Published in Neuropharmacology on February 21, 2009
Review of pathological hallmarks of schizophrenia: comparison of genetic models with patients and nongenetic models. Schizophr Bull (2009) 1.44
Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia. Neuropsychopharmacology (2011) 1.42
Delayed procedural learning in α7-nicotinic acetylcholine receptor knockout mice. Genes Brain Behav (2011) 1.08
Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. Neuropsychopharmacology (2011) 1.01
α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease. Open Med Chem J (2010) 1.00
Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test. Behav Brain Res (2012) 0.97
Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology (2011) 0.95
Axonal α7 nicotinic ACh receptors modulate presynaptic NMDA receptor expression and structural plasticity of glutamatergic presynaptic boutons. Proc Natl Acad Sci U S A (2010) 0.93
Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist. Neuropsychopharmacology (2012) 0.89
Complex relationships of nicotinic receptor actions and cognitive functions. Biochem Pharmacol (2013) 0.88
Failure of NMDA receptor hypofunction to induce a pathological reduction in PV-positive GABAergic cell markers. Neurosci Lett (2010) 0.87
Social interaction and social withdrawal in rodents as readouts for investigating the negative symptoms of schizophrenia. Eur Neuropsychopharmacol (2013) 0.82
Improvement of attentional function with antagonism of nicotinic receptors in female rats. Eur J Pharmacol (2013) 0.82
Hippocampal infusions of MARCKS peptides impair memory of rats on the radial-arm maze. Brain Res (2009) 0.81
Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1. Psychopharmacology (Berl) (2013) 0.79
Effects of an alpha7 nicotinic receptor agonist and stress on spatial memory in an animal model of Alzheimer's disease. Biomed Res Int (2013) 0.79
α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties. PLoS One (2015) 0.78
Chronic phencyclidine increases synapsin-1 and synaptic adaptation proteins in the medial prefrontal cortex. ISRN Psychiatry (2013) 0.77
Severe cross-modal object recognition deficits in rats treated sub-chronically with NMDA receptor antagonists are reversed by systemic nicotine: implications for abnormal multisensory integration in schizophrenia. Neuropsychopharmacology (2012) 0.76
The alpha-7 nicotinic receptor partial agonist/5-HT3 antagonist RG3487 enhances cortical and hippocampal dopamine and acetylcholine release. Psychopharmacology (Berl) (2013) 0.76
An experimental study on (131)I-CHIBA-1001: a radioligand for α7 nicotinic acetylcholine receptors. PLoS One (2013) 0.76
Ethanol and phencyclidine interact with respect to nucleus accumbens dopamine release: differential effects of administration order and pretreatment protocol. Front Behav Neurosci (2010) 0.76
Theranostic Biomarkers for Schizophrenia. Int J Mol Sci (2017) 0.75
Comparative effects of sertraline, haloperidol or olanzapine treatments on ketamine-induced changes in mouse behaviours. Metab Brain Dis (2017) 0.75
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nat Neurosci (2008) 4.04
RFamide-related peptide gene is a melatonin-driven photoperiodic gene. Endocrinology (2007) 1.89
The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y. Neurosci Biobehav Rev (2002) 1.41
NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growth. Proc Natl Acad Sci U S A (2005) 1.30
Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain. Neuropharmacology (2005) 1.28
Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology. Curr Pharm Des (2010) 1.27
Kisspeptin mediates the photoperiodic control of reproduction in hamsters. Curr Biol (2006) 1.23
Erythropoietin protects the developing brain against N-methyl-D-aspartate receptor antagonist neurotoxicity. Neurobiol Dis (2004) 1.23
Oxytocin--anatomy and functional assignments: a minireview. Endocr Regul (2005) 1.21
Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system. Endocrinology (2011) 1.08
The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia. J Neuroimmunol (2012) 1.08
Circadian control of kisspeptin and a gated GnRH response mediate the preovulatory luteinizing hormone surge. Endocrinology (2010) 1.06
K(v)7 channels: function, pharmacology and channel modulators. Curr Top Med Chem (2006) 1.05
Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS. J Physiol (2008) 1.03
Kisspeptins: bridging energy homeostasis and reproduction. Brain Res (2010) 1.02
Kisspeptin and the seasonal control of reproduction in hamsters. Peptides (2008) 1.02
The imprinted gene neuronatin is regulated by metabolic status and associated with obesity. Obesity (Silver Spring) (2009) 1.02
The KCNQ channel opener retigabine inhibits the activity of mesencephalic dopaminergic systems of the rat. J Pharmacol Exp Ther (2006) 1.02
The neuronal KCNQ channel opener retigabine inhibits locomotor activity and reduces forebrain excitatory responses to the psychostimulants cocaine, methylphenidate and phencyclidine. Eur J Pharmacol (2007) 1.00
Cognitive deficits in the rat chronic mild stress model for depression: relation to anhedonic-like responses. Behav Brain Res (2008) 1.00
Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment. J Psychiatr Res (2010) 1.00
Stimulatory effect of RFRP-3 on the gonadotrophic axis in the male Syrian hamster: the exception proves the rule. Endocrinology (2012) 0.99
Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants. Eur J Pharmacol (2007) 0.98
Melatonin regulates type 2 deiodinase gene expression in the Syrian hamster. Endocrinology (2006) 0.97
Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease. Synapse (2002) 0.96
Kisspeptin: a key link to seasonal breeding. Rev Endocr Metab Disord (2007) 0.95
Maturation of kisspeptinergic neurons coincides with puberty onset in male rats. Peptides (2009) 0.95
Expression of brain derived neurotrophic factor, activity-regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine. Eur J Pharmacol (2006) 0.93
Putative neuroprotective actions of N-acyl-ethanolamines. Pharmacol Ther (2002) 0.92
11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements. J Nucl Med (2011) 0.89
Antidepressant-like effects of nicotine and mecamylamine in the mouse forced swim and tail suspension tests: role of strain, test and sex. Behav Pharmacol (2009) 0.89
Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist. Neuropsychopharmacology (2012) 0.89
Nicotine, but not mecamylamine, enhances antidepressant-like effects of citalopram and reboxetine in the mouse forced swim and tail suspension tests. Behav Brain Res (2008) 0.87
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior. J Med Chem (2009) 0.87
The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets? Curr Drug Targets (2012) 0.86
Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats. PLoS One (2011) 0.86
Microduplication of 15q13.3 and Xq21.31 in a family with Tourette syndrome and comorbidities. Am J Med Genet B Neuropsychiatr Genet (2013) 0.86
Kv 7 positive modulators reduce detrusor overactivity and increase bladder capacity in rats. Basic Clin Pharmacol Toxicol (2011) 0.86
Antibodies in narcolepsy-cataplexy patient serum bind to rat hypocretin neurons. Neuroreport (2007) 0.85
Lu 28-179 labels a sigma(2)-site in rat and human brain. Neuropharmacology (2002) 0.85
Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice. Neurobiol Aging (2010) 0.85
Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus). Horm Behav (2013) 0.84
Melatonin controls seasonal breeding by a network of hypothalamic targets. Neuroendocrinology (2009) 0.84
Repeated administration of alpha7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases alpha7 nAChR levels in the brain. J Neurochem (2010) 0.84
Neuropathological and biochemical features of traumatic injury in the developing brain. Neurotox Res (2003) 0.84
Differential regulation of c-Fos and FosB in the rat brain after amygdala kindling. Cell Mol Neurobiol (2006) 0.83
CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate. Front Pharmacol (2012) 0.83
Distinct neural pathways mediate α7 nicotinic acetylcholine receptor-dependent activation of the forebrain. Cereb Cortex (2010) 0.83
Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice. Peptides (2013) 0.83
Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated. Brain Struct Funct (2013) 0.83
Projections from the raphe nuclei to the suprachiasmatic nucleus of the rat. J Chem Neuroanat (2003) 0.82
Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat. Brain Res Bull (2012) 0.82
Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test. J Psychopharmacol (2010) 0.82
Afferent projections to the hamster intergeniculate leaflet demonstrated by retrograde and anterograde tracing. Brain Res Bull (2003) 0.82
BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Hum Brain Mapp (2014) 0.81
Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia. J Neurosci Res (2013) 0.81
Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neurosci Lett (2013) 0.81
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies. J Med Chem (2014) 0.81
Opposite effect of phencyclidine on activity-regulated cytoskeleton-associated protein (Arc) in juvenile and adult limbic rat brain regions. Neurochem Int (2009) 0.81
Type I and II positive allosteric modulators differentially modulate agonist-induced up-regulation of α7 nicotinic acetylcholine receptors. J Neurochem (2012) 0.81
Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus after sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats. Endocrinology (2014) 0.81
Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: an effect similar to antipsychotics. J Neurosci Res (2007) 0.80
Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: a comparison of SSR180711 and PNU-282987. Pharmacol Biochem Behav (2011) 0.80
Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice. J Alzheimers Dis (2010) 0.80
Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder. Bipolar Disord (2011) 0.80
The novel triple monoamine reuptake inhibitor tesofensine induces sustained weight loss and improves glycemic control in the diet-induced obese rat: comparison to sibutramine and rimonabant. Eur J Pharmacol (2010) 0.80
GABA(A) receptor α subunits differentially contribute to diazepam tolerance after chronic treatment. PLoS One (2012) 0.80
Normal hypothalamo-pituitary-adrenal axis function in a rat model of peripheral neuropathic pain. Brain Res (2005) 0.80
Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats. Reprod Biol (2013) 0.80
The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus. Neurotoxicology (2013) 0.79
K(v) 7 (KCNQ) channel openers normalize central 2-deoxyglucose uptake in a mouse model of mania and increase prefrontal cortical and hippocampal serine-9 phosphorylation levels of GSK3β. J Neurochem (2012) 0.79
Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass. Obesity (Silver Spring) (2012) 0.79
Tesofensine, a novel triple monoamine reuptake inhibitor, induces appetite suppression by indirect stimulation of alpha1 adrenoceptor and dopamine D1 receptor pathways in the diet-induced obese rat. Neuropsychopharmacology (2010) 0.79
Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APP(swe)/PS1ΔE9 mice. Neurosci Lett (2010) 0.79
Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy. Neurosci Lett (2013) 0.79
Use of biomarkers in the discovery of novel anti-schizophrenia drugs. Drug Discov Today (2009) 0.79
The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42. Brain Res (2008) 0.79
GABA regulates the rat hypothalamic-pituitary-adrenocortical axis via different GABA-A receptor alpha-subtypes. Ann N Y Acad Sci (2008) 0.79
Hypertonic saline and immobilization induce Fos expression in mouse brain catecholaminergic cell groups: colocalization with tyrosine hydroxylase and neuropeptide Y. Ann N Y Acad Sci (2004) 0.78
The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat. Neurosci Lett (2007) 0.78
Fos expression in hypocretinergic neurons in C57B1/6 male and female mice after long-term consumption of high fat diet. Endocr Regul (2008) 0.78
Acute phencyclidine treatment induces extensive and distinct protein phosphorylation in rat frontal cortex. J Proteome Res (2014) 0.77
The pharmacological effect of positive KCNQ (Kv7) modulators on dopamine release from striatal slices. Basic Clin Pharmacol Toxicol (2011) 0.77
RO4938581, a GABAAα5 modulator, displays strong CYP1A2 autoinduction properties in rats. Biochem Pharmacol (2013) 0.77
Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats. Cell Mol Neurobiol (2008) 0.77
Chronic oral nicotine increases brain [3H]epibatidine binding and responsiveness to antidepressant drugs, but not nicotine, in the mouse forced swim test. Psychopharmacology (Berl) (2009) 0.77
Activation of FOS in hypocretin neurons of the rat by insulin-induced hypoglycemia. Endocr Regul (2004) 0.77
A combined α7 nicotinic acetylcholine receptor agonist and monoamine reuptake inhibitor, NS9775, represents a novel profile with potential benefits in emotional and cognitive disturbances. Neuropharmacology (2013) 0.77
Anti-hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats. Obesity (Silver Spring) (2013) 0.76