Phosphorylation of tropomyosin extends cooperative binding of myosin beyond a single regulatory unit.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMC 2770177)

Published in Cell Motil Cytoskeleton on January 01, 2009

Authors

Vijay S Rao1, Ellisha N Marongelli, William H Guilford

Author Affiliations

1: Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22908, USA.

Articles citing this

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations. Circ Res (2013) 1.44

New insights into the regulation of the actin cytoskeleton by tropomyosin. Int Rev Cell Mol Biol (2010) 1.28

Increased phosphorylation of tropomyosin, troponin I, and myosin light chain-2 after stretch in rabbit ventricular myocardium under physiological conditions. J Mol Cell Cardiol (2010) 1.15

Recent insights into muscle fatigue at the cross-bridge level. Front Physiol (2012) 1.09

Direct regulation of striated muscle myosins by nitric oxide and endogenous nitrosothiols. PLoS One (2010) 0.99

Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation. Arch Biochem Biophys (2012) 0.90

Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. J Muscle Res Cell Motil (2011) 0.89

The role of tropomyosin isoforms and phosphorylation in force generation in thin-filament reconstituted bovine cardiac muscle fibres. J Muscle Res Cell Motil (2010) 0.84

Comparative biomechanics of thick filaments and thin filaments with functional consequences for muscle contraction. J Biomed Biotechnol (2010) 0.83

A study of tropomyosin's role in cardiac function and disease using thin-filament reconstituted myocardium. J Muscle Res Cell Motil (2013) 0.83

Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium. Arch Biochem Biophys (2012) 0.83

Force spectroscopy reveals multiple "closed states" of the muscle thin filament. J Biol Chem (2011) 0.82

Direct measurement of cortical force generation and polarization in a living parasite. Mol Biol Cell (2017) 0.79

A Spatially Detailed Model of Isometric Contraction Based on Competitive Binding of Troponin I Explains Cooperative Interactions between Tropomyosin and Crossbridges. PLoS Comput Biol (2015) 0.79

Loop 2 of myosin is a force-dependent inhibitor of the rigor bond. J Muscle Res Cell Motil (2014) 0.79

Muscle weakness in TPM3-myopathy is due to reduced Ca2+-sensitivity and impaired acto-myosin cross-bridge cycling in slow fibres. Hum Mol Genet (2015) 0.78

Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain. Arch Biochem Biophys (2015) 0.77

Modifications of myofilament protein phosphorylation and function in response to cardiac arrest induced in a swine model. Front Physiol (2015) 0.75

Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function. Mol Cell Neurosci (2017) 0.75

Articles cited by this

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res (2003) 15.74

Biological applications of optical forces. Annu Rev Biophys Biomol Struct (1994) 10.00

Purification of muscle actin. Methods Enzymol (1982) 9.11

Cooperation within actin filament in vertebrate skeletal muscle. Nat New Biol (1972) 7.00

Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament. Biophys J (1993) 5.66

Force measurements by micromanipulation of a single actin filament by glass needles. Nature (1988) 5.62

Tropomyosin coiled-coil interactions: evidence for an unstaggered structure. J Mol Biol (1975) 4.79

Cooperative binding of myosin subfragment-1 to the actin-troponin-tropomyosin complex. Proc Natl Acad Sci U S A (1980) 4.56

Relaxation of rabbit psoas muscle fibres from rigor by photochemical generation of adenosine-5'-triphosphate. J Physiol (1984) 3.85

Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin. J Mol Biol (1990) 3.80

Theoretical model for the cooperative equilibrium binding of myosin subfragment 1 to the actin-troponin-tropomyosin complex. Proc Natl Acad Sci U S A (1980) 3.72

Steric-model for activation of muscle thin filaments. J Mol Biol (1997) 3.70

Direct measurement of stiffness of single actin filaments with and without tropomyosin by in vitro nanomanipulation. Proc Natl Acad Sci U S A (1994) 3.65

The 14-fold periodicity in alpha-tropomyosin and the interaction with actin. J Mol Biol (1976) 3.23

Two-dimensional tracking of ncd motility by back focal plane interferometry. Biophys J (1998) 2.38

Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap. Biophys J (1997) 2.28

Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction. Proc Natl Acad Sci U S A (2006) 2.25

Preparation and identification of alpha- and beta-tropomyosins. Methods Enzymol (1982) 2.11

Dynamics of the muscle thin filament regulatory switch: the size of the cooperative unit. Biophys J (1994) 2.08

Actin filament mechanics in the laser trap. J Muscle Res Cell Motil (1997) 1.97

Cooperativity and switching within the three-state model of muscle regulation. Biochemistry (1999) 1.78

Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations. J Physiol (2002) 1.58

Cross-bridge interaction kinetics in rat myocardium are accelerated by strong binding of myosin to the thin filament. J Physiol (2001) 1.54

p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity. Circ Res (2007) 1.48

Sarcomeric dysfunction in heart failure. Cardiovasc Res (2007) 1.46

Calcium alone does not fully activate the thin filament for S1 binding to rigor myofibrils. Biophys J (1996) 1.44

In vitro motility analysis of actin-tropomyosin regulation by troponin and calcium. The thin filament is switched as a single cooperative unit. J Biol Chem (1995) 1.38

Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding. Biochemistry (2003) 1.38

Purification of cardiac myosin. Application to hypertrophied myocardium. Biochim Biophys Acta (1975) 1.37

Strong binding of myosin modulates length-dependent Ca2+ activation of rat ventricular myocytes. Circ Res (1998) 1.37

Regulation of force and unloaded sliding speed in single thin filaments: effects of regulatory proteins and calcium. J Physiol (2000) 1.31

Myosin binding-induced cooperative activation of the thin filament in cardiac myocytes and skeletal muscle fibers. Biophys J (1995) 1.27

Enhanced force generation by smooth muscle myosin in vitro. Proc Natl Acad Sci U S A (1994) 1.27

Specific phosphorylation at serine-283 of alpha tropomyosin from frog skeletal and rabbit skeletal and cardiac muscle. Proc Natl Acad Sci U S A (1978) 1.27

Analysis of troponin-tropomyosin binding to actin. Troponin does not promote interactions between tropomyosin molecules. J Biol Chem (1992) 1.22

Structure and interactions of the carboxyl terminus of striated muscle alpha-tropomyosin: it is important to be flexible. Biophys J (2002) 1.22

Dual requirement for flexibility and specificity for binding of the coiled-coil tropomyosin to its target, actin. Structure (2006) 1.21

Exchange of beta- for alpha-tropomyosin in hearts of transgenic mice induces changes in thin filament response to Ca2+, strong cross-bridge binding, and protein phosphorylation. J Biol Chem (1996) 1.17

Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin. Proc Natl Acad Sci U S A (2005) 1.16

Actin-tropomyosin activation of myosin subfragment 1 ATPase and thin filament cooperativity. The role of tropomyosin flexibility and end-to-end interactions. Biochemistry (1997) 1.16

The effect of mutations in alpha-tropomyosin (E40K and E54K) that cause familial dilated cardiomyopathy on the regulatory mechanism of cardiac muscle thin filaments. J Biol Chem (2007) 1.15

Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins. J Biol Chem (2007) 1.14

Different effects of cardiac versus skeletal muscle regulatory proteins on in vitro measures of actin filament speed and force. J Physiol (2005) 1.10

Modulation of actin mechanics by caldesmon and tropomyosin. Cell Motil Cytoskeleton (2008) 1.09

Effect of phosphorylation on the interaction and functional properties of rabbit striated muscle alpha alpha-tropomyosin. J Biol Chem (1989) 1.07

Tropomyosin directly modulates actomyosin mechanical performance at the level of a single actin filament. Proc Natl Acad Sci U S A (1999) 1.07

Bidirectional movement of actin filaments along tracks of myosin heads. Nature (1989) 1.07

The structure of the carboxyl terminus of striated alpha-tropomyosin in solution reveals an unusual parallel arrangement of interacting alpha-helices. Biochemistry (2003) 1.06

Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing. Mol Biol Cell (2003) 1.05

Comparison of the effects of smooth and skeletal tropomyosin on skeletal actomyosin subfragment 1 ATPase. J Biol Chem (1984) 1.04

Construction of an atomic model for tropomyosin and implications for interactions with actin. J Mol Biol (1986) 1.03

The essential role of tropomyosin in cooperative regulation of smooth muscle thin filament activity by caldesmon. J Biol Chem (1993) 1.00

Alternate model for the cooperative equilibrium binding of myosin subfragment-1-nucleotide complex to actin-troponin-tropomyosin. Proc Natl Acad Sci U S A (1983) 1.00

Skeletal regulatory proteins enhance thin filament sliding speed and force by skeletal HMM. J Muscle Res Cell Motil (2005) 1.00

The tail of myosin reduces actin filament velocity in the in vitro motility assay. Cell Motil Cytoskeleton (2004) 0.96

The effect of single residue substitutions of serine-283 on the strength of head-to-tail interaction and actin binding properties of rabbit skeletal muscle alpha-tropomyosin. J Biochem (2000) 0.94

Peroxynitrite inhibits myofibrillar protein function in an in vitro assay of motility. Free Radic Biol Med (2007) 0.94

Creating multiple time-shared laser traps with simultaneous displacement detection using digital signal processing hardware. Anal Biochem (2004) 0.93

Tropomyosin: regulator of actin filaments. Adv Exp Med Biol (2007) 0.92

Alterations to myofibrillar protein function in nonischemic regions of the heart early after myocardial infarction. Am J Physiol Heart Circ Physiol (2007) 0.90

The structural role of high molecular weight tropomyosins in dipteran indirect flight muscle and the effect of phosphorylation. J Muscle Res Cell Motil (2006) 0.87

Independent functions for the N- and C-termini in the overlap region of tropomyosin. Biochemistry (2000) 0.87

Phosphorylation of skeletal-muscle troponin I and troponin T by phospholipid-sensitive Ca2+-dependent protein kinase and its inhibition by troponin C and tropomyosin. Biochem J (1984) 0.86

Amino acid sequences of rabbit skeletal beta- and cardiac tropomyosins. FEBS Lett (1979) 0.86

Nuclear magnetic resonance evidence for the coexistence of several conformational states of rabbit cardiac and skeletal tropomyosins. Biochemistry (1980) 0.82

Light scattering in solutions of native and guanidinated rabbit tropomyosin. Biochim Biophys Acta (1960) 0.80

Analysis of cooperativity observed in pH titrations of proton nuclear magnetic resonances of histidine residues of rabbit cardiac tropomyosin. Biochemistry (1981) 0.79

Changes in end-to-end interactions of tropomyosin affect mouse cardiac muscle dynamics. Am J Physiol Heart Circ Physiol (2006) 0.79

Quantitative analysis of tropomyosin linear polymerization equilibrium as a function of ionic strength. J Biol Chem (2001) 0.79

Assignment and characterization of the histidine resonances in the 1H nuclear magnetic resonance spectra of rabbit tropomyosins. Biochemistry (1978) 0.79

Articles by these authors

Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction. Proc Natl Acad Sci U S A (2006) 2.25

The molecular mechanics of P- and L-selectin lectin domains binding to PSGL-1. Biophys J (2004) 1.42

The reciprocal coordination and mechanics of molecular motors in living cells. Proc Natl Acad Sci U S A (2009) 1.36

Direct regulation of striated muscle myosins by nitric oxide and endogenous nitrosothiols. PLoS One (2010) 0.99

The tail of myosin reduces actin filament velocity in the in vitro motility assay. Cell Motil Cytoskeleton (2004) 0.96

Enhancement of L-selectin, but not P-selectin, bond formation frequency by convective flow. Biophys J (2007) 0.94

Peroxynitrite inhibits myofibrillar protein function in an in vitro assay of motility. Free Radic Biol Med (2007) 0.94

Alterations to myofibrillar protein function in nonischemic regions of the heart early after myocardial infarction. Am J Physiol Heart Circ Physiol (2007) 0.90

The Effects of Load on E-Selectin Bond Rupture and Bond Formation. Cell Mol Bioeng (2010) 0.85

The viscoelastic properties of microvilli are dependent upon the cell-surface molecule. Biochem Biophys Res Commun (2010) 0.82

Force spectroscopy reveals multiple "closed states" of the muscle thin filament. J Biol Chem (2011) 0.82

Loop 2 of myosin is a force-dependent inhibitor of the rigor bond. J Muscle Res Cell Motil (2014) 0.79

Design, development, and evaluation of a novel retraction device for gallbladder extraction during laparoscopic cholecystectomy. J Gastrointest Surg (2013) 0.75