PubRank

Wei-Chiang Shen

Author PubWeight™ 71.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives. Pharm Res 2007 2.08
3 Fusion protein linkers: property, design and functionality. Adv Drug Deliv Rev 2012 1.67
4 Proinsulin-transferrin fusion protein as a novel long-acting insulin analog for the inhibition of hepatic glucose production. Diabetes 2013 1.44
5 Recombinant granulocyte colony-stimulating factor-transferrin fusion protein as an oral myelopoietic agent. Proc Natl Acad Sci U S A 2005 1.25
6 Human growth hormone-transferrin fusion protein for oral delivery in hypophysectomized rats. J Control Release 2009 1.10
7 Transcytosis of GCSF-transferrin across rat alveolar epithelial cell monolayers. Pharm Res 2003 1.09
8 Arsenite-oxidizing and arsenate-reducing bacteria associated with arsenic-rich groundwater in Taiwan. J Contam Hydrol 2010 1.09
9 Improving the oral efficacy of recombinant granulocyte colony-stimulating factor and transferrin fusion protein by spacer optimization. Pharm Res 2006 1.07
10 Resistance to the anti-proliferative activity of recombinant arginine deiminase in cell culture correlates with the endogenous enzyme, argininosuccinate synthetase. Cancer Lett 2003 1.04
11 Oral peptide and protein delivery: unfulfilled promises? Drug Discov Today 2003 1.04
12 Modulation of arginine metabolic pathways as the potential anti-tumor mechanism of recombinant arginine deiminase. Cancer Lett 2006 1.02
13 Insertion of the designed helical linker led to increased expression of tf-based fusion proteins. Pharm Res 2008 1.02
14 Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells. Biochem Pharmacol 2003 0.99
15 Reversible lipidization for the oral delivery of salmon calcitonin. J Control Release 2003 0.97
16 Drug evaluation: ADI-PEG-20--a PEGylated arginine deiminase for arginine-auxotrophic cancers. Curr Opin Mol Ther 2006 0.96
17 Blue light negatively regulates the sexual filamentation via the Cwc1 and Cwc2 proteins in Cryptococcus neoformans. Mol Microbiol 2005 0.95
18 Reversible lipidization for the oral delivery of leu-enkephalin. J Drug Target 2006 0.93
19 Quantitative comparison of membrane transduction and endocytosis of oligopeptides. Biochem Biophys Res Commun 2003 0.92
20 Accessibility of endothelial and inducible nitric oxide synthase to the intracellular citrulline-arginine regeneration pathway. Biochem Pharmacol 2005 0.92
21 The transepithelial transport of a G-CSF-transferrin conjugate in Caco-2 cells and its myelopoietic effect in BDF1 mice. Pharm Res 2004 0.92
22 Comparison of cationic and amphipathic cell penetrating peptides for siRNA delivery and efficacy. Mol Pharm 2011 0.91
23 Transferrin-oligomers as potential carriers in anticancer drug delivery. Pharm Res 2004 0.89
24 Effects of receptor binding on plasma half-life of bifunctional transferrin fusion proteins. Mol Pharm 2011 0.89
25 Membrane transduction of oligoarginine in HeLa cells is not mediated by macropinocytosis. Mol Pharm 2006 0.88
26 Effects of Lipofectamine 2000/siRNA complexes on autophagy in hepatoma cells. Mol Biotechnol 2012 0.87
27 A homolog of Ste6, the a-factor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans. Eukaryot Cell 2005 0.86
28 Reversible lipidization prolongs the pharmacological effect, plasma duration, and liver retention of octreotide. Pharm Res 2005 0.86
29 Comparison of monomeric and oligomeric transferrin as potential carrier in oral delivery of protein drugs. J Control Release 2005 0.86
30 Nuclear localization of cell-penetrating peptides is dependent on endocytosis rather than cytosolic delivery in CHO cells. Mol Pharm 2009 0.85
31 Recombinant peptide constructs for targeted cell penetrating peptide-mediated delivery. J Control Release 2012 0.84
32 Evidence that membrane transduction of oligoarginine does not require vesicle formation. Exp Cell Res 2005 0.84
33 Receptor-mediated activation of a proinsulin-transferrin fusion protein in hepatoma cells. J Control Release 2011 0.84
34 Disulfide and thioether linked cytochrome c-oligoarginine conjugates in HeLa cells. Int J Pharm 2008 0.83
35 Design of an in vivo cleavable disulfide linker in recombinant fusion proteins. Biotechniques 2010 0.83
36 The influence of net charge and charge distribution on cellular uptake and cytosolic localization of arginine-rich peptides. J Drug Target 2010 0.83
37 Characterization of transferrin receptor-mediated endocytosis and cellular iron delivery of recombinant human serum transferrin from rice (Oryza sativa L.). BMC Biotechnol 2012 0.82
38 Fatty acids as therapeutic auxiliaries for oral and parenteral formulations. Adv Drug Deliv Rev 2012 0.81
39 Cryptococcus neoformans mediator protein Ssn8 negatively regulates diverse physiological processes and is required for virulence. PLoS One 2011 0.80
40 Enhancement of insulin transport across primary rat alveolar epithelial cell monolayers by endogenous cellular factor(s). Pharm Res 2007 0.80
41 Mass spectrometry study of a transferrin-based protein drug reveals the key role of protein aggregation for successful oral delivery. Proc Natl Acad Sci U S A 2012 0.80
42 Tyrphostin A8 stimulates a novel trafficking pathway of apically endocytosed transferrin through Rab11-enriched compartments in Caco-2 cells. Am J Physiol Cell Physiol 2007 0.79
43 Accumulation of transferrin in Caco-2 cells: a possible mechanism of intestinal transferrin absorption. J Control Release 2007 0.79
44 MAP-mediated nuclear delivery of a cargo protein. J Drug Target 2012 0.79
45 Cytosolic delivery of a p16-peptide oligoarginine conjugate for inhibiting proliferation of MCF7 cells. J Control Release 2005 0.79
46 A screening for suppressor mutants reveals components involved in the blue light-inhibited sexual filamentation in Cryptococcus neoformans. Fungal Genet Biol 2008 0.79
47 Lipidization of human interferon-alpha: a new approach toward improving the delivery of protein drugs. J Control Release 2008 0.78
48 Effects of spermine-conjugated Bowman-Birk inhibitor (spermine-BBI) on carcinogenesis and cholesterol biosynthesis in mice. Pharm Res 2003 0.78
49 Fast preparation of fungal DNA for PCR screening. J Microbiol Methods 2011 0.78
50 Conjugation with cationic cell-penetrating peptide increases pulmonary absorption of insulin. Mol Pharm 2009 0.78
51 Pharmacokinetics of recombinant bifunctional fusion proteins. Expert Opin Drug Metab Toxicol 2012 0.77
52 Vesicle-to-cytosol transport of disulfide-linked cargo mediated by an amphipathic cell-penetrating peptide. J Drug Target 2012 0.77
53 Mating differentiation in Cryptococcus neoformans is negatively regulated by the Crk1 protein kinase. Fungal Genet Biol 2010 0.77
54 Structure-activity relationship of reversibly lipidized peptides: studies of fatty acid-desmopressin conjugates. Pharm Res 2002 0.77
55 Reversible lipidization of somatostatin analogues for the liver targeting. Eur J Pharm Biopharm 2008 0.76
56 Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers. Eur J Pharm Biopharm 2008 0.76
57 Phylogenetic study of two truffles, Tuber formosanum and Tuber furfuraceum, identified from Taiwan. FEMS Microbiol Lett 2009 0.76
58 Interaction between cell-penetrating peptides and acid-sensitive anionic oligopeptides as a model for the design of targeted drug carriers. Mol Pharm 2014 0.75
59 Molecular and functional expression of multidrug resistance-associated protein-1 in primary cultured rat alveolar epithelial cells. J Pharm Sci 2008 0.75