Published in Virus Genes on December 10, 2008
Animal models for the study of influenza pathogenesis and therapy. Antiviral Res (2009) 1.90
Intranasal DNA vaccination induces potent mucosal and systemic immune responses and cross-protective immunity against influenza viruses. Mol Ther (2010) 1.10
Contributions of the avian influenza virus HA, NA, and M2 surface proteins to the induction of neutralizing antibodies and protective immunity. J Virol (2009) 1.08
Advances and future challenges in recombinant adenoviral vectored H5N1 influenza vaccines. Viruses (2012) 0.89
Roles of the hemagglutinin of influenza A virus in viral entry and development of antiviral therapeutics and vaccines. Protein Cell (2010) 0.89
Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein. Virol J (2012) 0.84
NA proteins of influenza A viruses H1N1/2009, H5N1, and H9N2 show differential effects on infection initiation, virus release, and cell-cell fusion. PLoS One (2013) 0.82
A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus. Virol J (2010) 0.79
Protection against multiple subtypes of influenza viruses by virus-like particle vaccines based on a hemagglutinin conserved epitope. Biomed Res Int (2015) 0.79
Expression of H3N2 nucleoprotein in maize seeds and immunogenicity in mice. Plant Cell Rep (2015) 0.79
Intranasal DNA Vaccine for Protection against Respiratory Infectious Diseases: The Delivery Perspectives. Pharmaceutics (2014) 0.78
Cross-protection against influenza virus infection by intranasal administration of nucleoprotein-based vaccine with compound 48/80 adjuvant. Hum Vaccin Immunother (2015) 0.77
Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge. PLoS One (2016) 0.75
Intranasal Immunization of Mice to Avoid Interference of Maternal Antibody against H5N1 Infection. PLoS One (2016) 0.75
Comparison of multiple DNA vaccines for protection against cytomegalovirus infection in BALB/c mice. Virol J (2014) 0.75
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell (2008) 28.29
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature (2012) 8.66
Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res (2008) 8.49
Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project. J Rheumatol (2007) 5.23
Biventricular pacing in patients with bradycardia and normal ejection fraction. N Engl J Med (2009) 4.17
Safety and immunogenicity of 2009 pandemic influenza A H1N1 vaccines in China: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet (2009) 3.97
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med (2008) 3.69
MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res (2012) 3.53
Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell (2011) 3.39
Dietary glycemic index and glycemic load, carbohydrate and fiber intake, and measures of insulin sensitivity, secretion, and adiposity in the Insulin Resistance Atherosclerosis Study. Diabetes Care (2005) 2.86
Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection. Antimicrob Agents Chemother (2006) 2.69
Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047. AIDS (2002) 2.59
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. Nat Genet (2009) 2.51
FusionMap: detecting fusion genes from next-generation sequencing data at base-pair resolution. Bioinformatics (2011) 2.37
Dual multiple change-point model leads to more accurate recombination detection. Bioinformatics (2005) 2.31
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo. Cancer Cell (2012) 2.18
The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. Proc Natl Acad Sci U S A (2009) 2.09
Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol (2009) 2.05
Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine. J Clin Oncol (2010) 2.03
Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors. Clin Cancer Res (2009) 2.03
Induction of sarcomas by mutant IDH2. Genes Dev (2013) 2.02
DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection. J Infect Dis (2007) 2.02
A phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies. Clin Cancer Res (2009) 2.01
Spontaneous out-of-body experience in a child with refractory right temporoparietal epilepsy. J Neurosurg Pediatr (2014) 1.97
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Hemodynamic Study of Three Patterns of Flaps on Rats with a Novel Panoramic Photographing Technique Involved. Plast Reconstr Surg (2016) 1.91
Epigenetic resensitization to platinum in ovarian cancer. Cancer Res (2012) 1.88
Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species. Genome Res (2010) 1.81
Prevalence of hip symptoms and radiographic and symptomatic hip osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project. J Rheumatol (2009) 1.75
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci U S A (2009) 1.74
Mutation in nuclear pore component NUP155 leads to atrial fibrillation and early sudden cardiac death. Cell (2008) 1.70
Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. J Neurosci (2008) 1.67
Squamous cell carcinoma arising in lichen simplex chronicus. Eur J Dermatol (2010) 1.64
Biventricular pacing is superior to right ventricular pacing in bradycardia patients with preserved systolic function: 2-year results of the PACE trial. Eur Heart J (2011) 1.61
Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium. Circ Res (2010) 1.60
A gender- and sexual orientation-dependent spatial attentional effect of invisible images. Proc Natl Acad Sci U S A (2006) 1.55
Left atrial regional phasic strain, strain rate and velocity by speckle-tracking echocardiography: normal values and effects of aging in a large group of normal subjects. Int J Cardiol (2013) 1.52
Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction. Proc Natl Acad Sci U S A (2010) 1.51
No association between CYP1B1 Val432Leu polymorphism and breast cancer risk: a meta-analysis involving 40,303 subjects. Breast Cancer Res Treat (2009) 1.49
Minireview: epigenetic changes in ovarian cancer. Endocrinology (2009) 1.49
Arterial ischemic stroke: experience in Chinese children. Pediatr Neurol (2008) 1.47
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: subset analyses of the phase III Sorafenib Asia-Pacific trial. Eur J Cancer (2012) 1.45
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. N Engl J Med (2017) 1.39
Repair of basal cell carcinoma on the outer canthus via a bifurcated island flap. Dermatol Surg (2006) 1.39
Cascade control of superheated steam temperature with neuro-PID controller. ISA Trans (2012) 1.39
Vitamin D receptor protein expression in tumor tissue and prostate cancer progression. J Clin Oncol (2011) 1.39
Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a. J Mol Cell Cardiol (2008) 1.35
Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Am J Physiol Gastrointest Liver Physiol (2008) 1.34
MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3. Cancer Lett (2013) 1.31
Influenza A virus replication induces cell cycle arrest in G0/G1 phase. J Virol (2010) 1.30
Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein. PLoS One (2009) 1.30
Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice. J Clin Invest (2009) 1.28
Zfp143 regulates Nanog through modulation of Oct4 binding. Stem Cells (2008) 1.27
Imaging and characterizing influenza A virus mRNA transport in living cells. Nucleic Acids Res (2008) 1.26
Immediate risk for cardiovascular events and suicide following a prostate cancer diagnosis: prospective cohort study. PLoS Med (2009) 1.26
A reference methylome database and analysis pipeline to facilitate integrative and comparative epigenomics. PLoS One (2013) 1.26
A mutation found in the promoter region of the human survivin gene is correlated to overexpression of survivin in cancer cells. DNA Cell Biol (2004) 1.24
Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter. Biochem J (2007) 1.22
NMR-spectroscopy for nontargeted screening and simultaneous quantification of health-relevant compounds in foods: the example of melamine. J Agric Food Chem (2009) 1.21
A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. J Infect Dis (2010) 1.21
Ginsenoside Rg1 attenuates dopamine-induced apoptosis in PC12 cells by suppressing oxidative stress. Eur J Pharmacol (2003) 1.20
The applications of Vitamin E TPGS in drug delivery. Eur J Pharm Sci (2013) 1.20
Interaction of amyloid binding alcohol dehydrogenase/Abeta mediates up-regulation of peroxiredoxin II in the brains of Alzheimer's disease patients and a transgenic Alzheimer's disease mouse model. Mol Cell Neurosci (2007) 1.19
Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway. Cancer Lett (2010) 1.18
DAS181 inhibits H5N1 influenza virus infection of human lung tissues. Antimicrob Agents Chemother (2009) 1.18
Quantitative analysis of mitral valve morphology in mitral valve prolapse with real-time 3-dimensional echocardiography: importance of annular saddle shape in the pathogenesis of mitral regurgitation. Circulation (2012) 1.16
Targeting pandemic influenza: a primer on influenza antivirals and drug resistance. J Antimicrob Chemother (2010) 1.15
Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress. Acta Pharmacol Sin (2005) 1.13
A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data. PLoS One (2009) 1.13
Treatment of parainfluenza 3 infection with DAS181 in a patient after allogeneic stem cell transplantation. Clin Infect Dis (2011) 1.13
Hydrogen sulfide promotes root organogenesis in Ipomoea batatas, Salix matsudana and Glycine max. J Integr Plant Biol (2009) 1.13
Modification of nonstructural protein 1 of influenza A virus by SUMO1. J Virol (2010) 1.13
Arabidopsis P-glycoprotein19 participates in the inhibition of gravitropism by gravacin. Chem Biol (2007) 1.12
DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus. Genome Biol (2013) 1.12
RelB enhances prostate cancer growth: implications for the role of the nuclear factor-kappaB alternative pathway in tumorigenicity. Cancer Res (2009) 1.12
Estrogen stimulates estrogen-related receptor alpha gene expression through conserved hormone response elements. Endocrinology (2003) 1.11
Functional mechanism of the abscisic acid agonist pyrabactin. J Biol Chem (2010) 1.11
Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease. J Neurosci (2011) 1.11
Distribution of megaplasmids in Lactobacillus salivarius and other lactobacilli. J Bacteriol (2007) 1.11
Pharmaceutical nanotechnology for oral delivery of anticancer drugs. Adv Drug Deliv Rev (2012) 1.11
Protection against avian influenza H9N2 virus challenge by immunization with hemagglutinin- or neuraminidase-expressing DNA in BALB/c mice. Biochem Biophys Res Commun (2006) 1.10
Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein. PLoS One (2009) 1.10
SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a. Stem Cells (2007) 1.09
Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells. Mol Cancer Ther (2007) 1.09
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res (2013) 1.08
Responses to lightness variations in early human visual cortex. Curr Biol (2007) 1.08
Tissue-specific distribution of aberrant DNA methylation associated with maternal low-folate status in human neural tube defects. J Nutr Biochem (2011) 1.08
Quantification of left ventricular regional myocardial function using two-dimensional speckle tracking echocardiography in healthy volunteers--a multi-center study. Int J Cardiol (2012) 1.08
A rare Asian founder polymorphism of Raptor may explain the high prevalence of Moyamoya disease among East Asians and its low prevalence among Caucasians. Environ Health Prev Med (2009) 1.08
Hepatotoxicity or hepatoprotection? Pattern recognition for the paradoxical effect of the Chinese herb Rheum palmatum L. in treating rat liver injury. PLoS One (2011) 1.08
Berberine inhibits doxorubicin-triggered cardiomyocyte apoptosis via attenuating mitochondrial dysfunction and increasing Bcl-2 expression. PLoS One (2012) 1.05
Characterization of an H10N8 influenza virus isolated from Dongting lake wetland. Virol J (2011) 1.05
OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids. Front Biosci (Landmark Ed) (2009) 1.05
Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells. Epigenetics (2010) 1.05
SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB:p52 dimer and sensitizes prostate cancer cells to ionizing radiation. Mol Cancer Ther (2008) 1.04
Two Epstein-Barr virus-related serologic antibody tests in nasopharyngeal carcinoma screening: results from the initial phase of a cluster randomized controlled trial in Southern China. Am J Epidemiol (2012) 1.04
DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis. J Antimicrob Chemother (2009) 1.04
NaGdF4 nanoparticle-based molecular probes for magnetic resonance imaging of intraperitoneal tumor xenografts in vivo. ACS Nano (2012) 1.04
Neural activities in v1 create a bottom-up saliency map. Neuron (2012) 1.03