Published in Circ Res on February 12, 2009
The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes. Nat Immunol (2011) 3.19
NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circ Res (2011) 2.38
Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ Res (2014) 1.78
MicroRNA-663 regulates human vascular smooth muscle cell phenotypic switch and vascular neointimal formation. Circ Res (2013) 1.67
NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology. Arterioscler Thromb Vasc Biol (2010) 1.53
Antithrombotic Effects of Nur77 and Nor1 Are Mediated Through Upregulating Thrombomodulin Expression in Endothelial Cells. Arterioscler Thromb Vasc Biol (2015) 1.42
MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1. Cardiovasc Res (2013) 1.21
Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines. J Neuroinflammation (2011) 0.95
Minocycline ameliorates LPS-induced inflammation in human monocytes by novel mechanisms including LOX-1, Nur77 and LITAF inhibition. Biochim Biophys Acta (2012) 0.93
Rapid temporal dynamics of transcription, protein synthesis, and secretion during macrophage activation. Mol Cell Proteomics (2014) 0.93
MCP-induced protein 1 suppresses TNFalpha-induced VCAM-1 expression in human endothelial cells. FEBS Lett (2010) 0.93
FHL2 protein is a novel co-repressor of nuclear receptor Nur77. J Biol Chem (2011) 0.90
Nuclear receptor 4A (NR4A) family - orphans no more. J Steroid Biochem Mol Biol (2015) 0.86
Nur77 deficiency leads to systemic inflammation in elderly mice. J Inflamm (Lond) (2015) 0.85
Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response to Beta-Adrenergic Stimulation. Mol Cell Biol (2015) 0.83
NR4A1 is associated with chronic low-grade inflammation in patients with type 2 diabetes. Exp Ther Med (2014) 0.82
Induction of Nur77 by hyperoside inhibits vascular smooth muscle cell proliferation and neointimal formation. Biochem Pharmacol (2014) 0.82
Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77. Arterioscler Thromb Vasc Biol (2012) 0.81
Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5. J Biol Chem (2014) 0.81
Molecular Interactions between NR4A Orphan Nuclear Receptors and NF-κB Are Required for Appropriate Inflammatory Responses and Immune Cell Homeostasis. Biomolecules (2015) 0.80
NR4A nuclear receptors in immunity and atherosclerosis. Curr Opin Lipidol (2013) 0.80
6-Mercaptopurine attenuates tumor necrosis factor-α production in microglia through Nur77-mediated transrepression and PI3K/Akt/mTOR signaling-mediated translational regulation. J Neuroinflammation (2016) 0.79
Nur77 suppresses pulmonary artery smooth muscle cell proliferation through inhibition of the STAT3/Pim-1/NFAT pathway. Am J Respir Cell Mol Biol (2014) 0.78
Orphan nuclear receptor Nur77 is a novel negative regulator of endothelin-1 expression in vascular endothelial cells. J Mol Cell Cardiol (2014) 0.78
Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages. PLoS One (2015) 0.78
NR4A1 promotes PDGF-BB-induced cell colony formation in soft agar. PLoS One (2014) 0.77
Nur77: orphaned at birth but adopted by the nuclear factor kappaB signaling pathway. Circ Res (2009) 0.77
Pim1 kinase promotes angiogenesis through phosphorylation of endothelial nitric oxide synthase at Ser-633. Cardiovasc Res (2015) 0.76
Nur77 attenuates endothelin-1 expression via downregulation of NF-κB and p38 MAPK in A549 cells and in an ARDS rat model. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Long-term effect of stents eluting 6-mercaptopurine in porcine coronary arteries. J Negat Results Biomed (2016) 0.75
SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death. Cell Death Differ (2017) 0.75
Orphan nuclear receptor Nur77 inhibits poly (I:C)-triggered acute liver inflammation by inducing the ubiquitin-editing enzyme A20. Oncotarget (2017) 0.75
5-Aminosalicylic Acid Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats by Increasing the Expression of Nur77. Inflammation (2017) 0.75
Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation (2002) 2.39
ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury. J Clin Invest (2008) 1.92
Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis. Mol Cell Biol (2003) 1.75
MicroRNA-663 regulates human vascular smooth muscle cell phenotypic switch and vascular neointimal formation. Circ Res (2013) 1.67
FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1. Circ Res (2006) 1.63
cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesol. Antimicrob Agents Chemother (2005) 1.48
C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection. Immunity (2013) 1.46
Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia. Proc Natl Acad Sci U S A (2009) 1.43
11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression. Bioorg Med Chem Lett (2003) 1.38
Flower numbers, pod production, pollen viability, and pistil function are reduced and flower and pod abortion increased in chickpea (Cicer arietinum L.) under terminal drought. J Exp Bot (2009) 1.24
Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1. Circ Res (2008) 1.24
MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1. Cardiovasc Res (2013) 1.21
Cap1p is involved in multiple pathways of oxidative stress response in Candida albicans. Free Radic Biol Med (2005) 1.21
1alpha,25-dihydroxyvitamin D3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase. Circ Res (2002) 1.20
Production of viable male unreduced gametes in Brassica interspecific hybrids is genotype specific and stimulated by cold temperatures. BMC Plant Biol (2011) 1.12
Microspore culture preferentially selects unreduced (2n) gametes from an interspecific hybrid of Brassica napus L. x Brassica carinata Braun. Theor Appl Genet (2009) 1.11
Transcriptome analysis of the salivary glands of Dermacentor andersoni Stiles (Acari: Ixodidae). Insect Biochem Mol Biol (2006) 1.11
MicroRNA-145 protects cardiomyocytes against hydrogen peroxide (H₂O₂)-induced apoptosis through targeting the mitochondria apoptotic pathway. PLoS One (2012) 1.08
Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole. Antimicrob Agents Chemother (2006) 1.08
Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids. Cardiovasc Res (2008) 1.07
Proteomic analysis reveals a synergistic mechanism of fluconazole and berberine against fluconazole-resistant Candida albicans: endogenous ROS augmentation. J Proteome Res (2009) 1.07
Antifungal activities and action mechanisms of compounds from Tribulus terrestris L. J Ethnopharmacol (2005) 1.06
Genome structure affects the rate of autosyndesis and allosyndesis in AABC, BBAC and CCAB Brassica interspecific hybrids. Chromosome Res (2010) 1.06
Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling. Proc Natl Acad Sci U S A (2012) 1.04
Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells. Eur J Pharm Sci (2005) 1.03
Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells. Cancer Res (2008) 1.01
Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1. Biochem J (2009) 0.99
Genotypic effects on the frequency of homoeologous and homologous recombination in Brassica napus × B. carinata hybrids. Theor Appl Genet (2010) 0.98
Lipotoxicity in HepG2 cells triggered by free fatty acids. Am J Transl Res (2011) 0.96
Using Galleria mellonella-Candida albicans infection model to evaluate antifungal agents. Biol Pharm Bull (2013) 0.94
Fluconazole assists berberine to kill fluconazole-resistant Candida albicans. Antimicrob Agents Chemother (2013) 0.93
Quantification of magnetic susceptibility in several strains of Bacillus spores: implications for separation and detection. Biotechnol Bioeng (2007) 0.92
RTA2, a novel gene involved in azole resistance in Candida albicans. Biochem Biophys Res Commun (2008) 0.92
MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA. PLoS One (2013) 0.91
Tumor necrosis factor-alpha mediates polymethylmethacrylate particle-induced NF-kappaB activation in osteoclast precursor cells. J Orthop Res (2002) 0.90
miR-145 inhibits isoproterenol-induced cardiomyocyte hypertrophy by targeting the expression and localization of GATA6. FEBS Lett (2013) 0.90
MicroRNA-133b stimulates ovarian estradiol synthesis by targeting Foxl2. FEBS Lett (2013) 0.89
The orphan nuclear receptor Nur77 regulates decidual prolactin expression in human endometrial stromal cells. Biochem Biophys Res Commun (2010) 0.89
Sequencing consolidates molecular markers with plant breeding practice. Theor Appl Genet (2015) 0.89
In vitro and in vivo activities of pterostilbene against Candida albicans biofilms. Antimicrob Agents Chemother (2014) 0.88
FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1. Arterioscler Thromb Vasc Biol (2009) 0.88
Comparative analysis of genetic diversity between Qinghai-Tibetan wild and Chinese landrace barley. Genome (2009) 0.88
Allelic variations of a light harvesting chlorophyll a/b-binding protein gene (Lhcb1) associated with agronomic traits in barley. PLoS One (2012) 0.88
Proteomic analysis reveals a metabolism shift in a laboratory fluconazole-resistant Candida albicans strain. J Proteome Res (2007) 0.87
Discovery of novel Bmy1 alleles increasing β-amylase activity in Chinese landraces and Tibetan wild barley for improvement of malting quality via MAS. PLoS One (2013) 0.87
Synthesis of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase (CYP51). Eur J Med Chem (2007) 0.86
Fcr1p inhibits development of fluconazole resistance in Candida albicans by abolishing CDR1 induction. Biol Pharm Bull (2007) 0.86
Tissue- and stage-specific expression of two lipophorin receptor variants with seven and eight ligand-binding repeats in the adult mosquito. J Biol Chem (2003) 0.86
Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats. J Hypertens (2005) 0.86
In vitro and in vivo antifungal activities of the eight steroid saponins from Tribulus terrestris L. with potent activity against fluconazole-resistant fungal pathogens. Biol Pharm Bull (2005) 0.86
-216G/T (rs712829), a functional variant of the EGFR promoter, is associated with the pleural metastasis of lung adenocarcinoma. Oncol Lett (2013) 0.85
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs. Eur J Pharmacol (2006) 0.85
Krüppel-like factor 12 negatively regulates human endometrial stromal cell decidualization. Biochem Biophys Res Commun (2013) 0.85
cDNA microarray analysis of differential gene expression and regulation in clinically drug-resistant isolates of Candida albicans from bone marrow transplanted patients. Int J Med Microbiol (2006) 0.85
HOXA10 suppresses p/CAF promoter activity via three consecutive TTAT units in human endometrial stromal cells. Biochem Biophys Res Commun (2008) 0.84
Protective effects of Nicotiflorin on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats. Pharmacol Biochem Behav (2007) 0.84
Effect of tetrandrine against Candida albicans biofilms. PLoS One (2013) 0.84
Orphan nuclear receptor Nur77 regulates androgen receptor gene expression in mouse ovary. PLoS One (2012) 0.83
CaIPF7817 is involved in the regulation of redox homeostasis in Candida albicans. Biochem Biophys Res Commun (2007) 0.83
Calcium-activated-calcineurin reduces the In vitro and In vivo sensitivity of fluconazole to Candida albicans via Rta2p. PLoS One (2012) 0.83
Incomplete endothelialization and late dislocation after implantation of an Amplatzer septal occluder device. Circulation (2011) 0.82
Effects of Changtai granules, a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. World J Gastroenterol (2005) 0.82
Lymphtoxin beta receptor-Ig protects from T-cell-mediated liver injury in mice through blocking LIGHT/HVEM signaling. Biol Pharm Bull (2006) 0.82
MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1. PLoS One (2013) 0.81
Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77. Arterioscler Thromb Vasc Biol (2012) 0.81
GmPAP4, a novel purple acid phosphatase gene isolated from soybean (Glycine max), enhanced extracellular phytate utilization in Arabidopsis thaliana. Plant Cell Rep (2014) 0.81
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity. Reprod Biol Endocrinol (2013) 0.81
Activation of sphingosine kinase-1 mediates inhibition of vascular smooth muscle cell apoptosis by hyperglycemia. Diabetes (2007) 0.81
ECM17-dependent methionine/cysteine biosynthesis contributes to biofilm formation in Candida albicans. Fungal Genet Biol (2012) 0.81
Ascorbic acid decreases the antifungal effect of fluconazole in the treatment of candidiasis. Clin Exp Pharmacol Physiol (2009) 0.80
Baicalein induces programmed cell death in Candida albicans. J Microbiol Biotechnol (2009) 0.80
Treatment of a Bennett fracture using tension band wiring. J Hand Surg Am (2012) 0.80
Effect of esculentoside A on autoimmunity in mice and its possible mechanisms. Acta Pharmacol Sin (2002) 0.80
Lymphtoxin beta receptor-Ig ameliorates TNBS-induced colitis via blocking LIGHT/HVEM signaling. Pharmacol Res (2005) 0.80
High-frequency genetic contents variations in clinical Candida albicans isolates. Biol Pharm Bull (2011) 0.80
Effects of esculentoside A on production of interleukin-1, 2, and prostaglandin E2. Acta Pharmacol Sin (2004) 0.80
Asynchronism of the recovery of baroreflex sensitivity, blood pressure, and consciousness from anesthesia in rats. J Cardiovasc Pharmacol (2004) 0.80
Single nucleotide polymorphisms in HSP17.8 and their association with agronomic traits in barley. PLoS One (2013) 0.80
Lattice defects and thermoelectric properties: the case of p-type CuInTe2 chalcopyrite on introduction of zinc. Dalton Trans (2014) 0.79
Acetyl-coenzyme A synthetase 2 is a nuclear protein required for replicative longevity in Saccharomyces cerevisiae. Mol Cell Biochem (2009) 0.79
Femoral venous hemostasis in children using the technique of "figure-of-eight" sutures. Congenit Heart Dis (2013) 0.79
Differential recovery of lupin proteins from the gluten matrix in lupin-wheat bread as revealed by mass spectrometry and two-dimensional electrophoresis. J Agric Food Chem (2011) 0.78
Cyto-evolution of Boronia genomes revealed by fluorescent in situ hybridization with rDNA probes. Genome (2003) 0.78
Nur77 suppresses pulmonary artery smooth muscle cell proliferation through inhibition of the STAT3/Pim-1/NFAT pathway. Am J Respir Cell Mol Biol (2014) 0.78
Importance of spatial and spectral data reduction in the detection of internal defects in food products. Appl Spectrosc (2015) 0.78
Occurrence and clinical significance of in-hospital acquired thrombocytopenia in patients undergoing transcatheter device closure for congenital heart defect. Thromb Res (2012) 0.78
cDNA array analysis of the differential expression change in virulence-related genes during the development of resistance in Candida albicans. Acta Biochim Biophys Sin (Shanghai) (2005) 0.78
Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis. PLoS One (2013) 0.78
CYR61 modulates the vascular endothelial growth factor C expression of decidual NK cells via PI3K/AKT pathway. Am J Reprod Immunol (2011) 0.78
Proteomic analysis of Rta2p-dependent raft-association of detergent-resistant membranes in Candida albicans. PLoS One (2012) 0.78
Gene Expression Profiling of H9c2 Cells Subjected to H2O2-Induced Apoptosis with/without AF-HF001. Biol Pharm Bull (2015) 0.77