The future of artemisinins: natural, synthetic or recombinant?

PubWeight™: 0.78‹?›

🔗 View Article (PMID 19090980)

Published in J Biol on December 15, 2008

Authors

Marcel Hommel1

Author Affiliations

1: Institut Pasteur, 25-28 rue du Dr Roux, Paris 75724 Cedex 15, France. mhommel@pasteur.fr

Articles cited by this

Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature (2006) 13.86

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet (2005) 12.98

Qinghaosu (artemisinin): the price of success. Science (2008) 8.25

Identification of an antimalarial synthetic trioxolane drug development candidate. Nature (2004) 4.57

Predicting Global Fund grant disbursements for procurement of artemisinin-based combination therapies. Malar J (2008) 2.31

Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes. Antimicrob Agents Chemother (2007) 1.96

Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity. Malar J (2008) 1.69

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. BMC Biotechnol (2008) 1.68

Estimating antimalarial drugs consumption in Africa before the switch to artemisinin-based combination therapies (ACTs). Malar J (2007) 1.63

Ensuring sustained ACT production and reliable artemisinin supply. Malar J (2007) 1.54

Artemisinins: their growing importance in medicine. Trends Pharmacol Sci (2008) 1.43

Artemisia annua as a self-reliant treatment for malaria in developing countries. J Ethnopharmacol (2008) 1.18

Reaction of artemisinin with haemoglobin: implications for antimalarial activity. Biochem J (2005) 1.01

Second-generation antimalarial endoperoxides. Parasitol Today (1996) 0.86