Published in Chem Biol Interact on October 30, 2008
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Evolutionary analysis of mammalian enamelin, the largest enamel protein, supports a crucial role for the 32-kDa peptide and reveals selective adaptation in rodents and primates. J Mol Evol (2009) 1.11
ALDH2 in alcoholic heart diseases: molecular mechanism and clinical implications. Pharmacol Ther (2011) 1.09
Zebrafish: a model for the study of addiction genetics. Hum Genet (2011) 1.03
Aldehyde dehydrogenase-2 (ALDH2) ameliorates chronic alcohol ingestion-induced myocardial insulin resistance and endoplasmic reticulum stress. J Mol Cell Cardiol (2009) 1.02
Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample. Alcohol Clin Exp Res (2011) 0.95
Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model. FASEB J (2009) 0.94
Ethanol metabolism and osmolarity modify behavioral responses to ethanol in C. elegans. Alcohol Clin Exp Res (2012) 0.92
Maternal alcohol consumption, alcohol metabolism genes, and the risk of oral clefts: a population-based case-control study in Norway, 1996-2001. Am J Epidemiol (2010) 0.89
The role of ALDH2 and ADH1B polymorphism in alcohol consumption and stroke in Han Chinese. Hum Genomics (2011) 0.86
The genetics of alcohol dependence: advancing towards systems-based approaches. Drug Alcohol Depend (2012) 0.85
Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. Oxid Med Cell Longev (2016) 0.80
Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample. Am J Med Genet B Neuropsychiatr Genet (2014) 0.79
Reduction of ethanol consumption in alcohol-preferring rats by dual expression gene transfer. Alcohol Alcohol (2012) 0.78
ADH1C Ile350Val polymorphism and cancer risk: evidence from 35 case-control studies. PLoS One (2012) 0.77
An optimized method for the measurement of acetaldehyde by high-performance liquid chromatography. Alcohol Clin Exp Res (2011) 0.77
Evaluation of the influence of alcohol dehydrogenase polymorphisms on alcohol elimination rates in African Americans. Alcohol Clin Exp Res (2013) 0.77
Regulation of ethanol-related behavior and ethanol metabolism by the Corazonin neurons and Corazonin receptor in Drosophila melanogaster. PLoS One (2014) 0.77
Association between in vivo alcohol metabolism and genetic variation in pathways that metabolize the carbon skeleton of ethanol and NADH reoxidation in the alcohol challenge twin study. Alcohol Clin Exp Res (2012) 0.76
Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption? Alcohol Clin Exp Res (2011) 0.76
Case-control association testing of common variants from sequencing of DNA pools. PLoS One (2013) 0.75
Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene. Oncotarget (2016) 0.75
Alcohol Consumption, Aldehyde Dehydrogenase 2 Gene Polymorphisms, and Cardiovascular Health in Korea. Yonsei Med J (2017) 0.75
Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population. Colomb Med (Cali) (2015) 0.75
Re-defininG AddiC(CH3)Tion: genomics and epigenomics on substance use disorders. Mol Genet Genomic Med (2014) 0.75
Ethanol pharmacokinetics in neonates and infants. Curr Ther Res Clin Exp (2014) 0.75
A Bayesian Approach for Population Pharmacokinetic Modeling of Alcohol in Japanese Individuals. Curr Ther Res Clin Exp (2017) 0.75
Associations between Genomic Variants in Alcohol Dehydrogenase (ADH) Genes and Alcohol Symptomatology in American Indians and European Americans: Distinctions and Convergence. Alcohol Clin Exp Res (2017) 0.75
Outcomes of thrombolytic therapy for acute ischemic stroke in Chinese patients: the Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) study. Stroke (2010) 1.79
Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations. Hum Genomics (2009) 1.17
Functional assessment of human alcohol dehydrogenase family in ethanol metabolism: significance of first-pass metabolism. Alcohol Clin Exp Res (2006) 1.10
Stenting for coronary intervention-related dissection of the left main coronary artery with extension to the aortic root: a case report. South Med J (2008) 1.09
Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. Alcohol Clin Exp Res (2004) 1.07
Alcohol sensitivity in Taiwanese men with different alcohol and aldehyde dehydrogenase genotypes. J Formos Med Assoc (2002) 1.03
Pharmacokinetic and pharmacodynamic basis for partial protection against alcoholism in Asians, heterozygous for the variant ALDH2*2 gene allele. Pharmacogenet Genomics (2007) 1.00
Substrate specificity of human and yeast aldehyde dehydrogenases. Chem Biol Interact (2008) 0.98
Pharmacokinetic and pharmacodynamic basis for overcoming acetaldehyde-induced adverse reaction in Asian alcoholics, heterozygous for the variant ALDH2*2 gene allele. Pharmacogenet Genomics (2009) 0.98
Utility of 18F-FDG PET/CT for staging NK/T-cell lymphomas. Nucl Med Commun (2010) 0.95
Functionality of allelic variations in human alcohol dehydrogenase gene family: assessment of a functional window for protection against alcoholism. Pharmacogenetics (2004) 0.92
Delayed diagnosis of post-traumatic acute myocardial infarction complicated by congestive heart failure. J Emerg Med (2005) 0.92
Polyglutamine (PolyQ) diseases: genetics to treatments. Cell Transplant (2014) 0.91
Enhanced catalytic activity of Ce(1-x)M(x)O2 (M = Ti, Zr, and Hf) solid solution with controlled morphologies. Chem Commun (Camb) (2010) 0.91
Modulation of human T cells signaling transduction by lovastatin. Int J Cardiol (2008) 0.89
Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenase. J Biol Chem (2002) 0.89
A study of multiple biliary hamartomas based on 1697 liver biopsies. Eur J Gastroenterol Hepatol (2013) 0.88
Preoperative APACHE II and GCS scores as predictors of outcomes in patients with malignant MCA infarction after decompressive hemicraniectomy. Neurol India (2013) 0.88
Inhibition of human alcohol and aldehyde dehydrogenases by acetaminophen: Assessment of the effects on first-pass metabolism of ethanol. Alcohol (2013) 0.87
Involvement of nigrostriatal pathway in Japanese encephalitis with movement disorders: evidence from 99mTc-TRODAT-1 and 123I-IBZM SPECT imagings. Mol Imaging Biol (2009) 0.86
Oxidative status in patients with alcohol dependence: a clinical study in Taiwan. J Toxicol Environ Health A (2005) 0.86
The role of ALDH2 and ADH1B polymorphism in alcohol consumption and stroke in Han Chinese. Hum Genomics (2011) 0.86
Carvedilol, a new antioxidative beta-blocker, blocks in vitro human peripheral blood T cell activation by downregulating NF-kappaB activity. Cardiovasc Res (2003) 0.85
Multiple sclerosis presenting initially with a worsening of migraine symptoms. J Headache Pain (2013) 0.85
Immunochemical features in the classification of human alcohol dehydrogenase family. Alcohol (2006) 0.84
Synthesis, characterization, DNA binding properties and antioxidant activity of Ln(III) complexes with hesperetin-4-one-(benzoyl) hydrazone. Eur J Med Chem (2009) 0.84
Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human small intestine. Alcohol Clin Exp Res (2012) 0.83
Down-regulation of c-jun N-terminal kinase-activator protein-1 signaling pathway by Ginkgo biloba extract in human peripheral blood T cells. Biochem Pharmacol (2003) 0.81
Increased risk of cerebral hemorrhage in Chinese male heavy drinkers with mild liver disorder. Cerebrovasc Dis (2007) 0.81
Oxidation of methanol, ethylene glycol, and isopropanol with human alcohol dehydrogenases and the inhibition by ethanol and 4-methylpyrazole. Chem Biol Interact (2010) 0.81
Post-stroke mania precipitated by withdrawal of antidepressant in an elderly patient with chronic major depression. Gen Hosp Psychiatry (2011) 0.81
ALDH2*2 but not ADH1B*2 is a causative variant gene allele for Asian alcohol flushing after a low-dose challenge: correlation of the pharmacokinetic and pharmacodynamic findings. Pharmacogenet Genomics (2014) 0.80
Reversal of ophthalmic artery flow and stroke outcomes in Asian patients with acute ischemic stroke and unilateral severe cervical carotid stenosis. PLoS One (2013) 0.80
Synthesis, characterization, DNA binding properties, fluorescence studies and antioxidant activity of transition metal complexes with hesperetin-2-hydroxy benzoyl hydrazone. J Fluoresc (2010) 0.80
Acetaldehyde, polymorphisms and the cardiovascular system. Novartis Found Symp (2007) 0.80
Dominance of the inactive Asian variant over activity and protein contents of mitochondrial aldehyde dehydrogenase 2 in human liver. Alcohol Clin Exp Res (2013) 0.80
Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human pancreas: implications for pathogenesis of alcohol-induced pancreatic injury. Alcohol Clin Exp Res (2009) 0.79
Spontaneous early recanalization of an acute symptomatic critical stenosis of the extracranial internal carotid artery: a case report. Ann Vasc Surg (2008) 0.79
Local intra-arterial thrombolysis with urokinase for acute ischemic stroke before and after the approval of intravenous tissue plasminogen activator treatment in Taiwan. Ann Vasc Surg (2010) 0.78
Inhibition of human alcohol and aldehyde dehydrogenases by cimetidine and assessment of its effects on ethanol metabolism. Chem Biol Interact (2012) 0.78
Establishment of steady-state metabolism of ethanol in perfused rat liver: the quantitative analysis using kinetic mechanism-based rate equations of alcohol dehydrogenase. Alcohol (2010) 0.78
Heavy binge drinking may increase risk of stroke in nonalcoholic hypertensives carrying variant ALDH2*2 gene allele. Acta Neurol Taiwan (2012) 0.78
Irbesartan inhibits human T-lymphocyte activation through downregulation of activator protein-1. Br J Pharmacol (2004) 0.78
The metabolic role of human ADH3 functioning as ethanol dehydrogenase. FEBS Lett (2003) 0.78
Association between plasma levels of hyaluronic acid and functional outcome in acute stroke patients. J Neuroinflammation (2014) 0.78
Evaluation of milk basic protein supplementation on bone density and bone metabolism in Chinese young women. Eur J Nutr (2009) 0.78
Alcohol abuse and related factors in Asia. Int Rev Psychiatry (2008) 0.77
Clinical and radiologic manifestations of H1N1 virus infection associated with neurological complications: a case report. Neurologist (2011) 0.77
Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients. PLoS One (2012) 0.77
Carvedilol differentially regulates cytokine production from activated human peripheral blood mononuclear cells. Cardiovasc Drugs Ther (2004) 0.77
Homocysteine induces cerebral endothelial cell death by activating the acid sphingomyelinase ceramide pathway. Prog Neuropsychopharmacol Biol Psychiatry (2013) 0.76
Depression in Chinese immigrants. Overcoming the cultural stronghold on symptom report. Adv Nurse Pract (2009) 0.76
Early Idiopathic Normal Pressure Hydrocephalus Patients With Neuropsychological Impairment Are Associated With Increased Fractional Anisotropy in the Anterior Thalamic Nucleus. Medicine (Baltimore) (2016) 0.75
[Biodistribution of (18)F-NaF as an imaging agent in osteoporotic rats for position emission tomography]. Nan Fang Yi Ke Da Xue Xue Bao (2008) 0.75
High Agatston Calcium Score of Intracranial Carotid Artery: A Significant Risk Factor for Cognitive Impairment. Medicine (Baltimore) (2015) 0.75
Middle Cerebral Artery Calcification: Association With Ischemic Stroke. Medicine (Baltimore) (2015) 0.75
Risk factor analysis of 167 patients with high myopia. Int J Ophthalmol (2010) 0.75
Molecular cloning and kinetic characterization of an aldehyde dehydrogenase gene in Klebsiella pneumoniae. J Formos Med Assoc (2005) 0.75
Combination treatment of interferon β-1b and warfarin for a patient with Baló's concentric sclerosis and antiphospholipid syndrome. Neurologist (2015) 0.75
(99m)Tc-TRODAT-1 and (123)I-IBZM SPECT studies in a patient with extrapontine myelinolysis with parkinsonian features. Ann Nucl Med (2009) 0.75
Cerebral venous thrombosis initially presenting with left occipital hemorrhage and headache. Blood Coagul Fibrinolysis (2010) 0.75
Carvedilol modulates in-vitro granulocyte-macrophage colony-stimulating factor-induced interleukin-10 production in U937 cells and human monocytes. Immunol Invest (2003) 0.75
Effect of head elevation on cerebral blood flow velocity in post-cerebral operation patients. J Nurs Res (2003) 0.75
Acute bilateral hearing loss as a "worsening sign" in a patient with critical basilar artery stenosis. J Clin Neurosci (2012) 0.75
Relation of genotypes of alcohol metabolizing enzymes and mortality of liver diseases in patients with alcohol dependence. Addict Biol (2004) 0.75
Steady-state metabolism of ethanol in perfused rat livers treated with cyanamide: quantitative analysis of acetaldehyde effects on the metabolic flux rates. Alcohol Clin Exp Res (2015) 0.75
A thrombophilic patient with a dural arteriovenous fistula presenting sensory aphasia and complicated with an acute pulmonary embolism. Neurologist (2008) 0.75
Status epilepticus associated with initiation of theophylline in an elderly patient with diabetic ketoacidosis. Neurol India (2007) 0.75