PubRank

Young-Soo Hong

Author PubWeight™ 30.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. Biochem Pharmacol 2006 1.91
2 Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors. Bioorg Med Chem Lett 2007 1.12
3 (Aryloxyacetylamino)benzoic acid analogues: A new class of hypoxia-inducible factor-1 inhibitors. J Med Chem 2007 1.10
4 Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli. J Ind Microbiol Biotechnol 2011 1.06
5 Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain. Microb Cell Fact 2012 1.02
6 Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera. J Pharmacol Exp Ther 2005 0.95
7 Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061. Arch Microbiol 2007 0.95
8 Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase. Appl Environ Microbiol 2012 0.94
9 Rational biosynthetic engineering for optimization of geldanamycin analogues. Chembiochem 2009 0.94
10 Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species. J Nat Prod 2009 0.92
11 Phenanthroquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells. J Nat Prod 2006 0.91
12 The first total synthesis of moracin O and moracin P, and establishment of the absolute configuration of moracin O. Chem Commun (Camb) 2009 0.91
13 Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod 2008 0.89
14 Cephalochromin, a FabI-directed antibacterial of microbial origin. Biochem Biophys Res Commun 2007 0.88
15 HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A. Int J Cancer 2011 0.86
16 Mutasynthesis of geldanamycin by the disruption of a gene producing starter unit: generation of structural diversity at the benzoquinone ring. Chembiochem 2007 0.86
17 pH-dependent structural change of the extracellular sensor domain of the DraK histidine kinase from Streptomyces coelicolor. Biochem Biophys Res Commun 2013 0.85
18 Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety. Chembiochem 2006 0.85
19 Geldanamycin inhibits TGF-beta signaling through induction of Hsp70. Arch Biochem Biophys 2009 0.85
20 Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1. J Nat Prod 2007 0.85
21 Construction of artificial biosynthetic pathways for resveratrol glucoside derivatives. J Microbiol Biotechnol 2014 0.83
22 New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus. J Antibiot (Tokyo) 2011 0.81
23 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427. J Microbiol Biotechnol 2008 0.81
24 Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites. Org Biomol Chem 2007 0.80
25 New sesquiterpene dimers from Inula britannica inhibit NF-kappaB activation and NO and TNF-alpha production in LPS-stimulated RAW264.7 cells. Planta Med 2006 0.80
26 A peroxisome proliferator-activated receptor-gamma agonist and other constituents from Chromolaena odorata. Planta Med 2009 0.79
27 An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB. J Nat Prod 2010 0.78
28 6-Alkylsalicylic acid analogues inhibit in vitro ATPase activity of heat shock protein 90. Arch Pharm Res 2010 0.77
29 Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification. Cancer Sci 2014 0.77
30 Overexpression of Shinorhizobium meliloti hemoprotein in Streptomyces lividans to enhance secondary metabolite production. J Microbiol Biotechnol 2007 0.77
31 Anticancer effects of the Hsp90 inhibitor 17-demethoxy-reblastatin in human breast cancer MDA-MB-231 cells. J Microbiol Biotechnol 2014 0.76
32 Fungal metabolites, sorbicillinoid polyketides and their effects on the activation of peroxisome proliferator-activated receptor gamma. J Antibiot (Tokyo) 2005 0.76
33 New geldanamycin analogs from Streptomyces hygroscopicus. J Microbiol Biotechnol 2012 0.76
34 Cytotoxic 6-alkylsalicylic acids from the endophytic Streptomyces laceyi. J Antibiot (Tokyo) 2006 0.76
35 A new dimeric neolignan from Magnolia grandiflora L. seeds. Arch Pharm Res 2014 0.75
36 Pharmacokinetics of 11-hydroxyaclacinomycin X (ID-6105), a novel anthracycline, after i.v. bolus multiple administration in rats. Arch Pharm Res 2005 0.75
37 Identification of three positive regulators in the geldanamycin PKS gene cluster of Streptomyces hygroscopicus JCM4427. J Microbiol Biotechnol 2010 0.75
38 Enhancement of geldanamycin production by pH shock in batch culture of Streptomyces hygroscopicus subsp. duamyceticus. J Microbiol Biotechnol 2008 0.75
39 Apoptosis induced by ID6105, a new anthracycline (11-hydroxyaclacinomycin X, Hyrubicin), and its anti-tumor effects on experimental tumor models. Cancer Chemother Pharmacol 2006 0.75
40 In vivo antitumor efficacy and cardiotoxicity of novel anthracycline ID6105 (11-hydroxy-aclacinomycin X, Hyrubicin). Cancer Chemother Pharmacol 2005 0.75