Bruce A Luxon

Author PubWeight™ 66.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. J Virol 2004 3.43
2 Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma. Clin Cancer Res 2007 2.77
3 Identification of NF-kappaB-dependent gene networks in respiratory syncytial virus-infected cells. J Virol 2002 1.97
4 Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury. Hepatology 2008 1.94
5 Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: mechanism for the antiviral effects of heme oxygenase? Hepatology 2010 1.75
6 Virus-host cell interactions during hepatitis C virus RNA replication: impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis. J Virol 2004 1.74
7 Pathway signature and cellular differentiation in clear cell renal cell carcinoma. PLoS One 2010 1.70
8 Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin. J Biol Chem 2008 1.67
9 Disease- and cell-specific expression of GP73 in human liver disease. Am J Gastroenterol 2004 1.65
10 Immunofluorescence assay and flow-cytometry selection of bead-bound aptamers. Nucleic Acids Res 2003 1.41
11 Survival strategy of obligately intracellular Ehrlichia chaffeensis: novel modulation of immune response and host cell cycles. Infect Immun 2004 1.34
12 Combinatorial selection and binding of phosphorothioate aptamers targeting human NF-kappa B RelA(p65) and p50. Biochemistry 2002 1.31
13 Stochastic regulation in early immune response. Biophys J 2005 1.31
14 Limited success of HCV antiviral therapy in United States veterans. Am J Gastroenterol 2002 1.27
15 The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. PLoS One 2012 1.27
16 Transcriptional profiling of mRNA expression in the mouse distal colon. Gastroenterology 2008 1.19
17 Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing. Nucleic Acids Res 2002 1.16
18 Genomic profiling identifies alterations in TGFbeta signaling through loss of TGFbeta receptor expression in human renal cell carcinogenesis and progression. Oncogene 2003 1.15
19 Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. J Biol Chem 2006 1.14
20 Intrahepatic gene expression profiles and alpha-smooth muscle actin patterns in hepatitis C virus induced fibrosis. Hepatology 2005 1.13
21 Gene expression profile of human lymphoid CEM cells sensitive and resistant to glucocorticoid-evoked apoptosis. Genomics 2003 1.13
22 Identification of differentially activated cell-signaling networks associated with pichinde virus pathogenesis by using systems kinomics. J Virol 2006 1.12
23 Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection. Gastroenterology 2012 1.09
24 Differential signaling networks induced by mild and lethal hemorrhagic fever virus infections. J Virol 2006 1.07
25 Getting the right cells to the array: Gene expression microarray analysis of cell mixtures and sorted cells. Cytometry A 2004 1.05
26 Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry. PLoS One 2010 1.03
27 Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways. J Neurosci 2012 0.97
28 Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex. Biochemistry 2003 0.97
29 Structure of hybrid backbone methylphosphonate DNA heteroduplexes: effect of R and S stereochemistry. Biochemistry 2002 0.97
30 Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells. J Biol Chem 2007 0.96
31 A rat model of smoke inhalation injury: influence of combustion smoke on gene expression in the brain. Toxicol Appl Pharmacol 2005 0.96
32 Thioaptamer decoy targeting of AP-1 proteins influences cytokine expression and the outcome of arenavirus infections. J Gen Virol 2007 0.95
33 ¹H and ³¹P NMR lipidome of ethanol-induced fatty liver. Alcohol Clin Exp Res 2010 0.93
34 Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-beta1 protein. Bioorg Med Chem Lett 2008 0.92
35 CadA negatively regulates Escherichia coli O157:H7 adherence and intestinal colonization. Infect Immun 2008 0.91
36 Separation of synthetic oligonucleotide dithioates from monothiophosphate impurities by anion-exchange chromatography on a mono-q column. Anal Biochem 2002 0.91
37 Proteomics improves the prediction of burns mortality: results from regression spline modeling. Clin Transl Sci 2012 0.90
38 Selection of thioaptamers for diagnostics and therapeutics. Ann N Y Acad Sci 2006 0.89
39 Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB. Bioorg Chem 2002 0.89
40 Analysis of the differential host cell nuclear proteome induced by attenuated and virulent hemorrhagic arenavirus infection. J Virol 2008 0.88
41 Attenuated and lethal variants of Pichindé virus induce differential patterns of NF-kappaB activation suggesting a potential target for novel therapeutics. Viral Immunol 2009 0.88
42 Solution structure, dynamics, and thermodynamics of the native state ensemble of the Sem-5 C-terminal SH3 domain. Biochemistry 2003 0.87
43 Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice. J Neurosci 2014 0.83
44 Structure-based vaccines provide protection in a mouse model of ehrlichiosis. PLoS One 2011 0.83
45 Identification of proteins bound to a thioaptamer probe on a proteomics array. Biochem Biophys Res Commun 2006 0.83
46 1H NMR-based metabonomic investigation of tributyl phosphate exposure in rats. Toxicol Lett 2010 0.82
47 The use of DNA microarrays to assess clinical samples: the transition from bedside to bench to bedside. Recent Prog Horm Res 2003 0.82
48 Detection of structural and metabolic changes in traumatically injured hippocampus by quantitative differential proteomics. J Neurotrauma 2012 0.82
49 Hepatitis C virus core protein enhances Telomerase activity in Huh7 cells. J Med Virol 2010 0.82
50 Effects of progesterone treatment on expression of genes involved in uterine quiescence. Reprod Sci 2011 0.81
51 Proteomic analysis of Pichindé virus infection identifies differential expression of prothymosin-alpha. J Biomed Biotechnol 2010 0.80
52 Combinatorial selection and edited combinatorial selection of phosphorothioate aptamers targeting human nuclear factor-kappaB RelA/p50 and RelA/RelA. Biochemistry 2004 0.80
53 Use of surface enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS) to study protein expression in a rat model of cocaine withdrawal. J Neurosci Methods 2006 0.80
54 NMR structure of the Apo-S100P protein. J Biomol NMR 2004 0.80
55 Vaccines based on structure-based design provide protection against infectious diseases. Expert Rev Vaccines 2013 0.79
56 Global transcription profiling and virulence potential of Streptococcus pneumoniae after serial passage. Gene 2009 0.78
57 The hepatocellular bile acid transporter Ntcp facilitates uptake of the lethal mushroom toxin alpha-amanitin. Arch Toxicol 2003 0.78
58 Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation. Surgery 2005 0.76
59 Differential protein expression profiles of gastric epithelial cells following Helicobacter pylori infection using ProteinChips. J Proteome Res 2005 0.75
60 Investigation of chemometric instrumental transfer methods for high-resolution NMR. Anal Chem 2009 0.75