Michael S Lawrence

Author PubWeight™ 262.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The landscape of somatic copy-number alteration across human cancers. Nature 2010 31.88
2 Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008 30.02
3 Initial genome sequencing and analysis of multiple myeloma. Nature 2011 17.28
4 The mutational landscape of head and neck squamous cell carcinoma. Science 2011 16.88
5 Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat Biotechnol 2013 16.13
6 The genomic complexity of primary human prostate cancer. Nature 2011 14.06
7 A landscape of driver mutations in melanoma. Cell 2012 12.61
8 Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012 11.69
9 SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011 11.07
10 Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet 2012 9.93
11 Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell 2013 9.24
12 Melanoma genome sequencing reveals frequent PREX2 mutations. Nature 2012 7.77
13 Sequence analysis of mutations and translocations across breast cancer subtypes. Nature 2012 7.76
14 Pan-cancer patterns of somatic copy number alteration. Nat Genet 2013 7.73
15 Punctuated evolution of prostate cancer genomes. Cell 2013 7.23
16 Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci U S A 2012 7.14
17 Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med 2015 5.71
18 Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature 2012 5.23
19 Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov 2011 4.80
20 The genetic landscape of high-risk neuroblastoma. Nat Genet 2013 4.71
21 An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat Genet 2013 4.69
22 Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat Genet 2013 4.48
23 Comprehensive identification of mutational cancer driver genes across 12 tumor types. Sci Rep 2013 3.92
24 Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. Proc Natl Acad Sci U S A 2012 3.06
25 A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J Clin Invest 2012 2.42
26 Experimental discovery of sRNAs in Vibrio cholerae by direct cloning, 5S/tRNA depletion and parallel sequencing. Nucleic Acids Res 2009 2.25
27 Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. Genome Res 2012 1.82
28 Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. Nat Genet 2013 1.56
29 Oncotator: cancer variant annotation tool. Hum Mutat 2015 1.52
30 Paired-end sequencing of Fosmid libraries by Illumina. Genome Res 2012 1.52
31 Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes. Nat Biotechnol 2015 1.47
32 Identification of driver genes in hepatocellular carcinoma by exome sequencing. Hepatology 2013 1.41
33 Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. J Clin Oncol 2013 1.40
34 Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proc Natl Acad Sci U S A 2013 1.33
35 Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep 2016 0.96
36 Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun 2014 0.84
37 Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab. Mol Cancer 2014 0.80