Published in Behav Brain Funct on February 25, 2009
The spontaneously hypertensive rat model of ADHD--the importance of selecting the appropriate reference strain. Neuropharmacology (2009) 1.48
Epigenetic mechanisms in learned fear: implications for PTSD. Neuropsychopharmacology (2012) 1.30
Photoacoustic Brain Imaging: from Microscopic to Macroscopic Scales. Neurophotonics (2014) 1.14
Criteria of validity for animal models of psychiatric disorders: focus on anxiety disorders and depression. Biol Mood Anxiety Disord (2011) 1.01
Assessing learning and memory in pigs. Anim Cogn (2011) 1.00
3D in vitro modeling of the central nervous system. Prog Neurobiol (2014) 0.93
Interindividual Variability in Stress Susceptibility: A Role for Epigenetic Mechanisms in PTSD. Front Psychiatry (2013) 0.89
Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains. Behav Brain Funct (2009) 0.86
Owner reports of attention, activity, and impulsivity in dogs: a replication study. Behav Brain Funct (2010) 0.86
Intraindividual variability (IIV) in an animal model of ADHD - the Spontaneously Hypertensive Rat. Behav Brain Funct (2010) 0.85
SYNGAP1: Mind the Gap. Front Cell Neurosci (2016) 0.84
Perspectives on zebrafish models of hallucinogenic drugs and related psychotropic compounds. ACS Chem Neurosci (2013) 0.83
Neurodevelopmental animal models of schizophrenia: role in novel drug discovery and development. Clin Schizophr Relat Psychoses (2010) 0.83
Exploring the Validity of Valproic Acid Animal Model of Autism. Exp Neurobiol (2015) 0.83
Promise and pitfalls of animal models of schizophrenia. Curr Psychiatry Rep (2010) 0.82
Involve both genetic and environmental factors to build monkey models of mental disorders. Dongwuxue Yanjiu (2014) 0.81
The role of behavior in translational models for psychopathology: functionality and dysfunctional behaviors. Neurosci Biobehav Rev (2013) 0.79
Considerations for animal models of blast-related traumatic brain injury and chronic traumatic encephalopathy. Alzheimers Res Ther (2014) 0.78
Mice repeatedly exposed to Group-A β-Haemolytic Streptococcus show perseverative behaviors, impaired sensorimotor gating, and immune activation in rostral diencephalon. Sci Rep (2015) 0.77
Models of α-synuclein aggregation in Parkinson's disease. Acta Neuropathol Commun (2014) 0.77
Considerations for Experimental Animal Models of Concussion, Traumatic Brain Injury, and Chronic Traumatic Encephalopathy-These Matters Matter. Front Neurol (2017) 0.76
A conceptual and practical guide to the behavioural evaluation of animal models of the symptomatology and therapy of schizophrenia. Cell Tissue Res (2013) 0.76
Pediatric Autoimmune Disorders Associated with Streptococcal Infections and Tourette's Syndrome in Preclinical Studies. Front Neurosci (2016) 0.75
Optimising reliability of mouse performance in behavioural testing: the major role of non-aversive handling. Sci Rep (2017) 0.75
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders. Neural Plast (2016) 0.75
Rhythmical Photic Stimulation at Alpha Frequencies Produces Antidepressant-Like Effects in a Mouse Model of Depression. PLoS One (2016) 0.75
Refining Housing, Husbandry and Care for Animals Used in Studies Involving Biotelemetry. Animals (Basel) (2014) 0.75
Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) Motor Dysfunction Modeled in Mice. Cerebellum (2016) 0.75
More than 3Rs: the importance of scientific validity for harm-benefit analysis of animal research. Lab Anim (NY) (2017) 0.75
Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice. Sci Rep (2017) 0.75
Logical fallacies in animal model research. Behav Brain Funct (2017) 0.75
A decade of contributions to understanding and ameliorating attention deficit-hyperactivity disorder. Behav Brain Funct (2016) 0.75
Postnatal treatment using curcumin supplements to amend the damage in VPA-induced rodent models of autism. BMC Complement Altern Med (2017) 0.75
G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods (2007) 50.83
The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry (2003) 21.70
Protective and damaging effects of stress mediators. N Engl J Med (1998) 18.80
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Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med (2007) 7.24
Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychol Med Monogr Suppl (1992) 7.04
Animal models of nociception. Pharmacol Rev (2001) 5.76
In silico mapping of complex disease-related traits in mice. Science (2001) 4.67
Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacologia (1968) 4.59
Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study. N Engl J Med (1992) 4.54
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure. Psychopharmacology (Berl) (2006) 4.23
Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment. Mamm Genome (1997) 4.15
Enriched environments, experience-dependent plasticity and disorders of the nervous system. Nat Rev Neurosci (2006) 4.08
Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berl) (1997) 4.07
Design, power, and interpretation of studies in the standard murine model of ALS. Amyotroph Lateral Scler (2008) 4.05
Guidelines for the design and statistical analysis of experiments using laboratory animals. ILAR J (2002) 3.96
Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet (2000) 3.92
How can we improve the pre-clinical development of drugs for stroke? Trends Neurosci (2007) 3.67
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet (2000) 3.63
Understanding mammalian genetic systems: the challenge of phenotyping in the mouse. PLoS Genet (2006) 3.14
The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci Biobehav Rev (2004) 3.10
Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era. Bioessays (2004) 3.08
Bench to bedside: the quest for quality in experimental stroke research. J Cereb Blood Flow Metab (2006) 2.99
Measuring normal and pathological anxiety-like behaviour in mice: a review. Behav Brain Res (2001) 2.98
Neuroscience: Standard model. Nature (2008) 2.90
Homology in behavioural pharmacology: an approach to animal models of human cognition. Behav Pharmacol (1998) 2.74
Different data from different labs: lessons from studies of gene-environment interaction. J Neurobiol (2003) 2.68
Modeling madness in mice: one piece at a time. Neuron (2006) 2.60
Lost in translation: treatment trials in the SOD1 mouse and in human ALS. Neurobiol Dis (2007) 2.33
Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades. Proc Natl Acad Sci U S A (2006) 2.31
How can drug discovery for psychiatric disorders be improved? Nat Rev Drug Discov (2007) 2.29
Rodent models of attention-deficit/hyperactivity disorder. Biol Psychiatry (2005) 2.28
Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav (2006) 2.12
Laboratory animal welfare: cage enrichment and mouse behaviour. Nature (2004) 2.10
Animal models of head trauma. NeuroRx (2005) 2.09
Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatics (2003) 2.09
The Mouse Phenome Project. Genetica (2004) 2.08
The validity of animal models of depression. Psychopharmacology (Berl) (1984) 2.07
Laboratory animals. Researchers pained by effort to define distress precisely. Science (2000) 2.03
Stress, depression, and anhedonia: caveats concerning animal models. Neurosci Biobehav Rev (2005) 2.00
The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proc Natl Acad Sci U S A (2007) 1.99
To model a psychiatric disorder in animals: schizophrenia as a reality test. Neuropsychopharmacology (2000) 1.89
Noise, noise sensitivity and psychiatric disorder: epidemiological and psychophysiological studies. Psychol Med Monogr Suppl (1992) 1.85
Animal models of anxiety: an ethological perspective. Braz J Med Biol Res (1997) 1.73
SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. Neurosci Lett (2001) 1.70
Improving housing conditions for laboratory mice: a review of "environmental enrichment". Lab Anim (2002) 1.69
Behaviour and the standardization fallacy. Nat Genet (2000) 1.69
Genetically engineered mouse models of neurodegenerative diseases. Nat Neurosci (2002) 1.66
Panic and phobic anxiety: defining phenotypes for genetic studies. Am J Psychiatry (1998) 1.66
Animal definition: a necessity for the validity of animal experiments? Lab Anim (2000) 1.63
Mouse functional genomics requires standardization of mouse handling and housing conditions. Mamm Genome (2004) 1.56
Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases. Pharmacol Ther (2007) 1.54
A neonatal ventral hippocampal lesion causes functional deficits in adult prefrontal cortical interneurons. J Neurosci (2008) 1.51
Pathological anxiety in animals. Vet J (2007) 1.49
Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology (Berl) (1995) 1.48
A new animal welfare concept based on allostasis. Physiol Behav (2006) 1.47
Stereotypies and other abnormal repetitive behaviors: potential impact on validity, reliability, and replicability of scientific outcomes. ILAR J (2005) 1.47
Genetic and environmental influences on sexual orientation and its correlates in an Australian twin sample. J Pers Soc Psychol (2000) 1.42
Is the use of animals in biomedical research still necessary in 2002? Unfortunately, "yes". Altern Lab Anim (2004) 1.42
Emotional endophenotypes in evolutionary psychiatry. Prog Neuropsychopharmacol Biol Psychiatry (2006) 1.39
Using animal models to test a neurodevelopmental hypothesis of schizophrenia. J Psychiatry Neurosci (2004) 1.39
Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis. Biol Psychiatry (1999) 1.39
Animal models of mood disorders: Recent developments. Curr Opin Psychiatry (2007) 1.38
MuTrack: a genome analysis system for large-scale mutagenesis in the mouse. BMC Bioinformatics (2004) 1.38
Environmental bias? Effects of housing conditions, laboratory environment and experimenter on behavioral tests. Genes Brain Behav (2006) 1.35
Deconstructing psychosis with human brain imaging. Schizophr Bull (2007) 1.35
Basal ganglia and limbic system pathology in schizophrenia. A morphometric study of brain volume and shrinkage. Arch Gen Psychiatry (1985) 1.35
Functional genomics in the mouse: phenotype-based mutagenesis screens. Genome Res (1998) 1.35
Different rankings of inbred mouse strains on the Morris maze and a refined 4-arm water escape task. Behav Brain Res (2005) 1.32
A review of the evidence from family, twin and adoption studies for a genetic contribution to adult psychiatric disorders. Int Rev Psychiatry (2004) 1.32
Ontologies for the description of mouse phenotypes. Comp Funct Genomics (2004) 1.31
Drug discrimination in neurobiology. Pharmacol Biochem Behav (1999) 1.30
Do animal models of anxiety predict anxiolytic-like effects of antidepressants? Psychopharmacology (Berl) (2002) 1.30
In need of high-throughput behavioral systems. Drug Discov Today (2002) 1.29
Behavioral phenotyping of mouse models of neurodevelopmental disorders: relevant social behavior patterns across the life span. Behav Brain Res (2006) 1.27
Evidence for altered trisynaptic circuitry in schizophrenic hippocampus. Biol Psychiatry (1999) 1.25
Nutritional genomics: the next frontier in the postgenomic era. Physiol Genomics (2004) 1.24
Predictive validity of animal pain models? A comparison of the pharmacokinetic-pharmacodynamic relationship for pain drugs in rats and humans. Neuropharmacology (2008) 1.22
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia. Biol Psychiatry (2007) 1.22
Replicating empirical research in behavioral ecology: how and why it should be done but rarely ever is. Q Rev Biol (2006) 1.21
Alterations in dendritic morphology of prefrontal cortical and nucleus accumbens neurons in post-pubertal rats after neonatal excitotoxic lesions of the ventral hippocampus. Neuroscience (2005) 1.20
A hitchhiker's guide to behavioral analysis in laboratory rodents. Genes Brain Behav (2006) 1.20
Animal models of behavioral dysfunctions: basic concepts and classifications, and an evaluation strategy. Brain Res Rev (2006) 1.17
Reduction of the parahippocampal gyrus and the hippocampus in patients with chronic schizophrenia. Br J Psychiatry (1999) 1.17
Natural animal models of human psychiatric conditions: assessment of mechanism and validity. Prog Neuropsychopharmacol Biol Psychiatry (2000) 1.16
How valuable are animal models in defining antidepressant activity? Hum Psychopharmacol (2001) 1.16
Gene-environment interactions differentially affect mouse strain behavioral parameters. Mamm Genome (2006) 1.14
Rodent models of depression: reexamining validity without anthropomorphic inference. Crit Rev Neurobiol (2003) 1.13
Behavioral phenotyping enhanced--beyond (environmental) standardization. Genes Brain Behav (2002) 1.12
Early behavioural changes in mice infected with BSE and scrapie: automated home cage monitoring reveals prion strain differences. Eur J Neurosci (2002) 1.12
The broken mouse: the role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Curr Opin Neurobiol (2000) 1.10
Cross-species studies of sensorimotor gating of the startle reflex. Ann N Y Acad Sci (1999) 1.10
Disruption of prepulse inhibition of startle reflex in a neurodevelopmental model of schizophrenia: reversal by clozapine, olanzapine and risperidone but not by haloperidol. Neuropsychopharmacology (2002) 1.10
Validating psychiatric endophenotypes: inhibitory control and attention deficit hyperactivity disorder. Neurosci Biobehav Rev (2007) 1.10
Investigating gene-to-behavior pathways in psychiatric disorders: the use of a comprehensive behavioral test battery on genetically engineered mice. Ann N Y Acad Sci (2006) 1.09
Behavioral phenotyping of transgenic and knockout mice: practical concerns and potential pitfalls. ILAR J (2006) 1.08
Standardizing tests of mouse behavior: reasons, recommendations, and reality. Physiol Behav (2001) 1.08
Construct validity of the animal latent inhibition model of selective attention deficits in schizophrenia. Schizophr Bull (2005) 1.08
Identifying and hurdling obstacles to translational research. Nat Rev Immunol (2007) 1.07
Hippocampal volume reduction in schizophrenia: effects of genetic risk and pregnancy and birth complications. Biol Psychiatry (1999) 1.07
Pathological anxiety in animals. Vet J (2007) 1.49
Learning-related changes in response patterns of prefrontal neurons during instrumental conditioning. Behav Brain Res (2003) 1.11
Cognitive performance of low- and normal-birth-weight piglets in a spatial hole-board discrimination task. Pediatr Res (2012) 0.98
The appetitively motivated "cognitive" holeboard: a family of complex spatial discrimination tasks for assessing learning and memory. Neurosci Biobehav Rev (2011) 0.96
The impact of transportation on physiological and behavioral parameters in Wistar rats: implications for acclimatization periods. ILAR J (2012) 0.96
The pig as a model animal for studying cognition and neurobehavioral disorders. Curr Top Behav Neurosci (2011) 0.90
Not all mice are equal: welfare implications of behavioural habituation profiles in four 129 mouse substrains. PLoS One (2012) 0.87
Predictability of painful stimulation modulates the somatosensory-evoked potential in the rat. PLoS One (2013) 0.87
Performance of conventional pigs and Göttingen miniature pigs in a spatial holeboard task: effects of the putative muscarinic cognition impairer Biperiden. Behav Brain Funct (2013) 0.86
Optimizing the dosing interval of buprenorphine in a multimodal postoperative analgesic strategy in the rat: minimizing side-effects without affecting weight gain and food intake. Lab Anim (2012) 0.86
Mild neonatal hypoxia-ischemia induces long-term motor- and cognitive impairments in mice. Brain Behav Immun (2009) 0.85
Susceptibility of a potential animal model for pathological anxiety to chronic mild stress. Behav Brain Res (2010) 0.83
Successive and conditional discrimination learning in pigs. Anim Cogn (2013) 0.83
A test to identify judgement bias in mice. Behav Brain Res (2012) 0.82
Impact of anxiety profiles on cognitive performance in BALB/c and 129P2 mice. Cogn Affect Behav Neurosci (2012) 0.81
The d-amphetamine-treated Göttingen miniature pig: an animal model for assessing behavioral effects of antipsychotics. Psychopharmacology (Berl) (2009) 0.78
Expression of CRFR1 and Glu5R mRNA in different brain areas following repeated testing in mice that differ in habituation behaviour. Behav Brain Res (2013) 0.78
Behavioural habituation to novelty and brain area specific immediate early gene expression in female mice of two inbred strains. Behav Brain Res (2010) 0.78
Decision-making under risk and ambiguity in low-birth-weight pigs. Anim Cogn (2014) 0.77
Differential effects of diazepam and MPEP on habituation and neuro-behavioural processes in inbred mice. Behav Brain Funct (2012) 0.75