PubRank

Sheena McGowan

Author PubWeight™ 19.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An overview of the serpin superfamily. Genome Biol 2006 2.14
2 Federated repositories of X-ray diffraction images. Acta Crystallogr D Biol Crystallogr 2008 1.33
3 The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis. J Mol Biol 2006 1.23
4 Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials. Trends Biochem Sci 2009 1.21
5 The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates. PLoS Pathog 2010 1.10
6 Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases. Proc Natl Acad Sci U S A 2011 1.07
7 Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. PLoS One 2012 1.00
8 Functional analysis of the VirSR phosphorelay from Clostridium perfringens. PLoS One 2009 0.98
9 Structural mechanisms of inactivation in scabies mite serine protease paralogues. J Mol Biol 2009 0.94
10 Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase. J Med Chem 2011 0.94
11 DNA accelerates the inhibition of human cathepsin V by serpins. J Biol Chem 2007 0.92
12 Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum. J Med Chem 2013 0.91
13 X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP. J Mol Biol 2012 0.87
14 A pharmacological and biochemical examination of the geographical variation of Chironex fleckeri venom. Toxicol Lett 2009 0.86
15 Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors. J Med Chem 2014 0.83
16 Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO. Biochemistry 2014 0.80
17 Synthesis of gallinamide A analogues as potent falcipain inhibitors and antimalarials. J Med Chem 2014 0.78
18 X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17. Proteins 2015 0.78
19 Conformational change in the chromatin remodelling protein MENT. PLoS One 2009 0.78
20 Identification of the molecular basis of inhibitor selectivity between the human and streptococcal type I methionine aminopeptidases. J Med Chem 2015 0.76
21 Isolation and characterization of the nuclear serpin MENT. Methods Enzymol 2011 0.75