M Leal

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosis. J Hepatol 1997 4.08
2 [Prevalence of antibodies against hepatitis C virus in a sample of homosexual males]. Med Clin (Barc) 1993 1.94
3 [Pacemaker implantation in a patient with persistent left superior vena cava and atresia of the right superior vena cava]. Rev Port Cardiol 1994 1.66
4 Drug resistance in patients experiencing early virological failure under a triple combination including indinavir. AIDS 2001 1.56
5 Incidence and risk factors for tuberculosis in HIV-positive subjects by HAART status. Int J Tuberc Lung Dis 2008 1.38
6 Viral envelope protein of HTLV-III is the major target antigen for antibodies in hemophiliac patients. J Infect Dis 1986 1.20
7 Prevalence of and factors associated with visceral leishmaniasis in human immunodeficiency virus type 1-infected patients in southern Spain. J Clin Microbiol 1998 1.17
8 Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain. AIDS 1998 1.14
9 Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries. AIDS 1998 1.14
10 The role of serology in the diagnosis and prognosis of visceral leishmaniasis in patients coinfected with human immunodeficiency virus type-1. Am J Trop Med Hyg 1998 1.13
11 Plasmacytoid dendritic cells reduce HIV production in elite controllers. J Virol 2012 1.09
12 Predictive value of IgM antibodies to hepatitis C virus in patients with chronic hepatitis C undergoing interferon-alpha therapy. Analysis by two different methods. J Viral Hepat 1994 1.08
13 High frequency of serious side effects from meglumine antimoniate given without an upper limit dose for the treatment of visceral leishmaniasis in human immunodeficiency virus type-1-infected patients. Am J Trop Med Hyg 1999 1.03
14 An easy and quick method for the diagnosis of visceral leishmaniasis in HIV-1-infected individuals. AIDS 1993 1.02
15 CD4+ and CD8+ T lymphocyte regeneration after anti-retroviral therapy in HIV-1-infected children and adult patients. Clin Exp Immunol 2000 0.99
16 Intraspecific variation in retinal cone distribution in the bluefin killifish, Lucania goodei. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2003 0.98
17 Unexpected high prevalence of hepatitis C virus genotype 4 in Southern Spain. J Hepatol 1997 0.97
18 Influence of human immunodeficiency virus type 1 infection on the natural course of chronic parenterally acquired hepatitis C. Eur J Clin Microbiol Infect Dis 1995 0.96
19 Hepatitis C virus replication in Caucasian HIV controllers. J Viral Hepat 2011 0.94
20 Hepatitis B virus occult infection in subjects with persistent isolated anti-HBc reactivity. J Hepatol 1993 0.93
21 Thymic volume is associated independently with the magnitude of short- and long-term repopulation of CD4+ T cells in HIV-infected adults after highly active antiretroviral therapy (HAART). Clin Exp Immunol 2004 0.93
22 Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in Spain. The ERASE-2 Study Group. AIDS 2000 0.91
23 Study of the burden on patients with chronic obstructive pulmonary disease. Int J Clin Pract 2009 0.91
24 Consensus conference on chronic viral hepatitis and HIV infection: updated Spanish recommendations. J Viral Hepat 2004 0.90
25 Low sensitivity of peripheral blood smear for diagnosis of subclinical visceral leishmaniasis in human immunodeficiency virus type 1-infected patients. J Clin Microbiol 1998 0.89
26 Changes in the rate of genotypic resistance to antiretroviral drugs in Spain. AIDS 2001 0.89
27 Usefulness of route of transmission, absolute CD8+ T-cell counts, and levels of serum tumor necrosis factor alpha as predictors of survival of HIV-1-infected patients with very low CD4 + T-cell counts. Eur J Clin Microbiol Infect Dis 2001 0.89
28 Is hepatitis G virus transmitted sexually? JAMA 1997 0.89
29 Influence of hepatitis C virus infection on the mortality of antiretroviral-treated patients with HIV disease. Eur J Clin Microbiol Infect Dis 1998 0.89
30 Zinc alpha-2 glycoprotein is implicated in dyslipidaemia in HIV-1-infected patients treated with antiretroviral drugs. HIV Med 2012 0.89
31 Emergence and clinical relevance of mutations associated with zidovudine resistance in asymptomatic HIV-1 infected patients. Eur J Clin Microbiol Infect Dis 1995 0.88
32 Primary HIV-1 drug resistance in Spain before and after the introduction of protease inhibitors. J Med Virol 2001 0.87
33 Prevention of post-transfusion non-A, non-B hepatitis by non-specific immunoglobulin in heart surgery patients. Lancet 1988 0.87
34 Specific patterns of CD4-associated immunosenescence in vertically HIV-infected subjects. Clin Microbiol Infect 2012 0.87
35 Changes in thymus volume in adult HIV-infected patients under HAART: correlation with the T-cell repopulation. Clin Exp Immunol 2002 0.87
36 Increase in the frequency of mutation at codon 215 associated with zidovudine resistance in HIV-1-infected antiviral-naive patients from 1989 to 1996. AIDS 1997 0.86
37 Reduction of immune system activation in HIV-1-infected patients undergoing highly active antiretroviral therapy. Eur J Clin Microbiol Infect Dis 1999 0.85
38 HCV RNA in peripheral blood cell subsets in HCV-HIV coinfected patients at the end of PegIFN/RBV treatment is associated with virologic relapse. J Viral Hepat 2008 0.85
39 Correlation of the virological response to short-term maraviroc monotherapy with standard and deep-sequencing-based genotypic tropism prediction methods. Antimicrob Agents Chemother 2011 0.85
40 Influence of highly active antiretroviral therapy on the outcome of subclinical visceral leishmaniasis in human immunodeficiency virus-infected patients. Clin Infect Dis 2001 0.85
41 Hepatitis C virus infection among sexually promiscuous groups and the heterosexual partners of hepatitis C virus infected index cases. Eur J Clin Microbiol Infect Dis 1993 0.84
42 Significance of indeterminate reactivity to human T-cell lymphotropic virus in western blot analysis of individuals at risk. Eur J Clin Microbiol Infect Dis 1997 0.83
43 Tumor necrosis factor beta and soluble APO-1/Fas independently predict progression to AIDS in HIV-seropositive patients. AIDS Res Hum Retroviruses 1998 0.82
44 Efficiency of drug resistance genotypic tests in specimens with low HIV viral load. Antivir Ther 1999 0.82
45 Patient HIV-1 strains carrying the multiple nucleoside resistance mutations are cross-resistant to abacavir. AIDS 2000 0.81
46 Rhodococcus or mycobacterium? An example of misdiagnosis in HIV infection. AIDS 1997 0.81
47 HIV-1 plasma viremia not increased in patients receiving highly active antiretroviral therapy after influenza vaccination. Eur J Clin Microbiol Infect Dis 2001 0.81
48 Prevalence of infection by human T-cell leukemia virus types I and II in southern Spain. Eur J Clin Microbiol Infect Dis 1995 0.80
49 Dietary α-Linolenic Acid, Marine ω-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta MEDiterránea (PREDIMED) Study. J Am Heart Assoc 2016 0.80
50 [P. falciparum and P. malariae malaria complicated by pulmonary edema with disseminated intravascular coagulation]. Presse Med 1983 0.80
51 Combination treatment with clomipramine and fluvoxamine: drug monitoring, safety, and tolerability data. J Clin Psychiatry 1996 0.80
52 Melatonin biosynthesis in the thymus of humans and rats. Cell Mol Life Sci 2007 0.79
53 Spectrofluorimetric analysis of CCR5-delta 32 allele using real-time polymerase chain reaction: prevalence in southern Spanish HIV(+) patients and noninfected population. AIDS Res Hum Retroviruses 2001 0.79
54 Analysis of quasispecies in the viral 5' untranslated region of hepatitis C virus to evaluate ribavirin mutagenic effect in patients receiving ribavirin and interferon-alfa. Eur J Clin Microbiol Infect Dis 2004 0.79
55 [Impact of medical approach on the presentation form of AIDS defined by clinical episodes]. Med Clin (Barc) 1998 0.79
56 Short-term outcome of infliximab and other medications on patients with inflammatory bowel disease undergoing ileostomy reversal. Colorectal Dis 2011 0.78
57 Dynamics of serum cytokines in patients with visceral leishmaniasis and HIV-1 co-infection. Clin Exp Immunol 1998 0.78
58 Structural normalization of the lymphoid tissue in asymptomatic HIV-infected patients after 48 weeks of potent antiretroviral therapy. AIDS 2001 0.78
59 Minimal liver injury in chronic hepatitis C virus infection is associated with low levels of soluble TNF-alpha/Fas receptors and acquisition in childhood. Liver 2001 0.78
60 Regression of invasive AIDS-related Kaposi's sarcoma following antiretroviral therapy. Clin Infect Dis 1998 0.77
61 CD4+ T-lymphocytopenia in the elderly. Eur J Clin Microbiol Infect Dis 1995 0.77
62 [Prevalence of anti-LAV/HTLV-III in prostitutes in Seville]. Med Clin (Barc) 1986 0.77
63 NK-associated regulatory receptors in a structured HAART interruption of HIV-1-positive individuals. AIDS Res Hum Retroviruses 2008 0.77
64 Genetic drift or natural selection? Hybridization and asymmetric mitochondrial introgression in two Caribbean lizards (Anolis pulchellus and Anolis krugi). J Evol Biol 2013 0.76
65 Hepatitis E virus and HIV infection in homosexual men. Lancet 1995 0.76
66 Relationship between systemic drug absorption and gastrointestinal transit after the simultaneous oral administration of carbamazepine as a controlled-release system and as a suspension of 15N-labelled drug to healthy volunteers. Br J Clin Pharmacol 1991 0.76
67 Is it age or HIV that drives the regulatory T-cells expansion that occurs in older HIV-infected persons? Clin Immunol 2010 0.76
68 Evidence for a role of T-helper type 2 cytokines in the acquisition of human immunodeficiency virus syncytium-inducing phenotype. Eur J Clin Invest 1998 0.76
69 [Absence of antibodies against the acquired immune deficiency syndrome virus in hospital personnel in contact with risk groups]. Med Clin (Barc) 1986 0.76
70 Acquisition of syncytium-inducing HIV-1 strains during therapy with zidovudine alone or combined with alpha interferon or didanosine. Eur J Clin Microbiol Infect Dis 1996 0.75
71 Does early zidovudine treatment prevent the emergency of syncytium-inducing human immunodeficiency virus? J Infect Dis 1994 0.75
72 HIV-1-Ag as the one marker in the early stage of HIV-1 infection. Vox Sang 1991 0.75
73 [Infection caused by human immunodeficiency virus type 1 in individuals with negative serology. Is it really frequent?]. Med Clin (Barc) 1992 0.75
74 HIV-1 progression in hepatitis-C-infected drug users. Lancet 2001 0.75
75 Circulating interleukin 2 in rapidly progressive glomerulonephritis. Nephrol Dial Transplant 1990 0.75
76 [Liver cirrhosis and the renin-angiotensin-aldosterone system]. Rev Esp Enferm Apar Dig 1986 0.75
77 [Significance of lymph node histology in patients with human immunodeficiency virus infection]. Rev Clin Esp 1988 0.75
78 [Effect of treatment with nucleoside analogues in subjects with primary genotypic resistance to zidovudine]. Med Clin (Barc) 1996 0.75
79 [Treatment against human immunodeficiency virus in terms of the viral load: yes or no?]. Med Clin (Barc) 1996 0.75
80 [Calcification and contamination as complications in the use of double-J catheters: incidence and correlation]. Actas Urol Esp 1990 0.75
81 [Hepatitis caused by diphenylhydantoin]. Med Clin (Barc) 1984 0.75
82 Long-term benefits of nevirapine-containing regimens: multicenter study with 506 patients, followed-up a median of 9 years. Curr HIV Res 2012 0.75
83 High rate of nonspecific anti-hepatitis C reactivity amongst homosexual men in comparison with that found in other sexually active groups and blood donors. Viral Hepatitis and AIDS Study Group. J Intern Med 1994 0.75
84 [Impact of acquired immunodeficiency syndrome on sex habits of a cohort of homosexuals]. Med Clin (Barc) 1988 0.75
85 [Multicenter study of the prevalence of type 2 human immunodeficiency virus infection in Spain (1990)]. Med Clin (Barc) 1992 0.75
86 [Poikilodermis]. Ann Dermatol Venereol 2001 0.75
87 [Comparison of radioimmunoassay with enzyme immunoassay in the detection of serum antibodies against the human immunodeficiency virus]. Med Clin (Barc) 1987 0.75
88 [Lymphocyte subpopulations in hemophilia A and B]. Med Clin (Barc) 1984 0.75
89 [Penetration of the infection caused by type 2 human immunodeficiency virus in Andalusian individuals at risk]. Med Clin (Barc) 1989 0.75
90 Quantitative determination of a new anticonvulsant (CGS 18416A) in human plasma using capillary gas chromatography/mass spectrometry. Biomed Chromatogr 1993 0.75
91 [GESIDA Consensus document on the use of resistance studies in clinical practice]. Enferm Infecc Microbiol Clin 2001 0.75
92 Presence of genotypic resistance in nucleoside analogue-treated HIV-1-infected patients with undetectable viral load. Antivir Ther 1999 0.75
93 Immunological and virological effects of highly active antiretroviral therapy in two HIV-1 infected children. Acta Paediatr 2000 0.75
94 Failure to detect silent HIV infection by polymerase chain reaction in subjects at risk for heterosexually transmitted HIV type 1 infection. Eur J Clin Microbiol Infect Dis 1993 0.75
95 Antibodies to human T-cell leukemia virus type III in hemophiliacs from Spain. Blood 1985 0.75
96 Hepatitis C virus infection in sexually promiscuous groups. Eur J Clin Microbiol Infect Dis 1990 0.75
97 Predictive factors influencing peak viral load drop in response to nucleoside reverse transcriptase inhibitors in antiretroviral-naive HIV-1-infected patients. J Acquir Immune Defic Syndr Hum Retrovirol 1998 0.75
98 [First case of acquired immune deficiency syndrome in a drug addict from Seville]. Med Clin (Barc) 1986 0.75
99 [HIV-1 and HIV-2 coinfection or cross reaction?]. Med Clin (Barc) 1990 0.75
100 [Chronic hepatitis C in patients coinfected by human immunodeficiency virus]. Gastroenterol Hepatol 2002 0.75
101 [Cost-benefit analysis of a program for vaccination against hepatitis B in health personnel of a hospital]. Med Clin (Barc) 1984 0.75
102 [Strategies for the prevention of human immunodeficiency virus infection]. Rev Clin Esp 1995 0.75
103 [The prevention of AIDS]. An Med Interna 1992 0.75
104 [Retrovirus, drugs, and sex: a reflection beyond medicine]. Med Clin (Barc) 1995 0.75
105 [An evaluation of the efficacy of different commercial kits in the serological diagnosis of the early phase of human immunodeficiency virus infection]. Med Clin (Barc) 1990 0.75
106 [Enzyme immunoassay using recombinant env peptides of human immunodeficiency virus type 1 (HIV-1) as a confirmatory technic for anti-HIV-1]. Med Clin (Barc) 1989 0.75
107 Avoiding indeterminate results in HIV-1 western blot using synthetic peptide assays. HIV-2 Spanish Study Group. Vox Sang 1993 0.75
108 [Zidovudine and human immunodeficiency virus infection: when and how to initiate treatment]. Med Clin (Barc) 1991 0.75
109 [Opportunistic infections and Kaposi's sarcoma in hemophiliacs. Analysis of a series of patients controlled in a hospital and evaluation of the medical behavior]. Rev Clin Esp 1987 0.75
110 [Prevention of the maternofilial transmission of the human immunodeficiency virus]. Med Clin (Barc) 1987 0.75
111 [Should esophageal candidiasis be excluded from diagnostic criteria for acquired immunodeficiency syndrome?]. Med Clin (Barc) 1986 0.75
112 Pain as a mutual experience for patients, nurses and families: a perspective from Valencia, Spain. J Cult Divers 2000 0.75
113 [Human immunodeficiency virus type 2 infection: is it really present in our area?]. Med Clin (Barc) 1990 0.75
114 [Delta infection in homosexual males]. Med Clin (Barc) 1985 0.75
115 [Evidence of exposure to the virus of acquired immune deficiency syndrome in risk groups from the Seville area. Preliminary evaluation]. Med Clin (Barc) 1986 0.75
116 Cytokine network and HIV syncytium-inducing phenotype shift. AIDS 1996 0.75
117 Recombinant EIA for anti-HIV testing is more specific than conventional EIA. Vox Sang 1988 0.75
118 A pilot case-control study of zidovudine compared with zidovudine plus didanosine in patients with advanced HIV-1 disease and no previous experience with antiretrovirals. Antivir Ther 1996 0.75
119 Fourth case of AIDS in haemophilic children in Seville. Lancet 1984 0.75
120 Absence of HTLV-I and HTLV-II infection in prostitutes in the area of Seville, Spain. Eur J Clin Microbiol Infect Dis 1991 0.75
121 Effect of the substitution of one nucleoside analogue by one non-nucleoside reverse transcriptase inhibitor over mitochondrial DNA levels. Infection 2008 0.75
122 [Serum expression of human immunodeficiency virus antigen(s) in persons at risk. Evidence of disappearance of HIV-Ag during the developmental course of patients with acquired immunodeficiency syndrome]. Med Clin (Barc) 1987 0.75
123 Evolution of genotypic resistance to nucleoside analogues in patients receiving protease inhibitor-containing regimens. Antivir Ther 1999 0.75
124 A retrospective study of allergic diseases in children with food hypersensitivity. Allergol Immunopathol (Madr) 2009 0.75
125 Viraemia and p24 antigenaemia are independent risk factors for the emergency of a zidovudine-resistant genotype in nucleoside analogue-treated HIV-1 infection. Antivir Ther 1997 0.75
126 Short-term evolution of HIV-1 viraemia and CD4+ cell counts in patients who have a primary mutation to zidovudine. AIDS 1998 0.75
127 Provirus load changes in untreated and zidovudine-treated human immunodeficiency virus type 1-infected patients. J Infect Dis 1994 0.75
128 [Prevalence of human immunodeficiency virus antibodies in inmates and officials of penitentiaries]. Rev Clin Esp 1987 0.75
129 Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of carbamazepine and its main metabolites. J Chromatogr B Biomed Sci Appl 1998 0.75
130 Influence of hepatitis C and hepatitis G virus co-infection on viral and cellular dynamics in patients infected with human immunodeficiency virus following interruption of highly active anti-retroviral therapy. Clin Microbiol Infect 2006 0.75
131 [Myxoma of the right atrium. Unusual hemodynamic data and ultrastructural study]. Med Clin (Barc) 1983 0.75
132 [Infection by hepatitis B virus in prostitutes: a public health problem]. Med Clin (Barc) 1986 0.75
133 [A multicenter study of infection with human immunodeficiency virus type-2 (HIV-2) in Spain (1991). The Spanish Group for the Study of HIV-2]. Med Clin (Barc) 1993 0.75
134 [Comparison of a competitive enzyme immunoassay with Western blot in the detection of anti-HIV-1]. Enferm Infecc Microbiol Clin 1990 0.75
135 [Acquired immunodeficiency syndrome (AIDS) in hemophiliacs. Clinical course and post-mortem examination of the first cases described in Spain]. Med Clin (Barc) 1984 0.75
136 Can the determination of HIV-1 Ag in serum be useful in identifying hemophiliac patients who end up developing AIDS? Vox Sang 1989 0.75
137 [Ganglioneuroblastoma in the adult]. Med Clin (Barc) 1983 0.75
138 3D.07: CORRELATION BETWEEN THE ARTERIAL PRESSURE VARIABILITY ESTIMATED AT CLINICS, MAPA AND AMPA. J Hypertens 2015 0.75
139 Rotative agitation RIA. A high sensitivity technique for hepatitis B surface antigen (HBsAg) determinations. J Hepatol 1986 0.75
140 [Intrafamilial horizontal transmission of the human immunodeficiency virus in an area of low incidence]. Med Clin (Barc) 1988 0.75
141 Variational analysis of the transdermal delivery rate from two prototypical ethanol-water nitroglycerin TTS devices and Transderm-Nitro 10 in the normal population. J Pharmacokinet Biopharm 1992 0.75
142 [Acquired immune deficiency syndrome in Spain. Is the alarm justified?]. Med Clin (Barc) 1985 0.75
143 [Acquired cellular immunodeficiency syndrome: 3 observations in hemophiliacs]. Med Clin (Barc) 1983 0.75
144 Low levels of HIV-1 plasma viral load in patients infected with HIV-1 subtype b and advanced immunosuppression. J Infect 2001 0.75
145 Insufficiencies of the new WHO western blot criteria in the diagnosis of HIV-1 and HIV-2 infections. Vox Sang 1992 0.75
146 [Penetration of anti-LVA/HTLV-III in type A and B hemophiliacs. Clinical and immunologic follow-up]. Med Clin (Barc) 1986 0.75
147 AIDS in haemophiliacs in Spain. Lancet 1985 0.75
148 [Infection by human immunodeficiency virus in childhood: the hidden face of parenteral drug addiction]. Med Clin (Barc) 1987 0.75
149 [Serological markers of infection caused by human immunodeficiency virus]. Med Clin (Barc) 1988 0.75
150 Antibodies to the AIDS-associated retrovirus in hemophiliacs and other individuals from southern Spain: lack of correlation with lymphocytes sub-populations. AIDS Res 1986 0.75
151 [Intrafamilial transmission of the virus of acquired immunodeficiency syndrome]. Med Clin (Barc) 1986 0.75
152 [Hepatitis B in hospital personnel]. Med Clin (Barc) 1987 0.75
153 [The seroepidemiology of infection with the human immunodeficiency virus type 2 (HIV-2) in Spain (1990). The Spanish Group for the Study and Follow-up of HIV-2 Infection]. Med Clin (Barc) 1992 0.75
154 Population pharmacodynamic modeling of drug-induced anemia. J Pharm Sci 1993 0.75
155 [Serum and immunological markers of progression to acquired immunodeficiency syndrome in hemophiliacs]. Med Clin (Barc) 1989 0.75
156 [Prevalence of serum markers of hepatitis A and B viruses in Andalusian homosexual men]. Med Clin (Barc) 1985 0.75
157 [Hemoglobin variants and hematologic and serologic parameters of the population of El Limón (Aragua State, Venezuela)]. Invest Clin 1990 0.75
158 [Auto-exclusion of blood donors in relation to human immunodeficiency virus infection: a problem not yet resolved]. Med Clin (Barc) 1987 0.75
159 [Viral hepatitis in hemophiliac patients treated with commercial concentrates of factors VIII and IX]. Med Clin (Barc) 1985 0.75