| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community.
|
Circulation
|
2009
|
2.05
|
|
2
|
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
|
Cardiovasc Res
|
2003
|
1.78
|
|
3
|
Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis.
|
Circ Res
|
2008
|
1.65
|
|
4
|
Independent association of urinary F2-isoprostanes with survival in pulmonary arterial hypertension.
|
Chest
|
2012
|
1.48
|
|
5
|
Association of the endogenous nitric oxide synthase inhibitor ADMA with carotid artery intimal media thickness in the Framingham Heart Study offspring cohort.
|
Stroke
|
2009
|
1.47
|
|
6
|
Aliskiren accumulation in the kidney: no major role for binding to renin or prorenin.
|
J Hypertens
|
2013
|
1.44
|
|
7
|
Postocclusive reactive hyperemia inversely correlates with urinary 15-F2t-isoprostane levels in systemic sclerosis.
|
Free Radic Biol Med
|
2006
|
1.42
|
|
8
|
Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay.
|
Clin Chem Lab Med
|
2004
|
1.41
|
|
9
|
Quantification of arginine and its mono- and dimethylated analogs NMMA, ADMA and SDMA in biological fluids by LC-MS/MS: Is LC superfluous?
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2009
|
1.39
|
|
10
|
Asymmetric dimethylarginine is an independent risk factor for coronary heart disease: results from the multicenter Coronary Artery Risk Determination investigating the Influence of ADMA Concentration (CARDIAC) study.
|
Am Heart J
|
2006
|
1.38
|
|
11
|
Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality--an update on patient populations with a wide range of cardiovascular risk.
|
Pharmacol Res
|
2009
|
1.31
|
|
12
|
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.
|
Arterioscler Thromb Vasc Biol
|
2011
|
1.19
|
|
13
|
Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effects.
|
Arterioscler Thromb Vasc Biol
|
2006
|
1.17
|
|
14
|
Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data.
|
Clin Chem
|
2007
|
1.16
|
|
15
|
The pathophysiology of erectile dysfunction related to endothelial dysfunction and mediators of vascular function.
|
Vasc Med
|
2002
|
1.15
|
|
16
|
Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease.
|
J Am Coll Cardiol
|
2004
|
1.12
|
|
17
|
Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine.
|
Circulation
|
2009
|
1.10
|
|
18
|
Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke.
|
Atherosclerosis
|
2009
|
1.07
|
|
19
|
Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus.
|
Diab Vasc Dis Res
|
2010
|
1.05
|
|
20
|
Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas heart study.
|
Arterioscler Thromb Vasc Biol
|
2013
|
1.03
|
|
21
|
Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis.
|
Free Radic Biol Med
|
2009
|
1.01
|
|
22
|
Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study.
|
Clin Res Cardiol
|
2012
|
1.00
|
|
23
|
Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine.
|
J Am Coll Cardiol
|
2007
|
0.99
|
|
24
|
Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
|
Kidney Int
|
2009
|
0.98
|
|
25
|
P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease.
|
Br J Clin Pharmacol
|
2007
|
0.94
|
|
26
|
Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery.
|
Crit Care Med
|
2007
|
0.94
|
|
27
|
Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study.
|
Atherosclerosis
|
2008
|
0.94
|
|
28
|
Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine.
|
Am J Pathol
|
2010
|
0.93
|
|
29
|
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
|
Circulation
|
2011
|
0.93
|
|
30
|
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.
|
Nephrol Dial Transplant
|
2008
|
0.92
|
|
31
|
Telmisartan improves insulin sensitivity in nondiabetic patients with essential hypertension.
|
Metabolism
|
2006
|
0.92
|
|
32
|
Symmetric dimethylarginine is a marker of detrimental outcome in the acute phase after ischaemic stroke: role of renal function.
|
Clin Sci (Lond)
|
2012
|
0.92
|
|
33
|
Elevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality.
|
Clin Chem Lab Med
|
2005
|
0.90
|
|
34
|
Myeloperoxidase deficiency preserves vasomotor function in humans.
|
Eur Heart J
|
2011
|
0.90
|
|
35
|
Telmisartan improves endothelial function in patients with essential hypertension.
|
J Cardiovasc Pharmacol
|
2007
|
0.89
|
|
36
|
Stable isotope dilution assay for liquid chromatography-tandem mass spectrometric determination of L-homoarginine in human plasma.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2011
|
0.89
|
|
37
|
Association of multiple biomarkers and classical risk factors with early carotid atherosclerosis: results from the Gutenberg Health Study.
|
Clin Res Cardiol
|
2014
|
0.89
|
|
38
|
Divergence in urinary 8-iso-PGF(2alpha) (iPF(2alpha)-III, 15-F(2t)-IsoP) levels from gas chromatography-tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-PGF(2alpha). Possible methodological, mechanistic and clinical implications.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2003
|
0.88
|
|
39
|
Acute effects of various fast-food meals on vascular function and cardiovascular disease risk markers: the Hamburg Burger Trial.
|
Am J Clin Nutr
|
2007
|
0.88
|
|
40
|
A stable-isotope based technique for the determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2007
|
0.88
|
|
41
|
The L-Arginine-asymmetric dimethylarginine ratio is an independent predictor of mortality in dilated cardiomyopathy.
|
J Card Fail
|
2012
|
0.88
|
|
42
|
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies.
|
Circulation
|
2013
|
0.87
|
|
43
|
Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians.
|
Eur J Endocrinol
|
2009
|
0.87
|
|
44
|
Plasma concentrations of asymmetric dimethylarginine (ADMA) in metabolic syndrome.
|
Int J Cardiol
|
2007
|
0.87
|
|
45
|
Reference intervals for plasma L-arginine and the L-arginine:asymmetric dimethylarginine ratio in the Framingham Offspring Cohort.
|
J Nutr
|
2011
|
0.87
|
|
46
|
Mobilization of putative high-proliferative-potential endothelial colony-forming cells during antihypertensive treatment in patients with essential hypertension.
|
Stem Cells Dev
|
2007
|
0.87
|
|
47
|
Isoprostanes and neuroprostanes: total synthesis, biological activity and biomarkers of oxidative stress in humans.
|
Prostaglandins Other Lipid Mediat
|
2013
|
0.86
|
|
48
|
AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease.
|
Am J Physiol Renal Physiol
|
2012
|
0.86
|
|
49
|
AT1-receptor blockade with irbesartan improves peripheral but not coronary endothelial dysfunction in patients with stable coronary artery disease.
|
Atherosclerosis
|
2006
|
0.86
|
|
50
|
Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study.
|
Stroke
|
2009
|
0.86
|
|
51
|
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
|
Vasc Med
|
2005
|
0.85
|
|
52
|
A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria.
|
Cardiovasc Diabetol
|
2009
|
0.85
|
|
53
|
Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study.
|
Atherosclerosis
|
2009
|
0.85
|
|
54
|
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.
|
J Neurochem
|
2009
|
0.85
|
|
55
|
Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia.
|
Atherosclerosis
|
2006
|
0.85
|
|
56
|
Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania.
|
Clin Chem Lab Med
|
2014
|
0.85
|
|
57
|
Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke.
|
PLoS One
|
2009
|
0.84
|
|
58
|
The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia.
|
Gynecol Obstet Invest
|
2009
|
0.84
|
|
59
|
Asymmetrical dimethylarginine is increased in plasma and decreased in cerebrospinal fluid of patients with Alzheimer's disease.
|
Dement Geriatr Cogn Disord
|
2008
|
0.83
|
|
60
|
Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.
|
Circ Cardiovasc Genet
|
2014
|
0.83
|
|
61
|
L-homoarginine and cardiovascular disease.
|
Curr Opin Clin Nutr Metab Care
|
2015
|
0.83
|
|
62
|
Homoarginine--an independent marker of mortality in heart failure.
|
Int J Cardiol
|
2013
|
0.82
|
|
63
|
Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A2 receptor activation.
|
Br J Pharmacol
|
2014
|
0.82
|
|
64
|
Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia.
|
JAMA
|
2004
|
0.82
|
|
65
|
CLA does not impair endothelial function and decreases body weight as compared with safflower oil in overweight and obese male subjects.
|
J Am Coll Nutr
|
2011
|
0.81
|
|
66
|
Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.
|
J Alzheimers Dis
|
2012
|
0.81
|
|
67
|
Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry.
|
Nitric Oxide
|
2004
|
0.81
|
|
68
|
Rapid effect of single-dose rosiglitazone treatment on endothelial function in healthy men with normal glucose tolerance: data from a randomised, placebo-controlled, double-blind study.
|
Diab Vasc Dis Res
|
2010
|
0.81
|
|
69
|
Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans.
|
Amino Acids
|
2015
|
0.80
|
|
70
|
Increased symmetrical dimethylarginine in ischemic acute kidney injury as a causative factor of renal L-arginine deficiency.
|
Transl Res
|
2013
|
0.80
|
|
71
|
Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.
|
Clin Chem
|
2007
|
0.80
|
|
72
|
Impact of atorvastatin treatment on platelet-activating factor acetylhydrolase and 15-F(2trans)-isoprostane in hypercholesterolaemic patients.
|
Br J Clin Pharmacol
|
2007
|
0.80
|
|
73
|
Elevation of asymmetrical dimethylarginine (ADMA) and coronary artery disease in men with erectile dysfunction.
|
Eur Urol
|
2005
|
0.80
|
|
74
|
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
|
Diabetes Care
|
2013
|
0.79
|
|
75
|
Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serum.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2005
|
0.79
|
|
76
|
Plasma asymmetric dimethylarginine, L-arginine and left ventricular structure and function in a community-based sample.
|
Atherosclerosis
|
2008
|
0.79
|
|
77
|
Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism.
|
J Cardiovasc Pharmacol
|
2004
|
0.79
|
|
78
|
Polymorphisms in the promoter region of the dimethylarginine dimethylaminohydrolase 2 gene are associated with prevalence of hypertension.
|
Pharmacol Res
|
2009
|
0.78
|
|
79
|
L-Arginine enhances the triglyceride-lowering effect of simvastatin in patients with elevated plasma triglycerides.
|
Nutr Res
|
2009
|
0.78
|
|
80
|
Reference intervals of plasma homoarginine from the German Gutenberg Health Study.
|
Clin Chem Lab Med
|
2016
|
0.78
|
|
81
|
Accurate quantification of basal plasma levels of 3-nitrotyrosine and 3-nitrotyrosinoalbumin by gas chromatography-tandem mass spectrometry.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2003
|
0.77
|
|
82
|
Methodological considerations on the detection of 3-nitrotyrosine in the cardiovascular system.
|
Circ Res
|
2002
|
0.77
|
|
83
|
Determination of NG,NG-dimethyl-L-arginine, an endogenous NO synthase inhibitor, by gas chromatography-mass spectrometry.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2004
|
0.77
|
|
84
|
Homoarginine supplementation improves blood glucose in diet-induced obese mice.
|
Amino Acids
|
2015
|
0.77
|
|
85
|
Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension.
|
J Clin Pharmacol
|
2007
|
0.76
|
|
86
|
Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.
|
PLoS One
|
2012
|
0.75
|
|
87
|
FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.
|
J Heart Lung Transplant
|
2005
|
0.75
|
|
88
|
Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats.
|
Br J Nutr
|
2008
|
0.75
|
|
89
|
Unusual collision-induced dissociation of fluorated and non-fluorated alpha-nitrotoluene analogs in a gas chromatograph triple-stage quadrupole mass spectrometer under electron-capturing negative-ion chemical ionization conditions.
|
J Chromatogr A
|
2005
|
0.75
|
|
90
|
Measurement of homoarginine in human and mouse plasma by LC-MS/MS and ELISA: a comparison and a biological application.
|
Amino Acids
|
2015
|
0.75
|
|
91
|
Asymmetric dimethylarginine predicts outcome and time of stay in hospital in patients attending an internal medicine emergency room.
|
Clin Chim Acta
|
2008
|
0.75
|
|
92
|
FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies.
|
Transplantation
|
2004
|
0.75
|
|
93
|
Renal resistance index in renal allograft recipients: a role for ADMA.
|
Am J Kidney Dis
|
2009
|
0.75
|