Published in Br J Cancer on October 21, 2008
miR-506 regulates epithelial mesenchymal transition in breast cancer cell lines. PLoS One (2013) 1.31
Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells. Clin Exp Metastasis (2011) 1.00
HGF-induced PKCζ activation increases functional CXCR4 expression in human breast cancer cells. PLoS One (2012) 0.89
CXCR4 in breast cancer: oncogenic role and therapeutic targeting. Drug Des Devel Ther (2015) 0.84
HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epithelial transition in bone metastatic versus parental breast carcinoma cells. Mol Cancer (2015) 0.80
Cancer and the chemokine network. Nat Rev Cancer (2004) 10.27
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet (1999) 9.53
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J Biol Chem (1990) 9.21
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol (2003) 7.89
Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science (2001) 6.79
A renaissance for SRC. Nat Rev Cancer (2004) 6.27
Metastasis: a question of life or death. Nat Rev Cancer (2006) 6.26
What's up and down with histone deacetylation and transcription? Cell (1997) 5.99
Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev (2007) 4.46
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol (2000) 4.30
c-Src and cooperating partners in human cancer. Cancer Cell (2004) 4.22
IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy. J Clin Invest (2005) 4.07
The Akt/PKB pathway: molecular target for cancer drug discovery. Oncogene (2005) 3.42
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J (2004) 2.94
The biology of the Ets1 proto-oncogene. Mol Cancer (2003) 2.88
Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK. J Immunol (2005) 2.81
The role of histone deacetylases (HDACs) in human cancer. Mol Oncol (2007) 2.72
HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination. Oncogene (2007) 2.67
Silencing of CXCR4 blocks breast cancer metastasis. Cancer Res (2005) 2.59
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res (2004) 2.31
"The stress of dying": the role of heat shock proteins in the regulation of apoptosis. J Cell Sci (2004) 2.29
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. Clin Cancer Res (2001) 2.15
Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes. J Biol Chem (2005) 2.06
The MET receptor tyrosine kinase in invasion and metastasis. J Cell Physiol (2007) 2.02
Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades. J Biol Chem (2003) 1.97
Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration. Cancer Res (2006) 1.96
Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene (2004) 1.83
The Met pathway: master switch and drug target in cancer progression. FASEB J (2006) 1.74
Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J Biol Chem (2003) 1.73
Chemokines in tumor angiogenesis and metastasis. Cancer Metastasis Rev (2007) 1.63
HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells. J Cell Biol (2006) 1.62
MSK activation and physiological roles. Front Biosci (2008) 1.62
Potential role of a novel transcriptional coactivator PELP1 in histone H1 displacement in cancer cells. Cancer Res (2004) 1.59
Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter. J Biol Chem (2005) 1.57
Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions. Int J Cancer (2006) 1.48
Distinct mechanisms of tumor invasion and metastasis. Trends Mol Med (2007) 1.48
Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes. Hepatology (2007) 1.47
HGF induces CXCR4 and CXCL12-mediated tumor invasion through Ets1 and NF-kappaB. Carcinogenesis (2006) 1.40
3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth. J Med Chem (2000) 1.38
HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene (2005) 1.37
Histone deacetylase inhibitors: gathering pace. Curr Opin Pharmacol (2006) 1.31
Epigenetic aberrations and cancer. Mol Cancer (2006) 1.29
A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells. Clin Cancer Res (2003) 1.23
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. J Biol Chem (2002) 1.20
Retracted Estradiol rapidly activates Akt via the ErbB2 signaling pathway. Mol Endocrinol (2003) 1.19
Depletion of mutant p53 and cytotoxicity of histone deacetylase inhibitors. Cancer Res (2005) 1.16
Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: potential regulation by ligand-dependent degradation and HIF-1alpha. Biochem Biophys Res Commun (2006) 1.15
Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression. J Immunol (2003) 1.14
Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding. Mol Cancer Res (2005) 1.13
NF-kappa B inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen. Ann Oncol (2004) 1.08
Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression. Cancer (2007) 1.08
Involvement of an autocrine stromal cell derived factor-1/CXCR4 system on the distant metastasis of human oral squamous cell carcinoma. Mol Cancer Res (2007) 1.01
Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas. Oncogene (2006) 0.99
Caspase-3 status is a determinant of the differential responses to genistein between MDA-MB-231 and MCF-7 breast cancer cells. Biochim Biophys Acta (2007) 0.97
Hepatocyte growth factor in invasive growth of carcinomas. Cell Mol Life Sci (2007) 0.95
Normal breast epithelial cells induce apoptosis of breast cancer cells via Fas signaling. Exp Cell Res (2002) 0.94
Hepatocyte growth factor enhances CXCR4 expression favoring breast cancer cell invasiveness. Exp Cell Res (2005) 0.93
Regulation of the INK4a/ARF locus by histone deacetylase inhibitors. J Biol Chem (2005) 0.92
c-Src/histone deacetylase 3 interaction is crucial for hepatocyte growth factor dependent decrease of CXCR4 expression in highly invasive breast tumor cells. Mol Cancer Res (2007) 0.88
Inhibition of tumor-stromal interaction through HGF/Met signaling by valproic acid. Biochem Biophys Res Commun (2007) 0.87
SRC proximal and core promoter elements dictate TAF1 dependence and transcriptional repression by histone deacetylase inhibitors. Mol Cell Biol (2004) 0.86
Hepatocyte growth factor signal coupling to various transcription factors depends on triggering of Met receptor and protein kinase transducers in human hepatoma cells HepG2. Exp Cell Res (2000) 0.81
Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment. J Cell Physiol (2008) 0.81
Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression. Oncogene (2006) 0.79
Microalbuminuria and endothelial dysfunction in essential hypertension. Lancet (1994) 1.94
Hepatocyte growth factor-activated NF-kappaB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines. Carcinogenesis (2004) 1.20
Increased echodensity of myocardial wall in the diabetic heart: an ultrasound tissue characterization study. J Am Coll Cardiol (1995) 1.16
Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells. Carcinogenesis (2001) 1.11
d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties. Proc Natl Acad Sci U S A (1995) 1.07
The MAP kinase cascades are activated during post-ischemic liver reperfusion. FEBS Lett (1996) 1.02
Is polyamine decrease a common feature of apoptosis? Evidence from gamma rays- and heat shock-induced cell death. Biochem Biophys Res Commun (1995) 0.98
Induction of diamine oxidase activity in rat kidney during compensatory hypertrophy. Biochim Biophys Acta (1982) 0.91
Age-dependent increase of collagenase expression can be reduced by alpha-tocopherol via protein kinase C inhibition. Free Radic Biol Med (1999) 0.91
Cell cycle phase perturbations and apoptosis in tumour cells induced by aplidine. Br J Cancer (2002) 0.91
Diamine oxidase activity induction in regenerating rat liver. Biochim Biophys Acta (1982) 0.90
State-resolved reactivity of CH4(2nu3) on Pt(111) and Ni(111): effects of barrier height and transition state location. J Phys Chem A (2007) 0.87
Leptin activates Stat3, Stat1 and AP-1 in mouse adipose tissue. Mol Cell Endocrinol (2000) 0.84
Hepatocyte growth factor induces pro-apoptotic genes in HepG2 hepatoma but not in B16-F1 melanoma cells. J Cell Physiol (2001) 0.84
The role of inflammation and infection in prostate cancer: Importance in prevention, diagnosis and treatment. Drugs Today (Barc) (2010) 0.83
Diamine oxidase activity in regenerating rat liver and in 4-dimethylaminoazobenzene-induced and Yoshida AH 130 hepatomas. Cancer Res (1981) 0.82
Hepatocyte growth factor differently influences Met-E-cadherin phosphorylation and downstream signaling pathway in two models of breast cells. Cell Mol Life Sci (2006) 0.82
Rapid stimulation of mitogen-activated protein kinase of rat liver by prolactin. Biochem J (1994) 0.82
Hepatocyte growth factor signal coupling to various transcription factors depends on triggering of Met receptor and protein kinase transducers in human hepatoma cells HepG2. Exp Cell Res (2000) 0.81
Evaluation of venous flow by light reflection rheography (LRR) in athletes performing track race. J Sports Med Phys Fitness (1991) 0.81
Hyperthermia induces gene expression of heat shock protein 70 and phosphorylation of mitogen activated protein kinases in the rat cerebellum. Neurosci Lett (2001) 0.80
[Ultrasonic tissue characterization analysis in type 1 diabetes: a very early index of diabetic cardiomyopathy?]. G Ital Cardiol (1998) 0.80
Signal transduction pathway of prolactin in rat liver. Mol Cell Endocrinol (1997) 0.79
Influence of proteasome and redox state on heat shock-induced activation of stress kinases, AP-1 and HSF. Biochim Biophys Acta (2001) 0.79
Oxidative stress in families of type 1 diabetic patients: further evidence. Diabetes Care (2001) 0.79
The potentiation of the response to blunt cardiac trauma by ethanol in dogs. J Trauma (1986) 0.79
Alterations in lymphocyte subsets as prognosticators of postoperative infections. Eur J Surg (1995) 0.79
Inhibitory effect of prepro-thyrotrophin-releasing hormone (178-199) on adrenocorticotrophic hormone secretion by human corticotroph tumours. J Neuroendocrinol (2010) 0.78
The liver response to in vivo heat shock involves the activation of MAP kinases and RAF and the tyrosine phosphorylation of Shc proteins. Biochem Biophys Res Commun (1995) 0.78
Combined oral contraceptives: health benefits beyond contraception. Panminerva Med (2014) 0.78
Can insulin action induce myocardial texture alterations in essential hypertension? Am J Hypertens (1999) 0.78
Regulation of diamine oxidase expression by beta 2-adrenoceptors in normal and hypertrophic rat kidney. Biochim Biophys Acta (1985) 0.78
Ultrasonic videodensitometric analysis in type 1 diabetic myocardium. Coron Artery Dis (1996) 0.78
Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. Biochim Biophys Acta (1983) 0.77
Effects of acute, oral ethanol on cardiovascular performance before and after experimental blunt cardiac trauma. J Trauma (1987) 0.77
Stimulation of hepatic and renal diamine oxidase activity after acute ethanol administration. Biochim Biophys Acta (1984) 0.77
Polyamines and diamine oxidase activity in maternal, embryonal, and fetal tissues of rat after chronic ethanol consumption. Biochem Biophys Res Commun (1987) 0.77
Inhibition of proteasome function prevents thymocyte apoptosis: involvement of ornithine decarboxylase. Biochem Biophys Res Commun (1998) 0.77
Ethanol and polyamine metabolism in adult and fetal tissues: possible implication in fetus damage. Adv Alcohol Subst Abuse (1987) 0.77
Splanchnic vascular effects of pharmacologic doses of oxytocin in the canine. Proc Soc Exp Biol Med (1981) 0.77
Response of tissue diamine oxidase activity to polyamine administration. Biochem J (1986) 0.76
RRR-alpha-tocopherol regulation of gene transcription in response to the cell oxidant status. Z Ernahrungswiss (1998) 0.76
Plasma galanin concentrations in obese, normal weight and anorectic women. Int J Obes Relat Metab Disord (1995) 0.76
About CD26 CD8 lymphocytes in type 1 diabetes mellitus. Scand J Immunol (2010) 0.76
Fertility preservation in female cancer patients: an emerging challenge for physicians. Panminerva Med (2014) 0.76
Relation of fetal growth to maternal responses to oral glucose tolerance test throughout gestation. Acta Diabetol (1999) 0.76
Cerebrospinal fluid and plasma concentrations of SRIH, beta-endorphin, CRH, NPY and GHRH in obese and normal weight subjects. Int J Obes Relat Metab Disord (1995) 0.76
A 29-year-old woman with complex atypical hyperplasia and polycystic ovary syndrome: a challenging issue. Eur J Gynaecol Oncol (2014) 0.75
Diagnosis of coronary artery disease by radionuclide ventriculography during stress: handgrip and cold pressor. Acta Cardiol (1985) 0.75
Estrogenic regulation of diamine oxidase activity in rat uterus. Agents Actions (1990) 0.75
Microalbuminuria and erythrocyte sodium-hydrogen exchange in essential hypertension. Hypertension (1995) 0.75
Alpha-adrenergic blocking agents and the cardiovascular response to pharmacological doses of vasopressin. Pharmacology (1980) 0.75
[Preparation of a standard for the hemocromocytometric autoanalyzer (author's transl)]. Quad Sclavo Diagn (1978) 0.75
[Accuracy of radioisotopic ventriculography with Au-195m]. Cardiologia (1986) 0.75
The reliability of urinary albumin assay by immunonephelometry in the clinical practice. The critical role of medical surveillance on laboratory routine. Acta Diabetol (1997) 0.75
Celiac disease and endometriosis: an insidious and worrisome association hard to diagnose: a case report. Clin Exp Obstet Gynecol (2014) 0.75
Imipenem/cilastatin reduces cyclosporin-induced tubular damage in kidney transplant recipients. Transplant Proc (1998) 0.75
Spores of lichen-forming fungi in the mycoaerosol and their relationships with climate factors. Sci Total Environ (2013) 0.75
[Study of the diastolic phase with a radioisotopic method in coronary disease]. Cardiologia (1985) 0.75
Phosphorylation pattern of liver proteins during the early stages of the acute-phase response. Cell Biol Int (1993) 0.75
Gestational diabetes mellitus (GDM) and macrosomia: a controversial story. Ann Ist Super Sanita (1997) 0.75
[Cardiovascular stimulation tests in the evaluation of autonomic neuropathy]. Cardiologia (1988) 0.75
Hemodynamic changes in global and regional left ventricular function induced by nitroglycerin. An assessment with 195mAu radionuclide ventriculography. J Nucl Med Allied Sci (1987) 0.75
Estrogenic control of spermidine/spermine N1-acetyltransferase activity in rat uterus. Adv Exp Med Biol (1988) 0.75
Reproducibility and reliability of first pass radionuclide ventriculography with Au-195m. Validation of Au-195m radionuclide ventriculography. Acta Cardiol (1987) 0.75
Protein kinase C and gene expression in prolactin-stimulated postischemic livers. Ann N Y Acad Sci (1994) 0.75
[Ultrasonic evaluation of early atherosclerotic damage in patients with type 1 diabetes mellitus]. Minerva Cardioangiol (1995) 0.75
Erythrocyte sodium/hydrogen exchange activity and albuminuria in type 1 diabetic families. Diabetes Care (2000) 0.75
Erythrocyte sodium-hydrogen exchange and microalbuminuria in type I diabetes. Diabetes Care (1996) 0.75
Expression of a growth arrest specific gene (gas-6) during liver regeneration: molecular mechanisms and signalling pathways. J Cell Physiol (1994) 0.75
Diamine oxidase activity in a model of multistep hepatocarcinogenesis. Cancer Lett (1990) 0.75
Effect of acute ethanol administration on diamine oxidase activity in maternal, embryonal and fetal tissues. Agents Actions (1987) 0.75
Demonstration of beta 1-adrenergic receptors in human placenta by (-)[125I]iodocyanopindolol binding. J Nucl Med Allied Sci (1989) 0.75
Erythrocyte Na+/H+ exchange and preclinical abnormalities of the left ventricular diastolic function in normotensive type 1 (insulin-dependent) diabetic patients. Acta Diabetol (1997) 0.75