Published in FASEB J on March 17, 2009
The blood-testis barrier and its implications for male contraception. Pharmacol Rev (2011) 2.10
A local autocrine axis in the testes that regulates spermatogenesis. Nat Rev Endocrinol (2010) 2.03
Spermiation: The process of sperm release. Spermatogenesis (2011) 1.78
Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis. Proc Natl Acad Sci U S A (2010) 1.49
An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective. Crit Rev Biochem Mol Biol (2009) 1.33
Cytoskeletal dynamics and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 1.19
Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3. Biochem J (2011) 1.15
Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes. Reproduction (2011) 1.11
Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes. Endocrinology (2013) 1.08
The N and C termini of ZO-1 are surrounded by distinct proteins and functional protein networks. J Biol Chem (2013) 1.06
c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes. Int J Biochem Cell Biol (2011) 1.06
Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis. Spermatogenesis (2011) 1.03
Mono-(2-ethylhexyl) phthalate-induced disruption of junctional complexes in the seminiferous epithelium of the rodent testis is mediated by MMP2. Biol Reprod (2009) 1.03
Interleukin-1alpha is a regulator of the blood-testis barrier. FASEB J (2010) 1.01
rpS6 Regulates blood-testis barrier dynamics by affecting F-actin organization and protein recruitment. Endocrinology (2012) 0.99
Adjudin disrupts spermatogenesis via the action of some unlikely partners: Eps8, Arp2/3 complex, drebrin E, PAR6 and 14-3-3. Spermatogenesis (2011) 0.98
c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution. Am J Physiol Endocrinol Metab (2012) 0.96
Rictor/mTORC2 regulates blood-testis barrier dynamics via its effects on gap junction communications and actin filament network. FASEB J (2013) 0.95
Environmental toxicants and male reproductive function. Spermatogenesis (2011) 0.94
CHD5 is required for spermiogenesis and chromatin condensation. Mech Dev (2013) 0.94
Associations between testicular hormones at adolescence and attendance at chlorinated swimming pools during childhood. Int J Androl (2011) 0.94
p-FAK-Tyr(397) regulates spermatid adhesion in the rat testis via its effects on F-actin organization at the ectoplasmic specialization. Am J Physiol Endocrinol Metab (2013) 0.93
Actin binding proteins and spermiogenesis: Some unexpected findings. Spermatogenesis (2011) 0.91
EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology (2014) 0.90
Actin binding proteins, spermatid transport and spermiation. Semin Cell Dev Biol (2014) 0.90
Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration. Elife (2015) 0.89
The myotubularin family of lipid phosphatases in disease and in spermatogenesis. Biochem J (2011) 0.88
Germ cell transport across the seminiferous epithelium during spermatogenesis. Physiology (Bethesda) (2014) 0.87
Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis. Endocrinology (2012) 0.87
Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2. Int Rev Cell Mol Biol (2013) 0.86
Regulation of actin dynamics and protein trafficking during spermatogenesis--insights into a complex process. Crit Rev Biochem Mol Biol (2013) 0.86
Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins. Hum Reprod (2014) 0.86
Signalling pathways regulating the blood-testis barrier. Int J Biochem Cell Biol (2012) 0.85
Focal adhesion kinase is a regulator of F-actin dynamics: New insights from studies in the testis. Spermatogenesis (2013) 0.84
Fascin 1 is an actin filament-bundling protein that regulates ectoplasmic specialization dynamics in the rat testis. Am J Physiol Endocrinol Metab (2014) 0.84
Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis. Semin Cell Dev Biol (2014) 0.84
Toxicants target cell junctions in the testis: Insights from the indazole-carboxylic acid model. Spermatogenesis (2015) 0.84
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep (2016) 0.84
Breast cancer resistance protein regulates apical ectoplasmic specialization dynamics stage specifically in the rat testis. Am J Physiol Endocrinol Metab (2013) 0.83
Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis. Spermatogenesis (2012) 0.82
Actin cross-linking protein palladin and spermatogenesis. Spermatogenesis (2013) 0.82
Filamin A: A regulator of blood-testis barrier assembly during post-natal development. Spermatogenesis (2012) 0.82
Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption. FASEB J (2015) 0.81
Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice. Andrology (2012) 0.81
N-wasp is required for structural integrity of the blood-testis barrier. PLoS Genet (2014) 0.81
Focal adhesion kinase and actin regulatory/binding proteins that modulate F-actin organization at the tissue barrier: Lesson from the testis. Tissue Barriers (2013) 0.81
New insights into FAK function and regulation during spermatogenesis. Histol Histopathol (2014) 0.80
Formin 1 Regulates Ectoplasmic Specialization in the Rat Testis Through Its Actin Nucleation and Bundling Activity. Endocrinology (2015) 0.80
The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics. Cell Mol Life Sci (2011) 0.80
The apical ectoplasmic specialization-blood-testis barrier functional axis is a novel target for male contraception. Adv Exp Med Biol (2012) 0.80
Polarity proteins and actin regulatory proteins are unlikely partners that regulate cell adhesion in the seminiferous epithelium during spermatogenesis. Histol Histopathol (2011) 0.79
p70 S6 kinase and actin dynamics: A perspective. Spermatogenesis (2012) 0.79
Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*. PLoS One (2013) 0.79
The apical ES-BTB-BM functional axis is an emerging target for toxicant-induced infertility. Trends Mol Med (2013) 0.78
Slc15a1 is involved in the transport of synthetic F5-peptide into the seminiferous epithelium in adult rat testes. Sci Rep (2015) 0.78
F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis. Oncotarget (2016) 0.78
Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology (2016) 0.77
Regulation of blood-testis barrier by actin binding proteins and protein kinases. Reproduction (2015) 0.77
Sertoli cells are the target of environmental toxicants in the testis - a mechanistic and therapeutic insight. Expert Opin Ther Targets (2015) 0.77
Formins: Actin nucleators that regulate cytoskeletal dynamics during spermatogenesis. Spermatogenesis (2015) 0.77
Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress. Mol Biol Cell (2015) 0.77
Plastins regulate ectoplasmic specialization via its actin bundling activity on microfilaments in the rat testis. Asian J Androl (2016) 0.76
Tubulobulbar complex: cytoskeletal remodeling to release spermatozoa. Reprod Biol Endocrinol (2012) 0.76
Adjudin disrupts spermatogenesis by targeting drug transporters: Lesson from the breast cancer resistance protein (BCRP). Spermatogenesis (2013) 0.76
High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial Cells. Toxicol Sci (2016) 0.76
GAR22β regulates cell migration, sperm motility, and axoneme structure. Mol Biol Cell (2015) 0.75
Actin binding proteins in blood-testis barrier function. Curr Opin Endocrinol Diabetes Obes (2015) 0.75
RAI14 (retinoic acid induced protein 14) is an F-actin regulator: Lesson from the testis. Spermatogenesis (2013) 0.75
Does cell polarity matter during spermatogenesis? Spermatogenesis (2016) 0.75
Is toxicant-induced Sertoli cell injury in vitro a useful model to study molecular mechanisms in spermatogenesis? Semin Cell Dev Biol (2016) 0.75
Sertolin mediates blood-testis barrier restructuring. Endocrinology (2014) 0.75
Effective Delivery of Male Contraceptives Behind the Blood-Testis Barrier (BTB) - Lesson from Adjudin. Curr Med Chem (2016) 0.75
Expression and localization of myosin VI in developing mouse spermatids. Histochem Cell Biol (2017) 0.75
Cell polarity, cell adhesion, and spermatogenesis: role of cytoskeletons. F1000Res (2017) 0.75
Rho and Rac take center stage. Cell (2004) 10.64
Kinetics of spermatogenesis in mammals: seminiferous epithelium cycle and spermatogonial renewal. Physiol Rev (1972) 3.74
Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev (2004) 3.64
Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc Natl Acad Sci U S A (2003) 2.89
Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol (1998) 2.75
Beyond polymer polarity: how the cytoskeleton builds a polarized cell. Nat Rev Mol Cell Biol (2008) 2.53
Eps8 controls actin-based motility by capping the barbed ends of actin filaments. Nat Cell Biol (2004) 2.40
Androgens regulate the permeability of the blood-testis barrier. Proc Natl Acad Sci U S A (2005) 2.25
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells. FASEB J (2008) 2.13
Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases. J Biol Chem (2005) 2.09
Control of actin assembly dynamics in cell motility. J Biol Chem (2007) 2.03
Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex. Nat Cell Biol (2006) 1.92
Actin in membrane trafficking. Curr Opin Cell Biol (2007) 1.78
Anchoring junctions as drug targets: role in contraceptive development. Pharmacol Rev (2008) 1.76
Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis. Biochim Biophys Acta (2007) 1.74
Androgen receptor in sertoli cell is essential for germ cell nursery and junctional complex formation in mouse testes. Endocrinology (2006) 1.69
Proliferation of Sertoli cells in fetal and postnatal rats: a quantitative autoradiographic study. Anat Rec (1982) 1.68
Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes. J Biol Chem (2006) 1.66
Coupling membrane protrusion and cell adhesion. J Cell Sci (2003) 1.61
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. J Cell Biol (2001) 1.58
Regulation of the seminiferous epithelium. Endocr Rev (1982) 1.57
An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis. Proc Natl Acad Sci U S A (2008) 1.55
Ectoplasmic specialization: a friend or a foe of spermatogenesis? Bioessays (2007) 1.52
The interplay of collagen IV, tumor necrosis factor-alpha, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis. Endocrinology (2003) 1.50
TGF-beta3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study. Endocrinology (2003) 1.44
Unique and multifunctional adhesion junctions in the testis: ectoplasmic specializations. Arch Histol Cytol (2000) 1.37
Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis. Biol Reprod (2001) 1.34
A 22-amino acid synthetic peptide corresponding to the second extracellular loop of rat occludin perturbs the blood-testis barrier and disrupts spermatogenesis reversibly in vivo. Biol Reprod (2001) 1.31
The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell (2003) 1.21
Eps8 in the midst of GTPases. Int J Biochem Cell Biol (2002) 1.20
The blood-testis barrier and Sertoli cell junctions: structural considerations. Microsc Res Tech (1992) 1.19
Ability of trypsin in mimicking germ cell factors that affect Sertoli cell secretory function. J Cell Physiol (1996) 1.13
A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctions. Cell Motil Cytoskeleton (2002) 1.11
Role of tissue inhibitor of metalloproteases-1 in junction dynamics in the testis. J Androl (2003) 1.09
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway. Endocrinology (2004) 1.07
Identification of hormonally responsive proteins in primary Sertoli cell culture medium by anion-exchange high performance liquid chromatography. Endocrinology (1986) 1.07
Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase. J Biol Chem (2007) 1.06
Cytoskeletal involvement in spermiation and sperm transport. Tissue Cell (1989) 1.04
Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation. Endocrinology (2008) 1.03
The consequences of actin disruption at Sertoli ectoplasmic specialization sites facing spermatids after in vivo exposure of rat testis to cytochalasin D. Biol Reprod (1988) 1.02
Ectoplasmic specializations in the Sertoli cell: new vistas based on genetic defects and testicular toxicology. Anat Sci Int (2003) 0.96
Germ cell-conditioned medium contains multiple factors that modulate the secretion of testins, clusterin, and transferrin by Sertoli cells. J Androl (1993) 0.96
Glycerol disrupts tight junction-associated actin microfilaments, occludin, and microtubules in Sertoli cells. J Androl (2000) 0.95
Rho GTPases and spermatogenesis. Biochim Biophys Acta (2003) 0.94
Intratesticular injection as a method to assess the potential toxicity of various agents and to study mechanisms of normal spermatogenesis. Gamete Res (1987) 0.92
Rat testis motor proteins associated with spermatid translocation (dynein) and spermatid flagella (kinesin-II). Biol Reprod (1999) 0.90
Dynein and plus-end microtubule-dependent motors are associated with specialized Sertoli cell junction plaques (ectoplasmic specializations). J Cell Sci (2000) 0.90
Estrogens potentiate the stimulatory effects of follicle-stimulating hormone on N-cadherin messenger ribonucleic acid levels in cultured mouse Sertoli cells. Endocrinology (1997) 0.88
A kinesin is present at unique sertoli/spermatid adherens junctions in rat and mouse testes. Biol Reprod (2007) 0.86
Sustained azoospermia in squirrel monkey, Saimiri sciureus, resulting from a single intratesticular glycerol injection. Contraception (1989) 0.84
There goes the neighbourhood: Eps8 joins the barbed-end crowd. Nat Cell Biol (2004) 0.83
Suppression of spermatogenesis without inhibition of steroidogenesis by a 1,2,3-trihydroxypropane solution. Life Sci (1984) 0.81
Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev (2004) 3.64
Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development. Physiol Rev (2002) 2.60
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells. FASEB J (2008) 2.13
The blood-testis barrier and its implications for male contraception. Pharmacol Rev (2011) 2.10
Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases. J Biol Chem (2005) 2.09
A local autocrine axis in the testes that regulates spermatogenesis. Nat Rev Endocrinol (2010) 2.03
Anchoring junctions as drug targets: role in contraceptive development. Pharmacol Rev (2008) 1.76
Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis. Biochim Biophys Acta (2007) 1.74
Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes. J Biol Chem (2006) 1.66
Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes. J Endocrinol (2006) 1.66
Regulation of blood-testis barrier dynamics: an in vivo study. J Cell Sci (2004) 1.62
An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis. Proc Natl Acad Sci U S A (2008) 1.55
Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Proc Natl Acad Sci U S A (2008) 1.53
Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis. J Cell Biol (2004) 1.53
Ectoplasmic specialization: a friend or a foe of spermatogenesis? Bioessays (2007) 1.52
The interplay of collagen IV, tumor necrosis factor-alpha, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis. Endocrinology (2003) 1.50
Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics. Proc Natl Acad Sci U S A (2009) 1.49
Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis. Proc Natl Acad Sci U S A (2010) 1.49
Adhering junction dynamics in the testis are regulated by an interplay of beta 1-integrin and focal adhesion complex-associated proteins. Endocrinology (2003) 1.49
Dynamic cross-talk between cells and the extracellular matrix in the testis. Bioessays (2004) 1.48
The blood-testis barrier: its biology, regulation, and physiological role in spermatogenesis. Curr Top Dev Biol (2005) 1.48
Cadmium-induced testicular injury. Toxicol Appl Pharmacol (2009) 1.47
Differential interactions between transforming growth factor-beta3/TbetaR1, TAB1, and CD2AP disrupt blood-testis barrier and Sertoli-germ cell adhesion. J Biol Chem (2006) 1.47
Interactions of proteases, protease inhibitors, and the beta1 integrin/laminin gamma3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biol Reprod (2003) 1.47
TGF-beta3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study. Endocrinology (2003) 1.44
Cell-cell interactions at the ectoplasmic specialization in the testis. Trends Endocrinol Metab (2004) 1.40
Transforming growth factor beta3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway. Biol Reprod (2002) 1.39
Blood-testis barrier dynamics are regulated by an engagement/disengagement mechanism between tight and adherens junctions via peripheral adaptors. Proc Natl Acad Sci U S A (2005) 1.38
Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics? Int J Biochem Cell Biol (2009) 1.38
An in vitro system to study Sertoli cell blood-testis barrier dynamics. Methods Mol Biol (2011) 1.37
Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics. Int J Biochem Cell Biol (2010) 1.37
A male contraceptive targeting germ cell adhesion. Nat Med (2006) 1.35
An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective. Crit Rev Biochem Mol Biol (2009) 1.33
Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3',5'-cyclic guanosine monophosphate/protein kinase G signaling pathway: an in vitro study. Endocrinology (2003) 1.31
Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits. Spermatogenesis (2011) 1.31
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis? Biol Reprod (2003) 1.30
Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier. Int J Biochem Cell Biol (2009) 1.29
TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study. Dev Biol (2005) 1.28
An occludin-focal adhesion kinase protein complex at the blood-testis barrier: a study using the cadmium model. Endocrinology (2009) 1.28
Focal adhesion kinase is a blood-testis barrier regulator. Proc Natl Acad Sci U S A (2009) 1.26
Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat. Proc Natl Acad Sci U S A (2012) 1.22
Cytokines and junction restructuring during spermatogenesis--a lesson to learn from the testis. Cytokine Growth Factor Rev (2005) 1.21
Protein kinases and adherens junction dynamics in the seminiferous epithelium of the rat testis. J Cell Physiol (2005) 1.21
Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes. J Endocrinol (2006) 1.21
Polarity proteins and cell-cell interactions in the testis. Int Rev Cell Mol Biol (2009) 1.21
Regulation of ectoplasmic specialization dynamics in the seminiferous epithelium by focal adhesion-associated proteins in testosterone-suppressed rat testes. Endocrinology (2004) 1.20
Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study. Biol Reprod (2003) 1.20
Cytoskeletal dynamics and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 1.19
14-3-3 Protein regulates cell adhesion in the seminiferous epithelium of rat testes. Endocrinology (2009) 1.19
Ectoplasmic specialization, a testis-specific cell-cell actin-based adherens junction type: is this a potential target for male contraceptive development? Hum Reprod Update (2004) 1.16