PubRank

Sanford J Shattil

Author PubWeight™ 79.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Talin binding to integrin beta tails: a final common step in integrin activation. Science 2003 7.56
2 Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc Natl Acad Sci U S A 2003 4.03
3 Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Curr Biol 2006 3.81
4 Integrin regulation. Curr Opin Cell Biol 2005 3.80
5 Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. J Cell Biol 2002 2.92
6 RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences. J Biol Chem 2008 2.29
7 Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol 2007 2.27
8 The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend. Blood 2008 2.22
9 An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nat Med 2009 2.10
10 The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation. J Clin Invest 2007 1.95
11 Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3. J Cell Biol 2008 1.93
12 Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets. Blood 2008 1.73
13 Matrix-specific suppression of integrin activation in shear stress signaling. Mol Biol Cell 2006 1.67
14 Specification of the direction of adhesive signaling by the integrin beta cytoplasmic domain. J Biol Chem 2005 1.65
15 Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling. Proc Natl Acad Sci U S A 2002 1.64
16 Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton. J Biol Chem 2002 1.59
17 Role for ADAP in shear flow-induced platelet mechanotransduction. Blood 2009 1.55
18 Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. Blood 2004 1.55
19 Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout. Blood 2007 1.54
20 The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains. J Biol Chem 2002 1.46
21 Detection of integrin alpha IIbbeta 3 clustering in living cells. J Biol Chem 2003 1.45
22 Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells. Mol Cell Biol 2006 1.41
23 Open access, yes! Open excess, no! Blood 2004 1.40
24 PTP-1B is an essential positive regulator of platelet integrin signaling. J Cell Biol 2005 1.34
25 Proximal, selective, and dynamic interactions between integrin alphaIIbbeta3 and protein tyrosine kinases in living cells. J Cell Biol 2004 1.33
26 Microfluidic devices for studies of shear-dependent platelet adhesion. Lab Chip 2008 1.32
27 Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta. J Biol Chem 2004 1.32
28 Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins. J Cell Sci 2011 1.27
29 Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling. J Exp Med 2002 1.24
30 Platelet integrins and immunoreceptors. Immunol Rev 2007 1.24
31 The mechanism of kindlin-mediated activation of integrin αIIbβ3. Curr Biol 2013 1.22
32 The oligodendrocyte precursor mitogen PDGF stimulates proliferation by activation of alpha(v)beta3 integrins. EMBO J 2002 1.18
33 Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in platelets. Biochem J 2002 1.12
34 Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3. PLoS One 2012 1.08
35 Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. J Biol Chem 2002 1.05
36 A (blood) smear campaign. Blood 2003 1.05
37 The primacy of β1 integrin activation in the metastatic cascade. PLoS One 2012 1.03
38 ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. Blood 2006 1.00
39 Integrin alphaV is necessary for gastrulation movements that regulate vertebrate body asymmetry. Development 2010 0.92
40 Differences in regulation of Drosophila and vertebrate integrin affinity by talin. Mol Biol Cell 2008 0.90
41 Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation. Blood 2004 0.90
42 Protein-protein interactions in platelet alphaIIbbeta3 signaling. Semin Thromb Hemost 2004 0.88
43 Amino acid changes in Drosophila alphaPS2betaPS integrins that affect ligand affinity. J Biol Chem 2005 0.88
44 Development and analysis of megakaryocytes from murine embryonic stem cells. Methods Enzymol 2003 0.88
45 The zebrafish vitronectin receptor: characterization of integrin alphaV and beta3 expression patterns in early vertebrate development. Dev Dyn 2007 0.87
46 Group IVA cytosolic phospholipase A2 (cPLA2alpha) and integrin alphaIIbbeta3 reinforce each other's functions during alphaIIbbeta3 signaling in platelets. Blood 2008 0.86
47 Platelet integrin adhesive functions and signaling. Methods Enzymol 2007 0.85
48 C-terminal COOH of integrin β1 is necessary for β1 association with the kindlin-2 adapter protein. J Biol Chem 2014 0.83
49 Bloodlines: the importance of mentoring for the future of hematology. Blood 2006 0.82
50 Letter to authors and readers regarding the new NIH policy on public access. Blood 2005 0.75