Ki-Up Lee

Author PubWeight™ 100.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med 2004 2.80
2 Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Nat Neurosci 2006 2.36
3 AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1. Biochem Biophys Res Commun 2005 2.10
4 Prevalence of angiographically defined obstructive coronary artery disease in asymptomatic patients with type 2 diabetes according to the coronary calcium score. Intern Med 2012 2.02
5 Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo. Circ Res 2002 1.87
6 Activation of NAD(P)H:quinone oxidoreductase 1 prevents arterial restenosis by suppressing vascular smooth muscle cell proliferation. Circ Res 2009 1.75
7 Hypothalamic Angptl4/Fiaf is a novel regulator of food intake and body weight. Diabetes 2010 1.61
8 Essential role of mitochondrial function in adiponectin synthesis in adipocytes. Diabetes 2007 1.55
9 Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. Am J Physiol Endocrinol Metab 2009 1.39
10 Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin. Obesity (Silver Spring) 2009 1.34
11 Association of elevated serum ferritin concentration with insulin resistance and impaired glucose metabolism in Korean men and women. Metabolism 2010 1.30
12 Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance. PLoS One 2009 1.27
13 Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. Hepatology 2008 1.27
14 Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation. J Bone Miner Res 2006 1.26
15 Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells. Antioxid Redox Signal 2007 1.21
16 Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner. Endocrinology 2008 1.18
17 Effects of alpha-lipoic Acid on body weight in obese subjects. Am J Med 2011 1.15
18 Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase. Arterioscler Thromb Vasc Biol 2005 1.11
19 Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation. Diabetes 2003 1.10
20 Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders. Diabetes 2011 1.09
21 Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Biochem Biophys Res Commun 2005 1.08
22 Hormonal activity of AIMP1/p43 for glucose homeostasis. Proc Natl Acad Sci U S A 2006 1.08
23 alpha-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. J Allergy Clin Immunol 2004 1.06
24 Glucotoxicity in the INS-1 rat insulinoma cell line is mediated by the orphan nuclear receptor small heterodimer partner. Diabetes 2007 1.05
25 Relationship between serum free T4 (FT4) levels and metabolic syndrome (MS) and its components in healthy euthyroid subjects. Clin Endocrinol (Oxf) 2008 1.05
26 Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases cAMP-stimulated hepatic gluconeogenesis via inhibition of CREB. Endocrinology 2009 1.05
27 α-Lipoic acid prevents neointimal hyperplasia via induction of p38 mitogen-activated protein kinase/Nur77-mediated apoptosis of vascular smooth muscle cells and accelerates postinjury reendothelialization. Arterioscler Thromb Vasc Biol 2010 1.05
28 Fetal and early postnatal protein malnutrition cause long-term changes in rat liver and muscle mitochondria. J Nutr 2003 1.04
29 AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts. Bone 2010 1.00
30 Alpha-lipoic acid inhibits TNF-alpha-induced apoptosis in human bone marrow stromal cells. J Bone Miner Res 2005 0.99
31 Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. Arterioscler Thromb Vasc Biol 2009 0.99
32 Effect of body weight and lifestyle changes on long-term course of nonalcoholic fatty liver disease in Koreans. Am J Med Sci 2009 0.99
33 Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity. Exp Mol Med 2007 0.97
34 Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells. Arterioscler Thromb Vasc Biol 2009 0.97
35 NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia. J Biol Chem 2010 0.96
36 Discordance between fasting glucose-based and hemoglobin A1c-based diagnosis of diabetes mellitus in Koreans. Diabetes Res Clin Pract 2011 0.96
37 alpha-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats. Biochem Biophys Res Commun 2005 0.96
38 Homocysteine enhances apoptosis in human bone marrow stromal cells. Bone 2006 0.95
39 Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner. J Lipid Res 2011 0.95
40 Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration. Arterioscler Thromb Vasc Biol 2004 0.95
41 Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients. Korean Diabetes J 2010 0.94
42 Estrogen receptor alpha gene polymorphisms Pvu II and Xba I influence association between leptin receptor gene polymorphism (Gln223Arg) and bone mineral density in young men. Eur J Endocrinol 2002 0.94
43 Association of serum gamma-glutamyltransferase and alanine aminotransferase activities with risk of type 2 diabetes mellitus independent of fatty liver. Diabetes Metab Res Rev 2009 0.93
44 Alpha-lipoic acid inhibits hepatic PAI-1 expression and fibrosis by inhibiting the TGF-beta signaling pathway. Biochem Biophys Res Commun 2010 0.92
45 Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002-2013: Nationwide population-based cohort study. Medicine (Baltimore) 2016 0.92
46 Circadian rhythm of serum vaspin in healthy male volunteers: relation to meals. J Clin Endocrinol Metab 2010 0.91
47 Lower waist-circumference cutoff point for the assessment of cardiometabolic risk in Koreans. Diabetes Res Clin Pract 2009 0.91
48 Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-κB pathways in monocytes/macrophages. J Leukoc Biol 2011 0.91
49 Obesity: the role of hypothalamic AMP-activated protein kinase in body weight regulation. Int J Biochem Cell Biol 2005 0.90
50 In vitro methylation of nuclear respiratory factor-1 binding site suppresses the promoter activity of mitochondrial transcription factor A. Biochem Biophys Res Commun 2004 0.90
51 Clusterin attenuates the development of renal fibrosis. J Am Soc Nephrol 2011 0.90
52 Cilostazol inhibits vascular smooth muscle cell growth by downregulation of the transcription factor E2F. Hypertension 2005 0.90
53 Effects of alpha-lipoic acid on the plasma levels of asymmetric dimethylarginine in diabetic end-stage renal disease patients on hemodialysis: a pilot study. Am J Nephrol 2007 0.89
54 eNOS plays a major role in adiponectin synthesis in adipocytes. Am J Physiol Endocrinol Metab 2010 0.89
55 Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice. Rheumatol Int 2006 0.88
56 Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2. Mol Cell Biol 2006 0.88
57 The prevalence of peripheral arterial disease in korean patients with type 2 diabetes mellitus attending a university hospital. Diabetes Metab J 2011 0.88
58 Elevated serum ceruloplasmin levels in subjects with metabolic syndrome: a population-based study. Metabolism 2002 0.86
59 Primary carcinoid tumor of the bilateral testis associated with carcinoid syndrome. Int J Urol 2004 0.86
60 The orphan nuclear receptor SHP attenuates renal fibrosis. J Am Soc Nephrol 2009 0.85
61 Dexamethasone regulates AP-1 to repress TNF-alpha induced MCP-1 production in human glomerular endothelial cells. Nephrol Dial Transplant 2004 0.85
62 Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes. Exp Mol Med 2012 0.85
63 Characterization of ASC-2 as an antiatherogenic transcriptional coactivator of liver X receptors in macrophages. Mol Endocrinol 2009 0.85
64 Glucocorticoid receptor mediated repression of human insulin gene expression is regulated by PGC-1alpha. Biochem Biophys Res Commun 2006 0.84
65 Heat shock protein 60 causes osteoclastic bone resorption via toll-like receptor-2 in estrogen deficiency. Bone 2009 0.84
66 Variable association between components of the metabolic syndrome and electrocardiographic abnormalities in Korean adults. Korean J Intern Med 2010 0.84
67 Intracellular fatty acid metabolism in skeletal muscle and insulin resistance. Curr Diabetes Rev 2005 0.83
68 Essential role of clusterin in pancreas regeneration. Dev Dyn 2011 0.83
69 A case of ACTH-producing pheochromocytoma associated with pregnancy. Endocr J 2003 0.82
70 Alpha-lipoic acid inhibits fractalkine expression and prevents neointimal hyperplasia after balloon injury in rat carotid artery. Atherosclerosis 2006 0.82
71 Adenine nucleotide translocator as a regulator of mitochondrial function: implication in the pathogenesis of metabolic syndrome. Korean Diabetes J 2010 0.82
72 Relationships between fasting plasma ghrelin levels and metabolic parameters in children and adolescents. Metabolism 2005 0.82
73 Increased circulating heat shock protein 60 induced by menopause, stimulates apoptosis of osteoblast-lineage cells via up-regulation of toll-like receptors. Bone 2009 0.82
74 Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor. J Clin Invest 2014 0.82
75 Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. Life Sci 2011 0.81
76 Forkhead transcription factor FoxO1 inhibits insulin- and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression. Biochem Biophys Res Commun 2009 0.81
77 Risk score model for the assessment of coronary artery disease in asymptomatic patients with type 2 diabetes. Medicine (Baltimore) 2015 0.81
78 S-adenosyl-L-methionine increases skeletal muscle mitochondrial DNA density and whole body insulin sensitivity in OLETF rats. J Nutr 2007 0.81
79 Regulation of mitochondrial transcription factor A expression by high glucose. Ann N Y Acad Sci 2004 0.81
80 The ascochlorin derivative, AS-6, inhibits TNF-alpha-induced adhesion molecule and chemokine expression in rat vascular smooth muscle cells. Life Sci 2006 0.80
81 Oleic acid induces endothelin-1 expression through activation of protein kinase C and NF-kappa B. Biochem Biophys Res Commun 2003 0.80
82 High glucose-induced NF-kappaB activation occurs via tyrosine phosphorylation of IkappaBalpha in human glomerular endothelial cells: involvement of Syk tyrosine kinase. Am J Physiol Renal Physiol 2008 0.80
83 Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease. Mol Cells 2011 0.80
84 Cilostazol inhibits high glucose- and angiotensin II-induced type 1 plasminogen activator inhibitor expression in artery wall and neointimal region after vascular injury. Atherosclerosis 2009 0.80
85 Lipolysis in skeletal muscle is decreased in high-fat-fed rats. Metabolism 2003 0.80
86 Thyroid transcription factor-1 regulates feeding behavior via melanocortin pathway in the hypothalamus. Diabetes 2011 0.79
87 Neuroendocrine phenotypes in a boy with 5q14 deletion syndrome implicate the regulatory roles of myocyte-specific enhancer factor 2C in the postnatal hypothalamus. Eur J Med Genet 2013 0.79
88 Orphan nuclear receptor small heterodimer partner inhibits angiotensin II- stimulated PAI-1 expression in vascular smooth muscle cells. Exp Mol Med 2010 0.79
89 Alpha-lipoic acid activates dimethylarginine dimethylaminohydrolase in cultured endothelial cells. Biochem Biophys Res Commun 2010 0.79
90 Nestin action during insulin-secreting cell differentiation. J Histochem Cytochem 2010 0.79
91 Nucleotide-binding oligomerization domain protein 2 deficiency enhances neointimal formation in response to vascular injury. Arterioscler Thromb Vasc Biol 2011 0.79
92 Homocysteine as a risk factor for development of microalbuminuria in type 2 diabetes. Korean Diabetes J 2010 0.78
93 Incidence of overt proteinuria and coronary artery disease in patients with type 2 diabetes mellitus: the role of microalbuminuria and retinopathy. Diabetes Res Clin Pract 2004 0.77
94 DHEA administration increases brown fat uncoupling protein 1 levels in obese OLETF rats. Biochem Biophys Res Commun 2003 0.77
95 Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by a novel compound, mercaptopyrazine, through suppression of nuclear factor-kappaB binding to DNA. Biochem Pharmacol 2004 0.77
96 Mitochondria and endoplasmic reticulum in diabetes and its complications. Exp Diabetes Res 2012 0.76
97 STAT1-independent down-regulation of interferon-gamma-induced class II transactivator and HLA-DR expression by transforming growth factor beta-1 in human glomerular endothelial cells. Nephron Exp Nephrol 2005 0.75
98 S-adenosyl methionine prevents endothelial dysfunction by inducing heme oxygenase-1 in vascular endothelial cells. Mol Cells 2013 0.75
99 Response: the prevalence of peripheral arterial disease in korean patients with type 2 diabetes mellitus attending a university hospital (diabetes metab j 2011;35:543-50). Diabetes Metab J 2012 0.75
100 Postmenopausal women lose less visceral adipose tissue during a weight reduction program. Menopause 2003 0.75
101 Response: Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients (Korean Diabetes J 2010;34:95-100). Korean Diabetes J 2010 0.75
102 Reply to the letter by S. Balta regarding "Patients should undergo conventional angiography to reveal any suspected coronary artery lesion". Intern Med 2013 0.75
103 Corrigendum: Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation. Sci Rep 2016 0.75
104 Improved efficacy of appetite suppression by lipoic acid particles prepared by nanocomminution. Drug Dev Ind Pharm 2009 0.75
105 Lipoic acid nanoparticles: effect of polymeric stabilizer on appetite suppression. Pharmazie 2010 0.75