Published in Pharmacogenet Genomics on March 01, 2009
Are evidence standards different for genomic- vs. clinical-based precision medicine? - A quantitative analysis of individualized warfarin therapy. Clin Pharmacol Ther (2017) 1.39
Genetics informatics trial (GIFT) of warfarin to prevent deep vein thrombosis (DVT): rationale and study design. Pharmacogenomics J (2011) 1.38
Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy. Thromb Haemost (2011) 1.35
The future of warfarin pharmacogenetics in under-represented minority groups. Future Cardiol (2012) 1.25
Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis. PLoS One (2012) 1.24
Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy. J Thromb Haemost (2009) 1.22
The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era. Hum Genet (2012) 1.16
Role of pharmacogenomics in the management of traditional and novel oral anticoagulants. Pharmacotherapy (2011) 1.16
Clinical application of pharmacogenetic-based warfarin-dosing algorithm in patients of Han nationality after rheumatic valve replacement: a randomized and controlled trial. Int J Med Sci (2012) 1.14
VKORC1-1639G>A, CYP2C9, EPHX1691A>G genotype, body weight, and age are important predictors for warfarin maintenance doses in patients with mechanical heart valve prostheses in southwest China. Eur J Clin Pharmacol (2010) 0.98
Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon. Br J Clin Pharmacol (2014) 0.97
The pharmacogenetics of the response to warfarin in Chinese. Br J Clin Pharmacol (2012) 0.95
A systems approach to designing effective clinical trials using simulations. Circulation (2012) 0.89
A pharmacogenetics-based warfarin maintenance dosing algorithm from Northern Chinese patients. PLoS One (2014) 0.87
Role of cytochrome P450 genotype in the steps toward personalized drug therapy. Pharmgenomics Pers Med (2011) 0.83
Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis. Curr Pharmacogenomics Person Med (2011) 0.82
The Creating an Optimal Warfarin Nomogram (CROWN) Study. Thromb Haemost (2011) 0.82
Genotype-guided drug prescribing: a systematic review and meta-analysis of randomized control trials. Br J Clin Pharmacol (2015) 0.82
Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin. Semin Thromb Hemost (2012) 0.81
Pharmacogenetics-Based versus Conventional Dosing of Warfarin: A Meta-Analysis of Randomized Controlled Trials. PLoS One (2015) 0.81
CYP2C9 and VKORC1 polymorphisms influence warfarin dose variability in patients on long-term anticoagulation. Eur J Clin Pharmacol (2012) 0.80
Cardiovascular pharmacogenomics: current status and future directions-report of a national heart, lung, and blood institute working group. J Am Heart Assoc (2012) 0.79
Comparison of Nine Statistical Model Based Warfarin Pharmacogenetic Dosing Algorithms Using the Racially Diverse International Warfarin Pharmacogenetic Consortium Cohort Database. PLoS One (2015) 0.78
Meta-analysis of Randomized Controlled Trials of Genotype-Guided vs Standard Dosing of Warfarin. Chest (2015) 0.78
Limited clinical utility of genotype-guided warfarin initiation dosing algorithms versus standard therapy: a meta-analysis and trial sequential analysis of 11 randomized controlled trials. Pharmacogenomics J (2015) 0.77
VKORC1 and CYP2C9 Genotype Variations in Relation to Warfarin Dosing in Korean Stroke Patients. J Stroke (2013) 0.77
Verification of pharmacogenetics-based warfarin dosing algorithms in Han-Chinese patients undertaking mechanic heart valve replacement. PLoS One (2014) 0.77
Personalized genomes and cardiovascular disease. Cold Spring Harb Perspect Med (2014) 0.77
Cytochrome P450 oxidoreductase genetic polymorphisms A503V and rs2868177 do not significantly affect warfarin stable dosage in Han-Chinese patients with mechanical heart valve replacement. Eur J Clin Pharmacol (2013) 0.77
Genetics of warfarin sensitivity in an emergency department population with thromboembolic. West J Emerg Med (2011) 0.75
Genetic polymorphisms of patients on stable warfarin maintenance therapy in a Ghanaian population. BMC Res Notes (2016) 0.75
Development of a novel individualized warfarin dose algorithm based on a population pharmacokinetic model with improved prediction accuracy for Chinese patients after heart valve replacement. Acta Pharmacol Sin (2017) 0.75
Impact of CYP2C9, VKORC1 and CYP4F2 genetic polymorphisms on maintenance warfarin dosage in Han-Chinese patients: A systematic review and meta-analysis. Meta Gene (2016) 0.75
Personalized healthcare in clotting disorders. Per Med (2010) 0.75
Development and Comparison of Warfarin Dosing Algorithms in Stroke Patients. Yonsei Med J (2016) 0.75
Impact of the CYP4F2 gene polymorphisms on the warfarin maintenance dose: A systematic review and meta-analysis. Biomed Rep (2016) 0.75
Verification of five pharmacogenomics-based warfarin administration models. Indian J Pharmacol (2016) 0.75
Warfarin-induced life-threatening bleeding associated with a CYP3A4 loss-of-function mutation in an acute limb ischemia patient: Case report and review of the literature. Exp Ther Med (2017) 0.75
Prevalence of diabetes among men and women in China. N Engl J Med (2010) 19.98
HMDB: the Human Metabolome Database. Nucleic Acids Res (2007) 13.38
HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res (2008) 11.23
Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med (2013) 11.10
Duration of red-cell storage and complications after cardiac surgery. N Engl J Med (2008) 10.04
Severe hypoglycemia and risks of vascular events and death. N Engl J Med (2010) 8.54
Regional homogeneity approach to fMRI data analysis. Neuroimage (2004) 6.28
National survey of drug-resistant tuberculosis in China. N Engl J Med (2012) 6.28
REST: a toolkit for resting-state functional magnetic resonance imaging data processing. PLoS One (2011) 6.25
Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev (2006) 6.15
Factors other than glomerular filtration rate affect serum cystatin C levels. Kidney Int (2008) 5.90
Disrupted small-world networks in schizophrenia. Brain (2008) 5.10
Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Nat Med (2005) 5.09
Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography. Cereb Cortex (2008) 4.82
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting. Crit Care Med (2006) 4.59
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell (2009) 4.48
Predictors of cessation in a cohort of current and former smokers followed over 13 years. Nicotine Tob Res (2004) 3.78
Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. Neuroimage (2006) 3.77
BrainNet Viewer: a network visualization tool for human brain connectomics. PLoS One (2013) 3.74
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. Lancet (2008) 3.62
Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction. Biochem Biophys Res Commun (2009) 3.49
Intensive glucose control improves kidney outcomes in patients with type 2 diabetes. Kidney Int (2013) 3.42
Prevalence of smoking in China in 2010. N Engl J Med (2011) 3.38
Dynamic functional reorganization of the motor execution network after stroke. Brain (2010) 3.16
A longitudinal assessment of the impact of smoke-free worksite policies on tobacco use. Am J Public Health (2005) 3.05
Age- and gender-related differences in the cortical anatomical network. J Neurosci (2009) 3.04
Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib. Cancer Cell (2012) 2.96
Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial. Lancet Oncol (2013) 2.94
Altered resting-state functional connectivity patterns of anterior cingulate cortex in adolescents with attention deficit hyperactivity disorder. Neurosci Lett (2006) 2.93
Parcellation-dependent small-world brain functional networks: a resting-state fMRI study. Hum Brain Mapp (2009) 2.91
On-wire lithography. Science (2005) 2.81
Field evaluation of a rapid point-of-care assay for targeting antibiotic treatment for trachoma control: a comparative study. Lancet (2006) 2.65
Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. N Engl J Med (2014) 2.64
Revealing modular architecture of human brain structural networks by using cortical thickness from MRI. Cereb Cortex (2008) 2.62
Diffusion tensor tractography reveals abnormal topological organization in structural cortical networks in Alzheimer's disease. J Neurosci (2010) 2.60
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Autophagy (2011) 2.47
Application of hyperspectral imaging and chemometric calibrations for variety discrimination of maize seeds. Sensors (Basel) (2012) 2.46
Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Ann Thorac Surg (2006) 2.42
Reference values for continuous glucose monitoring in Chinese subjects. Diabetes Care (2009) 2.41
Access to low-taxed cigarettes deters smoking cessation attempts. Am J Public Health (2005) 2.33
Methods of the International Tobacco Control (ITC) China Survey. Tob Control (2009) 2.30
Disrupted brain connectivity networks in drug-naive, first-episode major depressive disorder. Biol Psychiatry (2011) 2.29
Benefits of rebuilding global marine fisheries outweigh costs. PLoS One (2012) 2.24
Spontaneous brain activity in the default mode network is sensitive to different resting-state conditions with limited cognitive load. PLoS One (2009) 2.22
Reconciling the high rates of preterm and postterm birth in the United States. Obstet Gynecol (2007) 2.21
On the convergence of ionospheric constrained precise point positioning (IC-PPP) based on undifferential uncombined raw GNSS observations. Sensors (Basel) (2013) 2.15
A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. Mol Cell (2008) 2.15
Altered small-world brain functional networks in children with attention-deficit/hyperactivity disorder. Hum Brain Mapp (2009) 2.15
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics. Lab Chip (2008) 2.11
The relative and combined ability of high-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide to predict cardiovascular events and death in patients with type 2 diabetes. Diabetes Care (2013) 2.07
Graph-based network analysis of resting-state functional MRI. Front Syst Neurosci (2010) 2.06
Graph theoretical analysis of functional brain networks: test-retest evaluation on short- and long-term resting-state functional MRI data. PLoS One (2011) 2.04
Detecting protein-protein interactions by Far western blotting. Nat Protoc (2007) 2.01
Severe maternal morbidity in Canada, 1991-2001. CMAJ (2005) 2.01
The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma. Mayo Clin Proc (2005) 2.00
Perioperative management and treatment for complications during and after peroral endoscopic myotomy (POEM) for esophageal achalasia (EA) (data from 119 cases). Surg Endosc (2012) 1.98
Coupling of functional connectivity and regional cerebral blood flow reveals a physiological basis for network hubs of the human brain. Proc Natl Acad Sci U S A (2013) 1.98
The human cerebrospinal fluid metabolome. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 1.96
Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma. Blood (2011) 1.95
Toward reliable characterization of functional homogeneity in the human brain: preprocessing, scan duration, imaging resolution and computational space. Neuroimage (2012) 1.92
Copper ion liquid-like thermoelectrics. Nat Mater (2012) 1.92
Tobacco-free electronic cigarettes and cigars deliver nicotine and generate concern. Tob Control (2007) 1.92
Graph-theoretical analysis reveals disrupted small-world organization of cortical thickness correlation networks in temporal lobe epilepsy. Cereb Cortex (2011) 1.91
Identification of bacteria using tandem mass spectrometry combined with a proteome database and statistical scoring. Anal Chem (2004) 1.89
The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma. J Hepatol (2008) 1.88
Frequency-dependent changes in the amplitude of low-frequency fluctuations in amnestic mild cognitive impairment: a resting-state fMRI study. Neuroimage (2010) 1.86
SlipChip. Lab Chip (2009) 1.84
Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. Diabetes Care (2008) 1.84
Identification of enriched driver gene alterations in subgroups of non-small cell lung cancer patients based on histology and smoking status. PLoS One (2012) 1.82
RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.80
Persistent effect of red cell transfusion on health-related quality of life after cardiac surgery. Ann Thorac Surg (2006) 1.80
Gray matter density and white matter integrity in pianists' brain: a combined structural and diffusion tensor MRI study. Neurosci Lett (2008) 1.79
Strokes after cardiac surgery and relationship to carotid stenosis. Arch Neurol (2009) 1.79
Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res (2010) 1.77
Brain gray matter deficits at 33-year follow-up in adults with attention-deficit/hyperactivity disorder established in childhood. Arch Gen Psychiatry (2011) 1.77
Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: a high-throughput tissue microarray and immunohistochemistry study. Hum Pathol (2003) 1.72
Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity. Cancer Res (2010) 1.71
Removal of tracheobronchial foreign bodies in adults using a flexible bronchoscope: experience with 200 cases in China. Intern Med (2012) 1.71
Red cell transfusion is associated with an increased risk for postoperative atrial fibrillation. Ann Thorac Surg (2006) 1.71
G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss. Bioinformatics (2006) 1.71
Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder. Neuroimage (2007) 1.69
Core/Shell semiconductor nanocrystals. Small (2009) 1.68
Review of recent advances in analytical techniques for the determination of neurotransmitters. Anal Chim Acta (2009) 1.68
GJB2 mutation spectrum in 2,063 Chinese patients with nonsyndromic hearing impairment. J Transl Med (2009) 1.66
Findings from 2010 Global Adult Tobacco Survey: implementation of MPOWER policy in China. Biomed Environ Sci (2010) 1.65
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer. Clin Exp Metastasis (2006) 1.64
Circulating bone morphogenetic protein-7 and transforming growth factor-β1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney Int (2012) 1.63
Diffusion tensor tractography reveals disrupted topological efficiency in white matter structural networks in multiple sclerosis. Cereb Cortex (2011) 1.62
Knockdown of long non-coding RNA HOTAIR suppresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancer. Int J Biol Sci (2013) 1.62
Discrete neuroanatomical networks are associated with specific cognitive abilities in old age. J Neurosci (2011) 1.61
Dopamine depletion impairs frontostriatal functional connectivity during a set-shifting task. J Neurosci (2008) 1.60
Synthesis of CeO2 nanorods via ultrasonication assisted by polyethylene glycol. Inorg Chem (2007) 1.60
Functional and structural connectivity between the perigenual anterior cingulate and amygdala in bipolar disorder. Biol Psychiatry (2009) 1.59
Out of Tibet: Pliocene woolly rhino suggests high-plateau origin of Ice Age megaherbivores. Science (2011) 1.58
Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: a meta-analysis of randomized controlled trials. Endocrine (2014) 1.58
Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancer. Clin Cancer Res (2009) 1.56
Protein sequencing by mass analysis of polypeptide ladders after controlled protein hydrolysis. Nat Biotechnol (2004) 1.56
Disrupted functional brain connectome in individuals at risk for Alzheimer's disease. Biol Psychiatry (2012) 1.56
Whole brain white matter changes revealed by multiple diffusion metrics in multiple sclerosis: a TBSS study. Eur J Radiol (2011) 1.55