Polyol accumulation in cultured human lens epithelial cells.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 1907924)

Published in Exp Eye Res on January 01, 1991

Authors

L R Lin1, V N Reddy, F J Giblin, P F Kador, J H Kinoshita

Author Affiliations

1: Eye Research Institute, Oakland University, Rochester, MI 48309-4401.

Articles by these authors

Mechanisms initiating cataract formation. Proctor Lecture. Invest Ophthalmol (1974) 2.77

Daptomycin compared with teicoplanin and vancomycin for therapy of experimental Staphylococcus aureus endocarditis. Antimicrob Agents Chemother (1990) 2.30

AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach. Invest Ophthalmol Vis Sci (2001) 2.09

Cataracts in galactosemia. The Jonas S. Friedenwald Memorial Lecture. Invest Ophthalmol (1965) 1.86

Aldose reductase and p-crystallin belong to the same protein superfamily as aldehyde reductase. FEBS Lett (1987) 1.69

Diabeteslike preproliferative retinal changes in galactose-fed dogs. Arch Ophthalmol (1992) 1.61

Quantitation of galactosemic cataracts in dogs using magnetization transfer contrast-enhanced magnetic resonance imaging. Invest Ophthalmol Vis Sci (1996) 1.39

The pharmacology of aldose reductase inhibitors. Annu Rev Pharmacol Toxicol (1985) 1.31

Clinical evaluation of teicoplanin fluorescence polarization immunoassay. Antimicrob Agents Chemother (1991) 1.29

Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice. Invest Ophthalmol Vis Sci (2001) 1.29

NIH conference. Aldose reductase and complications of diabetes. Ann Intern Med (1984) 1.27

Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts. Biochem Biophys Res Commun (2000) 1.25

On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses. Exp Eye Res (1973) 1.24

Retinal capillaries: basement membrane thickening by galactosemia prevented with aldose reductase inhibitor. Science (1983) 1.20

Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats. Invest Ophthalmol Vis Sci (2001) 1.20

Flavonoids as inhibitors of lens aldose reductase. Science (1975) 1.19

Nuclear light scattering, disulfide formation and membrane damage in lenses of older guinea pigs treated with hyperbaric oxygen. Exp Eye Res (1995) 1.19

Human lens epithelial cell line. Exp Eye Res (1998) 1.18

Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl. Proc Natl Acad Sci U S A (1987) 1.18

Localization of aldose reductase in the human eye. Diabetes (1984) 1.18

The concentration and localization of heavy molecular weight aggregates in aging normal and cataractous human lenses. Exp Eye Res (1975) 1.16

Aldose reductase in diabetic cataracts. JAMA (1981) 1.16

Aldose reductase in diabetic complications of the eye. Metabolism (1979) 1.15

Calcium-induced aggregation of bovine lens alpha crystallins. Invest Ophthalmol (1972) 1.14

Glutathione in calf trabecular meshwork and its relation to aqueous humor outflow facility. Invest Ophthalmol Vis Sci (1983) 1.13

The absence of cataracts in mice with congenital hyperglycemia. Exp Eye Res (1974) 1.09

Diabetic and galactosaemic cataracts. Ciba Found Symp (1984) 1.08

Metabolism of glutathione in the lens. Exp Eye Res (1971) 1.08

Phase separation of X-irradiated lenses of rabbit. Invest Ophthalmol Vis Sci (1982) 1.07

Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor. Science (1973) 1.06

A biochemical evaluation of a cataract induced in a high-glucose medium. Invest Ophthalmol (1969) 1.05

Some properties of lens plasma membrane polypeptides isolated from normal human lenses. Exp Eye Res (1979) 1.03

Effects of growth factors on proliferation and differentiation in human lens epithelial cells in early subculture. Invest Ophthalmol Vis Sci (1995) 1.03

Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications. J Med Chem (1985) 1.03

Rat lens aldose reductase: rapid purification and comparison with human placental aldose reductase. Exp Eye Res (1983) 1.02

Aldose reductase localization in human retinal mural cells. Invest Ophthalmol Vis Sci (1983) 1.01

Inhibition of lens aldose reductase by flavonoids--their possible role in the prevention of diabetic cataracts. Biochem Pharmacol (1976) 1.01

Diabetic cataracts and flavonoids. Science (1977) 1.00

Conformation of gamma-crystallins of the calf lens: effects of temperature and denaturing agents. Exp Eye Res (1977) 0.99

Aldose reductase in the diabetic eye. XLIII Edward Jackson memorial lecture. Am J Ophthalmol (1986) 0.99

Biochemical changes in microwave cataracts. Doc Ophthalmol (1966) 0.98

Effects of lipid peroxidation products on the rat lens in organ culture: a possible mechanism of cataract initiation in retinal degenerative disease. Arch Biochem Biophys (1983) 0.98

The effects of xylose on the isolated lens. Invest Ophthalmol (1974) 0.98

Sorbitol, osmoregulation, and the complications of diabetes. J Clin Invest (1988) 0.98

Metabolism and function of glutathione in the lens. Ciba Found Symp (1984) 0.98

Activators and inhibitors of lens aldose reductase. Invest Ophthalmol (1971) 0.98

Philly mouse: a new model of hereditary cataract. Exp Eye Res (1980) 0.98

Impact of aging and hyperbaric oxygen in vivo on guinea pig lens lipids and nuclear light scatter. Invest Ophthalmol Vis Sci (2000) 0.98

Reepithelialization of denuded corneas in diabetic rats. Exp Eye Res (1980) 0.97

Swelling of the lens fibers. Exp Eye Res (1975) 0.97

Hyperbaric oxygen in vivo accelerates the loss of cytoskeletal proteins and MIP26 in guinea pig lens nucleus. Exp Eye Res (1999) 0.97

Ca++-induced cataract. Invest Ophthalmol Vis Sci (1982) 0.96

Rapid purification of human placental aldose reductase. Anal Biochem (1981) 0.96

Prevention of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by aldose reductase inhibitors. Arch Ophthalmol (1990) 0.95

Lens epithelium-derived growth factor: increased survival and decreased DNA breakage of human RPE cells induced by oxidative stress. Invest Ophthalmol Vis Sci (2001) 0.95

Characterization and purification of a mammalian osmoregulatory protein, aldose reductase, induced in renal medullary cells by high extracellular NaCl. J Biol Chem (1987) 0.95

The effect of diamide on lens glutathione and lens membrane function. Invest Ophthalmol (1970) 0.95

Altering the course of cataracts in diabetic rats. Invest Ophthalmol Vis Sci (1980) 0.94

Pharmacophor requirements of the aldose reductase inhibitor site. Mol Pharmacol (1983) 0.94

A study of growth factor receptors in human lens epithelial cells and their relationship to fiber differentiation. Exp Eye Res (1996) 0.94

Electron microscopic study of galactose-induced cataract. Invest Ophthalmol (1969) 0.94

Studies on the low molecular weight proteins of human lens. Exp Eye Res (1981) 0.93

Cross-linking of lens crystallins in a photodynamic system: a process mediated by singlet oxygen. Science (1980) 0.93

The effect of aldose reductase and its inhibition on sugar cataract formation. Metabolism (1986) 0.92

Corneal re-epithelialization in galactosemic rats. Invest Ophthalmol Vis Sci (1983) 0.92

Immunohistochemical localization for aldose reductase in diabetic lenses. Invest Ophthalmol Vis Sci (1987) 0.92

Membrane alterations during cataract development in the Nakano mouse lens. Invest Ophthalmol Vis Sci (1980) 0.92

Pharmacodynamics of methyl mercury in the rainbow trout (Salmo gairdneri): tissue uptake, distribution and excretion. Toxicol Appl Pharmacol (1973) 0.91

Localization of gamma-glutamyl transpeptidase in rabbit lens, ciliary process and cornea. Exp Eye Res (1973) 0.91

Prevention of basement membrane thickening in retinal capillaries by a novel inhibitor of aldose reductase, tolrestat. Diabetes (1986) 0.91

The effect of an aldose reductase inhibitor on the galactose-exposed rabbit lens. Biochim Biophys Acta (1968) 0.90

Pyridine nucleotides in ocular tissues as determined by the cycling assay. Exp Eye Res (1980) 0.90

Peroxide-induced effects on lens cation transport following inhibition of glutathione reductase activity in vitro. Exp Eye Res (1987) 0.89

Prevention of pericyte ghost formation in retinal capillaries of galactose-fed dogs by aldose reductase inhibitors. Arch Ophthalmol (1988) 0.89

Glutathione and lens epithelial function. Invest Ophthalmol (1976) 0.89

Mechanism of development of hereditary cataract in mice. Invest Ophthalmol (1971) 0.89

TEMPOL protects against lens DNA strand breaks and cataract in the x-rayed rabbit. Invest Ophthalmol Vis Sci (1998) 0.89

The effects of hyperbaric oxygen on the crystallins of cultured rabbit lenses: a possible catalytic role for copper. Exp Eye Res (2000) 0.89