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1
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p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor.
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Mol Cell Biol
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1989
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3.62
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2
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Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.
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J Biol Chem
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1994
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3.46
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3
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Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin).
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Semin Oncol
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1999
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2.66
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4
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Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.
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J Clin Invest
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1993
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2.17
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5
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Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis.
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Proc Natl Acad Sci U S A
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1990
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1.99
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6
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Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor.
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J Immunol
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1993
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1.89
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7
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Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.
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Oncogene
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1994
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1.88
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8
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The autocrine production of transforming growth factor-beta 1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA.
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J Immunol
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1990
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1.83
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9
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Monoclonal antibody (B27M2) subdividing HLA-B27.
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Hum Immunol
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1982
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1.81
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10
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Humanization of an antibody directed against IgE.
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J Immunol
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1993
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1.64
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11
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Recombinant tumor necrosis factor causes activation of human granulocytes.
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Blood
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1987
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1.62
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12
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Monoclonal antibody therapy of human cancer: taking the HER2 protooncogene to the clinic.
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J Clin Immunol
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1991
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1.57
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13
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High resolution functional analysis of antibody-antigen interactions.
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J Mol Biol
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1992
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1.49
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14
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Expression of the p185 encoded by HER2 oncogene in normal and transformed human tissues.
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Int J Cancer
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1990
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1.36
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15
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Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.
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Proc Natl Acad Sci U S A
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1991
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1.29
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16
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Mammalian cell transient expression of tissue factor for the production of antigen.
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Protein Eng
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1990
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1.28
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17
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Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.
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Cancer Res
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1996
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1.25
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18
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Monoclonal anti-HLA-B27 antibody (B27M1): production and lack of detectable typing difference between patients with ankylosing spondylitis, Reiter's syndrome, and normal controls.
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Lancet
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1981
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1.25
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19
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A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells.
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Mol Cell Biol
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1993
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1.20
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20
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Evidence for an autocrine role of activin B within rat anterior pituitary cultures.
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Endocrinology
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1991
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1.19
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21
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Strain specificity and binding affinity requirements of neutralizing monoclonal antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1.
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J Virol
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1993
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1.16
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22
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Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth.
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Growth Regul
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1991
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1.13
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23
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Monoclonal antibodies to the extracellular domain of HIV-1IIIB gp160 that neutralize infectivity, block binding to CD4, and react with diverse isolates.
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AIDS Res Hum Retroviruses
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1992
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1.11
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24
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TGF-beta: a possible autocrine immune regulator.
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Ciba Found Symp
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1991
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1.09
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25
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Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation.
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J Biol Chem
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1992
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0.98
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26
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HLA-DR epitope region definition by use of monoclonal antibody probes.
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J Immunol
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1980
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0.95
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27
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Mutational analysis of thrombopoietin for identification of receptor and neutralizing antibody sites.
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J Biol Chem
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1997
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0.93
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28
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Identification of cysteine-rich domains of the type 1 tumor necrosis factor receptor involved in ligand binding.
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J Biol Chem
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1992
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0.93
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29
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Natriuretic peptide receptor-B (guanylyl cyclase-B) mediates C-type natriuretic peptide relaxation of precontracted rat aorta.
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J Biol Chem
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1995
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0.90
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30
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Human natriuretic peptide receptor-A guanylyl cyclase. Hormone cross-linking and antibody reactivity distinguish receptor glycoforms.
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J Biol Chem
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1992
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0.87
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31
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HER2 (c-erbB-2) oncoprotein expression in colorectal adenocarcinoma: an immunohistological study using three different antibodies.
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J Clin Pathol
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1992
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0.85
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32
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Development of herceptin.
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Breast Dis
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2000
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0.84
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33
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Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.
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Cancer Immunol Immunother
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1999
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0.84
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34
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Species-specific monoclonal antibody to a 43,000-molecular-weight membrane protein of Mycoplasma pneumoniae.
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J Clin Microbiol
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1986
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0.82
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35
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Novel non-isotopic method for the localization of receptors in tissue sections.
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J Histochem Cytochem
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2001
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0.82
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36
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Passive immunoneutralization with a monoclonal antibody reveals a role for endogenous activin-B in mediating FSH hypersecretion during estrus and following ovariectomy of hypophysectomized, pituitary-grafted rats.
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Endocrinology
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1992
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0.82
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37
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Increase in cyclic AMP levels by relaxin in newborn rhesus monkey uterus cell culture.
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In Vitro Cell Dev Biol
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1990
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0.81
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38
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Characterization of a recombinant extracellular domain of the type 1 tumor necrosis factor receptor: evidence for tumor necrosis factor-alpha induced receptor aggregation.
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Biochemistry
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1992
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0.81
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39
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Development of a specific and sensitive two-site enzyme-linked immunosorbent assay for measurement of inhibin-A in serum.
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Endocrinology
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1993
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0.80
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40
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Generation of antibodies and assays for transforming growth factor beta.
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Methods Enzymol
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1991
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0.80
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41
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Murine monoclonal antibodies defining neutralizing epitopes on tumor necrosis factor.
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Hybridoma
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1987
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0.78
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42
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Development and characterization of murine monoclonal antibodies to the latency-associated peptide of transforming growth factor beta 1.
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Hybridoma
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1995
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0.77
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43
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Characterization of murine monoclonal antibodies that recognize neutralizing epitopes on human C5a.
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Infect Immun
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1987
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0.75
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44
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A simplified new method for HLA-DR typing using the TM1 monoclonal antibody.
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Hum Immunol
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1983
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0.75
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45
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Activation of TNF-R1 receptor in the presence of copper kills TNF resistant CEM leukemic T cells.
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J Cell Physiol
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1994
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0.75
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