|
1
|
Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate.
|
Clin Cancer Res
|
2006
|
3.00
|
|
2
|
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations.
|
BMC Cancer
|
2014
|
1.79
|
|
3
|
Clear cell sarcoma-like tumor with osteoclast-like giant cells in the small bowel: further evidence for a new tumor entity.
|
Int J Surg Pathol
|
2005
|
1.74
|
|
4
|
Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations.
|
Lancet Oncol
|
2005
|
1.67
|
|
5
|
Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors.
|
Int J Cancer
|
2003
|
1.54
|
|
6
|
Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer.
|
Mod Pathol
|
2012
|
1.50
|
|
7
|
EGFR mutation detection in NSCLC--assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC.
|
Virchows Arch
|
2010
|
1.45
|
|
8
|
Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining.
|
J Pathol
|
2005
|
1.35
|
|
9
|
Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors.
|
J Mol Diagn
|
2004
|
1.33
|
|
10
|
Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis.
|
Gastroenterology
|
2005
|
1.32
|
|
11
|
Mutation analysis of gastrointestinal stromal tumors: increasing significance for risk assessment and effective targeted therapy.
|
Virchows Arch
|
2007
|
1.26
|
|
12
|
Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases.
|
Mod Pathol
|
2008
|
1.20
|
|
13
|
Multiple colon carcinomas in a patient with Cowden syndrome.
|
Int J Mol Med
|
2006
|
1.17
|
|
14
|
β-catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid-type fibromatosis.
|
Histopathology
|
2012
|
1.12
|
|
15
|
Distinct spatial expression patterns of AP-2alpha and AP-2gamma in non-neoplastic human breast and breast cancer.
|
Mod Pathol
|
2005
|
1.10
|
|
16
|
High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.
|
Arch Pathol Lab Med
|
2012
|
0.99
|
|
17
|
Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing.
|
Lung Cancer
|
2013
|
0.97
|
|
18
|
Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors.
|
Hum Pathol
|
2011
|
0.97
|
|
19
|
Optimal lymph node harvest in rectal cancer (UICC stages II and III) after preoperative 5-FU-based radiochemotherapy. Acetone compression is a new and highly efficient method.
|
Am J Surg Pathol
|
2012
|
0.96
|
|
20
|
Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling.
|
J Cancer Res Clin Oncol
|
2008
|
0.95
|
|
21
|
Kaposi's sarcoma of the gastrointestinal tract: report of two cases and review of the literature.
|
Pathol Res Pract
|
2007
|
0.95
|
|
22
|
Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization.
|
Histopathology
|
2012
|
0.93
|
|
23
|
A novel germline KIT mutation (p.L576P) in a family presenting with juvenile onset of multiple gastrointestinal stromal tumors, skin hyperpigmentations, and esophageal stenosis.
|
Am J Surg Pathol
|
2013
|
0.92
|
|
24
|
Pitfalls in the detection of t(11;22) translocation by fluorescence in situ hybridization and RT-PCR: a single-blinded study.
|
Diagn Mol Pathol
|
2006
|
0.90
|
|
25
|
Fibroblast growth factor receptor 1 gene amplification in pancreatic ductal adenocarcinoma.
|
Histopathology
|
2013
|
0.90
|
|
26
|
Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients.
|
J Thorac Oncol
|
2015
|
0.89
|
|
27
|
A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del).
|
Mod Pathol
|
2013
|
0.88
|
|
28
|
Gastrointestinal stromal tumors with KIT exon 9 mutations: Update on genotype-phenotype correlation and validation of a high-resolution melting assay for mutational testing.
|
Am J Surg Pathol
|
2013
|
0.84
|
|
29
|
Expression of xenobiotic and steroid hormone metabolizing enzymes in hepatocellular tumors of the non-cirrhotic liver.
|
Pathol Res Pract
|
2009
|
0.83
|
|
30
|
Therapeutic strategies in male breast cancer: clinical implications of chromosome 17 gene alterations and molecular subtypes.
|
Breast
|
2013
|
0.82
|
|
31
|
c-KIT codon 816 mutation in a recurrent and metastatic dysgerminoma of a 14-year-old girl: case study.
|
Virchows Arch
|
2004
|
0.82
|
|
32
|
Spatial Tumor Heterogeneity in Lung Cancer with Acquired Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance: Targeting High-Level MET-Amplification and EGFR T790M Mutation Occurring at Different Sites in the Same Patient.
|
J Thorac Oncol
|
2015
|
0.82
|
|
33
|
Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung.
|
Mod Pathol
|
2013
|
0.82
|
|
34
|
Down regulation and nuclear localization of human beta-defensin-1 in pleomorphic adenomas of salivary glands.
|
Oral Oncol
|
2008
|
0.80
|
|
35
|
Familial gastrointestinal stromal tumors caused by the novel KIT exon 17 germline mutation N822Y.
|
Am J Surg Pathol
|
2008
|
0.80
|
|
36
|
Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues.
|
J Clin Pathol
|
2013
|
0.80
|
|
37
|
Reduced mRNA expression in paraffin-embedded tissue identifies MLH1- and MSH2-deficient colorectal tumours and potential mutation carriers.
|
Virchows Arch
|
2008
|
0.80
|
|
38
|
KIT codon 558 insertions in gastrointestinal stromal tumors. Analysis of 17 rare KIT mutants.
|
Hum Pathol
|
2008
|
0.79
|
|
39
|
qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.
|
BMC Mol Biol
|
2010
|
0.78
|
|
40
|
Analysis of chromosomal instability in focal cortical dysplasia of Taylor's balloon cell type.
|
Acta Neuropathol
|
2004
|
0.77
|
|
41
|
Detection of HPV 52, 58 and 87 in cervicovaginal intraepithelial lesions of HIV infected women.
|
Int J Mol Med
|
2005
|
0.77
|
|
42
|
Reactive lymphoid hyperplasia of the ocular surface: clinicopathologic features and search for infectious agents.
|
Acta Ophthalmol
|
2011
|
0.75
|
|
43
|
Prevalence of Chlamydia pneumoniae in nonrheumatic stenotic aortic valves.
|
Am Heart J
|
2002
|
0.75
|
|
44
|
Prevalence of cytomegalovirus in nonrheumatic stenotic aortic valves.
|
Am J Cardiol
|
2002
|
0.75
|