Published in Int J Cancer on March 15, 2009
Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers. Future Oncol (2010) 1.18
The molecular etiology and prevention of estrogen-initiated cancers: Ockham's Razor: Pluralitas non est ponenda sine necessitate. Plurality should not be posited without necessity. Mol Aspects Med (2013) 0.96
Depurinating naphthalene-DNA adducts in mouse skin related to cancer initiation. Free Radic Biol Med (2009) 0.92
Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice. PLoS Genet (2013) 0.91
Mechanism of DNA depurination by carcinogens in relation to cancer initiation. IUBMB Life (2011) 0.88
The etiology and prevention of breast cancer. Drug Discov Today Dis Mech (2012) 0.83
Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease. Free Radic Biol Med (2009) 0.81
Depurinating estrogen-DNA adducts, generators of cancer initiation: their minimization leads to cancer prevention. Clin Transl Med (2016) 0.79
In vitro interactions between 17β-estradiol and DNA result in formation of the hormone-DNA complexes. Int J Environ Res Public Health (2014) 0.79
Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease. IUBMB Life (2011) 0.79
Formation of diethylstilbestrol-DNA adducts in human breast epithelial cells and inhibition by resveratrol. J Steroid Biochem Mol Biol (2011) 0.79
Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells. PLoS One (2011) 0.79
Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A). Steroids (2014) 0.76
Array-based detection of persistent organic pollutants via cyclodextrin promoted energy transfer. Chem Commun (Camb) (2015) 0.75
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Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc Natl Acad Sci U S A (1997) 3.53
Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis (1998) 3.48
Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention. Biochim Biophys Acta (2006) 2.76
Prenatal diethylstilbestrol exposure and risk of breast cancer. Cancer Epidemiol Biomarkers Prev (2006) 1.91
Carcinogenicity of catechol estrogens in Syrian hamsters. J Steroid Biochem (1986) 1.82
Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. J Steroid Biochem Mol Biol (2003) 1.66
Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis. J Steroid Biochem Mol Biol (2003) 1.66
Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene. Oncogene (2001) 1.65
The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity. Chem Res Toxicol (2006) 1.65
Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo. Carcinogenesis (2003) 1.65
The molecular etiology of breast cancer: evidence from biomarkers of risk. Int J Cancer (2008) 1.62
Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens. Cancer Res (2000) 1.61
Breast cancer in mothers given diethylstilbestrol in pregnancy. N Engl J Med (1984) 1.58
Molecular characteristics of catechol estrogen quinones in reactions with deoxyribonucleosides. Chem Res Toxicol (1996) 1.57
Estrogen carcinogenesis in Syrian hamster tissues: role of metabolism. Fed Proc (1987) 1.56
17-Beta-estradiol induces transformation and tumorigenesis in human breast epithelial cells. FASEB J (2006) 1.50
Cancer risk in women prenatally exposed to diethylstilbestrol. Int J Cancer (2007) 1.47
Induction of A.T to G.C mutations by erroneous repair of depurinated DNA following estrogen treatment of the mammary gland of ACI rats. J Steroid Biochem Mol Biol (2006) 1.40
Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer. Carcinogenesis (2003) 1.39
Mutagenic activity of 4-hydroxyestradiol, but not 2-hydroxyestradiol, in BB rat2 embryonic cells, and the mutational spectrum of 4-hydroxyestradiol. Chem Res Toxicol (2006) 1.38
Imbalance of estrogen homeostasis in kidney and liver of hamsters treated with estradiol: implications for estrogen-induced initiation of renal tumors. Chem Res Toxicol (2001) 1.26
Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce mutations in human breast epithelial cells. Int J Cancer (2006) 1.22
Estrogen metabolism and formation of estrogen-DNA adducts in estradiol-treated MCF-10F cells. The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction and catechol-O-methyltransferase inhibition. J Steroid Biochem Mol Biol (2007) 1.16
Synthesis of the catechols of natural and synthetic estrogens by using 2-iodoxybenzoic acid (IBX) as the oxidizing agent. Steroids (2005) 1.13
Catechol estrogen metabolites and conjugates in different regions of the prostate of Noble rats treated with 4-hydroxyestradiol: implications for estrogen-induced initiation of prostate cancer. Carcinogenesis (2002) 1.13
The estrogen antagonist ICI-182-780 does not inhibit the transformation phenotypes induced by 17-beta-estradiol and 4-OH estradiol in human breast epithelial cells. Int J Oncol (2005) 1.12
Potential biomarker for early risk assessment of prostate cancer. Prostate (2006) 1.08
Novel biomarkers for risk of prostate cancer: results from a case-control study. Prostate (2009) 1.05
Breast cancer in mothers prescribed diethylstilbestrol in pregnancy. Further follow-up. JAMA (1993) 1.05
Relative carcinogenic activity of various synthetic and natural estrogens in the Syrian hamster kidney. Cancer Res (1983) 1.02
Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation. Free Radic Biol Med (2007) 1.01
Spectral characterization of catechol estrogen quinone (CEQ)-derived DNA adducts and their identification in human breast tissue extract. Chem Res Toxicol (2003) 1.01
Formation of depurinating N3Adenine and N7Guanine adducts by MCF-10F cells cultured in the presence of 4-hydroxyestradiol. Int J Cancer (2007) 1.00
Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine. J Steroid Biochem Mol Biol (2007) 0.96
Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor-alpha knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors. Carcinogenesis (2001) 0.95
Slow loss of deoxyribose from the N7deoxyguanosine adducts of estradiol-3,4-quinone and hexestrol-3',4'-quinone. Implications for mutagenic activity. Steroids (2004) 0.92
32P-postlabeling analysis of benzo[a]pyrene-DNA adducts formed in vitro and in vivo. Chem Res Toxicol (1992) 0.87
Characterization of semiquinone free radicals formed from stilbene catechol estrogens. An ESR spin stabilization and spin trapping study. J Biol Chem (1989) 0.87
Carcinogenicity and metabolic activation of hexestrol. Chem Biol Interact (1985) 0.86
Oxidative metabolism of the synthetic estrogens hexestrol and dienestrol indicates reactive intermediates. Adv Exp Med Biol (1981) 0.86
In vitro metabolism of diethylstilbestrol by hepatic, renal and uterine microsomes of rats and hamsters. Effects of different inducers. Biochem Pharmacol (1985) 0.83
Effects of various inducers on diethylstilbestrol metabolism, drug-metabolizing enzyme activities and the aromatic hydrocarbon (Ah) receptor in male Syrian golden hamster liver. J Steroid Biochem (1990) 0.78
The crystal and molecular structure of diethylstilbestrol. Acta Crystallogr B (1970) 0.77
Carbon-13 nuclear magnetic resonance study of meso-hexestrol and its derivatives. Chem Pharm Bull (Tokyo) (1988) 0.77
Diethylstilbestrol and clear cell vaginal carcinoma. Am J Med (1987) 0.76
Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention. Biochim Biophys Acta (2006) 2.76
The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity. Chem Res Toxicol (2006) 1.65
Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers: keynote lecture. Ann N Y Acad Sci (2006) 1.16
Synthesis of the catechols of natural and synthetic estrogens by using 2-iodoxybenzoic acid (IBX) as the oxidizing agent. Steroids (2005) 1.13
Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel. Mol Cancer Ther (2008) 1.13
Estrogen mediation of breast tumor formation involves estrogen receptor-dependent, as well as independent, genotoxic effects. Ann N Y Acad Sci (2009) 1.04
Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation. Free Radic Biol Med (2007) 1.01
Formation of depurinating N3Adenine and N7Guanine adducts by MCF-10F cells cultured in the presence of 4-hydroxyestradiol. Int J Cancer (2007) 1.00
Tamoxifen versus aromatase inhibitors for breast cancer prevention. Clin Cancer Res (2005) 0.94
Depurinating naphthalene-DNA adducts in mouse skin related to cancer initiation. Free Radic Biol Med (2009) 0.92
Slow loss of deoxyribose from the N7deoxyguanosine adducts of estradiol-3,4-quinone and hexestrol-3',4'-quinone. Implications for mutagenic activity. Steroids (2004) 0.92
Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA. Implications for the mechanism of tumor initiation by naphthalene. Chem Biol Interact (2006) 0.89
Mechanism of DNA depurination by carcinogens in relation to cancer initiation. IUBMB Life (2011) 0.88
Identification and quantification of stable DNA adducts formed from dibenzo[a,l]pyrene or its metabolites in vitro and in mouse skin and rat mammary gland. Chem Res Toxicol (2005) 0.87
The role of endogenous catechol quinones in the initiation of cancer and neurodegenerative diseases. Methods Enzymol (2004) 0.86
Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease. IUBMB Life (2011) 0.79
Androgens and estrogens in the etiology and prevention of breast cancer. Nutr Cancer (2006) 0.75