Published in Am J Physiol Cell Physiol on February 11, 2009
Caco-2 cell acquisition of dietary iron(III) invokes a nanoparticulate endocytic pathway. PLoS One (2013) 1.56
Intestinal absorption of water-soluble vitamins in health and disease. Biochem J (2011) 1.40
Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport. Am J Physiol Renal Physiol (2010) 1.07
Inhibition of intestinal biotin absorption by chronic alcohol feeding: cellular and molecular mechanisms. Am J Physiol Gastrointest Liver Physiol (2010) 1.02
Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2011) 0.95
Recent advances in transport of water-soluble vitamins in organs of the digestive system: a focus on the colon and the pancreas. Am J Physiol Gastrointest Liver Physiol (2013) 0.91
Association of PDZ-containing protein PDZD11 with the human sodium-dependent multivitamin transporter. Am J Physiol Gastrointest Liver Physiol (2010) 0.91
Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter. J Biol Chem (2013) 0.87
Role of the putative N-glycosylation and PKC-phosphorylation sites of the human sodium-dependent multivitamin transporter (hSMVT) in function and regulation. Biochim Biophys Acta (2011) 0.86
Structure-function activity of the human sodium-dependent multivitamin transporter: role of His¹¹⁵ and His²⁵⁴. Am J Physiol Cell Physiol (2010) 0.85
Chronic alcohol exposure negatively impacts the physiological and molecular parameters of the renal biotin reabsorption process. Am J Physiol Renal Physiol (2011) 0.81
Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells. Am J Physiol Gastrointest Liver Physiol (2009) 0.81
Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects. PLoS One (2013) 0.79
Role of the sodium-dependent multivitamin transporter (SMVT) in the maintenance of intestinal mucosal integrity. Am J Physiol Gastrointest Liver Physiol (2016) 0.78
Interaction of α-Lipoic Acid with the Human Na+/Multivitamin Transporter (hSMVT). J Biol Chem (2015) 0.77
Human Organic Solute Transporter (hOST): protein interaction and membrane sorting process. Int J Biochem Mol Biol (2012) 0.77
Cys(294) is essential for the function of the human sodium-dependent multivitamin transporter. Biochim Biophys Acta (2011) 0.76
Mutations in SLC5A6 associated with brain, immune, bone, and intestinal dysfunction in a young child. Hum Genet (2016) 0.75
Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter:A role for casein kinase 2-mediated pathway. Am J Physiol Cell Physiol (2017) 0.75
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res (2003) 15.74
Brefeldin A: insights into the control of membrane traffic and organelle structure. J Cell Biol (1992) 13.15
Dissection of the Golgi complex. I. Monensin inhibits the transport of viral membrane proteins from medial to trans Golgi cisternae in baby hamster kidney cells infected with Semliki Forest virus. J Cell Biol (1983) 4.20
Dynactin is required for bidirectional organelle transport. J Cell Biol (2003) 3.04
Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity. Biochim Biophys Acta (1990) 2.93
Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170. Mol Biol Cell (1999) 2.72
Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein. Nat Cell Biol (2000) 2.37
Cellular localization and trafficking of the human ABCA1 transporter. J Biol Chem (2001) 2.26
Mutations in the middle of the transmembrane domain reverse the polarity of transport of the influenza virus hemagglutinin in MDCK epithelial cells. J Cell Biol (1998) 1.89
YRRL motifs in the cytoplasmic domain of the thrombopoietin receptor regulate receptor internalization and degradation. Blood (2008) 1.86
The epithelial Na+ channel: cell surface insertion and retrieval in Na+ homeostasis and hypertension. Endocr Rev (2002) 1.79
Biotin status assessed longitudinally in pregnant women. J Nutr (1997) 1.76
Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. J Biol Chem (2000) 1.73
Uptake, localization, and noncarboxylase roles of biotin. Annu Rev Nutr (2005) 1.69
Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. Am J Physiol Cell Physiol (2007) 1.64
The cytoplasmic tail of rhodopsin acts as a novel apical sorting signal in polarized MDCK cells. J Cell Biol (1998) 1.51
The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem (2004) 1.40
Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2. Am J Physiol Cell Physiol (2006) 1.40
Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization. J Biol Chem (1999) 1.35
Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter. Arch Biochem Biophys (1999) 1.32
PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes. Am J Physiol Cell Physiol (2005) 1.31
PERIPHERAL NEUROPATHY OF THE ALCOHOLIC: I, AETIOLOGICAL ROLE OF ANEURIN AND OTHER B-COMPLEX VITAMINS. Br Med J (1964) 1.31
Vitamin status in patients with inflammatory bowel disease. Am J Gastroenterol (1989) 1.27
Inheritable biotin-treatable disorders and associated phenomena. Annu Rev Nutr (1986) 1.21
Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system. Am J Physiol Gastrointest Liver Physiol (2003) 1.19
Compartmentalization of protein traffic in insulin-sensitive cells. Am J Physiol (1996) 1.18
Impaired biotin status in anticonvulsant therapy. Ann Neurol (1982) 1.17
The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core. J Biol Chem (2002) 1.15
Selective inhibition of protein targeting to the apical domain of MDCK cells by brefeldin A. J Cell Biol (1992) 1.12
The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting. J Biol Chem (2004) 1.11
Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: A study of the hSMVT system. Am J Physiol Gastrointest Liver Physiol (2006) 1.11
A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia. J Biol Chem (2004) 1.07
Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. J Biol Chem (2005) 1.04
Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat. Am J Physiol Renal Physiol (2003) 1.04
Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. J Am Soc Nephrol (2005) 1.03
Identification of sorting determinants in the C-terminal cytoplasmic tails of the gamma-aminobutyric acid transporters GAT-2 and GAT-3. J Biol Chem (1998) 1.03
A 14-amino acid sequence with a beta-turn structure is required for apical membrane sorting of the rat ileal bile acid transporter. J Biol Chem (2002) 1.01
Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects. Am J Physiol Renal Physiol (2004) 0.96
Biotin status of epileptics. Ann N Y Acad Sci (1985) 0.95
Evidence for the existence of a carrier-mediated folate uptake mechanism in human colonic luminal membranes. Am J Physiol (1997) 0.94
Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery. Mol Pharm (2006) 0.93
Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients. Arch Dis Child (1975) 0.89
Seborrheic dermatitis of infants and Leiners's disease: a biotin deficiency. J Pediatr (1957) 0.87
Vitamins and alcoholism. IV. Thiamin. Int J Vitam Nutr Res (1980) 0.87
Requirement of a leucine residue for (apical) membrane expression of type IIb NaPi cotransporters. Proc Natl Acad Sci U S A (2000) 0.85
Molecular characteristics of phosphate transporters and their regulation. Exp Nephrol (2000) 0.80
Cytosolic COOH terminus of the peptide transporter PEPT2 is involved in apical membrane localization of the protein. Am J Physiol Cell Physiol (2005) 0.79
TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am J Physiol Gastrointest Liver Physiol (2004) 3.12
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. J Cell Biol (2009) 3.04
Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression. Am J Physiol Gastrointest Liver Physiol (2005) 2.45
IL-1beta causes an increase in intestinal epithelial tight junction permeability. J Immunol (2007) 1.96
Isolation and functional characterization of the actin binding region in the tight junction protein ZO-1. FASEB J (2002) 1.86
Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J Immunol (2008) 1.83
Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier. Am J Physiol Gastrointest Liver Physiol (2006) 1.82
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells. J Biol Chem (2011) 1.67
Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. Am J Physiol Cell Physiol (2007) 1.64
TNF-α modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1. Am J Pathol (2013) 1.60
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles. J Biol Chem (2009) 1.42
MicroRNA regulation of intestinal epithelial tight junction permeability. Gastroenterology (2011) 1.41
Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2. Am J Physiol Cell Physiol (2006) 1.40
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg. J Biol Chem (2011) 1.28
Evolution of postmenopausal hormone therapy between 2002 and 2009. Menopause (2012) 1.26
Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. Am J Physiol Gastrointest Liver Physiol (2003) 1.26
Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals. Cell Calcium (2010) 1.26
A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: subversion of flatworm regenerative polarity. PLoS Negl Trop Dis (2009) 1.26
Characterization of the 5'-regulatory region of the human thiamin transporter SLC19A3: in vitro and in vivo studies. Am J Physiol Gastrointest Liver Physiol (2004) 1.23
Developmental maturation of intestinal and renal thiamin uptake: studies in wild-type and transgenic mice carrying human THTR-1 and 2 promoters. J Cell Physiol (2006) 1.23
Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability. Am J Physiol Gastrointest Liver Physiol (2006) 1.23
Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14. Am J Pathol (2012) 1.22
Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system. Am J Physiol Gastrointest Liver Physiol (2003) 1.19
Expression and promoter analysis of SLC19A2 in the human intestine. Biochim Biophys Acta (2002) 1.18
Impaired intestinal vitamin B1 (thiamin) uptake in thiamin transporter-2-deficient mice. Gastroenterology (2009) 1.17
Biotin supply affects rates of cell proliferation, biotinylation of carboxylases and histones, and expression of the gene encoding the sodium-dependent multivitamin transporter in JAr choriocarcinoma cells. Eur J Nutr (2004) 1.14
Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling. J Biol Chem (2012) 1.13
Thiamin uptake by the human-derived renal epithelial (HEK-293) cells: cellular and molecular mechanisms. Am J Physiol Renal Physiol (2006) 1.12
Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: A study of the hSMVT system. Am J Physiol Gastrointest Liver Physiol (2006) 1.11
Effect of folate oversupplementation on folate uptake by human intestinal and renal epithelial cells. Am J Clin Nutr (2007) 1.10
Timing in cellular Ca2+ signaling. Curr Biol (2008) 1.10
IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway. Am J Pathol (2010) 1.08
Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport. Am J Physiol Renal Physiol (2010) 1.07
A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia. J Biol Chem (2004) 1.07
LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-kappaB. Cell Stress Chaperones (2009) 1.06
Cellular and molecular mechanisms of heat stress-induced up-regulation of occludin protein expression: regulatory role of heat shock factor-1. Am J Pathol (2008) 1.05
Mechanism of glucocorticoid regulation of the intestinal tight junction barrier. Am J Physiol Gastrointest Liver Physiol (2006) 1.05
Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. J Biol Chem (2005) 1.04
Cell biology of the human thiamine transporter-1 (hTHTR1). Intracellular trafficking and membrane targeting mechanisms. J Biol Chem (2002) 1.04
Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process. Am J Physiol Gastrointest Liver Physiol (2010) 1.04
Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat. Am J Physiol Renal Physiol (2003) 1.04
Molecular characterization of a novel intracellular ADP-ribosyl cyclase. PLoS One (2007) 1.03
Mechanism of interferon-gamma-induced increase in T84 intestinal epithelial tight junction. J Interferon Cytokine Res (2009) 1.03
Characterization of the 5' regulatory region of the human sodium-dependent multivitamin transporter, hSMVT. Biochim Biophys Acta (2002) 1.02
Inhibition of intestinal biotin absorption by chronic alcohol feeding: cellular and molecular mechanisms. Am J Physiol Gastrointest Liver Physiol (2010) 1.02
In vitro and in vivo characterization of the minimal promoter region of the human thiamin transporter SLC19A2. Am J Physiol Cell Physiol (2003) 1.01
Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function. Biochem J (2003) 1.01
Thiamin uptake by pancreatic acinar cells: effect of chronic alcohol feeding/exposure. Am J Physiol Gastrointest Liver Physiol (2011) 1.01
Relative contribution of THTR-1 and THTR-2 in thiamin uptake by pancreatic acinar cells: studies utilizing Slc19a2 and Slc19a3 knockout mouse models. Am J Physiol Gastrointest Liver Physiol (2011) 1.00
Differentiation-dependent up-regulation of intestinal thiamin uptake: cellular and molecular mechanisms. J Biol Chem (2005) 1.00
Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells. Am J Physiol Gastrointest Liver Physiol (2008) 0.98
Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. Biochim Biophys Acta (2011) 0.98
The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels. Cell Calcium (2011) 0.97
Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. J Biol Chem (2004) 0.96
Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects. Am J Physiol Renal Physiol (2004) 0.96
Adaptive regulation of intestinal thiamin uptake: molecular mechanism using wild-type and transgenic mice carrying hTHTR-1 and -2 promoters. Am J Physiol Gastrointest Liver Physiol (2005) 0.96
Role of HDL dysfunction in end-stage renal disease: a double-edged sword. J Ren Nutr (2013) 0.96
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. Nephrol Dial Transplant (2010) 0.96
Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2011) 0.95
Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria. Mol Pharmacol (2009) 0.95
IP3 receptor activity is differentially regulated in endoplasmic reticulum subdomains during oocyte maturation. Curr Biol (2005) 0.95
Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier. Am J Physiol Gastrointest Liver Physiol (2009) 0.95
Cellular and molecular mechanisms that mediate basal and tumour necrosis factor-alpha-induced regulation of myosin light chain kinase gene activity. J Cell Mol Med (2008) 0.95
Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning. J Neurosci (2011) 0.94
Mechanism of IL-1β modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation. J Immunol (2013) 0.94
Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo. Am J Physiol Cell Physiol (2006) 0.93
Pancreatic beta cells and islets take up thiamin by a regulated carrier-mediated process: studies using mice and human pancreatic preparations. Am J Physiol Gastrointest Liver Physiol (2009) 0.93
N-Glycosylation is required for Na+-dependent vitamin C transporter functionality. Biochem Biophys Res Commun (2008) 0.93
Pharmacological and functional genetic assays to manipulate regeneration of the planarian Dugesia japonica. J Vis Exp (2011) 0.93
The Xenopus oocyte: a single-cell model for studying Ca2+ signaling. Cold Spring Harb Protoc (2013) 0.93
Nuclear microinjection to assess how heterologously expressed proteins impact Ca2+ signals in Xenopus oocytes. Cold Spring Harb Protoc (2013) 0.92
Stromal cells induce Th17 during Helicobacter pylori infection and in the gastric tumor microenvironment. PLoS One (2013) 0.92
Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum. J Biol Chem (2013) 0.92
Association of PDZ-containing protein PDZD11 with the human sodium-dependent multivitamin transporter. Am J Physiol Gastrointest Liver Physiol (2010) 0.91
Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. Am J Physiol Cell Physiol (2007) 0.90
Conditional knockout of the Slc5a6 gene in mouse intestine impairs biotin absorption. Am J Physiol Gastrointest Liver Physiol (2012) 0.90
Folate uptake in the human intestine: promoter activity and effect of folate deficiency. J Cell Physiol (2003) 0.90
Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans. Am J Physiol Cell Physiol (2007) 0.89
Mechanism of interleukin-1β induced-increase in mouse intestinal permeability in vivo. J Interferon Cytokine Res (2012) 0.89
Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells. J Biol Chem (2002) 0.89