PubRank

Nicolas G Bazan

Author PubWeight™ 135.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc Natl Acad Sci U S A 2004 4.28
2 Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J Biol Chem 2003 3.80
3 A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest 2005 3.44
4 Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 2002 3.15
5 Sleep deprivation causes behavioral, synaptic, and membrane excitability alterations in hippocampal neurons. J Neurosci 2003 2.19
6 Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling. Proc Natl Acad Sci U S A 2007 1.96
7 DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN. J Am Soc Nephrol 2012 1.93
8 Novel proresolving aspirin-triggered DHA pathway. Chem Biol 2011 1.93
9 Robust docosahexaenoic acid-mediated neuroprotection in a rat model of transient, focal cerebral ischemia. Stroke 2009 1.62
10 Opposing crosstalk between leptin and glucocorticoids rapidly modulates synaptic excitation via endocannabinoid release. J Neurosci 2006 1.62
11 Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity. J Neurophysiol 2002 1.58
12 Synthesis and in vivo evaluation of non-hepatotoxic acetaminophen analogs. Bioorg Med Chem 2006 1.55
13 Postsynaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor. J Neurosci 2005 1.52
14 Rapid glucocorticoid-mediated endocannabinoid release and opposing regulation of glutamate and gamma-aminobutyric acid inputs to hypothalamic magnocellular neurons. Endocrinology 2005 1.51
15 Docosahexaenoic acid complexed to albumin elicits high-grade ischemic neuroprotection. Stroke 2004 1.47
16 Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models. PLoS One 2011 1.45
17 Photoreceptor outer segment phagocytosis attenuates oxidative stress-induced apoptosis with concomitant neuroprotectin D1 synthesis. Proc Natl Acad Sci U S A 2007 1.38
18 Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1. J Biol Chem 2009 1.34
19 Mapping the entire human corneal nerve architecture. Exp Eye Res 2010 1.31
20 Topical combination of NGF and DHA increases rabbit corneal nerve regeneration after photorefractive keratectomy. Invest Ophthalmol Vis Sci 2005 1.30
21 Coordinate activation of HIF-1 and NF-kappaB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia. Invest Ophthalmol Vis Sci 2003 1.28
22 Activity-dependent release and actions of endocannabinoids in the rat hypothalamic supraoptic nucleus. J Physiol 2005 1.26
23 Docosahexaenoic Acid therapy of experimental ischemic stroke. Transl Stroke Res 2010 1.26
24 Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils. Prostaglandins Leukot Essent Fatty Acids 2010 1.26
25 Sleep deprivation-induced alterations in excitatory synaptic transmission in the CA1 region of the rat hippocampus. J Physiol 2005 1.25
26 Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons. J Neurophysiol 2005 1.22
27 Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism. J Biol Chem 2002 1.22
28 Docosahexaenoic acid and the aging brain. J Nutr 2008 1.20
29 Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA. Invest Ophthalmol Vis Sci 2009 1.20
30 Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness. Nat Med 2013 1.20
31 Systemic fatty acid responses to transient focal cerebral ischemia: influence of neuroprotectant therapy with human albumin. J Neurochem 2002 1.18
32 Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways. Br J Pharmacol 2002 1.17
33 Docosahexaenoic acid signaling modulates cell survival in experimental ischemic stroke penumbra and initiates long-term repair in young and aged rats. PLoS One 2012 1.14
34 Lipid signaling: sleep, synaptic plasticity, and neuroprotection. Prostaglandins Other Lipid Mediat 2005 1.13
35 Post-training cyclooxygenase-2 (COX-2) inhibition impairs memory consolidation. Learn Mem 2002 1.13
36 Altered NMDA receptor trafficking contributes to sleep deprivation-induced hippocampal synaptic and cognitive impairments. Biochem Biophys Res Commun 2005 1.11
37 Simplified lentivirus vector production in protein-free media using polyethylenimine-mediated transfection. J Virol Methods 2009 1.10
38 DNA damage and repair in light-induced photoreceptor degeneration. Invest Ophthalmol Vis Sci 2002 1.10
39 Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity. Mol Vis 2004 1.09
40 A comparative analysis of constitutive and cell-specific promoters in the adult mouse hippocampus using lentivirus vector-mediated gene transfer. J Gene Med 2008 1.09
41 Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria. Exp Eye Res 2005 1.08
42 Spatial correlation of mouse photoreceptor-RPE thickness between SD-OCT and histology. Exp Eye Res 2010 1.07
43 Sleep deprivation impairs hippocampus-mediated contextual learning but not amygdala-mediated cued learning in rats. Eur J Neurosci 2004 1.07
44 Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse. Mol Vis 2010 1.06
45 Omega-3 essential fatty acids modulate initiation and progression of neurodegenerative disease. Mol Neurobiol 2010 1.05
46 Inflammatory, apoptotic, and survival gene signaling in Alzheimer's disease. A review on the bioactivity of neuroprotectin D1 and apoptosis. Mol Neurobiol 2010 1.04
47 Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival. J Biol Chem 2010 1.03
48 Hippocampal kindling epileptogenesis upregulates neuronal cyclooxygenase-2 expression in neocortex. Exp Neurol 2003 1.03
49 PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis. Exp Eye Res 2010 1.02
50 Activation of platelet-activating factor receptor-coupled G alpha q leads to stimulation of Src and focal adhesion kinase via two separate pathways in human umbilical vein endothelial cells. J Biol Chem 2003 1.02
51 Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein. J Neurosci 2013 1.02
52 Cyclooxygenase-3 gene expression in Alzheimer hippocampus and in stressed human neural cells. Neurochem Res 2004 0.99
53 Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery. Invest Ophthalmol Vis Sci 2013 0.99
54 Platelet-activating factor receptor-deficient mice are protected from experimental sleep apnea-induced learning deficits. J Neurochem 2004 0.99
55 Recovery of corneal sensitivity, calcitonin gene-related peptide-positive nerves, and increased wound healing induced by pigment epithelial-derived factor plus docosahexaenoic acid after experimental surgery. Arch Ophthalmol 2011 0.98
56 Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection. J Neurosci 2011 0.98
57 Alkali-induced corneal stromal melting prevention by a novel platelet-activating factor receptor antagonist. Arch Ophthalmol 2006 0.97
58 Differential induction of c-Jun and Fos-like proteins in rat hippocampus and dorsal striatum after training in two water maze tasks. Neurobiol Learn Mem 2005 0.97
59 Epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase Calpha translocation to the plasma membrane through 15(S)-hydroxyeicosatetraenoic acid synthesis. J Biol Chem 2004 0.96
60 Ataxin-1 poly(Q)-induced proteotoxic stress and apoptosis are attenuated in neural cells by docosahexaenoic acid-derived neuroprotectin D1. J Biol Chem 2012 0.96
61 VEGF-mediated endothelial P-selectin translocation: role of VEGF receptors and endogenous PAF synthesis. Blood 2004 0.96
62 Identification of intracellular phospholipases A2 in the human eye: involvement in phagocytosis of photoreceptor outer segments. Invest Ophthalmol Vis Sci 2007 0.96
63 Docosahexaenoic acid neurolipidomics. Prostaglandins Other Lipid Mediat 2009 0.95
64 Cellular and 3D optical coherence tomography assessment during the initiation and progression of retinal degeneration in the Ccl2/Cx3cr1-deficient mouse. Exp Eye Res 2011 0.95
65 EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation. Invest Ophthalmol Vis Sci 2011 0.94
66 Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP). J Biol Chem 2013 0.93
67 Diacylglycerol kinase epsilon modulates rapid kindling epileptogenesis. Epilepsia 2006 0.92
68 Comparative in vivo high-resolution confocal microscopy of corneal epithelium, sub-basal nerves and stromal cells in mice with and without dry eye after photorefractive keratectomy. Clin Experiment Ophthalmol 2007 0.92
69 Glutamate signalling and secretory phospholipase A2 modulate the release of arachidonic acid from neuronal membranes. J Neurosci Res 2002 0.92
70 The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis. Epilepsia 2011 0.90
71 Wound-healing response and refractive regression after conductive keratoplasty. J Cataract Refract Surg 2006 0.90
72 Platelet-activating factor (PAF) induces activation of matrix metalloproteinase 2 activity and vascular endothelial cell invasion and migration. FASEB J 2004 0.90
73 Heterogeneous expression and regulation of hippocampal prostaglandin E2 receptors. J Neurosci Res 2005 0.90
74 Eliminating the adrenal stress response does not affect sleep deprivation-induced acquisition deficits in the water maze. Life Sci 2005 0.89
75 Platelet-activating factor (PAF) induces corneal neovascularization and upregulates VEGF expression in endothelial cells. Invest Ophthalmol Vis Sci 2004 0.89
76 Deafness and retinal degeneration in a novel USH1C knock-in mouse model. Dev Neurobiol 2010 0.89
77 Platelet activating factor-induced neuronal apoptosis is initiated independently of its G-protein coupled PAF receptor and is inhibited by the benzoate orsellinic acid. J Neurochem 2007 0.89
78 c-Jun N-terminal kinase activation responses induced by hippocampal kindling are mediated by reactive astrocytes. J Neurosci 2006 0.89
79 Neuroprotectin D1 induces neuronal survival and downregulation of amyloidogenic processing in Alzheimer's disease cellular models. Mol Neurobiol 2011 0.88
80 Stereocontrolled total synthesis of neuroprotectin D1 / protectin D1 and its aspirin-triggered stereoisomer. Tetrahedron Lett 2012 0.88
81 Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture. Neurosci Lett 2003 0.88
82 Omega-3 fatty acid docosahexaenoic acid is the precursor of neuroprotectin D1 in the nervous system. World Rev Nutr Diet 2009 0.88
83 Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase. J Neurosci 2013 0.87
84 Prevention of experimental diffuse lamellar keratitis using a novel platelet-activating factor receptor antagonist. J Cataract Refract Surg 2004 0.87
85 Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism. Cell Mol Neurobiol 2005 0.87
86 Microglial ramification and redistribution concomitant with the attenuation of choroidal neovascularization by neuroprotectin D1. Mol Vis 2013 0.87
87 Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondria. J Neurosci Res 2002 0.86
88 Neuroprotectin D1 modulates the induction of pro-inflammatory signaling and promotes retinal pigment epithelial cell survival during oxidative stress. Adv Exp Med Biol 2010 0.86
89 Docosahexaenoic acid complexed to human albumin in experimental stroke: neuroprotective efficacy with a wide therapeutic window. Exp Transl Stroke Med 2012 0.86
90 Spatial organization of lipids in the human retina and optic nerve by MALDI imaging mass spectrometry. J Lipid Res 2013 0.85
91 Comparison of corneal wound-healing response in photorefractive keratectomy and laser-assisted subepithelial keratectomy. J Cataract Refract Surg 2005 0.85
92 Acute treatment with docosahexaenoic acid complexed to albumin reduces injury after a permanent focal cerebral ischemia in rats. PLoS One 2013 0.85
93 Interplay among platelet-activating factor, oxidative stress, and group I metabotropic glutamate receptors modulates neuronal survival. J Neurosci Res 2004 0.85
94 A2E selectively induces cox-2 in ARPE-19 and human neural cells. Curr Eye Res 2006 0.84
95 Secretory phospholipase A2-mediated neuronal cell death involves glutamate ionotropic receptors. Neuroreport 2002 0.83
96 Lipid signaling in experimental epilepsy. Neurochem Res 2005 0.83
97 Epileptogenesis in diacylglycerol kinase epsilon deficiency up-regulates COX-2 and tyrosine hydroxylase in hippocampus. Biochem Biophys Res Commun 2005 0.83
98 N-3 fatty acid rich triglyceride emulsions are neuroprotective after cerebral hypoxic-ischemic injury in neonatal mice. PLoS One 2013 0.83
99 LAU-0901, a novel platelet-activating factor receptor antagonist, confers enduring neuroprotection in experimental focal cerebral ischemia in the rat. Brain Res 2008 0.82
100 Secreted phospholipase A2 potentiates glutamate-induced calcium increase and cell death in primary neuronal cultures. J Neurosci Res 2002 0.82
101 Characterization and location of secretory phospholipase A2 groups IIE, V, and X in the rat brain. J Neurosci Res 2006 0.82
102 Mediator lipidomics in ophthalmology: targets for modulation in inflammation, neuroprotection and nerve regeneration. Curr Eye Res 2013 0.82
103 LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia. Exp Neurol 2008 0.81
104 Human secretory phospholipase A(2), group IB in normal eyes and in eye diseases. Acta Ophthalmol Scand 2007 0.81
105 NPD1 induction of retinal pigment epithelial cell survival involves PI3K/Akt phosphorylation signaling. Neurochem Res 2010 0.81
106 Inhibition of Myosin light-chain kinase attenuates cerebral edema after traumatic brain injury in postnatal mice. J Neurotrauma 2013 0.80
107 A novel platelet activating factor receptor antagonist reduces cell infiltration and expression of inflammatory mediators in mice exposed to desiccating conditions after PRK. Clin Dev Immunol 2009 0.80
108 Aspirin-triggered lipoxin A4 (15-epi-LXA4) increases the endothelial viability of human corneas storage in Optisol-GS. J Ocul Pharmacol Ther 2011 0.80
109 Lipid-mediated cell signaling protects against injury and neurodegeneration. J Nutr 2010 0.80
110 Light-induced photoreceptor damage triggers DNA repair: differential fate of rods and cones. Adv Exp Med Biol 2003 0.80
111 Neuroprotection by platelet-activating factor antagonism. Ann N Y Acad Sci 2005 0.80
112 Selective relocalization and proteasomal downregulation of PKCalpha induced by platelet-activating factor in retinal pigment epithelium. Invest Ophthalmol Vis Sci 2006 0.80
113 Expression and location of mRNAs encoding multiple forms of secretory phospholipase A2 in the rat retina. J Neurosci Res 2004 0.79
114 Medicine: lipid signals in pain control. Nature 2002 0.79
115 Expression and induction of secretory phospholipase A2 group IB in brain. Cell Mol Neurobiol 2005 0.79
116 Use of autologous serum in corneal epithelial defects post-lamellar surgery. Cornea 2005 0.79
117 DNA repair in photoreceptor survival. Mol Neurobiol 2003 0.79
118 Superior Neuroprotective Efficacy of LAU-0901, a Novel Platelet-Activating Factor Antagonist, in Experimental Stroke. Transl Stroke Res 2011 0.78
119 Secretory phospholipase A(2) induces delayed neuronal COX-2 expression compared with glutamate. J Neurosci Res 2002 0.78
120 Budesonide epimer R, LAU-8080 and phenyl butyl nitrone synergistically repress cyclooxygenase-2 induction in [IL-1beta+Abeta42]-stressed human neural cells. Neurosci Lett 2005 0.78
121 Acetaminophen modifies hippocampal synaptic plasticity via a presynaptic 5-HT2 receptor. Neuroreport 2003 0.78
122 Effects of hyperglycemia and hypercapnia on lipid metabolism during complete brain ischemia. Brain Res 2004 0.77
123 Juana María Pasquini: a role model for young neurochemists. Neurochem Res 2002 0.75
124 Corrigendum: Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism. Sci Rep 2016 0.75
125 Elovanoid-N32 or RvD6-isomer decrease ACE2 and binding of S protein RBD after injury or INFγ in the eye. Res Sq 2020 0.75
126 Agrin downregulation induced by nerve injury contributes to neuropathic pain. J Neurosci 2010 0.75
127 Corrigendum: Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival. Nat Commun 2015 0.75
128 Stereoselective Total Synthesis of Macrophage-produced Prohealing 14,21-Dihydroxydocosahexaenoic Acids. J Org Chem 2017 0.75