Longitudinal prognostic value of serum "free" copper in patients with Alzheimer disease.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMID 19122030)

Published in Neurology on January 06, 2009

Authors

R Squitti1, F Bressi, P Pasqualetti, C Bonomini, R Ghidoni, G Binetti, E Cassetta, F Moffa, M Ventriglia, F Vernieri, P M Rossini

Author Affiliations

1: Department of Neuroscience, AFaR-Osp. Fatebenefratelli, 00186, Rome, Italy. rosanna.squitti@afar.it

Associated clinical trials:

Trial of Novel Oral Zinc Cysteine Preparation in Alzheimer's Disease | NCT01099332

Articles citing this

Copper-2 Ingestion, Plus Increased Meat Eating Leading to Increased Copper Absorption, Are Major Factors Behind the Current Epidemic of Alzheimer's Disease. Nutrients (2015) 1.79

Wilson's disease and other neurological copper disorders. Lancet Neurol (2015) 1.53

Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. PLoS One (2011) 1.32

Copper: toxicological relevance and mechanisms. Arch Toxicol (2014) 0.90

Association between the c. 2495 A>G ATP7B Polymorphism and Sporadic Alzheimer's Disease. Int J Alzheimers Dis (2011) 0.90

Interactions of metals and Apolipoprotein E in Alzheimer's disease. Front Aging Neurosci (2014) 0.88

Linkage disequilibrium and haplotype analysis of the ATP7B gene in Alzheimer's disease. Rejuvenation Res (2013) 0.84

Zinc deficiency and zinc therapy efficacy with reduction of serum free copper in Alzheimer's disease. Int J Alzheimers Dis (2013) 0.84

Issues raised involving the copper hypotheses in the causation of Alzheimer's disease. Int J Alzheimers Dis (2011) 0.82

Role of copper and cholesterol association in the neurodegenerative process. Int J Alzheimers Dis (2013) 0.82

Importance and management of micronutrient deficiencies in patients with Alzheimer's disease. Clin Interv Aging (2013) 0.81

Alzheimer's disease causation by copper toxicity and treatment with zinc. Front Aging Neurosci (2014) 0.81

Decreased copper in Alzheimer's disease brain is predominantly in the soluble extractable fraction. Int J Alzheimers Dis (2013) 0.80

Paradigm shift in treatment of Alzheimer's disease: zinc therapy now a conscientious choice for care of individual patients. Int J Alzheimers Dis (2011) 0.80

Regulation of copper transport crossing brain barrier systems by Cu-ATPases: effect of manganese exposure. Toxicol Sci (2014) 0.79

Ceruloplasmin and iron in Alzheimer's disease and Parkinson's disease: a synopsis of recent studies. Neuropsychiatr Dis Treat (2012) 0.78

Acute phase proteins are major clients for the chaperone action of α₂-macroglobulin in human plasma. Cell Stress Chaperones (2012) 0.78

Altered serum iron and copper homeostasis predicts cognitive decline in mild cognitive impairment. J Alzheimers Dis (2012) 0.78

Diabetes and Alzheimer's Disease: Can Elevated Free Copper Predict the Risk of the Disease? J Alzheimers Dis (2016) 0.77

Effects of Copper and/or Cholesterol Overload on Mitochondrial Function in a Rat Model of Incipient Neurodegeneration. Int J Alzheimers Dis (2013) 0.76

The Effects of Copper and Copper Blocking Agents on Gill Mitochondrial O(2) Utilization of Crassostrea virginica. In Vivo (Brooklyn) (2010) 0.75

Potential fluid biomarkers for pathological brain changes in Alzheimer's disease: Implication for the screening of cognitive frailty. Mol Med Rep (2016) 0.75

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine. Front Aging Neurosci (2014) 0.75

Articles by these authors

A comparison of injections of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure. N Engl J Med (1999) 3.69

A comparison of botulinum toxin and saline for the treatment of chronic anal fissure. N Engl J Med (1998) 3.19

Impaired cerebral vasoreactivity and risk of stroke in patients with asymptomatic carotid artery stenosis. JAMA (2000) 3.06

Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ (2008) 2.89

A practical guide to diagnostic transcranial magnetic stimulation: report of an IFCN committee. Clin Neurophysiol (2012) 2.60

Estimation of the cortical functional connectivity with the multimodal integration of high-resolution EEG and fMRI data by directed transfer function. Neuroimage (2005) 2.06

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration. Neurology (2008) 1.98

Elevation of serum copper levels in Alzheimer's disease. Neurology (2002) 1.93

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers. Neurology (2010) 1.93

Excess of serum copper not related to ceruloplasmin in Alzheimer disease. Neurology (2005) 1.86

Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease. FASEB J (1998) 1.86

Outcome of carotid artery occlusion is predicted by cerebrovascular reactivity. Stroke (1999) 1.84

Carotid artery intima-media thickness and lacunar versus nonlacunar infarcts. Stroke (2002) 1.78

The role of the left frontal lobe in action naming: rTMS evidence. Neurology (2002) 1.73

Object and action naming in Alzheimer's disease and frontotemporal dementia [see comment]. Neurology (1998) 1.71

Characterization of a glycosphingolipid antigen defined by the monoclonal antibody MBr1 expressed in normal and neoplastic epithelial cells of human mammary gland. J Biol Chem (1984) 1.70

Vernal keratoconjunctivitis revisited: a case series of 195 patients with long-term followup. Ophthalmology (2000) 1.68

Multiperspective follow-up of untreated carpal tunnel syndrome: a multicenter study. Neurology (2001) 1.68

Mapping of motor cortical reorganization after stroke. A brain stimulation study with focal magnetic pulses. Stroke (1997) 1.62

High prevalence of pathogenic mutations in patients with early-onset dementia detected by sequence analyses of four different genes. Am J Hum Genet (2000) 1.61

Botulinum toxin for chronic anal fissure. Lancet (1994) 1.61

Mini-Mental State Examination: a normative study in Italian elderly population. Eur J Neurol (1996) 1.60

Calcium responses in human fibroblasts: a diagnostic molecular profile for Alzheimer's disease. Neurobiol Aging (1996) 1.59

Analysis of blink rate patterns in normal subjects. Mov Disord (1997) 1.57

Nervous propagation along 'central' motor pathways in intact man: characteristics of motor responses to 'bifocal' and 'unifocal' spine and scalp non-invasive stimulation. Electroencephalogr Clin Neurophysiol (1985) 1.56

Human movement-related potentials vs desynchronization of EEG alpha rhythm: a high-resolution EEG study. Neuroimage (1999) 1.54

Maternal total vascular resistance and concentric geometry: a key to identify uncomplicated gestational hypertension. BJOG (2006) 1.50

Decreased sympathetic inhibition in gastroesophageal reflux disease. Clin Auton Res (2001) 1.49

The effect of deep brain stimulation on the frontal N30 component of somatosensory evoked potentials in advanced Parkinson's disease patients. Clin Neurophysiol (1999) 1.47

Recommendations for the clinical use of somatosensory-evoked potentials. Clin Neurophysiol (2008) 1.47

Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease. Mol Psychiatry (2002) 1.45

Gross morphology and morphometric sequelae in the hippocampus, fornix, and corpus callosum of patients with severe non-missile traumatic brain injury without macroscopically detectable lesions: a T1 weighted MRI study. J Neurol Neurosurg Psychiatry (2004) 1.44

Ceramide composition of the psoriatic scale. Biochim Biophys Acta (1993) 1.42

Prefrontal [correction of Prefontal] cortex in long-term memory: an "interference" approach using magnetic stimulation. Nat Neurosci (2001) 1.38

Behavioral syndromes in Alzheimer's disease: description and correlates. Dement Geriatr Cogn Disord (1999) 1.37

Ketamine increases human motor cortex excitability to transcranial magnetic stimulation. J Physiol (2003) 1.35

Medial temporal atrophy but not memory deficit predicts progression to dementia in patients with mild cognitive impairment. J Neurol Neurosurg Psychiatry (2006) 1.34

Preprocedural serum levels of C-reactive protein predict early complications and late restenosis after coronary angioplasty. J Am Coll Cardiol (1999) 1.33

Influence of the supplementary motor area on primary motor cortex excitability during movements triggered by neutral or emotionally unpleasant visual cues. Exp Brain Res (2003) 1.32

Multimodal integration of high-resolution EEG and functional magnetic resonance imaging data: a simulation study. Neuroimage (2003) 1.32

Excess of nonceruloplasmin serum copper in AD correlates with MMSE, CSF [beta]-amyloid, and h-tau. Neurology (2006) 1.31

Does cerebrovascular disease affect the coupling between neuronal activity and local haemodynamics? Brain (2003) 1.31

Nerve impulse propagation along central and peripheral fast conducting motor and sensory pathways in man. Electroencephalogr Clin Neurophysiol (1985) 1.29

Effect of collateral blood flow and cerebral vasomotor reactivity on the outcome of carotid artery occlusion. Stroke (2001) 1.28

Transcranial magnetic stimulation and cortical evoked potentials: a TMS/EEG co-registration study. Clin Neurophysiol (2006) 1.23

Isolation and characterization of a trisialoganglioside from mouse brain, containing 9-O-acetyl-N-acetylneuraminic acid. J Biol Chem (1980) 1.23

Post-stroke reorganization of brain motor output to the hand: a 2-4 month follow-up with focal magnetic transcranial stimulation. Electroencephalogr Clin Neurophysiol (1997) 1.22

Increased cerebral vasomotor reactivity in migraine with aura: an autoregulation disorder? A transcranial Doppler and near-infrared spectroscopy study. Cephalalgia (2008) 1.22

Motor cortex plasticity predicts recovery in acute stroke. Cereb Cortex (2009) 1.21

Corticospinal excitability modulation to hand muscles during movement imagery. Cereb Cortex (1999) 1.19

Assessing cortical functional connectivity by linear inverse estimation and directed transfer function: simulations and application to real data. Clin Neurophysiol (2004) 1.18

Insulin-like growth factor binding protein-3 induces angiogenesis through IGF-I- and SphK1-dependent mechanisms. J Thromb Haemost (2007) 1.16

Follow-up of interhemispheric differences of motor evoked potentials from the 'affected' and 'unaffected' hemispheres in human stroke. Brain Res (1998) 1.16

Abnormality of water barrier function in psoriasis. Role of ceramide fractions. Arch Dermatol (1994) 1.15

Left frontal transcranial magnetic stimulation reduces contralesional extinction in patients with unilateral right brain damage. Brain (1999) 1.15

Cognitive dysfunction in patients with relapsing-remitting multiple sclerosis. Mult Scler (2006) 1.10

High-resolution electro-encephalogram: source estimates of Laplacian-transformed somatosensory-evoked potentials using a realistic subject head model constructed from magnetic resonance images. Med Biol Eng Comput (2000) 1.09

Modulating cortical excitability in acute stroke: a repetitive TMS study. Clin Neurophysiol (2007) 1.09

Clinical applications of motor evoked potentials. Electroencephalogr Clin Neurophysiol (1998) 1.08

Mechanisms of nervous propagation along central motor pathways: noninvasive evaluation in healthy subjects and in patients with neurological disease. Neurosurgery (1987) 1.07

Interhemispheric differences of hand muscle representation in human motor cortex. Muscle Nerve (1997) 1.07

Specific tritium labeling of gangliosides at the 3-position of sphingosines. J Lipid Res (1981) 1.07

Somatosensory processing during movement observation in humans. Clin Neurophysiol (2002) 1.07

Conversion from mild cognitive impairment to Alzheimer's disease is predicted by sources and coherence of brain electroencephalography rhythms. Neuroscience (2006) 1.07

Enhancement of motor cortical excitability in humans by non-invasive electrical stimulation appears prior to voluntary movement. Electroencephalogr Clin Neurophysiol (1988) 1.06

Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Arch Neurol (2000) 1.06

Modulation of motor cortex neuronal networks by rTMS: comparison of local and remote effects of six different protocols of stimulation. J Neurophysiol (2011) 1.06

Cerebral hemodynamics and cognitive performance in patients with asymptomatic carotid stenosis. Neurology (2009) 1.06

Autophagy in term normal human placentas. Placenta (2011) 1.05

Mapping the effect of APOE epsilon4 on gray matter loss in Alzheimer's disease in vivo. Neuroimage (2009) 1.05

Recognition of facial expressions of emotions in school-age children: the intersection of perceptual and semantic categories. Acta Paediatr (2000) 1.05

Neuromagnetic somatosensory homunculus: a non-invasive approach in humans. Neurosci Lett (1991) 1.05

Predictors of mortality and institutionalization in Alzheimer disease patients 1 year after discharge from an Alzheimer dementia unit. Dementia (1995) 1.05

d-penicillamine reduces serum oxidative stress in Alzheimer's disease patients. Eur J Clin Invest (2002) 1.04