Shaji Kumar

Author PubWeight™ 151.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell 2007 7.24
2 Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Blood 2005 5.82
3 Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study. Blood 2009 5.69
4 Clonal competition with alternating dominance in multiple myeloma. Blood 2012 4.39
5 New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes. J Clin Oncol 2012 3.35
6 Mayo clinic consensus statement for the use of bisphosphonates in multiple myeloma. Mayo Clin Proc 2006 2.88
7 Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013. Mayo Clin Proc 2013 2.59
8 Treatment of newly diagnosed multiple myeloma based on Mayo Stratification of Myeloma and Risk-adapted Therapy (mSMART): consensus statement. Mayo Clin Proc 2007 2.55
9 Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma. J Clin Oncol 2009 2.50
10 Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease. Blood 2011 2.45
11 Stem cell transplantation in multiple myeloma: impact of response failure with thalidomide or lenalidomide induction. Blood 2010 2.40
12 Long-term results of response to therapy, time to progression, and survival with lenalidomide plus dexamethasone in newly diagnosed myeloma. Mayo Clin Proc 2007 2.34
13 Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling. Cancer Res 2007 2.19
14 Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients. Blood 2009 2.12
15 Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3. Blood 2011 2.07
16 Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application. Br J Haematol 2005 1.99
17 Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin Proc 2009 1.96
18 Trends in utilization and outcomes of autologous transplantation as early therapy for multiple myeloma. Biol Blood Marrow Transplant 2013 1.88
19 Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2. Blood 2009 1.86
20 Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone. Blood 2009 1.86
21 Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma. Blood 2004 1.82
22 Salvage second hematopoietic cell transplantation in myeloma. Biol Blood Marrow Transplant 2013 1.80
23 Idiopathic systemic capillary leak syndrome (Clarkson's disease): the Mayo clinic experience. Mayo Clin Proc 2010 1.80
24 Seliciclib (CYC202 or R-roscovitine), a small-molecule cyclin-dependent kinase inhibitor, mediates activity via down-regulation of Mcl-1 in multiple myeloma. Blood 2005 1.79
25 Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells. Cancer Res 2006 1.72
26 Early reduction of serum-free light chains associates with renal recovery in myeloma kidney. J Am Soc Nephrol 2011 1.57
27 NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on the Epidemiology and Natural History of Relapse following Allogeneic Cell Transplantation. Biol Blood Marrow Transplant 2010 1.56
28 Troponin T level as an exclusion criterion for stem cell transplantation in light-chain amyloidosis. Leuk Lymphoma 2008 1.54
29 Long-term outcomes of patients with light chain amyloidosis (AL) after renal transplantation with or without stem cell transplantation. Nephrol Dial Transplant 2011 1.51
30 The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma. Proc Natl Acad Sci U S A 2006 1.46
31 VEGF induces Mcl-1 up-regulation and protects multiple myeloma cells against apoptosis. Blood 2004 1.46
32 The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome. Blood 2011 1.46
33 Evidence for cytogenetic and fluorescence in situ hybridization risk stratification of newly diagnosed multiple myeloma in the era of novel therapie. Mayo Clin Proc 2010 1.34
34 Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience. Blood 2012 1.32
35 Cardiac amyloidosis: a practical approach to diagnosis and management. Am J Med 2011 1.31
36 Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model. Clin Cancer Res 2007 1.30
37 Transplantation for amyloidosis. Curr Opin Oncol 2007 1.29
38 FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance. Cancer Res 2005 1.25
39 Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis. Blood 2005 1.23
40 Plasma cell labeling index. Methods Mol Med 2005 1.22
41 Impact of optimal follow-up of monoclonal gammopathy of undetermined significance on early diagnosis and prevention of myeloma-related complications. Blood 2010 1.13
42 Autologous stem cell transplant in 716 patients with multiple myeloma: low treatment-related mortality, feasibility of outpatient transplant, and effect of a multidisciplinary quality initiative. Mayo Clin Proc 2008 1.13
43 Clinical implication of centrosome amplification in plasma cell neoplasm. Blood 2005 1.11
44 Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma. Am J Hematol 2010 1.10
45 Use of nonclonal serum immunoglobulin free light chains to predict overall survival in the general population. Mayo Clin Proc 2012 1.09
46 Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma. Am J Hematol 2009 1.08
47 The importance of bone marrow examination in determining complete response to therapy in patients with multiple myeloma. Blood 2009 1.07
48 An oncolytic measles virus engineered to enter cells through the CD20 antigen. Mol Ther 2003 1.07
49 Progression in smoldering Waldenstrom macroglobulinemia: long-term results. Blood 2012 1.06
50 Autologous stem cell transplant after heart transplant for light chain (Al) amyloid cardiomyopathy. J Heart Lung Transplant 2008 1.03
51 Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics. Clin Cancer Res 2008 1.02
52 Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression. Leuk Res 2006 1.02
53 Review: extramedullary disease in multiple myeloma. Clin Adv Hematol Oncol 2009 1.01
54 Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway. Oncogene 2005 0.97
55 Differential cytopathology and kinetics of measles oncolysis in two primary B-cell malignancies provides mechanistic insights. Mol Ther 2011 0.96
56 Cost-effectiveness analysis of a risk-adapted algorithm of plerixafor use for autologous peripheral blood stem cell mobilization. Biol Blood Marrow Transplant 2012 0.95
57 Differential expression of vascular endothelial growth factors and their receptors in multiple myeloma. Haematologica 2006 0.95
58 Efficacy of bortezomib as first-line treatment for patients with multiple myeloma. Clin Med Insights Oncol 2013 0.95
59 Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo. Blood 2005 0.95
60 TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells. Am J Hematol 2010 0.95
61 SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma. Blood 2005 0.95
62 Clinical features of patients with immunoglobulin light chain amyloidosis (AL) with vascular-limited deposition in the kidney. Nephrol Dial Transplant 2011 0.94
63 Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease. Nephrol Dial Transplant 2010 0.94
64 Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis. Haematologica 2009 0.93
65 Anti-myeloma activity of Akt inhibition is linked to the activation status of PI3K/Akt and MEK/ERK pathway. PLoS One 2012 0.93
66 Incidence, clinical course, and prognosis of secondary monoclonal gammopathy of undetermined significance in patients with multiple myeloma. Blood 2011 0.93
67 Treatment for high-risk smoldering myeloma. N Engl J Med 2013 0.92
68 Idiotype-pulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival. Am J Hematol 2009 0.92
69 Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors. Oncogene 2005 0.91
70 Expanded safety experience with lenalidomide plus dexamethasone in relapsed or refractory multiple myeloma. Br J Haematol 2009 0.91
71 Outcome of patients with IgD and IgM multiple myeloma undergoing autologous hematopoietic stem cell transplantation: a retrospective CIBMTR study. Clin Lymphoma Myeloma Leuk 2010 0.90
72 Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition. Mayo Clin Proc 2012 0.90
73 Efficacy of retreatment with immunomodulatory drugs (IMiDs) in patients receiving IMiDs for initial therapy of newly diagnosed multiple myeloma. Blood 2011 0.90
74 High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis. N Engl J Med 2008 0.90
75 Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin. Am J Hematol 2011 0.90
76 Therapy-related myelodysplastic syndrome/acute leukemia after multiple myeloma in the era of novel agents. Leuk Lymphoma 2014 0.90
77 R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells. Exp Hematol 2008 0.90
78 The significance of monoclonal gammopathy of undetermined significance. Haematologica 2009 0.88
79 Solitary plasmacytoma: is radiation therapy sufficient? Am J Hematol 2008 0.88
80 Serum immunoglobulin free light chain measurements and heavy chain isotype usage provide insight into disease biology in patients with POEMS syndrome. Am J Hematol 2010 0.87
81 Lenalidomide plus dexamethasone vs. lenalidomide plus melphalan and prednisone: a retrospective study in newly diagnosed elderly myeloma. Eur J Haematol 2010 0.86
82 Plasma levels of tumour necrosis factor alpha and interleukin-6 predict progression-free survival following thalidomide therapy in patients with previously untreated multiple myeloma. Br J Haematol 2003 0.85
83 Urinary albumin excretion patterns of patients with cast nephropathy and other monoclonal gammopathy-related kidney diseases. Clin J Am Soc Nephrol 2012 0.85
84 A detailed evaluation of the current renal response criteria in AL amyloidosis: is it time for a revision? Haematologica 2013 0.85
85 Long-term results of single-agent thalidomide as initial therapy for asymptomatic (smoldering or indolent) myeloma. Am J Hematol 2010 0.85
86 Emerging therapeutic paradigms to target the dysregulated Janus kinase/signal transducer and activator of transcription pathway in hematological malignancies. Leuk Lymphoma 2014 0.84
87 Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma. Am J Hematol 2013 0.83
88 The investigational proteasome inhibitor ixazomib for the treatment of multiple myeloma. Future Oncol 2015 0.83
89 Impact of high-risk classification by FISH: an eastern cooperative oncology group (ECOG) study E4A03. Br J Haematol 2011 0.83
90 Hematopoietic recovery kinetics predicts for poor CD34+ cell mobilization after cyclophosphamide chemotherapy in multiple myeloma. Am J Hematol 2011 0.83
91 Successful treatment of scleromyxedema with autologous peripheral blood stem cell transplantation. Arch Dermatol 2005 0.83
92 Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis. Br J Haematol 2013 0.82
93 Acute renal failure secondary to severe type I cryoglobulinemia following rituximab therapy for Waldenström's macroglobulinemia. Clin Exp Nephrol 2008 0.81
94 Low levels of interleukin-1 receptor antagonist (IL-1RA) predict engraftment syndrome after autologous stem cell transplantation in POEMS syndrome and other plasma cell neoplasms. Biol Blood Marrow Transplant 2013 0.80
95 Cell Trafficking in Multiple Myeloma. Open J Hematol 2012 0.79
96 Treatment trade-offs in myeloma: A survey of consecutive patients about contemporary maintenance strategies. Cancer 2013 0.79
97 Current advances in non-proteasome inhibitor-based approaches to the treatment of relapsed/refractory multiple myeloma. Oncology (Williston Park) 2011 0.78
98 Evaluation of pretransplant factors predicting cardiac dysfunction following high-dose melphalan conditioning and autologous peripheral blood stem cell transplantation. Eur J Haematol 2012 0.78
99 Immunoglobulin m monoclonal gammopathy of undetermined significance and smoldering Waldenström macroglobulinemia. Clin Lymphoma Myeloma Leuk 2013 0.78
100 Mobilization and transplantation patterns of autologous hematopoietic stem cells in multiple myeloma and non-Hodgkin lymphoma. Cancer Control 2015 0.77
101 On appetite and its loss. J Clin Oncol 2003 0.77
102 Acute kidney injury during leukocyte engraftment after autologous stem cell transplantation in patients with light-chain amyloidosis. Am J Hematol 2011 0.77
103 IgM monoclonal gammopathy of undetermined significance (MGUS) and smoldering Waldenström's macroglobulinemia (SWM). Clin Lymphoma Myeloma Leuk 2011 0.77
104 Initial treatment of transplant-eligible patients in multiple myeloma. Expert Rev Hematol 2014 0.76
105 Factors associated with favorable outcome after allogeneic hematopoietic stem cell transplantation for multiple myeloma. Leuk Lymphoma 2009 0.75
106 Reply to S. Girnius et al. J Clin Oncol 2013 0.75
107 Conflicts of interest, authorship, and disclosures in industry-related scientific publications. Mayo Clin Proc 2010 0.75
108 Differences in the distribution of cytogenetic subtypes between multiple myeloma patients with and without a family history of monoclonal gammopathy and multiple myeloma. Eur J Haematol 2013 0.75
109 Candidate genes of Waldenström's macroglobulinemia: current evidence and research. Appl Clin Genet 2013 0.75
110 Residual serum monoclonal protein predicts progression-free survival in patients with previously untreated multiple myeloma. Cancer 2010 0.75
111 A novel report of cig-FISH and cytogenetics in POEMS syndrome. Am J Hematol 2008 0.75
112 Impact of dexamethasone responsiveness on long term outcome in patients with newly diagnosed multiple myeloma. Br J Haematol 2009 0.75
113 Genetic variants in DNA repair pathways are not associated with disease progression among multiple myeloma patients. Leuk Res 2013 0.75
114 Activity of bortezomib administered once every 3 weeks for treatment of relapsed multiple myeloma. Leuk Lymphoma 2009 0.75
115 Corrigendum: Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients. Nat Commun 2015 0.75
116 An unusual neurological complication of light chain amyloidosis. Br J Haematol 2009 0.75