotator Cuff Disease. J Bone Joint Surg Am 2017 0.75
29 New opportunities and novel paradigms to support neuromuscular research. Phys Med Rehabil Clin N Am 2012 0.75
30 Interaction between lipid availability,endurance exercise and insulin sensitivity. Med Sport Sci 2014 0.75