Published in Magn Reson Med on March 01, 2009
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature (2011) 2.47
Theory, instrumentation, and applications of electron paramagnetic resonance oximetry. Chem Rev (2010) 1.48
A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment. Integr Biol (Camb) (2011) 1.24
Dynamic changes in oxygenation of intracranial tumor and contralateral brain during tumor growth and carbogen breathing: a multisite EPR oximetry with implantable resonators. J Magn Reson (2011) 1.11
In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI. Magn Reson Med (2010) 1.10
Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer. Chem Rev (2010) 1.06
Hypoxic stress and cancer: imaging the axis of evil in tumor metastasis. NMR Biomed (2011) 1.06
New frontiers and developing applications in 19F NMR. Prog Nucl Magn Reson Spectrosc (2012) 1.02
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Multimodality imaging of hypoxia in preclinical settings. Q J Nucl Med Mol Imaging (2010) 0.98
Principal component analysis enhances SNR for dynamic electron paramagnetic resonance oxygen imaging of cycling hypoxia in vivo. Magn Reson Med (2013) 0.97
Monitoring of hemodynamic changes induced in the healthy breast through inspired gas stimuli with MR-guided diffuse optical imaging. Med Phys (2010) 0.94
Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy. Front Pharmacol (2012) 0.88
In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome. Int J Radiat Oncol Biol Phys (2011) 0.85
Functional electron paramagnetic resonance imaging of ischemic rat heart: Monitoring of tissue oxygenation and pH. Magn Reson Med (2015) 0.83
Quantitative tissue oxygen measurement in multiple organs using 19F MRI in a rat model. Magn Reson Med (2011) 0.81
Assessing intrarenal nonperfusion and vascular leakage in acute kidney injury with multinuclear (1) H/(19) F MRI and perfluorocarbon nanoparticles. Magn Reson Med (2013) 0.80
An oxygen-consuming phantom simulating perfused tissue to explore oxygen dynamics and (19)F MRI oximetry. MAGMA (2010) 0.80
Mapping in vivo tumor oxygenation within viable tumor by 19F-MRI and multispectral analysis. Neoplasia (2013) 0.78
Perfluorocarbon nanoparticles for physiological and molecular imaging and therapy. Adv Chronic Kidney Dis (2013) 0.77
Assessing Tumor Oxygenation for Predicting Outcome in Radiation Oncology: A Review of Studies Correlating Tumor Hypoxic Status and Outcome in the Preclinical and Clinical Settings. Front Oncol (2017) 0.75
Monitoring and Targeting Anti-VEGF Induced Hypoxia within the Viable Tumor by (19)F-MRI and Multispectral Analysis. Neoplasia (2017) 0.75
In vivo electron paramagnetic resonance oximetry and applications in the brain. Med Gas Res (2017) 0.75
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest (2008) 7.52
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet (2008) 3.94
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature (2011) 2.47
Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment. Clin Cancer Res (2005) 1.65
How does blood oxygen level-dependent (BOLD) contrast correlate with oxygen partial pressure (pO2) inside tumors? Magn Reson Med (2002) 1.60
Glucocorticoids modulate tumor radiation response through a decrease in tumor oxygen consumption. Clin Cancer Res (2007) 1.57
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. PLoS One (2012) 1.53
Comparison of a reference region model with direct measurement of an AIF in the analysis of DCE-MRI data. Magn Reson Med (2007) 1.49
Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia? Phys Med Biol (2004) 1.22
Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury. Gastroenterology (2009) 1.18
Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions. Int J Radiat Oncol Biol Phys (2005) 1.15
Electron paramagnetic resonance as a tool to evaluate human ovarian tissue reoxygenation after xenografting. Fertil Steril (2008) 1.13
Comparison of methods for measuring oxygen consumption in tumor cells in vitro. Anal Biochem (2009) 1.13
Caveolin-1 is critical for the maturation of tumor blood vessels through the regulation of both endothelial tube formation and mural cell recruitment. Am J Pathol (2007) 1.11
Potentiation of cyclophosphamide chemotherapy using the anti-angiogenic drug thalidomide: importance of optimal scheduling to exploit the 'normalization' window of the tumor vasculature. Cancer Lett (2006) 1.11
The role of vessel maturation and vessel functionality in spontaneous fluctuations of T2*-weighted GRE signal within tumors. NMR Biomed (2006) 1.09
Implantable resonators--a technique for repeated measurement of oxygen at multiple deep sites with in vivo EPR. Adv Exp Med Biol (2010) 1.08
In vivo EPR: when, how and why? NMR Biomed (2004) 1.06
Effect of anesthesia on the signal intensity in tumors using BOLD-MRI: comparison with flow measurements by Laser Doppler flowmetry and oxygen measurements by luminescence-based probes. Magn Reson Imaging (2004) 1.06
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment. Proc Natl Acad Sci U S A (2010) 1.05
Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1. J Neurosci (2010) 1.05
Modulation of the tumor vasculature functionality by ionizing radiation accounts for tumor radiosensitization and promotes gene delivery. FASEB J (2002) 1.03
New insight into the "depth of cure" of dimethacrylate-based dental composites. Dent Mater (2012) 1.02
Dietary fructans, but not cellulose, decrease triglyceride accumulation in the liver of obese Zucker fa/fa rats. J Nutr (2002) 1.01
A phosphonated triarylmethyl radical as a probe for measurement of pH by EPR. Chem Commun (Camb) (2012) 1.00
Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis. Cardiovasc Res (2008) 0.99
Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study. Free Radic Res (2005) 0.98
In vivo detection of inflammation using pegylated iron oxide particles targeted at E-selectin: a multimodal approach using MR imaging and EPR spectroscopy. Invest Radiol (2009) 0.97
Sensitivity of whole human teeth to fast neutrons and gamma-rays estimated by L-band EPR spectroscopy. Radiat Meas (2002) 0.96
Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments. FEBS J (2008) 0.96
In vivo selection of biocompatible alginates for islet encapsulation and subcutaneous transplantation. Tissue Eng Part A (2010) 0.96
Decrease in tumor cell oxygen consumption after treatment with vandetanib (ZACTIMA; ZD6474) and its effect on response to radiotherapy. Radiat Res (2009) 0.96
Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy. Cancer Res (2006) 0.95
Arsenic trioxide treatment decreases the oxygen consumption rate of tumor cells and radiosensitizes solid tumors. Cancer Res (2011) 0.95
Tumor radiosensitization by antiinflammatory drugs: evidence for a new mechanism involving the oxygen effect. Cancer Res (2005) 0.95
Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells. Arterioscler Thromb Vasc Biol (2011) 0.94
Nitric oxide delivery to cancer: why and how? Eur J Cancer (2009) 0.93
Determination of the maturity and functionality of tumor vasculature by MRI: correlation between BOLD-MRI and DCE-MRI using P792 in experimental fibrosarcoma tumors. Magn Reson Med (2006) 0.93
Mapping of oxygen by imaging lipids relaxation enhancement: a potential sensitive endogenous MRI contrast to map variations in tissue oxygenation. Magn Reson Med (2012) 0.93
Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption. Cancer Res (2002) 0.92
Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment. Cancer Res (2004) 0.92
Botulinum toxin potentiates cancer radiotherapy and chemotherapy. Clin Cancer Res (2006) 0.92
Synthesis of two persistent fluorinated tetrathiatriarylmethyl (TAM) radicals for biomedical EPR applications. Bioorg Med Chem Lett (2008) 0.91
Development and evaluation of biocompatible inks for the local measurement of oxygen using in vivo EPR. NMR Biomed (2004) 0.91
The impact of hyperglycemia and the presence of encapsulated islets on oxygenation within a bioartificial pancreas in the presence of mesenchymal stem cells in a diabetic Wistar rat model. Biomaterials (2011) 0.90
Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery. Mol Cancer Ther (2006) 0.90
Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: a comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry. Radiother Oncol (2012) 0.89
Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study. Invest New Drugs (2010) 0.89
The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action. BMC Cancer (2012) 0.89
The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome. FASEB J (2013) 0.88
Chiral properties of tetrathiatriarylmethyl spin probes. Chem Commun (Camb) (2011) 0.87
Nitrosylated hemoglobin levels in human venous erythrocytes correlate with vascular endothelial function measured by digital reactive hyperemia. PLoS One (2013) 0.87
Antibody-functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of 89Zr-labeled cetuximab in mice. Contrast Media Mol Imaging (2013) 0.87
Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing. Int J Radiat Oncol Biol Phys (2010) 0.87
Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. PLoS One (2011) 0.86
Autologous Adipose Stromal Cells Seeded onto a Human Collagen Matrix for Dermal Regeneration in Chronic Wounds: Clinical Proof of Concept. Plast Reconstr Surg (2015) 0.86
Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors. Radiother Oncol (2008) 0.86
Complex relationship between changes in oxygenation status and changes in R*2: the case of insulin and NS-398, two inhibitors of oxygen consumption. Magn Reson Med (2006) 0.86
Cluster analysis of BOLD fMRI time series in tumors to study the heterogeneity of hemodynamic response to treatment. Magn Reson Med (2003) 0.85
Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif. PLoS One (2012) 0.85
Captopril and S-nitrosocaptopril as potent radiosensitizers: Comparative study and underlying mechanisms. Cancer Lett (2010) 0.85
Use of botulinum toxins in cancer therapy. Expert Opin Investig Drugs (2007) 0.85
Tellurite-induced oxidative stress leads to cell death of murine hepatocarcinoma cells. Biometals (2010) 0.84
Hexafluorobenzene in comparison with perfluoro-15-crown-5-ether for repeated monitoring of oxygenation using 19F MRI in a mouse model. Magn Reson Med (2012) 0.84
Irradiation promotes Akt-targeting therapeutic gene delivery to the tumor vasculature. Int J Radiat Oncol Biol Phys (2007) 0.83
Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses. Int J Radiat Oncol Biol Phys (2003) 0.83
Improvement of subcutaneous bioartificial pancreas vascularization and function by coencapsulation of pig islets and mesenchymal stem cells in primates. Cell Transplant (2013) 0.83
Contribution of oxygenation to BOLD contrast in exercising muscle. Magn Reson Med (2004) 0.83
Enhanced expression of the high affinity glutamate transporter GLT-1 in C6 glioma cells delays tumour progression in rat. Exp Neurol (2009) 0.83
In vivo mapping of tumor oxygen consumption using (19)F MRI relaxometry. NMR Biomed (2010) 0.83
Assessment of liver phagocytic activity using EPR spectrometry and imaging. Magn Reson Imaging (2008) 0.82
Determination of the venous output function from MR signal phase: feasibility for quantitative DCE-MRI in human brain. Magn Reson Med (2010) 0.82
A New EPR oximetry protocol to estimate the tissue oxygen consumption in vivo. Radiat Res (2009) 0.82
Influence of free radicals signal from dental resins on the radio-induced signal in teeth in EPR retrospective dosimetry. PLoS One (2013) 0.82
Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption. Int J Cancer (2004) 0.82
Variability of Mouse Left Ventricular Function Assessment by 11.7 Tesla MRI. J Cardiovasc Transl Res (2015) 0.82
Vascular caveolin deficiency supports the angiogenic effects of nitrite, a major end product of nitric oxide metabolism in tumors. Mol Cancer Res (2009) 0.81
Changes in the tumor microenvironment during low-dose-rate permanent seed implantation iodine-125 brachytherapy. Int J Radiat Oncol Biol Phys (2005) 0.81
Hydroxyl radical release from dental resins: electron paramagnetic resonance evidence. Acta Biomater (2010) 0.80
Multimodal imaging of tumor response to sorafenib combined with radiation therapy: comparison between diffusion-weighted MRI, choline spectroscopy and 18F-FLT PET imaging. Contrast Media Mol Imaging (2013) 0.80
The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy. Clin Cancer Res (2008) 0.80
Surrogate MR markers of response to chemo- or radiotherapy in association with co-treatments: a retrospective analysis of multi-modal studies. Contrast Media Mol Imaging (2010) 0.80
Carbon blacks as EPR sensors for localized measurements of tissue oxygenation. Magn Reson Med (2004) 0.80
Hypoxia is not required for human endometrial breakdown or repair in a xenograft model of menstruation. FASEB J (2013) 0.80
Potentiation of radiation-induced regrowth delay by isosorbide dinitrate in FSaII murine tumors. Int J Cancer (2003) 0.80
Evaluation of the dose distribution gradient in the close vicinity of brachytherapy seeds using electron paramagnetic resonance imaging. Magn Reson Med (2009) 0.79
Influence of cell detachment on the respiration rate of tumor and endothelial cells. PLoS One (2013) 0.79
Molecular electron paramagnetic resonance imaging of melanin in melanomas: a proof-of-concept. NMR Biomed (2008) 0.79
The contribution of electron paramagnetic resonance to melanoma research. J Skin Cancer (2011) 0.78
Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence. Contrast Media Mol Imaging (2014) 0.78
Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging. Contrast Media Mol Imaging (2011) 0.78
Tumor reoxygenation following administration of the EGFR inhibitor, gefitinib, in experimental tumors. Adv Exp Med Biol (2013) 0.78
Use of Xanthinol Nicotinate as a co-treatment for radio- and chemo-therapy in experimental tumors. Int J Cancer (2010) 0.78
19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy. Magn Reson Med (2008) 0.78
Electron paramagnetic resonance highlights that the oxygen effect contributes to the radiosensitizing effect of paclitaxel. PLoS One (2012) 0.78
In vivo colocalization of 2-nitroimidazole EF5 fluorescence intensity and electron paramagnetic resonance oximetry in mouse tumors. Radiother Oncol (2003) 0.77