| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Effects of sugammadex on activated partial thromboplastin time and prothrombin time in healthy subjects.
|
Int J Clin Pharmacol Ther
|
2014
|
1.43
|
|
2
|
Stimulation programs for pediatric drug research--do children really benefit?
|
Eur J Pediatr
|
2007
|
1.31
|
|
3
|
Erythropoietin doping in cycling: lack of evidence for efficacy and a negative risk-benefit.
|
Br J Clin Pharmacol
|
2013
|
1.28
|
|
4
|
A phase I dose-escalation and bioequivalence study of a trastuzumab biosimilar in healthy male volunteers.
|
Clin Drug Investig
|
2014
|
1.15
|
|
5
|
A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema.
|
J Allergy Clin Immunol
|
2005
|
1.14
|
|
6
|
Physiological thyroid hormone levels regulate numerous skeletal muscle transcripts.
|
J Clin Endocrinol Metab
|
2009
|
1.14
|
|
7
|
Evaluation of furosemide regimens in neonates treated with extracorporeal membrane oxygenation.
|
Crit Care
|
2006
|
1.12
|
|
8
|
Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers.
|
Br J Clin Pharmacol
|
2007
|
1.09
|
|
9
|
Acute kidney injury during therapy with an antisense oligonucleotide directed against PCSK9.
|
Am J Kidney Dis
|
2013
|
1.00
|
|
10
|
Pharmacokinetics of oral fumarates in healthy subjects.
|
Br J Clin Pharmacol
|
2004
|
1.00
|
|
11
|
Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting.
|
J Clin Endocrinol Metab
|
2009
|
0.95
|
|
12
|
Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma.
|
Am J Respir Crit Care Med
|
2006
|
0.93
|
|
13
|
Midazolam pharmacokinetics in morbidly obese patients following semi-simultaneous oral and intravenous administration: a comparison with healthy volunteers.
|
Clin Pharmacokinet
|
2014
|
0.90
|
|
14
|
High circulating thyrotropin levels in obese women are reduced after body weight loss induced by caloric restriction.
|
J Clin Endocrinol Metab
|
2005
|
0.89
|
|
15
|
Lack of a clinically relevant effect of sugammadex on anti-Xa activity or activated partial thromboplastin time following pretreatment with either unfractionated or low-molecular-weight heparin in healthy subjects.
|
Int J Clin Pharmacol Ther
|
2014
|
0.89
|
|
16
|
Comparison of the impact of vaginal and oral administration of combined hormonal contraceptives on hepatic proteins sensitive to estrogen.
|
Contraception
|
2007
|
0.87
|
|
17
|
Urinary kidney biomarkers for early detection of nephrotoxicity in clinical drug development.
|
Br J Clin Pharmacol
|
2014
|
0.87
|
|
18
|
An exploratory study with an adaptive continuous intravenous furosemide regimen in neonates treated with extracorporeal membrane oxygenation.
|
Crit Care
|
2007
|
0.86
|
|
19
|
Absence of tolerance and toxicity to high-dose continuous intravenous furosemide in haemodynamically unstable infants after cardiac surgery.
|
Br J Clin Pharmacol
|
2007
|
0.85
|
|
20
|
Development of an optimal furosemide infusion strategy in infants with modeling and simulation.
|
Clin Pharmacol Ther
|
2002
|
0.85
|
|
21
|
No clinically relevant interaction between sugammadex and aspirin on platelet aggregation and coagulation parameters.
|
Int J Clin Pharmacol Ther
|
2013
|
0.85
|
|
22
|
Blunted lipolytic response to fasting in abdominally obese women: evidence for involvement of hyposomatotropism.
|
Am J Clin Nutr
|
2003
|
0.83
|
|
23
|
Diuretics in pediatrics : current knowledge and future prospects.
|
Paediatr Drugs
|
2006
|
0.82
|
|
24
|
Pharmacokinetics and pharmacodynamics of the erythropoietin Mimetibody construct CNTO 528 in healthy subjects.
|
Clin Pharmacokinet
|
2009
|
0.82
|
|
25
|
Abdominal visceral and subcutaneous fat increase, insulin resistance and hyperlipidemia in testicular cancer patients treated with cisplatin-based chemotherapy.
|
Acta Oncol
|
2013
|
0.82
|
|
26
|
Pharmacokinetics and central nervous system effects of the novel dopamine D2 receptor antagonist JNJ-37822681.
|
J Psychopharmacol
|
2011
|
0.82
|
|
27
|
A phase I, single and fractionated, ascending-dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietin mimetic antibody fusion protein (CNTO 528) in healthy male subjects.
|
J Clin Pharmacol
|
2008
|
0.81
|
|
28
|
Increased circadian prolactin release is blunted after body weight loss in obese premenopausal women.
|
Am J Physiol Endocrinol Metab
|
2005
|
0.81
|
|
29
|
Motilin effects on the proximal stomach in patients with functional dyspepsia and healthy volunteers.
|
Am J Physiol Gastrointest Liver Physiol
|
2003
|
0.81
|
|
30
|
The need for improvement of the treatment of advanced and metastatic cervical cancer, the rationale for combined chemo-immunotherapy.
|
Anticancer Agents Med Chem
|
2014
|
0.81
|
|
31
|
Autonomic nervous system function in chronic exogenous subclinical thyrotoxicosis and the effect of restoring euthyroidism.
|
J Clin Endocrinol Metab
|
2008
|
0.80
|
|
32
|
A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults.
|
Clin Pharmacokinet
|
2013
|
0.80
|
|
33
|
Comparison of body surface area versus weight-based growth hormone dosing for girls with Turner syndrome.
|
Horm Res Paediatr
|
2014
|
0.79
|
|
34
|
Creating a culture of thoughtful prescribing.
|
Med Teach
|
2009
|
0.79
|
|
35
|
Tasquinimod: a novel drug in advanced prostate cancer.
|
Future Oncol
|
2013
|
0.79
|
|
36
|
Quantification of heparin-induced TFPI release: a maximum release at low heparin dose.
|
Br J Clin Pharmacol
|
2002
|
0.78
|
|
37
|
Short-term overt hypothyroidism induces sympathovagal imbalance in thyroidectomized differentiated thyroid carcinoma patients.
|
Clin Endocrinol (Oxf)
|
2009
|
0.78
|
|
38
|
Metabolic profile of a continuous versus a cyclic low-dose combined oral contraceptive after one year of use.
|
Eur J Contracept Reprod Health Care
|
2011
|
0.78
|
|
39
|
Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects.
|
Am J Clin Nutr
|
2006
|
0.77
|
|
40
|
Relationship between airway responsiveness to neurokinin A and methacholine in asthma.
|
Pulm Pharmacol Ther
|
2005
|
0.77
|
|
41
|
Hydrolyzed casein decreases postprandial glucose concentrations in T2DM patients irrespective of leucine content.
|
J Diet Suppl
|
2011
|
0.77
|
|
42
|
Autonomic nervous system activity in diabetic and healthy obese female subjects and the effect of distinct weight loss strategies.
|
Eur J Endocrinol
|
2013
|
0.77
|
|
43
|
Evaluation of lecithinized human recombinant super oxide dismutase as cardioprotectant in anthracycline-treated breast cancer patients.
|
Br J Clin Pharmacol
|
2014
|
0.77
|
|
44
|
Pharmacokinetics of PC-SOD, a lecithinized recombinant superoxide dismutase, after single- and multiple-dose administration to healthy Japanese and Caucasian volunteers.
|
J Clin Pharmacol
|
2007
|
0.77
|
|
45
|
Growth hormone blunts protein oxidation and promotes protein turnover to a similar extent in abdominally obese and normal-weight women.
|
J Clin Endocrinol Metab
|
2002
|
0.77
|
|
46
|
Increased impact of a contraceptive vaginal ring with ethinyl estradiol and nestorone on C-reactive protein.
|
Steroids
|
2012
|
0.77
|
|
47
|
Comparative effects of a contraceptive vaginal ring delivering a nonandrogenic progestin and continuous ethinyl estradiol and a combined oral contraceptive containing levonorgestrel on hemostasis variables.
|
Am J Obstet Gynecol
|
2006
|
0.77
|
|
48
|
Modeling the influence of growth hormone on lipolysis.
|
J Pharmacokinet Pharmacodyn
|
2002
|
0.76
|
|
49
|
Modulation of vasoactivity and platelet aggregation by selective 5-HT receptor antagonism in humans.
|
J Cardiovasc Pharmacol
|
2011
|
0.76
|
|
50
|
Effects of a nonpeptide motilin receptor antagonist on proximal gastric motor function.
|
Br J Clin Pharmacol
|
2004
|
0.76
|
|
51
|
Introduction to haemostasis from a pharmacodynamic perspective.
|
Br J Clin Pharmacol
|
2011
|
0.75
|
|
52
|
Hyposomatotropism blunts lipolysis in abdominally obese women.
|
J Clin Endocrinol Metab
|
2002
|
0.75
|
|
53
|
Measurement of collagen- and serotonin-induced platelet aggregation in whole blood.
|
Expert Rev Clin Pharmacol
|
2010
|
0.75
|
|
54
|
A simplified oral flucloxacillin absorption test for patients requiring long-term treatment.
|
Ther Drug Monit
|
2012
|
0.75
|
|
55
|
Hurdles in modern trial management: as overbureaucracy and commercialization of clinical trials suffocate independent academic research, it's time for a change.
|
Eur Urol
|
2009
|
0.75
|
|
56
|
Evaluation of a bedside device to assess the activated partial thromboplastin time for heparin monitoring in infants.
|
Blood Coagul Fibrinolysis
|
2013
|
0.75
|
|
57
|
Clinically important interaction between tedisamil and verapamil.
|
J Clin Pharmacol
|
2009
|
0.75
|
|
58
|
Absence of interaction of fondaparinux sodium with aspirin and piroxicam in healthy male volunteers.
|
Clin Pharmacokinet
|
2002
|
0.75
|
|
59
|
Endothelial binding of recombinant tissue plasminogen activator: quantification in vivo using a recirculatory model.
|
J Pharmacokinet Pharmacodyn
|
2003
|
0.75
|
|
60
|
Local tissue factor pathway inhibitor release in the human forearm.
|
Thromb Haemost
|
2003
|
0.75
|
|
61
|
The synthetic pentasaccharide fondaparinux sodium does not interact with oral warfarin.
|
Clin Pharmacokinet
|
2002
|
0.75
|
|
62
|
Discriminant analysis of the metabolic effects of a new combined contraceptive vaginal ring containing Nestorone/EE vs. a second-generation oral contraceptive containing levonorgestrel/EE.
|
Contraception
|
2012
|
0.75
|