Functional maturation of the exocytotic machinery at gerbil hair cell ribbon synapses.

PubWeight™: 1.07‹?› | Rank: Top 10%

🔗 View Article (PMC 2683959)

Published in J Physiol on February 23, 2009

Authors

Stuart L Johnson1, Christoph Franz, Marlies Knipper, Walter Marcotti

Author Affiliations

1: Department of Biomedical Science, University of Sheffield, Sheffield S10 2TN, UK.

Articles citing this

The diverse roles of ribbon synapses in sensory neurotransmission. Nat Rev Neurosci (2010) 1.83

Elementary properties of CaV1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells. J Physiol (2009) 1.35

Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells. Nat Neurosci (2011) 1.33

miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells. Proc Natl Acad Sci U S A (2011) 1.32

Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses. Nat Neurosci (2009) 1.24

Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells. PLoS Biol (2011) 1.13

Single Ca2+ channels and exocytosis at sensory synapses. J Physiol (2013) 0.99

Synaptic transfer from outer hair cells to type II afferent fibers in the rat cochlea. J Neurosci (2012) 0.94

Functional assembly of mammalian cochlear hair cells. Exp Physiol (2011) 0.90

Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells. J Neurosci (2013) 0.89

Development of K(+) and Na(+) conductances in rodent postnatal semicircular canal type I hair cells. Am J Physiol Regul Integr Comp Physiol (2009) 0.83

Summing Across Different Active Zones can Explain the Quasi-Linear Ca-Dependencies of Exocytosis by Receptor Cells. Front Synaptic Neurosci (2010) 0.83

Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications. Cell Commun Signal (2012) 0.82

Quantitative analysis of ribbons, vesicles, and cisterns at the cat inner hair cell synapse: correlations with spontaneous rate. J Comp Neurol (2013) 0.82

Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses. Open Biol (2013) 0.82

Auditory function in the Tc1 mouse model of down syndrome suggests a limited region of human chromosome 21 involved in otitis media. PLoS One (2012) 0.80

Synaptic studies inform the functional diversity of cochlear afferents. Hear Res (2015) 0.79

Exocytosis in the frog amphibian papilla. J Assoc Res Otolaryngol (2011) 0.79

Elementary properties of Ca(2+) channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses. Front Cell Neurosci (2015) 0.78

Developmental acquisition of a rapid calcium-regulated vesicle supply allows sustained high rates of exocytosis in auditory hair cells. PLoS One (2011) 0.78

Modeling the influence of short term depression in vesicle release and stochastic calcium channel gating on auditory nerve spontaneous firing statistics. Front Comput Neurosci (2014) 0.76

Spatial Gradients in the Size of Inner Hair Cell Ribbons Emerge Before the Onset of Hearing in Rats. J Assoc Res Otolaryngol (2017) 0.75

The Coupling between Ca(2+) Channels and the Exocytotic Ca(2+) Sensor at Hair Cell Ribbon Synapses Varies Tonotopically along the Mature Cochlea. J Neurosci (2017) 0.75

Enlargement of ribbons in zebrafish hair cells increases calcium currents, but disrupts afferent spontaneous activity and timing of stimulus onset. J Neurosci (2017) 0.75

Articles cited by this

The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol (2000) 19.46

A cochlear frequency-position function for several species--29 years later. J Acoust Soc Am (1990) 8.56

Membrane fusion. Cell (2003) 7.68

Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release. Neuron (1998) 5.96

Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels. Cell (2000) 5.08

Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells. J Neurosci (1990) 4.62

The active cochlea. J Neurosci (1992) 4.37

Transmitter release at the hair cell ribbon synapse. Nat Neurosci (2002) 4.08

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell (2006) 3.71

Hair cell synaptic ribbons are essential for synchronous auditory signalling. Nature (2005) 3.54

Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel. J Neurosci (1997) 3.28

RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon function. Neuron (2000) 3.21

Kinetics of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse of the mouse. Proc Natl Acad Sci U S A (2000) 3.07

Expression of a potassium current in inner hair cells during development of hearing in mice. Nature (1998) 2.91

Few CaV1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse. J Neurosci (2005) 2.85

Calcium entry and transmitter release at voltage-clamped nerve terminals of squid. J Physiol (1985) 2.62

Structure and function of ribbon synapses. Trends Neurosci (2005) 2.45

Intracellular studies of hair cells in the mammalian cochlea. J Physiol (1978) 2.32

Calcium-triggered exocytosis and endocytosis in an isolated presynaptic cell: capacitance measurements in saccular hair cells. Neuron (1994) 2.29

Evidence that vesicles on the synaptic ribbon of retinal bipolar neurons can be rapidly released. Neuron (1996) 2.18

CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells. J Neurosci (2003) 2.12

Time course and calcium dependence of transmitter release at a single ribbon synapse. Proc Natl Acad Sci U S A (2007) 2.11

Synaptic vesicle populations in saccular hair cells reconstructed by electron tomography. J Neurosci (1999) 2.05

The presynaptic function of mouse cochlear inner hair cells during development of hearing. J Neurosci (2001) 1.99

The cochlear place-frequency map of the adult and developing Mongolian gerbil. Hear Res (1996) 1.97

Confocal imaging of calcium microdomains and calcium extrusion in turtle hair cells. Neuron (1995) 1.91

Developmental expression of the potassium current IK,n contributes to maturation of mouse outer hair cells. J Physiol (1999) 1.90

Response characteristics of mammalian cochlear hair cells. J Neurosci (1985) 1.89

Synaptic ribbon enables temporal precision of hair cell afferent synapse by increasing the number of readily releasable vesicles: a modeling study. J Neurophysiol (2008) 1.83

Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells. J Physiol (2004) 1.82

Sodium and calcium currents shape action potentials in immature mouse inner hair cells. J Physiol (2003) 1.75

Fast vesicle replenishment allows indefatigable signalling at the first auditory synapse. Nature (2005) 1.67

Time and intensity coding at the hair cell's ribbon synapse. J Physiol (2005) 1.57

Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses. J Neurosci (2008) 1.53

Coding of neuronal differentiation by calcium transients. Bioessays (2000) 1.48

Ribbon synapses in the developing intact and cultured organ of Corti in the mouse. J Neurosci (1982) 1.47

Calcium- and otoferlin-dependent exocytosis by immature outer hair cells. J Neurosci (2008) 1.46

Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse. J Physiol (2006) 1.46

Biophysical properties of CaV1.3 calcium channels in gerbil inner hair cells. J Physiol (2008) 1.34

Cav1.3 (alpha1D) Ca2+ currents in neonatal outer hair cells of mice. J Physiol (2003) 1.29

Genetic deletion of SK2 channels in mouse inner hair cells prevents the developmental linearization in the Ca2+ dependence of exocytosis. J Physiol (2007) 1.22

Hair cell afferent synapses. Curr Opin Neurobiol (2008) 1.22

Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat. Eur J Neurosci (2006) 1.21

Age-related changes in the C57BL/6J mouse cochlea. II. Ultrastructural findings. Brain Res (1981) 1.17

Sodium current expression during postnatal development of rat outer hair cells. Pflugers Arch (1997) 1.13

Ontogeny of neural discharge patterns in the ventral cochlear nucleus of the mongolian gerbil. Brain Res (1985) 0.89

Articles by these authors

Prestin-driven cochlear amplification is not limited by the outer hair cell membrane time constant. Neuron (2011) 2.72

Beethoven, a mouse model for dominant, progressive hearing loss DFNA36. Nat Genet (2002) 2.31

Development and properties of stereociliary link types in hair cells of the mouse cochlea. J Comp Neurol (2005) 2.15

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1. Hum Mol Genet (2006) 1.94

Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells. Dev Biol (2005) 1.84

Restoration of auditory evoked responses by human ES-cell-derived otic progenitors. Nature (2012) 1.83

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy. Brain (2007) 1.82

Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells. J Physiol (2004) 1.82

Protein kinase CK2 is coassembled with small conductance Ca(2+)-activated K+ channels and regulates channel gating. Neuron (2004) 1.77

Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci U S A (2004) 1.67

Functional significance of channels and transporters expressed in the inner ear and kidney. Am J Physiol Cell Physiol (2007) 1.57

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2. Hum Mol Genet (2005) 1.54

Developmental regulation of nicotinic synapses on cochlear inner hair cells. J Neurosci (2004) 1.54

Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses. J Neurosci (2008) 1.53

Resting potential and submembrane calcium concentration of inner hair cells in the isolated mouse cochlea are set by KCNQ-type potassium channels. J Neurosci (2003) 1.44

Thyroid hormone deficiency affects postnatal spiking activity and expression of Ca2+ and K+ channels in rodent inner hair cells. J Neurosci (2007) 1.39

Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells. PLoS One (2011) 1.38

Elementary properties of CaV1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells. J Physiol (2009) 1.35

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. J Neurosci (2007) 1.34

Biophysical properties of CaV1.3 calcium channels in gerbil inner hair cells. J Physiol (2008) 1.34

Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells. Nat Neurosci (2011) 1.33

Persistence of Ca(v)1.3 Ca2+ channels in mature outer hair cells supports outer hair cell afferent signaling. J Neurosci (2007) 1.33

miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells. Proc Natl Acad Sci U S A (2011) 1.32

TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice. J Physiol (2008) 1.30

Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses. Nat Neurosci (2009) 1.24

Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss. Development (2003) 1.22

Genetic deletion of SK2 channels in mouse inner hair cells prevents the developmental linearization in the Ca2+ dependence of exocytosis. J Physiol (2007) 1.22

Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin. Proc Natl Acad Sci U S A (2002) 1.22

A behavioral paradigm to judge acute sodium salicylate-induced sound experience in rats: a new approach for an animal model on tinnitus. Hear Res (2003) 1.22

Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat. Eur J Neurosci (2006) 1.21

Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell. Hum Mol Genet (2009) 1.21

Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons. Genes Dev (2002) 1.20

Expression of prestin-homologous solute carrier (SLC26) in auditory organs of nonmammalian vertebrates and insects. Proc Natl Acad Sci U S A (2003) 1.17

Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells. PLoS Biol (2011) 1.13

Channel gating forces govern accuracy of mechano-electrical transduction in hair cells. Proc Natl Acad Sci U S A (2003) 1.12

Voltage-sensitive prestin orthologue expressed in zebrafish hair cells. J Physiol (2007) 1.10

Thyroid hormone receptors TRalpha1 and TRbeta differentially regulate gene expression of Kcnq4 and prestin during final differentiation of outer hair cells. J Cell Sci (2006) 1.06

Ca(v)1.3 and BK channels for timing and regulating cell firing. Mol Neurobiol (2010) 1.06

Noise-induced inner hair cell ribbon loss disturbs central arc mobilization: a novel molecular paradigm for understanding tinnitus. Mol Neurobiol (2012) 1.04

The resting transducer current drives spontaneous activity in prehearing mammalian cochlear inner hair cells. J Neurosci (2012) 1.04

The reduced cochlear output and the failure to adapt the central auditory response causes tinnitus in noise exposed rats. PLoS One (2013) 1.02

Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule. Mol Cell Neurosci (2010) 1.01

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. Proc Natl Acad Sci U S A (2013) 0.99

cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. Nat Med (2012) 0.99

Burst activity and ultrafast activation kinetics of CaV1.3 Ca²⁺ channels support presynaptic activity in adult gerbil hair cell ribbon synapses. J Physiol (2013) 0.96

Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity. Proc Natl Acad Sci U S A (2013) 0.95

Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss. J Neurosci (2012) 0.93

Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells. Stem Cells (2009) 0.92

A novel vestibular approach for gene transfer into the inner ear. Audiol Neurootol (2002) 0.91

Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies. J Biol Chem (2012) 0.91

Midazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression: implications for tinnitus perception and auditory plasticity. Mol Pharmacol (2008) 0.90

Thyroid hormone receptor alpha1 is a critical regulator for the expression of ion channels during final differentiation of outer hair cells. Histochem Cell Biol (2007) 0.90

Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form. Hum Mol Genet (2008) 0.90

Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells. J Neurosci (2013) 0.89

Prenatal dexamethasone impairs behavior and the activation of the BDNF exon IV promoter in the paraventricular nucleus in adult offspring. Endocrinology (2008) 0.88

Deafness in TRbeta mutants is caused by malformation of the tectorial membrane. J Neurosci (2009) 0.88

Herpes simplex virus type 1-mediated transfer of neurotrophin-3 stimulates survival of chicken auditory sensory neurons. Neurosci Lett (2002) 0.85

Salicylate alters the expression of calcium response transcription factor 1 in the cochlea: implications for brain-derived neurotrophic factor transcriptional regulation. Mol Pharmacol (2008) 0.85

AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation. FASEB J (2012) 0.84

Development and function of the voltage-gated sodium current in immature mammalian cochlear inner hair cells. PLoS One (2012) 0.84

BDNF mRNA expression and protein localization are changed in age-related hearing loss. Neurobiol Aging (2006) 0.84

The function of BDNF in the adult auditory system. Neuropharmacology (2013) 0.83

Increased noise sensitivity and altered inner ear MENA distribution in VASP-/- mice. Cell Tissue Res (2004) 0.83

Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons. Mol Cell Neurosci (2005) 0.83

Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells. Mol Cell Endocrinol (2013) 0.82

Hypothyroidism impairs chloride homeostasis and onset of inhibitory neurotransmission in developing auditory brainstem and hippocampal neurons. Eur J Neurosci (2008) 0.82

Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses. Open Biol (2013) 0.82

Retrocochlear function of the peripheral deafness gene Cacna1d. Hum Mol Genet (2012) 0.82

Critical role for cochlear hair cell BK channels for coding the temporal structure and dynamic range of auditory information for central auditory processing. FASEB J (2012) 0.82

α2δ3 is essential for normal structure and function of auditory nerve synapses and is a novel candidate for auditory processing disorders. J Neurosci (2014) 0.82

Expression of glycine receptors and gephyrin in the rat cochlea. Histochem Cell Biol (2008) 0.82