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1
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The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4.
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J Am Chem Soc
|
2004
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3.19
|
|
2
|
PRL phosphatases as potential molecular targets in cancer.
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Mol Cancer Ther
|
2005
|
1.67
|
|
3
|
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4.
|
Nucleic Acids Res
|
2007
|
1.66
|
|
4
|
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.
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J Am Chem Soc
|
2007
|
1.53
|
|
5
|
The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.
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Mol Cancer Ther
|
2008
|
1.44
|
|
6
|
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure.
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J Am Chem Soc
|
2005
|
1.40
|
|
7
|
Quinone electrophiles selectively adduct "electrophile binding motifs" within cytochrome c.
|
Biochemistry
|
2007
|
1.25
|
|
8
|
Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene.
|
Nucleic Acids Res
|
2008
|
1.16
|
|
9
|
Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.
|
J Biol Chem
|
2011
|
1.14
|
|
10
|
mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".
|
Biochimie
|
2010
|
1.07
|
|
11
|
The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure.
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J Am Chem Soc
|
2014
|
1.06
|
|
12
|
Tertiary DNA structure in the single-stranded hTERT promoter fragment unfolds and refolds by parallel pathways via cooperative or sequential events.
|
J Am Chem Soc
|
2012
|
1.02
|
|
13
|
Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?
|
ACS Chem Neurosci
|
2012
|
0.91
|
|
14
|
Redox-active magnetic resonance imaging contrast agents: studies with thiol-bearing 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetracetic acid derivatives.
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J Med Chem
|
2012
|
0.90
|
|
15
|
Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter.
|
J Med Chem
|
2012
|
0.89
|
|
16
|
Identification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers.
|
Invest New Drugs
|
2011
|
0.87
|
|
17
|
Regulation of the activity of the tumor suppressor PTEN by thioredoxin in Drosophila melanogaster.
|
Exp Cell Res
|
2007
|
0.86
|
|
18
|
Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging.
|
J Med Chem
|
2010
|
0.85
|
|
19
|
Synthesis and biological activity of 2-aminothiazoles as novel inhibitors of PGE2 production in cells.
|
Bioorg Med Chem Lett
|
2012
|
0.79
|
|
20
|
An N-ethyl-N-nitrosourea-induced mutation in N-acetyltransferase 1 in mice.
|
Biochem Biophys Res Commun
|
2008
|
0.78
|
|
21
|
Gaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay.
|
Top Curr Chem
|
2013
|
0.77
|
|
22
|
Application of a novel [3+2] cycloaddition reaction to prepare substituted imidazoles and their use in the design of potent DFG-out allosteric B-Raf inhibitors.
|
Bioorg Med Chem
|
2009
|
0.76
|
|
23
|
Psorospermin structural requirements for P-glycoprotein resistance reversal.
|
Mol Cancer Ther
|
2008
|
0.75
|
|
24
|
Synthesis and biological activity of aminophthalazines and aminopyridazines as novel inhibitors of PGE2 production in cells.
|
Bioorg Med Chem Lett
|
2012
|
0.75
|
|
25
|
Correction to "The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure".
|
J Am Chem Soc
|
2016
|
0.75
|