| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Antibacterial activity of some Peruvian medicinal plants from the Callejon de Huaylas.
|
J Ethnopharmacol
|
2002
|
1.35
|
|
2
|
Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon).
|
J Agric Food Chem
|
2002
|
1.26
|
|
3
|
Recent advances in the isolation and reactivity of organogold complexes.
|
Chem Soc Rev
|
2012
|
1.07
|
|
4
|
Synthesis, cytotoxicity, and anti-Trypanosoma cruzi activity of new chalcones.
|
J Med Chem
|
2008
|
1.06
|
|
5
|
Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae).
|
Phytochemistry
|
2005
|
1.04
|
|
6
|
Synthesis and structural characterization of stable organogold(I) compounds. Evidence for the mechanism of gold-catalyzed cyclizations.
|
J Am Chem Soc
|
2008
|
1.03
|
|
7
|
Ligand effects and ligand design in homogeneous gold(I) catalysis.
|
J Am Chem Soc
|
2012
|
1.02
|
|
8
|
Thermodynamically favored aldol reaction of propargyl or allenyl esters: regioselective synthesis of carbinol allenoates.
|
Angew Chem Int Ed Engl
|
2008
|
0.95
|
|
9
|
Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes.
|
J Am Chem Soc
|
2010
|
0.94
|
|
10
|
Designer HF-based fluorination reagent: highly regioselective synthesis of fluoroalkenes and gem-difluoromethylene compounds from alkynes.
|
J Am Chem Soc
|
2014
|
0.94
|
|
11
|
Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading.
|
Org Biomol Chem
|
2006
|
0.91
|
|
12
|
Concise preparation of 2,2-difluorohomopropargyl carbonyl derivatives. Application to the synthesis of 4,4-difluoroisoquinolinone congeners.
|
J Org Chem
|
2008
|
0.90
|
|
13
|
In vitro and in vivo anti-Leishmania activity of polysubstituted synthetic chalcones.
|
Bioorg Med Chem Lett
|
2009
|
0.90
|
|
14
|
Fluorine-enabled cationic gold catalysis: functionalized hydration of alkynes.
|
Angew Chem Int Ed Engl
|
2010
|
0.89
|
|
15
|
Regiospecific synthesis of bicyclo- and heterobicyclo-gem-difluorocyclobutenes using functionalized fluoroallenes and a novel Mo-catalyzed intramolecular [2 + 2] cycloaddition reaction.
|
J Am Chem Soc
|
2002
|
0.89
|
|
16
|
Use of a modified microplate bioassay method to investigate antibacterial activity in the Peruvian medicinal plant Peperomia galioides.
|
J Ethnopharmacol
|
2004
|
0.88
|
|
17
|
Cationic gold catalyst poisoning and reactivation.
|
Org Lett
|
2014
|
0.87
|
|
18
|
In vivo wound-healing activity of oleanolic acid derived from the acid hydrolysis of Anredera diffusa.
|
J Nat Prod
|
2006
|
0.85
|
|
19
|
Antihyperlipidemic compounds from the fruit of Piper longum L.
|
Phytother Res
|
2009
|
0.85
|
|
20
|
Identification of triterpene hydroxycinnamates with in vitro antitumor activity from whole cranberry fruit (Vaccinium macrocarpon).
|
J Agric Food Chem
|
2003
|
0.85
|
|
21
|
Synthesis of functionalized alpha,alpha-disubstituted beta-alkynyl esters from allenoates through an alkynylenolate intermediate.
|
Org Lett
|
2008
|
0.85
|
|
22
|
Recent synthetic additions to the visible light photoredox catalysis toolbox.
|
Org Biomol Chem
|
2015
|
0.84
|
|
23
|
Intramolecular hydroamination of difluoropropargyl amides: regioselective synthesis of fluorinated beta- and gamma-lactams.
|
Org Lett
|
2007
|
0.84
|
|
24
|
Cytotoxic and anti-infective sesquiterpenes present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae).
|
Planta Med
|
2009
|
0.84
|
|
25
|
A highly efficient and broadly applicable cationic gold catalyst.
|
Angew Chem Int Ed Engl
|
2014
|
0.83
|
|
26
|
Physangulidines A, B, and C: three new antiproliferative withanolides from Physalis angulata L.
|
Org Lett
|
2012
|
0.83
|
|
27
|
AuX3-mediated selective head-to-head dimerization of difluoropropargyl amides.
|
J Org Chem
|
2009
|
0.83
|
|
28
|
Reactions of cationic gold(I) with allenoates: synthesis of stable organogold(I) complexes and mechanistic investigations on gold-catalyzed cyclizations.
|
Chem Asian J
|
2009
|
0.83
|
|
29
|
Alkyne/alkene/allene-induced disproportionation of cationic gold(I) catalyst.
|
Chemistry
|
2014
|
0.83
|
|
30
|
Synthesis of α-CN and α-CF3 N-heterocycles through tandem nucleophilic additions.
|
Org Lett
|
2011
|
0.82
|
|
31
|
Gold-catalyzed addition of N-hydroxy heterocycles to alkynes and subsequent 3,3-sigmatropic rearrangement.
|
Org Lett
|
2013
|
0.82
|
|
32
|
Synthesis of 2,4,5-trisubstituted 3-fluorofurans via sequential iodocyclization and cross-coupling of gem-difluorohomopropargyl alcohols.
|
J Org Chem
|
2008
|
0.82
|
|
33
|
A multipronged approach to the study of peruvian ethnomedicinal plants: a legacy of the ICBG-Peru Project.
|
J Nat Prod
|
2009
|
0.81
|
|
34
|
Aegicerin, the first oleanane triterpene with wide-ranging antimycobacterial activity, isolated from Clavija procera.
|
J Nat Prod
|
2006
|
0.81
|
|
35
|
Difluoroallenyl bromide as a wide-ranging difluoromethylene cation equivalent: SN2 substitution of difluoropropargyl bromide through sequential SE2' and SN2' reactions.
|
Angew Chem Int Ed Engl
|
2005
|
0.81
|
|
36
|
Isolation of cytotoxic metabolites from targeted peruvian amazonian medicinal plants.
|
J Nat Prod
|
2007
|
0.80
|
|
37
|
Selective synthesis of fluorinated furan derivatives via AgNO3-catalyzed activation of an electronically deficient triple bond.
|
J Org Chem
|
2007
|
0.80
|
|
38
|
Michael addition of allenoates to electron-deficient olefins: facile synthesis of 2-alkynyl-substituted glutaric acid derivatives.
|
Org Lett
|
2008
|
0.78
|
|
39
|
Crystallographic characterization of difluoropropargyl indium bromide, a reactive fluoroorganometallic reagent.
|
Angew Chem Int Ed Engl
|
2006
|
0.78
|
|
40
|
Enhanced reactivity in homogeneous gold catalysis through hydrogen bonding.
|
Org Lett
|
2014
|
0.78
|
|
41
|
Highly efficient and tunable synthesis of dioxabicyclo[4.2.1] ketals and tetrahydropyrans via gold-catalyzed cycloisomerization of 2-alkynyl-1,5-diols.
|
Org Lett
|
2009
|
0.78
|
|
42
|
Efficient generation and increased reactivity in cationic gold via Brønsted acid or Lewis acid assisted activation of an imidogold precatalyst.
|
Org Lett
|
2014
|
0.78
|
|
43
|
Supported gold nanoparticle-catalyzed hydration of alkynes under basic conditions.
|
Org Lett
|
2014
|
0.77
|
|
44
|
Efficient synthesis of gamma-keto esters through neighboring carbonyl group-assisted regioselective hydration of 3-alkynoates.
|
J Org Chem
|
2009
|
0.77
|
|
45
|
The [4+2], not [2+2], mechanism occurs in the gold-catalyzed intramolecular oxygen transfer reaction of 2-alkynyl-1,5-diketones.
|
Angew Chem Int Ed Engl
|
2010
|
0.77
|
|
46
|
Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines.
|
Bioorg Med Chem
|
2010
|
0.77
|
|
47
|
Cytotoxic and anti-infective phenolic compounds isolated from Mikania decora and Cremastosperma microcarpum.
|
Planta Med
|
2011
|
0.76
|
|
48
|
A new convenient synthesis of propargylic fluorohydrins and 2,5-disubstituted furans from fluoropropargyl chloride.
|
J Org Chem
|
2006
|
0.75
|
|
49
|
Synthesis of Pyrrolidines and Pyrroles via Tandem Amination/Cyanation/Alkylation and Amination/Oxidation Sequences.
|
European J Org Chem
|
2014
|
0.75
|
|
50
|
Construction of cyclic enones via gold-catalyzed oxygen transfer reactions.
|
Beilstein J Org Chem
|
2011
|
0.75
|
|
51
|
Synthesis of fluorinated δ-lactams via cycloisomerization of gem-difluoropropargyl amides.
|
Beilstein J Org Chem
|
2010
|
0.75
|
|
52
|
Gold-catalyzed cascade annulations of 2-(ynol)aryl aldehydes: facile synthesis of benzochromanes and benzobicyclo[n.3.1]acetals.
|
Org Lett
|
2010
|
0.75
|
|
53
|
Gold-catalyzed, intramolecular, oxygen-transfer reactions of 2-alkynyl-1,5-diketones or 2-alkynyl-5-ketoesters: scope, expansion, and mechanistic investigations on a new [4+2] cycloaddition.
|
Chemistry
|
2011
|
0.75
|
|
54
|
Anti-infective and cytotoxic compounds present in Blepharodon nitidum.
|
Planta Med
|
2008
|
0.75
|
|
55
|
Potassium tris(triflyl)methide (KCTf3): a broadly applicable promoter for cationic metal catalysis.
|
Chem Commun (Camb)
|
2015
|
0.75
|
|
56
|
Supported gold nanoparticles catalyzed cis-selective semihydrogenation of alkynes using ammonium formate as the reductant.
|
Chem Commun (Camb)
|
2016
|
0.75
|
|
57
|
Efficient hydration of alkynes through acid-assisted Brønsted acid catalysis.
|
Chem Commun (Camb)
|
2014
|
0.75
|
|
58
|
Widely Applicable Hydrofluorination of Alkenes via Bifunctional Activation of Hydrogen Fluoride.
|
J Am Chem Soc
|
2017
|
0.75
|
|
59
|
Isolation of the active compound in Mauria heterophylla, a Peruvian plant with antibacterial activity.
|
Phytother Res
|
2006
|
0.75
|
|
60
|
Ligand design in gold catalysis and chemistry of gold-oxonium intermediates.
|
Top Curr Chem
|
2015
|
0.75
|
|
61
|
Intrapilosins I-VII, pentasaccharides from the seeds of Ipomoea intrapilosa.
|
J Nat Prod
|
2007
|
0.75
|
|
62
|
Functionalization of monofluoroallene and the synthesis of aryl-substituted conjugated fluorodienes.
|
Org Lett
|
2002
|
0.75
|
|
63
|
On the nature of organoindium intermediates: the formation of readily isolable difluoropropargylindium reagents and their regioselectivity towards electrophilic substitutions.
|
Chemistry
|
2008
|
0.75
|
|
64
|
Physangulidine A, a withanolide from Physalis angulata, perturbs the cell cycle and induces cell death by apoptosis in prostate cancer cells.
|
J Nat Prod
|
2012
|
0.75
|
|
65
|
TBAF-mediated aldol reaction of beta-allenoates: regio- and stereoselective synthesis of (2E,4E)-4-carbinol alkadienoates.
|
J Org Chem
|
2009
|
0.75
|
|
66
|
Rapid chemical reaction workup based on a rigid solvent extraction.
|
Org Lett
|
2014
|
0.75
|
|
67
|
Stereoselective synthesis of monofluoroalkyl α,β-unsaturated ketones from allenyl carbinol esters mediated by gold and Selectfluor.
|
J Org Chem
|
2012
|
0.75
|
|
68
|
Lanthanide triflate-catalyzed preparation of beta,beta-difluorohomopropargyl alcohols in aqueous media. Application to the synthesis of 4,4-difluoroisochromans.
|
J Org Chem
|
2006
|
0.75
|
|
69
|
Highly regioselective synthesis of gem-difluoroallenes through magnesium organocuprate SN2' substitution.
|
Org Lett
|
2006
|
0.75
|
|
70
|
Highly regioselective fluorination and iodination of alkynyl enolates.
|
Org Lett
|
2008
|
0.75
|