| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Synthesis and evaluation of [11C]XR9576 to assess the function of drug efflux transporters using PET.
|
Ann Nucl Med
|
2010
|
1.16
|
|
2
|
Evaluation of limiting brain penetration related to P-glycoprotein and breast cancer resistance protein using [(11)C]GF120918 by PET in mice.
|
Mol Imaging Biol
|
2011
|
1.06
|
|
3
|
PET imaging of lung inflammation with [18F]FEDAC, a radioligand for translocator protein (18 kDa).
|
PLoS One
|
2012
|
0.93
|
|
4
|
Synthesis and evaluation of novel radioligands for positron emission tomography imaging of metabotropic glutamate receptor subtype 1 (mGluR1) in rodent brain.
|
J Med Chem
|
2012
|
0.93
|
|
5
|
In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [(11)C]gefitinib.
|
Nucl Med Biol
|
2009
|
0.91
|
|
6
|
Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 1.
|
Bioorg Med Chem Lett
|
2011
|
0.91
|
|
7
|
Synthesis and in vivo evaluation of ¹⁸F-fluoroethyl GF120918 and XR9576 as positron emission tomography probes for assessing the function of drug efflux transporters.
|
Bioorg Med Chem
|
2010
|
0.90
|
|
8
|
Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM.
|
Eur J Nucl Med Mol Imaging
|
2011
|
0.88
|
|
9
|
Radiosynthesis and evaluation of [11C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 1.
|
Nucl Med Biol
|
2010
|
0.87
|
|
10
|
Translocator protein (18 kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease.
|
J Hepatol
|
2012
|
0.87
|
|
11
|
[11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma.
|
Mol Imaging Biol
|
2009
|
0.86
|
|
12
|
Development of N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[11C]methylbenzamide for positron emission tomography imaging of metabotropic glutamate 1 receptor in monkey brain.
|
J Med Chem
|
2012
|
0.85
|
|
13
|
Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.
|
Bioorg Med Chem
|
2010
|
0.83
|
|
14
|
[11C]sorafenib: radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice.
|
Bioorg Med Chem Lett
|
2011
|
0.83
|
|
15
|
Evaluation of N-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.
|
Synapse
|
2009
|
0.81
|
|
16
|
In vivo measurement of the affinity and density of metabotropic glutamate receptor subtype 1 in rat brain using 18F-FITM in small-animal PET.
|
J Nucl Med
|
2012
|
0.80
|
|
17
|
[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain.
|
Bioorg Med Chem Lett
|
2009
|
0.80
|
|
18
|
Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo- isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains.
|
J Neurochem
|
2011
|
0.80
|
|
19
|
[(11)C]DAC-PET for noninvasively monitoring neuroinflammation and immunosuppressive therapy efficacy in rat experimental autoimmune encephalomyelitis model.
|
J Neuroimmune Pharmacol
|
2011
|
0.79
|
|
20
|
PET study using [11C]FTIMD with ultra-high specific activity to evaluate I2-imidazoline receptors binding in rat brains.
|
Nucl Med Biol
|
2011
|
0.79
|
|
21
|
Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor.
|
Bioorg Med Chem Lett
|
2010
|
0.79
|
|
22
|
Evaluation of the P-glycoprotein- and breast cancer resistance protein-mediated brain penetration of 11C-labeled topotecan using small-animal positron emission tomography.
|
Nucl Med Biol
|
2011
|
0.78
|
|
23
|
Development of [(11)C]MFTC for PET imaging of fatty acid amide hydrolase in rat and monkey brains.
|
ACS Chem Neurosci
|
2014
|
0.78
|
|
24
|
Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.
|
J Neurochem
|
2014
|
0.78
|
|
25
|
Biodistribution and metabolism of the anti-influenza drug [11C]oseltamivir and its active metabolite [11C]Ro 64-0802 in mice.
|
Nucl Med Biol
|
2009
|
0.78
|
|
26
|
Determination of radioactivity in infant, juvenile and adult rat brains after injection of anti-influenza drug [¹¹C]oseltamivir using PET and autoradiography.
|
Neurosci Lett
|
2011
|
0.78
|
|
27
|
Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.
|
Org Biomol Chem
|
2014
|
0.78
|
|
28
|
PET study on mice bearing human colon adenocarcinoma cells using [11C]GF120918, a dual radioligand for P-glycoprotein and breast cancer resistance protein.
|
Nucl Med Commun
|
2010
|
0.77
|
|
29
|
Synthesis, metabolite analysis, and in vivo evaluation of [(11)C]irinotecan as a novel positron emission tomography (PET) probe.
|
Nucl Med Biol
|
2013
|
0.77
|
|
30
|
In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC.
|
Nucl Med Biol
|
2010
|
0.77
|
|
31
|
Binding potential of (E)-[¹¹C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its ¹¹C-labelled Z-isomer.
|
Nucl Med Biol
|
2013
|
0.77
|
|
32
|
Radiosynthesis of three [11C]ureido-substituted benzenesulfonamides as PET probes for carbonic anhydrase IX in tumors.
|
Bioorg Med Chem Lett
|
2011
|
0.76
|
|
33
|
Synthesis and evaluation of novel carbon-11 labeled oxopurine analogues for positron emission tomography imaging of translocator protein (18 kDa) in peripheral organs.
|
J Med Chem
|
2011
|
0.76
|
|
34
|
Imaging of I2-imidazoline receptors by small-animal PET using 2-(3-fluoro-[4-11C]tolyl)-4,5-dihydro-1H-imidazole ([11C]FTIMD).
|
Nucl Med Biol
|
2010
|
0.76
|
|
35
|
Synthesis and evaluation of PET probes for the imaging of I2 imidazoline receptors in peripheral tissues.
|
Nucl Med Biol
|
2011
|
0.76
|
|
36
|
Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe (18) F-FITM.
|
Int J Cancer
|
2014
|
0.75
|
|
37
|
Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker α5β1 Integrin.
|
Biol Pharm Bull
|
2015
|
0.75
|
|
38
|
Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.
|
J Med Chem
|
2015
|
0.75
|
|
39
|
In vivo evaluation of limiting brain penetration of probes for α(2C)-adrenoceptor using small-animal positron emission tomography.
|
ACS Chem Neurosci
|
2010
|
0.75
|
|
40
|
Synthesis and evaluation of [11C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain.
|
EJNMMI Res
|
2013
|
0.75
|
|
41
|
Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor.
|
J Radiat Res
|
2009
|
0.75
|
|
42
|
[2-14C]Thymidine incorporation activity of stem cells in either tumor or cradle tissues in a normal or transplanted animals.
|
Eur J Drug Metab Pharmacokinet
|
2005
|
0.75
|
|
43
|
Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.
|
Bioorg Med Chem
|
2013
|
0.75
|
|
44
|
Utilization of [11C]phosgene for radiosynthesis of N-(2-{3-[3,5-bis(trifluoromethyl)]phenyl[11C]ureido}ethyl)glycyrrhetinamide, an inhibitory agent for proteasome and kinase in tumors.
|
Bioorg Med Chem Lett
|
2012
|
0.75
|
|
45
|
Synchronous evaluation of toxico- and pharmaco-dynamics of yttrium-90 by a novel autoradiographic procedure.
|
Regul Toxicol Pharmacol
|
2004
|
0.75
|