| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.
|
J Clin Invest
|
1972
|
2.18
|
|
2
|
Tissue differences in the concentration of triiodothyronine nuclear binding sites in the rat: liver, kidney, pituitary, heart, brain, spleen, and testis.
|
Endocrinology
|
1974
|
2.17
|
|
3
|
Specific nuclear triiodothyronine binding sites in rat liver and kidney.
|
J Clin Endocrinol Metab
|
1972
|
2.06
|
|
4
|
Quantitation of extrathyroidal conversion of L-thyroxine to 3,5,3'-triiodo-L-thyronine in the rat.
|
J Clin Invest
|
1971
|
1.94
|
|
5
|
Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans.
|
N Engl J Med
|
1987
|
1.87
|
|
6
|
Limited binding capacity sites for L-triiodothyronine in rat liver nuclei. Nuclear-cytoplasmic interrelation, binding constants, and cross-reactivity with L-thyroxine.
|
J Clin Invest
|
1974
|
1.73
|
|
7
|
Molecular basis of thyroid hormone-dependent brain development.
|
Endocr Rev
|
1997
|
1.66
|
|
8
|
The metabolic significance of exchangeable cellular thyroxine.
|
Recent Prog Horm Res
|
1969
|
1.63
|
|
9
|
Advances in our understanding of thyroid hormone action at the cellular level.
|
Endocr Rev
|
1987
|
1.57
|
|
10
|
Binding of selected iodothyronine analogues to receptor sites of isolated rat hepatic nuclei. High correlation between structural requirements for nuclear binding and biological activity.
|
J Biol Chem
|
1975
|
1.44
|
|
11
|
Differences in primary cellular factors influencing the metabolism and distribution of 3,5,3'-L-triiodothyronine and L-thyroxine.
|
J Clin Invest
|
1970
|
1.43
|
|
12
|
Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats.
|
J Biol Chem
|
1990
|
1.38
|
|
13
|
Ontogenesis of 3,5,3'-triiodothyronine receptors in neonatal rat brain: dissociation between receptor concentration and stimulation of oxygen consumption by 3,5,3'-triiodothyronine.
|
Endocrinology
|
1978
|
1.30
|
|
14
|
Nuclear receptors and the initiation of thyroid hormone action.
|
Recent Prog Horm Res
|
1976
|
1.28
|
|
15
|
Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat.
|
J Clin Invest
|
1991
|
1.27
|
|
16
|
Nuclear triiodothyronine receptor sites in brain: probable identity with hepatic receptors and regional distribution.
|
Endocrinology
|
1978
|
1.24
|
|
17
|
Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated.
|
J Clin Invest
|
1977
|
1.22
|
|
18
|
Specific triiodothyronine binding sites in the anterior pituitary of the rat.
|
Science
|
1972
|
1.17
|
|
19
|
Binding of 3,5,3'-triiodothyronine (T3) and its analogs to the in vitro translational products of c-erbA protooncogenes: differences in the affinity of the alpha- and beta-forms for the acetic acid analog and failure of the human testis and kidney alpha-2 products to bind T3.
|
Mol Endocrinol
|
1990
|
1.14
|
|
20
|
Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: possible relationship to hormonal activity.
|
Biochem Biophys Res Commun
|
1973
|
1.11
|
|
21
|
Nuclear binding capacity appears to limit the hepatic response to L-triiodothyronine (T3).
|
Endocr Res Commun
|
1975
|
1.11
|
|
22
|
Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction.
|
J Biol Chem
|
1986
|
1.11
|
|
23
|
Effect of phenobarbital administration on the subcellular distribution of 125-I-thyroxine in rat liver: mportance of microsomal binding.
|
Endocrinology
|
1969
|
1.09
|
|
24
|
Partial purification of the triiodothyronine receptor from rat liver nuclei. Differences in the chromatographic mobility of occupied and unoccupied sites.
|
J Biol Chem
|
1977
|
1.08
|
|
25
|
Nonlinear (amplified) relationship between nuclear occupancy by triiodothyronine and the appearance rate of hepatic alpha-glycerophosphate dehydrogenase and malic enzyme in the rat.
|
J Clin Invest
|
1978
|
1.07
|
|
26
|
Determination of common parameters fo iodothyronine metabolism and distribution in man by noncompartmental analysis.
|
J Clin Endocrinol Metab
|
1975
|
1.05
|
|
27
|
Gene transcription in differentiating immature T cell receptor(neg) thymocytes resembles antigen-activated mature T cells.
|
J Exp Med
|
1993
|
1.03
|
|
28
|
Stereospecific transport of triiodothyronine from plasma to cytosol and from cytosol to nucleus in rat liver, kidney, brain, and heart.
|
J Clin Invest
|
1985
|
1.01
|
|
29
|
Synergism of thyroid hormone and high carbohydrate diet in the induction of lipogenic enzymes in the rat. Mechanisms and implications.
|
J Clin Invest
|
1980
|
1.00
|
|
30
|
Paradoxical effects of cycloheximide on the ultra-rapid induction of two hepatic mRNA sequences by triiodothyronine (T3).
|
Endocrinology
|
1982
|
1.00
|
|
31
|
Glucose and triiodothyronine both induce malic enzyme in the rat hepatocyte culture: evidence that triiodothyronine multiplies a primary glucose-generated signal.
|
J Clin Invest
|
1981
|
0.98
|
|
32
|
Immunofluorescence localization of thyroid hormone receptor protein beta 1 and variant alpha 2 in selected tissues: cerebellar Purkinje cells as a model for beta 1 receptor-mediated developmental effects of thyroid hormone in brain.
|
Proc Natl Acad Sci U S A
|
1991
|
0.96
|
|
33
|
Thyroid hormone action 1994: the plot thickens.
|
Eur J Endocrinol
|
1994
|
0.95
|
|
34
|
Factors determining the level of activity of 3,5,3'-triiodothyronine-responsive hepatic enzymes in the starved rat.
|
Endocrinology
|
1980
|
0.95
|
|
35
|
Quantitation of rat liver messenger ribonucleic acid for malic enzyme during induction by thyroid hormone.
|
Biochemistry
|
1981
|
0.93
|
|
36
|
Isoform-specific 3,5,3'-triiodothyronine receptor binding capacity and messenger ribonucleic acid content in rat adenohypophysis: effect of thyroidal state and comparison with extrapituitary tissues.
|
Endocrinology
|
1996
|
0.93
|
|
37
|
The subunits of thyroglobulin.
|
Biochem J
|
1970
|
0.91
|
|
38
|
Comparison of the metabolism and distribution of L-triiodothyronine and triiodothyroacetic acid in the rat: a possible explanation of differential hormonal potency.
|
Endocrinology
|
1976
|
0.89
|
|
39
|
Immunocytochemical delineation of thyroid hormone receptor beta 2-like immunoreactivity in the rat central nervous system.
|
Endocrinology
|
1993
|
0.89
|
|
40
|
Letter: (to the editor). Erratum: revised calculations of common parameters of iodothyronine metabolism and distribution by noncompartmental analysis.
|
J Clin Endocrinol Metab
|
1975
|
0.89
|
|
41
|
Starvation and hypothyroidism exert an overlapping influence on rat hepatic messenger RNA activity profiles.
|
J Clin Invest
|
1983
|
0.89
|
|
42
|
Dissociation between thyroxine metabolism and hormonal action in phenobarbital-treated rats.
|
Endocrinology
|
1971
|
0.88
|
|
43
|
Relationship between the accumulation of pituitary growth hormone and nuclear occupancy by triiodothyronine in the rat.
|
J Clin Invest
|
1978
|
0.88
|
|
44
|
Tissue iodoprotein formation during the peripheral metabolism of the thyroid hormones.
|
J Clin Invest
|
1969
|
0.88
|
|
45
|
Rat hepatic mRNA-S14 and lipogenic enzymes during weaning: role of S14 in lipogenesis.
|
Am J Physiol
|
1987
|
0.87
|
|
46
|
Selective alterations in hepatic enzyme response after reduction of nuclear triiodothyronine receptor sites by partial hepatectomy and starvation.
|
Biochem Biophys Res Commun
|
1978
|
0.87
|
|
47
|
Decreased serum triiodothyronine in starving rats is due primarily to diminished thyroidal secretion of thyroxine.
|
J Clin Invest
|
1985
|
0.87
|
|
48
|
Increased deiodination of L-thyroxine and L-triiodothyronine by liver microsomes from rats treated with phenobarbital.
|
Nature
|
1969
|
0.87
|
|
49
|
Diurnal variation in hepatic expression of the rat S14 gene is synchronized by the photoperiod.
|
Endocrinology
|
1987
|
0.86
|
|
50
|
Nuclear receptors for 3,5,3'-triiodothyronine in human liver and kidney: characterization, quantitation, and similarities to rat receptors.
|
J Clin Endocrinol Metab
|
1979
|
0.86
|
|
51
|
Age-related reduction in response of hepatic enzymes to 3,5,3'-triiodothyronine administration.
|
Endocrinology
|
1979
|
0.85
|
|
52
|
Thyroid hormone-carbohydrate interaction in the rat: correlation between age-related reductions in the inducibility of hepatic malic enzyme by triiodo-L-thyronine and a high carbohydrate, fat-free diet.
|
J Clin Invest
|
1981
|
0.84
|
|
53
|
Physiologic and biochemical actions of thyroid hormone.
|
Pharmacol Ther B
|
1978
|
0.84
|
|
54
|
Quantitative assessment of pituitary resistance to thyroid hormone from plots of the logarithm of thyrotropin versus serum free thyroxine index.
|
J Clin Endocrinol Metab
|
2000
|
0.84
|
|
55
|
Thyroid hormone and circadian regulation of the binding activity of a liver-specific protein associated with the 5'-flanking region of the S14 gene.
|
J Biol Chem
|
1989
|
0.83
|
|
56
|
Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): implications for autoantigen modification during pathogenesis.
|
Clin Exp Immunol
|
2002
|
0.83
|
|
57
|
Triiodothyronine rapidly reverses inhibition of S14 gene transcription by glucagon.
|
Endocrinology
|
1988
|
0.83
|
|
58
|
Distribution and metabolism of L- and D-triiodothyronine (T3) in the rat: preferential accumulation of L-T3 by hepatic and cardiac nuclei as a probable explanation of the differential biological potency of T3 enantiomers.
|
Endocrinology
|
1983
|
0.83
|
|
59
|
Inhibition of malic enzyme induction by triiodothyronine in the diabetic rat: reversal by fructose feeding.
|
Metabolism
|
1980
|
0.83
|
|
60
|
The regulation of lipogenesis by thyroid hormone and its contribution to thermogenesis.
|
Endocrinology
|
1989
|
0.82
|
|
61
|
Nuclear receptors and thyroid hormone action: a progress report.
|
Fed Proc
|
1979
|
0.82
|
|
62
|
Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) modulates expression of the Purkinje cell protein-2 gene. A potential role for COUP-TF in repressing premature thyroid hormone action in the developing brain.
|
J Biol Chem
|
1998
|
0.82
|
|
63
|
Alpha-amanitin administration results in a temporary inhibition of hepatic enzyme induction by triiodothyronine: further evidence favoring a long-lived mediator of thyroid hormone action.
|
Endocrinology
|
1977
|
0.82
|
|
64
|
Triiodothyronine-stimulated formation of poly(A)-containing nuclear RNA and mRNA in rat liver.
|
Endocrinology
|
1978
|
0.81
|
|
65
|
Heparin administration appears to decrease cellular binding of thyroxine.
|
J Clin Endocrinol Metab
|
1973
|
0.81
|
|
66
|
Purkinje cell protein-2 cis-elements mediate repression of T3-dependent transcriptional activation.
|
Mol Cell Endocrinol
|
1997
|
0.81
|
|
67
|
Transcellular and transnuclear transport of 3,5,3'-triiodothyronine in isolated hepatocytes.
|
Endocrinology
|
1985
|
0.81
|
|
68
|
Slow fractional removal of nonextractable iodine from rat tissue after injection of labeled L-thyroxine and 3,5,3'-triiodo-L-thyronine. A possible clue to the mechanism of initiation and persistence of hormonal action.
|
J Clin Invest
|
1972
|
0.81
|
|
69
|
Triiodothyronine nuclear binding capacity in rat tissues correlates with a 6.0 kilobase (kb) and not a 2.6 kb messenger ribonucleic acid hybridization signal generated by a human c-erbA probe.
|
Mol Endocrinol
|
1988
|
0.81
|
|
70
|
An analysis of the interrelationship of nuclear and plasma triiodothyronine in the sea lamprey, lake trout, and rat: evolutionary considerations.
|
Endocrinology
|
1987
|
0.81
|
|
71
|
Opposing effects of glucagon and triiodothyronine on the hepatic levels of messenger ribonucleic acid S14 and the dependence of such effects on circadian factors.
|
J Clin Invest
|
1986
|
0.80
|
|
72
|
Transient stimulation of myelin basic protein gene expression in differentiating cultured oligodendrocytes: a model for 3,5,3'-triiodothyronine-induced brain development.
|
Endocrinology
|
1997
|
0.80
|
|
73
|
Immunofluorescent localization of thyroid hormone receptor isoforms in glial cells of rat brain.
|
Endocrinology
|
1994
|
0.80
|
|
74
|
Limitations in the conventional analysis of the interaction of triiodothyronine with solubilized nuclear receptor sites. Inapparent binding of triiodothyronine to nonspecific binding sites.
|
J Biol Chem
|
1981
|
0.80
|
|
75
|
Ontogeny of hepatic nuclear triiodothyronine receptor isoforms in the rat.
|
Endocrinology
|
1992
|
0.79
|
|
76
|
Time course of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and messenger ribonucleic acid, biliary lipid secretion, and hepatic cholesterol content in methimazole-treated hypothyroid and hypophysectomized rats after triiodothyronine administration: possible linkage of cholesterol synthesis to biliary secretion.
|
Endocrinology
|
1989
|
0.79
|
|
77
|
Thyroid hormone-, carbohydrate, and age-dependent regulation of a methylation site in the hepatic S14 gene.
|
Mol Endocrinol
|
1989
|
0.79
|
|
78
|
Beta receptor isoforms are not essential for thyroid hormone-dependent acceleration of PCP-2 and myelin basic protein gene expression in the developing brains of neonatal mice.
|
Mol Cell Endocrinol
|
1998
|
0.79
|
|
79
|
Quantitative determination of the thyroxine, triiodothyronine, monoiodotyrosine and diiodotyrosine content of desiccated thyroid.
|
Endocrinology
|
1966
|
0.79
|
|
80
|
Interaction of dietary carbohydrate and glucagon in regulation of rat hepatic messenger ribonucleic acid S14 expression: role of circadian factors and 3',5'-cyclic adenosine monophosphate.
|
Mol Endocrinol
|
1987
|
0.78
|
|
81
|
Stereospecific transport of triiodothyronine to cytoplasm and nucleus in GH1 cells.
|
Mol Cell Endocrinol
|
1986
|
0.78
|
|
82
|
Evidence for a factor in the sera of patients with nonthyroidal disease which inhibits iodothyronine binding by solid matrices, serum proteins, and rat hepatocytes.
|
J Clin Endocrinol Metab
|
1982
|
0.78
|
|
83
|
Effect of dichloroacetic acid on rat hepatic messenger RNA activity profiles.
|
Metabolism
|
1986
|
0.78
|
|
84
|
Thyroid hormone receptor isoform content in cultured type 1 and type 2 astrocytes.
|
Endocrinology
|
1996
|
0.77
|
|
85
|
Association of the thyroid hormone receptor with rat liver chromatin.
|
Biochemistry
|
1981
|
0.77
|
|
86
|
Regulation of gene S-14 by triiodothyronine in liver.
|
Horm Metab Res Suppl
|
1987
|
0.77
|
|
87
|
Relationship of red blood cell 131-I-L-triiodothyronine binding coefficient and cell maturation. 3. Binding to mature erythrocyte and reticulocyte cell membranes.
|
Endocrinology
|
1968
|
0.76
|
|
88
|
Thyroid hormones influence starvation-induced hepatic protein loss in the rat: possible role of thyroid hormones in the generation of labile protein.
|
Endocrinology
|
1980
|
0.76
|
|
89
|
Hepatic messenger ribonucleic acid activity profiles in experimental azotemia in the rat. Relationship to food intake and thyroid function.
|
J Clin Invest
|
1984
|
0.75
|
|
90
|
The thiol groups of thyroglobulin.
|
Biochem J
|
1967
|
0.75
|
|
91
|
Tissue-specific regulation of malic enzyme by thyroid hormone in the neonatal rat.
|
Biochem Biophys Res Commun
|
1996
|
0.75
|
|
92
|
The elusive cure: health care reform.
|
Calif Hosp
|
1992
|
0.75
|
|
93
|
Difference between thyroidectomized and hypophysectomized animals in their hepatic ribonucleic acid response to thyroid hormone.
|
Endocrinology
|
1980
|
0.75
|
|
94
|
An intraoral self-contained artificial larynx.
|
Otolaryngol Head Neck Surg
|
1982
|
0.75
|
|
95
|
Comparison of age-related decreases in the basal and carbohydrate inducible levels of lipogenic enzymes in adipose tissue and liver.
|
Metabolism
|
1983
|
0.75
|
|
96
|
TSH response to TRH in euthyroid, hypercholesterolemic patients treated with graded doses of dextrothyroxine.
|
Metabolism
|
1981
|
0.75
|
|
97
|
Self-esteem and self-reinforcement in men alcoholics.
|
J Stud Alcohol
|
1980
|
0.75
|
|
98
|
Prolonged fasting reduces rat hepatic beta 1 thyroid hormone receptor protein without changing the level of its messenger ribonucleic acid.
|
Endocrinology
|
1991
|
0.75
|
|
99
|
Triiodothyronine regulation of multiple rat hepatic genes: requirement for ongoing protein synthesis.
|
Mol Endocrinol
|
1987
|
0.75
|
|
100
|
Cycloheximide inhibits S-14 gene transcription and abolishes DNase I hypersensitive S-14 sites in the livers of euthyroid but not hypothyroid rats.
|
Mol Endocrinol
|
1987
|
0.75
|
|
101
|
Interaction of T3 and carbohydrate in the induction of lipogenic enzymes.
|
Life Sci
|
1981
|
0.75
|
|
102
|
Recent studies of thyroid hormone action at the hepatocellular level.
|
Horm Metab Res Suppl
|
1984
|
0.75
|
|
103
|
Distinguished service award.
|
Thyroid
|
1993
|
0.75
|
|
104
|
Interaction of thyroid hormones with target tissues: effects of hepatic mRNA population.
|
Prog Clin Biol Res
|
1979
|
0.75
|
|
105
|
Defensive style and performance on objective personality measures.
|
J Pers Assess
|
1979
|
0.75
|
|
106
|
Relationship of red blood cell 131-I-L-triiodothyronine binding coefficient and cell maturation. II. Effect of cell age and metabolic inhibitors.
|
Endocrinology
|
1967
|
0.75
|