James B Aggen

Author PubWeight™ 8.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. Antimicrob Agents Chemother 2009 1.38
2 A central strategy for converting natural products into fluorescent probes. Chembiochem 2006 1.21
3 In vivo efficacy of the novel aminoglycoside ACHN-490 in murine infection models. Antimicrob Agents Chemother 2011 1.11
4 Exploring the positional attachment of glycopeptide/beta-lactam heterodimers. J Antibiot (Tokyo) 2008 1.01
5 A multivalent approach to drug discovery for novel antibiotics. J Antibiot (Tokyo) 2008 0.84
6 Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors. Bioorg Med Chem Lett 2003 0.82
7 Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs. ACS Chem Biol 2014 0.81
8 Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A. Bioorg Med Chem Lett 2003 0.78
9 1-(4-Phenylpiperazin-1-yl)-2-(1H-pyrazol-1-yl)ethanones as novel CCR1 antagonists. Bioorg Med Chem Lett 2013 0.76