Ken Shortman

Author PubWeight™ 130.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nomenclature of monocytes and dendritic cells in blood. Blood 2010 6.63
2 Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming. Immunity 2006 5.32
3 Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo. Nat Immunol 2007 5.20
4 Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes. Nat Immunol 2006 4.53
5 Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells. Nat Immunol 2009 4.51
6 Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proc Natl Acad Sci U S A 2004 3.61
7 Cutting edge: generation of splenic CD8+ and CD8- dendritic cell equivalents in Fms-like tyrosine kinase 3 ligand bone marrow cultures. J Immunol 2005 3.47
8 The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture. Proc Natl Acad Sci U S A 2006 3.19
9 Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood 2002 3.19
10 Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus. J Exp Med 2002 2.94
11 The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J Exp Med 2002 2.93
12 Cutting edge: conventional CD8 alpha+ dendritic cells are generally involved in priming CTL immunity to viruses. J Immunol 2004 2.87
13 The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement. Blood 2008 2.83
14 Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells. Nat Immunol 2008 2.44
15 Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets. Blood 2002 2.30
16 Dendritic cells in the thymus contribute to T-regulatory cell induction. Proc Natl Acad Sci U S A 2008 2.26
17 Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC. J Exp Med 2010 2.26
18 CD8alpha+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo. J Immunol 2005 2.16
19 Most lymphoid organ dendritic cell types are phenotypically and functionally immature. Blood 2003 2.05
20 CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen. J Exp Med 2011 1.95
21 The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity 2012 1.89
22 Heterogeneity of thymic dendritic cells. Semin Immunol 2005 1.81
23 The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells. J Immunol 2003 1.79
24 Skin-derived dendritic cells can mediate deletional tolerance of class I-restricted self-reactive T cells. J Immunol 2007 1.75
25 Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors. Blood 2002 1.68
26 Development of the dendritic cell system during mouse ontogeny. J Immunol 2004 1.68
27 Cutting edge: conventional CD8 alpha+ dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-1. J Immunol 2003 1.63
28 Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte colony-stimulating factor, and pegylated granulocyte-macrophage colony-stimulating factor on dendritic cell subsets in mice. Blood 2002 1.62
29 Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells. Blood 2006 1.54
30 Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol 2011 1.54
31 Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery. Blood 2004 1.54
32 Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells. J Exp Med 2007 1.49
33 Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function. Mol Cell Biol 2005 1.45
34 Found in translation: the human equivalent of mouse CD8+ dendritic cells. J Exp Med 2010 1.45
35 Enhancing immune responses by targeting antigen to DC. Eur J Immunol 2009 1.43
36 Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells. J Immunol 2006 1.37
37 Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype. J Immunol 2011 1.33
38 Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli. Blood 2003 1.32
39 DEC-205 is a cell surface receptor for CpG oligonucleotides. Proc Natl Acad Sci U S A 2012 1.29
40 The acquisition of antigen cross-presentation function by newly formed dendritic cells. J Immunol 2011 1.29
41 The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. J Immunol 2009 1.25
42 Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger". Eur J Immunol 2005 1.23
43 Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling. Immunol Cell Biol 2007 1.21
44 Distinct roles for the NF-kappaB1 and c-Rel transcription factors in the differentiation and survival of plasmacytoid and conventional dendritic cells activated by TLR-9 signals. Blood 2005 1.17
45 Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development. Int Immunol 2005 1.15
46 Development of antigen cross-presentation capacity in dendritic cells. Trends Immunol 2012 1.08
47 Highlights of 10 years of immunology in Nature Reviews Immunology. Nat Rev Immunol 2011 1.06
48 IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation. J Immunol 2002 1.06
49 IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells. Int Immunol 2002 1.06
50 Differential production of inflammatory chemokines by murine dendritic cell subsets. Immunobiology 2004 1.04
51 Boosting antibody responses by targeting antigens to dendritic cells. Trends Immunol 2011 1.03
52 Dendritic cell populations in Leishmania major-infected skin and draining lymph nodes. Infect Immun 2004 1.02
53 Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells. Blood 2012 1.02
54 Hierarchy of susceptibility of dendritic cell subsets to infection by Leishmania major: inverse relationship to interleukin-12 production. Infect Immun 2002 1.02
55 CD36 is differentially expressed by CD8+ splenic dendritic cells but is not required for cross-presentation in vivo. J Immunol 2002 0.99
56 Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN. Int Immunol 2006 0.97
57 Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo. PLoS One 2011 0.97
58 Factors determining the spontaneous activation of splenic dendritic cells in culture. Innate Immun 2010 0.95
59 GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis. J Immunol 2014 0.94
60 CD8alpha+ mouse spleen dendritic cells do not originate from the CD8alpha- dendritic cell subset. Blood 2003 0.92
61 Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3(-/-) mice. Mol Immunol 2011 0.91
62 Is it a DC, is it an NK? No, it's an IKDC. Nat Med 2006 0.89
63 Dendritic cells from mice neonatally vaccinated with modified vaccinia virus Ankara transfer resistance against herpes simplex virus type I to naive one-week-old mice. J Immunol 2004 0.89
64 Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells. J Immunol 2003 0.89
65 FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo. J Immunol 2014 0.88
66 Treatment of neonatal mice with Flt3 ligand leads to changes in dendritic cell subpopulations associated with enhanced IL-12 and IFN-alpha production. Eur J Immunol 2004 0.88
67 The protease inhibitor cystatin C is differentially expressed among dendritic cell populations, but does not control antigen presentation. J Immunol 2003 0.87
68 The isolation and identification of murine dendritic cell populations from lymphoid tissues and their production in culture. Methods Mol Biol 2008 0.87
69 Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates. Eur J Immunol 2015 0.87
70 Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice. Eur J Immunol 2002 0.86
71 Thymic but not splenic CD8⁺ DCs can efficiently cross-prime T cells in the absence of licensing factors. Eur J Immunol 2011 0.85
72 Evolution of B cell responses to Clec9A-targeted antigen. J Immunol 2013 0.84
73 Switching from a restricted to an effective CD4 T cell response by activating CD8+ murine dendritic cells with a Toll-like receptor 9 ligand. Eur J Immunol 2005 0.84
74 The proliferative response of CD4 T cells to steady-state CD8+ dendritic cells is restricted by post-activation death. Int Immunol 2006 0.83
75 Regeneration of dendritic cells in aged mice. Cell Mol Immunol 2010 0.81
76 Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE. DNA Seq 2006 0.80
77 Are dendritic cells end cells? Nat Immunol 2004 0.78
78 The remembrance of 56 years of research. Immunol Cell Biol 2012 0.75
79 Professor Donald Metcalf (1929–2014). Immunity 2015 0.75