PubRank

Ole Hindsgaul

Author PubWeight™ 37.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structure of the LpxC deacetylase with a bound substrate-analog inhibitor. Nat Struct Biol 2003 1.57
2 Metabolic cytometry. Glycosphingolipid metabolism in single cells. Anal Chem 2007 1.41
3 Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design. Biochemistry 2005 1.40
4 Yoctomole analysis of ganglioside metabolism in PC12 cellular homogenates. Electrophoresis 2007 1.26
5 Chemical cytometry: fluorescence-based single-cell analysis. Annu Rev Anal Chem (Palo Alto Calif) 2008 1.20
6 Nine orders of magnitude dynamic range: picomolar to millimolar concentration measurement in capillary electrophoresis with laser induced fluorescence detection employing cascaded avalanche photodiode photon counters. Anal Chem 2011 1.12
7 Synthesis of reference standards to enable single cell metabolomic studies of tetramethylrhodamine-labeled ganglioside GM1. Carbohydr Res 2006 1.11
8 Nucleophilic catalysis of carbohydrate oxime formation by anilines. J Org Chem 2010 1.04
9 The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells. Glycoconj J 2008 0.94
10 Synthesis of a carbohydrate-derived hydroxamic acid inhibitor of the bacterial enzyme (LpxC) involved in lipid A biosynthesis. Org Lett 2003 0.93
11 Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Org Biomol Chem 2011 0.93
12 Metabolic cytometry: capillary electrophoresis with two-color fluorescence detection for the simultaneous study of two glycosphingolipid metabolic pathways in single primary neurons. Anal Chem 2012 0.92
13 Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor. J Biol Chem 2008 0.91
14 Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate. J Biol Chem 2002 0.90
15 Investigation of nonspecific effects of different dyes in the screening of labeled carbohydrates against immobilized proteins. J Org Chem 2005 0.88
16 Frontal affinity chromatography-mass spectrometry. Nat Protoc 2007 0.87
17 Single cell ganglioside catabolism in primary cerebellar neurons and glia. Neurochem Res 2012 0.86
18 Preparation and electrophoretic separation of Bodipy-Fl-labeled glycosphingolipids. J Chromatogr A 2012 0.85
19 Monitoring the uptake of glycosphingolipids in Plasmodium falciparum-infected erythrocytes using both fluorescence microscopy and capillary electrophoresis with laser-induced fluorescence detection. Anal Chem 2010 0.84
20 High-throughput screening for enzyme inhibitors using frontal affinity chromatography with liquid chromatography and mass spectrometry. Anal Chem 2005 0.84
21 Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates. Glycobiology 2011 0.84
22 Capillary electrophoresis with three-color fluorescence detection for the analysis of glycosphingolipid metabolism. Analyst 2012 0.84
23 Screening for galectin-3 inhibitors from synthetic lacto-N-biose libraries using microscale affinity chromatography coupled to mass spectrometry. J Org Chem 2006 0.83
24 A very simple synthesis of GlcNAc-alpha-pyrophosphoryl-decanol: a substrate for the assay of a bacterial galactosyltransferase. Bioorg Med Chem Lett 2007 0.82
25 A simple synthesis of sugar nucleoside diphosphates by chemical coupling in water. Angew Chem Int Ed Engl 2012 0.82
26 Assessing the terminal glycosylation of a glycoprotein by the naked eye. Angew Chem Int Ed Engl 2007 0.81
27 Computational design and experimental evaluation of glycosyltransferase mutants: engineering of a blood type B galactosyltransferase with enhanced glucosyltransferase activity. Protein Eng Des Sel 2006 0.80
28 Biosynthesis of HNK-1 glycans on O-linked oligosaccharides attached to the neural cell adhesion molecule (NCAM): the requirement for core 2 beta 1,6-N-acetylglucosaminyltransferase and the muscle-specific domain in NCAM. J Biol Chem 2002 0.80
29 Synthesis of a 56 component library of sugar beta-peptides. Comb Chem High Throughput Screen 2002 0.80
30 Small-molecule sensing: a direct enzyme-linked immunosorbent assay for the monosaccharide Kdo. Angew Chem Int Ed Engl 2010 0.79
31 Characterization of the recognition of blood group B trisaccharide derivatives by the lectin from Marasmius oreades using frontal affinity chromatography-mass spectrometry. Glycoconj J 2002 0.79
32 Solid-phase oligosaccharide tagging (SPOT): Validation on glycolipid-derived structures. Angew Chem Int Ed Engl 2006 0.79
33 A convenient synthesis of GDP-D-rhamnose: the donor substrate for D-rhamnosyltransferase WbpZ from Pseudomonas aeruginosa PAO1. Bioorg Med Chem Lett 2013 0.79
34 Versatile Functionalization of Carbohydrate Hydroxyl Groups through Their O-Cyanomethyl Ethers. J Org Chem 1996 0.79
35 HMMC-1: a humanized monoclonal antibody with therapeutic potential against Müllerian duct-related carcinomas. Clin Cancer Res 2004 0.78
36 CMP substitutions preferentially inhibit polysialic acid synthesis. Glycobiology 2007 0.77
37 Assignment of the 1H, 13C and 15N resonances of the LpxC deacetylase from Aquifex aeolicus in complex with the substrate-analog inhibitor TU-514. J Biomol NMR 2004 0.77
38 Thiogalactopyranosides are resistant to hydrolysis by α-galactosidases. Chembiochem 2012 0.76
39 Time-resolved in-situ observation of starch polysaccharide degradation pathways. Chembiochem 2013 0.76
40 Synthesis and photolytic activation of 6''-O-2-nitrobenzyl uridine-5'-diphosphogalactose: a 'caged' UDP-Gal derivative. Carbohydr Res 2008 0.76
41 Fast and accurate quantitation of glucans in complex mixtures by optimized heteronuclear NMR spectroscopy. Anal Chem 2013 0.76
42 Synthesis of novel cyclic oligosaccharides: beta-1,6-thio-linked cycloglucopyranosides. Org Lett 2002 0.75
43 Evaluating carbohydrate-protein binding interactions using frontal affinity chromatography coupled to mass spectrometry. Methods Enzymol 2003 0.75
44 A simple chemical synthesis of sugar nucleoside diphosphates in water. Curr Protoc Nucleic Acid Chem 2013 0.75
45 Profiling of carbohydrate mixtures at unprecedented resolution using high-precision 1H-13C chemical shift measurements and a reference library. Analyst 2014 0.75
46 Nature's dendrimer: characterizing amylopectin as a multivalent host. Angew Chem Int Ed Engl 2013 0.75
47 Synthesis and NMR characterization of the six regioisomeric monophosphates of octyl beta-D-galactopyranosyl-(1 --> 4)-2-acetamido-2-deoxy-beta-D-glucopyranoside. Carbohydr Res 2002 0.75
48 Monitoring pathways of β-glucan degradation by enzyme mixtures in situ. Carbohydr Res 2012 0.75
49 A fluorescence assay that detects long branches in the starch polysaccharide amylopectin. Chem Commun (Camb) 2014 0.75
50 Synthesis of a galacto-configured C-ketoside-based gamma-sugar-amino acid and its use in peptide coupling reactions. Carbohydr Res 2006 0.75
51 Synthesis of O-glycolyl-linked neuraminic acids through a spirocyclic intermediate. Org Lett 2002 0.75
52 Glycan analysis via derivatization with a fluorogenic pyrylium dye. Carbohydr Res 2012 0.75
53 Probing helical hydrophobic binding sites in branched starch polysaccharides using NMR spectroscopy. Chemistry 2013 0.75