PubRank

Raymond J Monnat

Author PubWeight™ 54.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat Cell Biol 2007 4.14
2 Computational redesign of endonuclease DNA binding and cleavage specificity. Nature 2006 4.06
3 Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases. Nat Rev Mol Cell Biol 2007 2.56
4 Design, activity, and structure of a highly specific artificial endonuclease. Mol Cell 2002 2.25
5 Homologous recombination resolution defect in werner syndrome. Mol Cell Biol 2002 2.21
6 A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature 2011 2.20
7 Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI. J Mol Biol 2003 1.93
8 DNA polymerases and human disease. Nat Rev Genet 2008 1.88
9 Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev 2003 1.84
10 The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. Cell Cycle 2008 1.83
11 Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease. Proc Natl Acad Sci U S A 2009 1.79
12 Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol 2013 1.67
13 Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation. Mol Cell Biol 2010 1.50
14 Assessment of protein dynamics and DNA repair following generation of DNA double-strand breaks at defined genomic sites. Nat Protoc 2008 1.49
15 Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication. Mol Cell Biol 2009 1.45
16 Functional role of the Werner syndrome RecQ helicase in human fibroblasts. Aging Cell 2007 1.32
17 Spectrum and risk of neoplasia in Werner syndrome: a systematic review. PLoS One 2013 1.23
18 Microfluidic-assisted analysis of replicating DNA molecules. Nat Protoc 2009 1.19
19 Metal-dependent DNA cleavage mechanism of the I-CreI LAGLIDADG homing endonuclease. Biochemistry 2004 1.18
20 A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions. Mol Cell Biol 2005 1.15
21 Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins. Nucleic Acids Res 2009 1.14
22 The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Cancer Res 2010 1.14
23 The unexpected landscape of in vivo somatic mutation in a human epithelial cell lineage. Proc Natl Acad Sci U S A 2002 1.10
24 Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases. Nucleic Acids Res 2007 1.07
25 The Werner syndrome protein has separable recombination and survival functions. DNA Repair (Amst) 2004 1.05
26 Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. J Biol Chem 2012 0.98
27 Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering. Nucleic Acids Res 2011 0.97
28 PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks. DNA Repair (Amst) 2013 0.90
29 Altered target site specificity variants of the I-PpoI His-Cys box homing endonuclease. Nucleic Acids Res 2007 0.88
30 The Werner syndrome helicase is a cofactor for HIV-1 long terminal repeat transactivation and retroviral replication. J Biol Chem 2007 0.88
31 Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation. Proc Natl Acad Sci U S A 2013 0.88
32 Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers. Transl Oncol 2013 0.87
33 Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase. DNA Repair (Amst) 2009 0.83
34 Parallel microfluidic chemosensitivity testing on individual slice cultures. Lab Chip 2014 0.82
35 The mitochondrial and chloroplast genomes of the haptophyte Chrysochromulina tobin contain unique repeat structures and gene profiles. BMC Genomics 2014 0.81
36 Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications. Nucleic Acids Res 2011 0.79
37 Diabetes mellitus and cancer in Werner syndrome. Acta Diabetol 2013 0.76
38 Rapid assessment of RNAi-mediated protein depletion by selected reaction monitoring mass spectrometry. J Proteome Res 2013 0.76
39 Identification and analysis of genomic homing endonuclease target sites. Methods Mol Biol 2014 0.75
40 Homing endonuclease target site specificity defined by sequential enrichment and next-generation sequencing of highly complex target site libraries. Methods Mol Biol 2014 0.75
41 Quantifying the information content of homing endonuclease target sites by single base pair profiling. Methods Mol Biol 2014 0.75
42 Conversion of a laboratory-based test for phenylalanine detection to a simple paper-based format and implications for PKU screening in low-resource settings. Analyst 2015 0.75