PubRank

Hiroshi Sakaue

Author PubWeight™ 42.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat Med 2004 2.51
2 Role of Krüppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis. J Biol Chem 2005 2.45
3 Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice. Nat Med 2005 2.18
4 Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation. J Biol Chem 2003 1.75
5 Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver. J Clin Invest 2002 1.65
6 Enhancement of endothelial function inhibits left atrial thrombi development in an animal model of spontaneous left atrial thrombosis. Circ J 2014 1.45
7 Skp2 controls adipocyte proliferation during the development of obesity. J Biol Chem 2006 1.41
8 The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis. Mol Cell Biol 2005 1.35
9 Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes. Diabetes 2002 1.34
10 Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation. Nat Med 2008 1.27
11 Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression. Biochem Biophys Res Commun 2009 1.27
12 A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2. J Biol Chem 2004 1.24
13 Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy. Am J Hypertens 2010 1.22
14 Role of KLF15 in regulation of hepatic gluconeogenesis and metformin action. Diabetes 2010 1.14
15 RBP4, an unexpected adipokine. Nat Med 2006 1.09
16 Role of Krüppel-like factor 15 in PEPCK gene expression in the liver. Biochem Biophys Res Commun 2005 1.05
17 Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1. Diabetes 2007 0.97
18 Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation. Kobe J Med Sci 2009 0.97
19 Gene expression profiling in prostate cancer cells with Akt activation reveals Fra-1 as an Akt-inducible gene. Mol Cancer Res 2003 0.94
20 Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice. Cardiovasc Diabetol 2012 0.92
21 PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression. J Biol Chem 2008 0.92
22 Exendin-4, a glucagon-like peptide-1 receptor agonist, attenuates neointimal hyperplasia after vascular injury. Eur J Pharmacol 2012 0.89
23 Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion. J Biol Chem 2011 0.87
24 Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes. Biochem J 2003 0.87
25 Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells. PLoS One 2010 0.87
26 Adipose tissue-specific dysregulation of angiotensinogen by oxidative stress in obesity. Metabolism 2010 0.85
27 Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis. Sci Signal 2012 0.83
28 Skp2 promotes adipocyte differentiation via a p27Kip1-independent mechanism in primary mouse embryonic fibroblasts. Biochem Biophys Res Commun 2008 0.79
29 The Krüppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes. Biochem Biophys Res Commun 2008 0.79
30 Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing angiogenesis. Mol Endocrinol 2011 0.78
31 Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects. Eur J Pharmacol 2012 0.78
32 Membrane topology of murine glycerol-3-phosphate acyltransferase 2. Biochem Biophys Res Commun 2012 0.78
33 Intracerebroventricular injection of adiponectin regulates locomotor activity in rats. J Med Invest 2015 0.77
34 Excessive dietary phosphorus intake impairs endothelial function in young healthy men: a time- and dose-dependent study. J Med Invest 2015 0.77
35 Fused protein of deltaPKC activation loop and PDK1-interacting fragment (deltaAL-PIF) functions as a pseudosubstrate and an inhibitory molecule for PDK1 when expressed in cells. Genes Cells 2006 0.77
36 Severe catabolic state after an overnight fast in patients with chronic renal failure. Nutrition 2010 0.77
37 Vimentin binds IRAP and is involved in GLUT4 vesicle trafficking. Biochem Biophys Res Commun 2011 0.77
38 Identification and functional characterization of human glycerol-3-phosphate acyltransferase 1 gene promoters. Biochem Biophys Res Commun 2012 0.76
39 High density lipoprotein inhibits the activation of sterol regulatory element-binding protein-1 in cultured cells. FEBS Lett 2010 0.75
40 Cysteine string protein 1 (CSP1) modulates insulin sensitivity by attenuating glucose transporter 4 (GLUT4) vesicle docking with the plasma membrane. J Med Invest 2013 0.75
41 A novel lipoprotein (a) lowering drug, D-47, decreases neointima thickening after vascular injury. J Med Invest 2017 0.75
42 [The regulatory mechanism (s) of adipocyte differentiation and proliferation]. Nihon Rinsho 2006 0.75
43 [Preface]. Clin Calcium 2016 0.75
44 [Disorder of carbohydrate metabolism]. Nihon Rinsho 2004 0.75