Published in Thromb Haemost on December 01, 2008
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LOX-1, OxLDL, and atherosclerosis. Mediators Inflamm (2013) 1.35
Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms. PLoS One (2011) 1.21
Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation. J Biol Chem (2013) 1.07
Inhibition of NF-κB prevents high glucose-induced proliferation and plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Exp Mol Med (2011) 0.93
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Circulating levels of inflammatory markers in intrauterine growth restriction. Mediators Inflamm (2010) 0.86
Plasminogen activator inhibitor-2 polymorphism associates with recurrent coronary event risk in patients with high HDL and C-reactive protein levels. PLoS One (2013) 0.81
Chemical Antagonists of Plasminogen Activator Inhibitor-1: Mechanisms of Action and Therapeutic Potential in Vascular Disease. J Mol Genet Med (2014) 0.80
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A new method for in vivo visualization of vessel remodeling using a near-infrared dye. Microcirculation (2011) 0.79
Evaluation of various endothelial biomarkers in ankylosing spondylitis. Clin Rheumatol (2011) 0.78
A translational preclinical model of interstitial pulmonary fibrosis and pulmonary hypertension: mechanistic pathways driving disease pathophysiology. Physiol Rep (2014) 0.77
Coagulation and Fibrinolytic System Protein Profiles in Women with Normal Pregnancies and Pregnancies Complicated by Hypertension. Pregnancy Hypertens (2012) 0.76
A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage. Cell Signal (2015) 0.76
Enlarged pulmonary artery is predicted by vascular injury biomarkers and is associated with WTC-Lung Injury in exposed fire fighters: a case-control study. BMJ Open (2014) 0.76
Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. Int J Mol Sci (2016) 0.75
Small Molecule PAI-1 Functional Inhibitor Attenuates Vascular Smooth Muscle Cell Migration and Survival: Implications for the Therapy of Vascular Disease. New Horiz Transl Med (2014) 0.75
Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop. Protein Sci (2015) 0.75
Targeted Inhibition of PAI-1 Activity Impairs Epithelial Migration and Wound Closure Following Cutaneous Injury. Adv Wound Care (New Rochelle) (2015) 0.75
Fluid Shear Stress and Fibroblast Growth Factor-2 Increase Endothelial Cell-Associated Vitronectin. Appl Bionics Biomech (2017) 0.75
PAI1: a novel PP1-interacting protein that mediates human plasma's anti-apoptotic effect in endothelial cells. J Cell Mol Med (2017) 0.75
Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site. Arterioscler Thromb Vasc Biol (2007) 3.02
Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells. Mol Biol Cell (2007) 2.47
NOX2 and NOX4 mediate proliferative response in endothelial cells. Antioxid Redox Signal (2006) 1.83
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner. Mol Cell Biol (2007) 1.54
NADPH oxidase mediates tissue factor-dependent surface procoagulant activity by thrombin in human vascular smooth muscle cells. Circulation (2002) 1.52
NOX5 variants are functionally active in endothelial cells. Free Radic Biol Med (2006) 1.50
The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1. Mol Biol Cell (2010) 1.49
Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells. Arterioscler Thromb Vasc Biol (2004) 1.39
Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression. Semin Cell Dev Biol (2005) 1.29
The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison. Biochem J (2008) 1.28
Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells. Biol Chem (2004) 1.23
Receptor activation of NADPH oxidases. Antioxid Redox Signal (2010) 1.18
The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression. Free Radic Biol Med (2002) 1.14
Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation. Circ Res (2004) 1.14
GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α. Blood (2011) 1.10
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med (Berl) (2006) 1.10
The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin. Circ Res (2006) 1.08
Phosphodiesterase 2 mediates redox-sensitive endothelial cell proliferation and angiogenesis by thrombin via Rac1 and NADPH oxidase 2. Circ Res (2009) 1.06
Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies. J Enzyme Inhib Med Chem (2009) 1.04
Rac-1 promotes pulmonary artery smooth muscle cell proliferation by upregulation of plasminogen activator inhibitor-1: role of NFkappaB-dependent hypoxia-inducible factor-1alpha transcription. Thromb Haemost (2008) 1.03
Targeting SGK1 in diabetes. Expert Opin Ther Targets (2009) 1.02
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors. Mol Cancer Res (2011) 1.02
The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells. Free Radic Biol Med (2005) 1.00
The hypoxia-inducible factor-2alpha is stabilized by oxidative stress involving NOX4. Antioxid Redox Signal (2010) 0.99
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. J Enzyme Inhib Med Chem (2014) 0.96
Rac regulates thrombin-induced tissue factor expression in pulmonary artery smooth muscle cells involving the nuclear factor-kappaB pathway. Antioxid Redox Signal (2004) 0.94
Reciprocal regulation of Rac1 and PAK-1 by HIF-1alpha: a positive-feedback loop promoting pulmonary vascular remodeling. Antioxid Redox Signal (2010) 0.92
Functional analyses reveal the greater potency of preadipocytes compared with adipocytes as endothelial cell activator under normoxia, hypoxia, and TNFalpha exposure. Am J Physiol Endocrinol Metab (2009) 0.91
Control of adenosine transport by hypoxia. Circ Res (2005) 0.90
Regulation of the hypoxia-dependent plasminogen activator inhibitor 1 expression by MAP kinases. Thromb Haemost (2003) 0.89
Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease. Physiol Genomics (2010) 0.87
NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II. Mol Biol Cell (2011) 0.86
Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver. Arch Biochem Biophys (2007) 0.86
Insights into the redox control of blood coagulation: role of vascular NADPH oxidase-derived reactive oxygen species in the thrombogenic cycle. Antioxid Redox Signal (2004) 0.86
The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II. J Cell Sci (2012) 0.86
The hypoxia-inducible factor HIF-1 promotes intramyocardial expression of VEGF in infants with congenital cardiac defects. Basic Res Cardiol (2007) 0.85
Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus. Implications for local drug delivery. Thromb Haemost (2007) 0.83
The role of nitric oxide radicals in removal of hyper-radiosensitivity by priming irradiation. J Radiat Res (2013) 0.83
Early determinants of pulmonary vascular remodeling in animal models of complex congenital heart disease. Circulation (2011) 0.82
Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α. Clin Exp Metastasis (2010) 0.81
The role of hypoxia inducible factor-1 in cell metabolism--a possible target in cancer therapy. Expert Opin Ther Targets (2006) 0.81
Urotensin-II in the lung: a matter for vascular remodelling and pulmonary hypertension? Thromb Haemost (2007) 0.81
Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1alpha with a hypoxia-tolerant tumor cell line. J Biol Chem (2010) 0.80
Heterocyclic indazole derivatives as SGK1 inhibitors, WO2008138448. Expert Opin Ther Pat (2010) 0.78
Redox control of tissue factor expression in smooth muscle cells and other vascular cells. Methods Enzymol (2002) 0.77
Vascular remodelling processes: cells, signals and their integration. Thromb Haemost (2007) 0.76
Redox control of blood coagulation. Antioxid Redox Signal (2004) 0.75
The β3-integrin binding protein β3-endonexin is a novel negative regulator of hypoxia-inducible factor-1. Antioxid Redox Signal (2014) 0.75
Inhibition of endothelial nitric oxyde synthase increases capillary formation via Rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1. Thromb Haemost (2012) 0.75
Regulation of the hypoxia-inducible transcription factor HIF-1 by reactive oxygen species in smooth muscle cells. Adv Exp Med Biol (2003) 0.75
Accounting for biological variation in differential display two-dimensional electrophoresis experiments. J Proteomics (2012) 0.75