Published in J Am Chem Soc on December 31, 2008
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Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1. J Am Chem Soc (2011) 1.01
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Local structure and global patterning of Cu2+ binding in fibrillar amyloid-β [Aβ(1-40)] protein. J Am Chem Soc (2012) 0.92
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Evidence for copper-dioxygen reactivity during alpha-synuclein fibril formation. J Am Chem Soc (2010) 0.81
Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle. J Biol Chem (2014) 0.80
On the involvement of copper binding to the N-terminus of the amyloid Beta Peptide of Alzheimer's disease: a computational study on model systems. Int J Alzheimers Dis (2011) 0.79
A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms. J Am Chem Soc (2015) 0.77
On the generation of OH(·) radical species from H2O2 by Cu(I) amyloid beta peptide model complexes: a DFT investigation. J Biol Inorg Chem (2015) 0.76
Identification of key structural features of the elusive Cu-Aβ complex that generates ROS in Alzheimer's disease. Chem Sci (2017) 0.76
Effect of C-terminal residues of Aβ on copper binding affinity, structural conversion and aggregation. PLoS One (2014) 0.76
Structure of the Reduced Copper Active Site in Preprocessed Galactose Oxidase: Ligand Tuning for One-Electron O2 Activation in Cofactor Biogenesis. J Am Chem Soc (2016) 0.75
Synthesis aided structural determination of amyloid-β(1-15) glycopeptides, new biomarkers for Alzheimer's disease. Chem Commun (Camb) (2014) 0.75
Copper ligation to soluble oligomers of the English mutant of the amyloid-β peptide yields a linear Cu(I) site that is resistant to O2 oxidation. Chem Commun (Camb) (2013) 0.75
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A Peroxynitrite Dicopper Complex: Formation via Cu-NO and Cu-O2 Intermediates and Reactivity via O-O Cleavage Chemistry. J Am Chem Soc (2016) 0.75
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Oxidative stress and the amyloid beta peptide in Alzheimer's disease. Redox Biol (2017) 0.75
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A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage. J Neurosci (2002) 1.37
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Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry (2004) 1.30
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Biochemistry of Tau in Alzheimer's disease and related neurological disorders. Expert Rev Proteomics (2008) 1.21
Amyloid-beta binds Cu2+ in a mononuclear metal ion binding site. J Am Chem Soc (2004) 1.19
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Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide. Biochemistry (2007) 1.06
Measurement of cerebrospinal fluid oxygen partial pressure in humans using MRI. Magn Reson Med (2005) 1.05
Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study. J Inorg Biochem (2003) 1.05
NMR reveals anomalous copper(II) binding to the amyloid Abeta peptide of Alzheimer's disease. J Am Chem Soc (2006) 1.02
Metal binding in amyloid beta-peptides shows intra- and inter-peptide coordination modes. Eur Biophys J (2006) 1.01
Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry (2007) 1.01
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The copper(II) adduct of the unstructured region of the amyloidogenic fragment derived from the human prion protein is redox-active at physiological pH. Inorg Chem (2007) 0.92
Products of Cu(II)-catalyzed oxidation in the presence of hydrogen peroxide of the 1-10, 1-16 fragments of human and mouse beta-amyloid peptide. J Inorg Biochem (2004) 0.91
The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease. Biophys J (2008) 0.90
Structural and thermodynamical properties of CuII amyloid-beta16/28 complexes associated with Alzheimer's disease. J Biol Inorg Chem (2006) 0.90
Ab initio modelling of the structure and redox behaviour of copper(I) bound to a His-His model peptide: relevance to the beta-amyloid peptide of Alzheimer's disease. J Biol Inorg Chem (2006) 0.89
Investigations of the molecular mechanism of metal-induced Abeta (1-40) amyloidogenesis. Biochemistry (2007) 0.89
Cu(II)-catalyzed oxidation of beta-amyloid peptide targets His13 and His14 over His6: Detection of 2-Oxo-histidine by HPLC-MS/MS. Chem Res Toxicol (2002) 0.88
Characterization of copper binding to the peptide amyloid-beta(1-16) associated with Alzheimer's disease. Biopolymers (2006) 0.87
Mechanistic studies of Cu(II) binding to amyloid-beta peptides and the fluorescence and redox behaviors of the resulting complexes. J Phys Chem B (2008) 0.86
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Substrate mediated reduction of copper-amyloid-beta complex in Alzheimer's disease. Chem Commun (Camb) (2008) 0.86
Computational study of the binding of CuII to Alzheimer's amyloid-beta peptide: do Abeta42 and Abeta40 bind copper in identical fashion? J Biol Inorg Chem (2008) 0.85
Model studies of cholesterol and ascorbate oxidation by copper complexes: relevance to Alzheimer's disease beta-amyloid metallochemistry. J Inorg Biochem (2005) 0.84
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Amyloid-beta binds Cu2+ in a mononuclear metal ion binding site. J Am Chem Soc (2004) 1.19
N-Terminal deletions modify the Cu2+ binding site in amyloid-beta. Biochemistry (2005) 1.19
Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid-beta peptide. Biochemistry (2008) 1.08
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Parallel-stranded guanine quadruplex interactions with a copper cationic porphyrin. Biochemistry (2004) 0.99
Affinity of Cu+ for the copper-binding domain of the amyloid-β peptide of Alzheimer's disease. Inorg Chem (2011) 0.99
Local structure and global patterning of Cu2+ binding in fibrillar amyloid-β [Aβ(1-40)] protein. J Am Chem Soc (2012) 0.92
Role of aspartate-1 in Cu(II) binding to the amyloid-beta peptide of Alzheimer's disease. J Am Chem Soc (2007) 0.89
Cu K-edge X-ray absorption spectroscopy reveals differential copper coordination within amyloid-β oligomers compared to amyloid-β monomers. Chem Commun (Camb) (2010) 0.85
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DNA oxidation in anionic reverse micelles: ruthenium-mediated damage at Guanine in single- and double-stranded DNA. Inorg Chem (2006) 0.75
Oxidation of guanine in double-stranded DNA by [Ru(bpy)2dppz]Cl2 in cationic reverse micelles. Inorg Chem (2007) 0.75